Community Based Participatory Research To Advance DAta and Practice Transformation (ADAPT) For Optimizing Oral Health For All Across the Lifespan (UG3/UH3 Clinical Trial Optional)

The National Institutes of Health (NIH), through its National Institute of Dental and Craniofacial Research (NIDCR), has issued a forecasted funding opportunity titled "Community Based Participatory Research To Advance DAta and Practice Transformation (ADAPT) For Optimizing Oral Health For All Across the Lifespan (UG3/UH3 Clinical Trial Optional)." This funding initiative aims to promote the integration of services, systems, and values through population-based interventions that address oral health disparities across communities in the United States. The grant mechanism will be a cooperative agreement using the UG3/UH3 activity code, with a focus on collaborative, multisectoral research aimed at transforming both practice and data utilization for improved oral health outcomes. The ADAPT initiative encourages applicants to evaluate, implement, or test interventions that leverage cross-sector partnerships within communities. These interventions must focus on social and chronic disease risk factors and barriers that contribute to oral health burdens, particularly in underserved populations. The funded projects will be integrated into a larger Community-Based Participatory Research (CBPR) Consortium and supported by a separately funded Community Engagement Evaluation and Data Coordination hub (CEED). Additionally, awardees will receive consultative services from the NIH Community Engagement Alliance Consultative Resource (CEACR) and collaborate through the Science Collaborative for Health disparities and Artificial intelligence Reduction of Errors (SCHARE) platform. Funding is being provided under the federal assistance listing 93.121 for Oral Diseases and Disorders Research. The opportunity is discretionary in nature and will operate as a cooperative agreement. Although the estimated total program funding, award ceiling, and award floor are not specified at this stage, the estimated number of awards has not yet been determined. The NIH has forecasted the funding opportunity on May 12, 2025, with an estimated posting date of July 3, 2025. Applications will be due by October 7, 2025, and awards are anticipated to be made by July 1, 2026, which also marks the expected project start date. Eligible applicants include a broad array of entities such as state and county governments, public and private institutions of higher education, public housing authorities, tribal governments and organizations, independent school districts, small businesses, and certain nonprofit organizations. Notably, both federally recognized and non-federally recognized tribal entities are eligible to apply. The eligibility extends nationwide without geographic restrictions, and there is no matching or cost-sharing requirement for applicants. Currently, applications are not being accepted, as this is a forecasted opportunity. NIH has issued this notice in advance to provide interested applicants sufficient time to establish meaningful collaborations and develop proposals responsive to the scope and objectives of the funding. Investigators with expertise in population-based interventions and community-partnered research are particularly encouraged to consider engaging with this opportunity. For questions or more information, the grant contact is Hiroko Iida, DDS, MPH, at the National Institute of Dental & Craniofacial Research. She can be reached by phone at 301-594-7404 or via email at hiroko.iida@nih.gov.