DOD USAMRDC FY23-FY27 Broad Agency Announcement for Extramural Medical Research

The FY23–FY27 DOD USAMRDC Broad Agency Announcement (BAA) for Extramural Medical Research is issued by the Defense Health Agency (DHA) Research & Development Directorate through the U.S. Army Medical Research and Development Command (USAMRDC). This BAA invites proposals for scientific and medical research projects intended to improve health outcomes for military service members, veterans, and beneficiaries, while also providing dual-use benefits for the broader civilian population. Released on October 1, 2022, and open continuously until September 30, 2027, this opportunity is broad in scope, offering support for a wide range of medical research areas aligned with national defense strategies and operational readiness objectives. The BAA is structured to solicit proposals under several focus areas, each tied to the health and performance of the military community. These include Military Infectious Diseases, Combat Casualty Care, Traumatic Brain Injury, Psychological Health, Sensory Systems, Musculoskeletal Injury, Environmental Exposures, Directed Energy/Radiation Health, and DoD Working Dogs. The BAA supports research in various stages from basic and applied research to advanced technology development and, under specific conditions, prototyping. While clinical trials are supported, they require specific additional documentation, including regulatory approvals and IRB review. Proposals must be clearly aligned with military relevance and public benefit, with careful justification for how the research supports readiness and operational effectiveness. Applicants must follow a two-step submission process. First, a pre-application or pre-proposal must be submitted via eBRAP.org. If selected, an invitation will be issued to submit a full application through Grants.gov. Pre-applications are reviewed internally and are not provided written feedback. The final application package must align with detailed requirements, including project narrative, budget, technical and lay abstracts, statement of work, impact and transition plans, and any necessary documentation for human or animal research compliance. A comprehensive checklist and templates are provided in the General Submission Instructions, which must be used in conjunction with the BAA document. Eligibility for this funding opportunity is broad but specific. Eligible applicants include national and international public, private, nonprofit, and for-profit organizations. These may include institutions of higher education, small businesses, independent school districts, local and state governments, and federally recognized tribal organizations. However, intramural Department of Defense organizations are ineligible to submit directly. Collaborative arrangements between extramural applicants and intramural investigators are permitted if properly documented. Proposals must not overlap with an organization’s fully funded internal programs, and all investigators must be affiliated with eligible institutions. Federally Funded Research and Development Centers (FFRDCs) are ineligible to apply directly but may participate as subrecipients if allowed by their sponsoring agreements. The opportunity does not specify a maximum or minimum award amount, nor does it place a limit on total program funding. Budgets should be appropriate for the scale and complexity of the research and include all direct and indirect costs. For assistance agreements, the performance period may extend up to four years, while for contracts, the period may be up to five years. Projects are expected to begin following the negotiation process, with clinical trials required to start within 12 months of award. Matching funds are not required unless proposing an award mechanism such as Other Transactions Authority (OTA), in which cost-sharing may apply. For further assistance, applicants may contact the eBRAP Help Desk at help@eBRAP.org or 301-682-5507, or the Grants.gov Contact Center at support@grants.gov or 800-518-4726. Comprehensive submission instructions are available in the BAA and its companion General Submission Instructions document. This BAA is continuously open until September 30, 2027, and recurring annually with amendments as needed. Applicants are encouraged to begin the submission process early and ensure compliance with all requirements to avoid disqualification.

Do not include proprietary information in pre-application. Strictly follow SOW and formatting guidelines.