The Centers for Disease Control and Prevention (CDC), operating under the U.S. Department of Health and Human Services, is forecasting a cooperative agreement opportunity focused on strengthening and modernizing public health systems in Uganda. This initiative is aligned with the President’s Emergency Plan for AIDS Relief (PEPFAR) and targets enhancements in data science, informatics, implementation science, survey and surveillance capacity. The primary goal is to support the Ugandan Ministry of Health’s digital transformation strategy, enabling more effective epidemic intelligence and decision-making in HIV and related health programs.
This funding opportunity will support the development of a modernized data ecosystem encompassing a variety of systems. These include electronic medical records, digital registers, disease and clinical surveillance, laboratory information systems, logistics and pharmacy management, community-level data collection, and human resource systems. A critical component will be addressing existing data and knowledge gaps through targeted surveys and implementation science activities.
Grantees will also be expected to contribute to the development and integration of digital health solutions such as data warehousing and interoperability mechanisms. These systems must support sustainability, functionality, and a comprehensive digital infrastructure across Uganda’s public health landscape. The focus will be on building enduring capacities that empower local institutions to manage and utilize data for prompt and effective action.
The funding instrument is a cooperative agreement, indicating significant CDC involvement in the project’s execution. While the award ceiling for Year 1 is stated as zero, the CDC anticipates approximately $30 million in total fiscal year funding for that year, contingent on appropriations. The opportunity is classified under CFDA 93.067, indicating its alignment with global AIDS funding streams.
Eligible applicants include a broad array of U.S.-based and international entities such as state and local governments, higher education institutions, tribal organizations, nonprofits, and for-profit businesses. There is no cost-sharing or matching requirement for this opportunity. Proposals must be submitted electronically by March 13, 2026, at 11:59 PM ET, with an anticipated award and project start date of September 30, 2026.
The forecasted date of announcement is December 2, 2025. Interested parties may direct inquiries to the CDC's DGHT NOFOs office at pepfarfoas@cdc.gov. Though this is a forecast and subject to change, organizations interested in global health systems development and digital innovation should begin preparing in anticipation of the formal Notice of Funding Opportunity.
