Quality of Life Grants Program
This grant provides funding to nonprofit organizations in the U.S. to support programs that improve the quality of life for individuals living with paralysis and their families.
The Christopher & Dana Reeve Foundationโs Quality of Life Grants Program is a long-standing initiative designed to enhance the lives of individuals living with paralysis and their families. Initiated by the late Dana Reeve, the program has awarded over $48 million to more than 4,000 projects since its inception in 1999. It operates under the umbrella of the National Paralysis Resource Center, a program funded entirely by the Administration for Community Living, U.S. Department of Health and Human Services, with a cooperative agreement valued at $10 million. The program provides financial support to nonprofit organizations and eligible institutions that deliver impactful services and projects for individuals living with paralysis. The grants aim to promote community engagement, accessibility, independence, and overall well-being through various categories, including assistive technology, employment, rural services, and caregiver support. Funding is not available for individuals, for-profit entities, fiscal sponsors, organizations based outside the U.S., or projects that fail to comply with federal guidelines, such as those involving rehabilitative therapy or major construction. The Quality of Life Grants are structured across five tiers. Direct Effect grants (Tier 1) range from $5,000 to $24,999 and are awarded biannually. Priority Impact grants (Tiers 2โ4) offer up to $30,000 for assistive technology, $40,000 for rural services, and $50,000 for employment and nursing home transitions; these grants are issued once per year in the second cycle. Expanded Impact (Tier 5) grants provide up to $100,000 and are reserved for prior grantees demonstrating strong outcomes and scalability. These are issued annually in the spring. All funded projects must be completed within 12 to 24 months, depending on the tier level. Eligibility is restricted to organizations with their own 501(c)(3) status or government and tribal entities. Fiscal sponsors are explicitly excluded. The foundation prioritizes initiatives that serve veterans and under-resourced communities, including rural populations, people at risk of incarceration, non-majority racial groups, and others. Each applicant may only apply once per cycle, and grantees are limited to one award in a given category during the current cooperative agreement period (2021โ2026), except in cases where they apply for a different tier or category. Applications are accepted through an online portal, and applicants are encouraged to review the Program Overview and Eligibility Criteria thoroughly. The current funding cycle (2nd Cycle 2025) is open for Direct Effect and Priority Impact tiers. The deadline for submissions is Tuesday, October 7, 2025, at 11:59 PM. Awards will be announced by December 31, 2025. The program is expected to continue on a recurring annual basis, with the next cycle likely to begin in early 2026. For further inquiries, applicants can reach the foundation at QOL@Reeve.org or call 1-800-225-0292.
Award Range
$5,000 - $50,000
Total Program Funding
$10,000,000
Number of Awards
Not specified
Matching Requirement
No
Additional Details
The program supports five grant tiers ranging from $5,000 to $100,000, with specific focus areas such as assistive technology, rural services, employment, and caregiver support. Each tier has its own criteria and duration, from 12 to 24 months. Certain expenses such as capital improvements, food, and direct payments to individuals are prohibited.
Eligible Applicants
Additional Requirements
Eligible entities include 501(c)(3) nonprofit organizations, tribal entities, municipal and state governments, school districts, and institutions such as veterans and community hospitals. Fiscal sponsors are not permitted. Applicants must serve individuals with paralysis. Organizations may not receive more than one grant in the same category between 2021 and 2026.
Geographic Eligibility
All
Review the Program and Application Guidelines for your specific cycle. Adhere to funding category restrictions and timelines. Note ineligibility for repeat grants in same category through June 30, 2026.
Application Opens
August 14, 2025
Application Closes
October 7, 2025
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