Grants for Special district governments - Federal

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) invites researchers to submit applications for support of clinical projects that address critical needs for clinical trial readiness in Down syndrome. This initiative seeks applications that are intended to facilitate Down syndrome research by enabling efficient and effective movement of candidate therapeutics or diagnostics towards clinical trials for Down syndrome and its co-occurring conditions, and to increase their likelihood of success through development and testing of biomarkers and clinical outcome assessment measures, development and testing of novel trial methods and recruitment strategies, or by defining the presentation and course of the co-occurring conditions in individuals with Down syndrome to enable the design of future clinical trials.

This is a special notice to provide information about the upcoming Notice of Funding Opportunity to establish APEX Accelerators in Fiscal Year 2025. The Procurement Technical Assistance Program (PTAP) was established by section 1241 of the Department of Defense (DoD) Authorization Act for Fiscal Year 1985 (Public Law 98-525) to expand the number of businesses capable of participating in government contracts. Under this announcement, the Department of Defense will award cost sharing cooperative agreements to eligible program participants who will establish or maintain APEX Accelerators. The APEX Accelerators serve as a resource for businesses to obtain information and training related to contracting opportunities with DoD, other federal agencies, state and local governments and with government prime contractors. Procurement professionals at the APEX Accelerators provide critical assistance to businesses seeking to participate in government contracts and most of the assistance they provide is free. B. Program Description/Objective: Award recipients must establish and maintain an APEX Accelerator with physical location(s) to serve as a resource for large and small businesses to obtain procurement technical assistance. Procurement technical assistance means professional, specialized assistance provided to clients that enables them to identify potential contractual opportunities and obtain or perform under contracts, innovation and technology grants, and other DoD-funded instruments, with DoD, other Federal agencies, State and/or local governments, and with Federal, State and/or local government contractors. Clients may include any business pursuing or performing these types of contracts or subcontracts at any tier. As used in this part, the terms “State” and “local government” have the meanings provided in 10 U.S.C. 4951. Innovation and technology grants refer to awards issued pursuant to the Small Business Innovation Research and/or Small Business Technology Transfer programs. You must collaborate with DoD and other Federal agencies and work cooperatively with them to accomplish the work under this award.

This funding opportunity supports multi-center clinical trials aimed at improving treatments for neurological emergencies, such as traumatic brain injury and status epilepticus, by leveraging a collaborative network and infrastructure.

This funding opportunity provides financial support to exceptional clinician scientists who contribute to the development and implementation of NCI clinical trials, ensuring their continued involvement in cancer research without being principal investigators on research project grants.

This grant provides funding for research on how HIV and substance use affect placental health and maternal outcomes, targeting a wide range of institutions and researchers focused on these critical health issues.

This grant provides funding for research projects that explore how sex hormones affect HIV progression and substance use disorders, aiming to develop new therapeutic strategies for these interconnected health issues.

This funding opportunity supports research projects that develop and test innovative strategies to improve cancer screening and preventive services for populations facing health disparities, such as racial and ethnic minorities, low-income groups, and rural communities.

This funding opportunity provides financial support to various organizations and entities to develop training and assistance programs aimed at combating opioid and stimulant misuse in rural communities.

The purpose of this Funding Opportunity Announcement (FOA) is to solicit applications for the Research Units (RUs), one of the two scientific components of the Pancreatic Cancer Detection Consortium (PCDC), to conduct research on early detection of pancreatic ductal adenocarcinoma (PDAC) and characterization of its precursor lesions to identify those patients who are at high risk of progression to cancer. The PCDC will continue to address one of the four research priorities identified in the National Cancer Institute's 2014 Scientific Framework for Pancreatic Ductal Adenocarcinoma. The PCDC will support research for the development and testing of new molecular and imaging biomarkers for detecting PDAC early and for identifying those patients at high risk of PDAC (because of genetic factors or presence of precursor lesions) who could be candidates for early intervention. The PCDC-RUs will consist of multi-disciplinary teams and will undertake studies to: identify and test biomarkers measurable in bodily fluids for early detection of PDAC and/or its precursor lesions; determine which pancreatic cysts are likely to progress to cancer; develop molecular- and/or imaging-based approaches for screening populations at high risk of PDAC; use machine learning and computational approaches towards biomarker discovery and/or validation; and conduct biomarker validation studies. The PCDC-RUs will also collect longitudinal biospecimens for building a biorepository. Each PCDC-RU is expected to participate in collaborative activities with other PCDC-RUs and share ideas, biospecimens and data within the Consortium. The other scientific component of the PCDC will be the Management and Data Coordination Unit (MDCU). The PCDC-MDCU will provide support toward study design, protocol development, statistical analysis, coordination, harmonization, data management and stewardship for the trans-PCDC collaborative projects, including biorepository building effort. The PCDC-MDCU will also supp

Grant Title: Generation III+ Small Modular Reactor Pathway to Deployment - This grant aims to accelerate the deployment of advanced small modular reactor technologies in the U.S. by providing funding to teams that demonstrate a clear plan for building and operating these reactors, thereby enhancing energy security and supporting clean energy goals.

This funding opportunity provides financial support to U.S. academic and nonprofit institutions to implement innovative programs that enhance research rigor and transparency in neuroscience, fostering a culture of high-quality scientific practices.

This funding opportunity provides financial support for researchers to explore innovative ways to integrate genomic information into clinical care, particularly focusing on diverse and underserved populations to improve health equity.

This funding opportunity provides financial support to public and nonprofit organizations for creating permanent supportive housing projects that assist individuals and families experiencing homelessness, particularly those with disabilities.

This grant provides funding to support community-driven educational initiatives that enhance college and career readiness for Indian students through culturally relevant approaches and partnerships with local tribes and educational institutions.

This funding opportunity supports multidisciplinary teams in developing and testing innovative drugs and devices to treat mental disorders, encouraging collaboration between academia and industry.

This funding opportunity supports the development and enhancement of animal models and related biological tools that are broadly applicable to various areas of biomedical research, aimed at improving our understanding of human diseases and advancing therapeutic interventions.

This grant provides funding for researchers to explore how HIV and substance use disorders affect protein interactions in microglia, aiming to uncover mechanisms that could lead to new treatments for these interconnected conditions.

This funding opportunity announcement (FOA) encourages applications for multi-center clinical trials focused on neurological emergencies. Successful applicants will collaborate and conduct the trial within the NIH SIREN Network. The NIH SIREN Clinical Coordinating Center (CCC) will work with the successful applicants to implement the proposed trial efficiently and the SIREN Data Coordinating Center (DCC) will provide statistical and data management support. The NIH SIREN hubs and their affiliated clinical sites will provide on-site implementation of the clinical protocols.The NIH SIREN Network will also be uniquely poised to collaborate with other US and international consortia necessary to conduct larger, definitive trials of promising interventions for neurological emergencies.Multi-center clinical trials in stroke treatment, recovery, or prevention supported by NINDS will be conducted in the NIH StrokeNet, and not within SIREN. Applicants do not need to be part of the existing SIREN infrastructure to apply under this FOA.

This funding opportunity provides financial support to healthcare organizations and educational institutions for developing clinical decision support systems that integrate the latest research on Long COVID care, with a focus on improving patient outcomes and equity in underserved populations.

This grant provides funding to a wide range of organizations, including governments, educational institutions, and nonprofits, to implement innovative strategies for HIV prevention and treatment in India, aiming to eliminate HIV as a public health threat.