FY25 Ensuring Research Integrity - Research on Research Integrity (RRI)

The FY25 Ensuring Research Integrity - Research on Research Integrity (RRI) grant opportunity, issued by the Office of the Assistant Secretary for Health within the U.S. Department of Health and Human Services (HHS), is administered through the Office of Research Integrity (ORI). This grant aligns with ORI’s mission to enhance research environments by fostering the responsible conduct of research (RCR) and addressing instances of research misconduct. The program is supported under the authority of Section 301 of the Public Health Service Act (42 U.S.C. § 241) and relevant regulatory frameworks including 42 C.F.R. § 93.300c and 42 C.F.R. Part 93. This grant opportunity is designed to support empirical research on the root causes of research misconduct and the factors that contribute to or inhibit research integrity. The primary objective of the RRI initiative is to investigate societal, organizational, behavioral, and individual influences that affect the integrity of research. By promoting a deeper understanding of the motivations and deterrents associated with research misconduct, ORI seeks to improve preventive strategies and foster a culture of ethical research practices at Public Health Service (PHS)-funded institutions. Eligible applicants for this opportunity include a broad range of entities: public and private institutions such as universities, hospitals, laboratories, and nonprofits (with or without 501(c)(3) status); governmental bodies including state, county, city, and special district governments; public and state-controlled as well as private institutions of higher education; Native American tribal governments (both federally recognized and otherwise), tribal organizations, and housing authorities; for-profit organizations, including small businesses and others; individuals; and faith-based and community-based organizations. This inclusive eligibility criterion underscores the federal commitment to engaging diverse stakeholders in safeguarding research integrity. The funding instrument type is a grant, and the opportunity is classified as discretionary under the Assistance Listing 93.085. The estimated total program funding is $500,000, with award ceilings set at $250,000 and award floors at $150,000. ORI anticipates making approximately two awards under this opportunity. Cost sharing or matching is not required. Funding is expected to cover projects that align with the core mission of promoting research integrity and understanding misconduct, with spending guided by federal grant management regulations. Applications for this opportunity opened on July 17, 2025, and the final deadline to submit is July 30, 2025. No preliminary or pre-application deadlines such as letters of intent were mentioned. The grant is not offered on a rolling basis, and there is no indication that it recurs annually or periodically. Therefore, it is critical that interested applicants complete submissions by the stated closing date. The primary contact for applicants encountering technical difficulties is the Grants.gov Contact Center, reachable at 1-800-518-4726. The contact center operates 24 hours a day, seven days a week, excluding federal holidays. Further information, including the full grant notice, can be found on the Grants.gov website under the opportunity number IR-ORI-25-004. No specific contact person or email address is listed for programmatic inquiries.