The Centers for Disease Control and Prevention (CDC), under the U.S. Department of Health and Human Services, has issued a forecasted opportunity to strengthen technical assistance and capacity building for public health care services in the Republic of Mozambique under the President’s Emergency Plan for AIDS Relief (PEPFAR). This program continues the longstanding collaboration between the United States and Mozambique to combat HIV/AIDS and tuberculosis by reinforcing national and provincial health systems, ensuring that gains in disease control are sustainable through increased local capacity and improved program efficiency.
The initiative aims to provide technical support to Mozambique’s Ministry of Health to expand the reach and quality of HIV and TB prevention, care, and treatment services. Funding will support national-level activities such as guideline and policy development, training curricula design, training of trainers, and experience-sharing mechanisms. These activities are expected to foster documentation and replication of evidence-based, innovative practices that enhance program effectiveness and promote the integration of TB and HIV services within the broader health system.
At the provincial level, awardees will provide targeted technical assistance to strengthen administrative, managerial, and financial systems. This includes specialized financial management support, the implementation of partner-to-government transition models, and coordination with local directorates of health to ensure equitable distribution of resources and improved data-driven decision making. The cooperative agreement mechanism reflects CDC’s intention to maintain substantial involvement, providing ongoing consultation, technical direction, and oversight throughout project implementation.
CDC anticipates making up to two awards under this opportunity, subject to the availability of funds, with approximately $15 million expected in total program funding for the first year. Cost sharing or matching is not required. Eligible applicants include a wide range of entities such as state and local governments, tribal organizations, educational institutions, nonprofits (with or without 501(c)(3) status), and for-profit organizations. International organizations are eligible as noted under unrestricted eligibility, provided they can meet the capacity and compliance requirements set forth by CDC.
The anticipated publication date for this funding announcement is December 2 2025, with full applications due by February 17 2026 at 11:59 p.m. ET. Awards are expected to be issued by September 30 2026, with projects beginning the same day. Applications must be submitted electronically through Grants.gov. Technical questions should be directed to the CDC PEPFAR Funding Opportunities team via pepfarfoas@cdc.gov. As a forecasted notice, all details remain subject to change pending final release of the Notice of Funding Opportunity.
Emphasize capacity building and sustainability; demonstrate HIV/TB program experience and coordination with Mozambique MOH
