Implement and sustain a comprehensive response to HIV and technical assistance to strengthen the capacity of regional authorities in the United Republic of Tanzania under PEPFAR

The Centers for Disease Control and Prevention (CDC), operating under the U.S. Department of Health and Human Services, is forecasting a cooperative agreement opportunity aimed at implementing and sustaining a comprehensive response to HIV and tuberculosis in the United Republic of Tanzania. This initiative aligns with the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) and seeks to strengthen the capacity of regional authorities to manage, deliver, and sustain high-quality HIV/TB prevention, care, and treatment services. With an anticipated total fiscal year funding of approximately $35 million in Year 1, this opportunity will support transformative partnerships that enhance local governance, improve service delivery models, and ensure data-driven program management to achieve national and global HIV epidemic control goals. The program’s objectives are designed to advance Tanzania’s progress toward the UNAIDS 95-95-95 targets by improving health outcomes and expanding the reach of integrated HIV/TB services. Recipients will provide technical assistance to regional and local health authorities, ensuring sustainability through strengthened administrative and operational capacity. Funded activities will include the adaptation and use of monitoring and evaluation tools to identify service gaps, enhance coordination across stakeholders, and promote evidence-based interventions that improve efficiency and patient outcomes. This opportunity emphasizes health system strengthening and long-term capacity building. It prioritizes efficient data management, improved reporting mechanisms, and sustainable funding models for health facilities. Collaborative efforts among regional partners will ensure harmonized approaches to HIV/TB program implementation, capacity enhancement for local government agencies, and reinforcement of accountability systems for continued program success. The cooperative agreement model will allow CDC to provide direct technical and programmatic oversight while enabling awardees to leverage local expertise and partnerships. Eligible applicants include a wide range of entities such as state and local governments, Native American tribal governments and organizations, independent school districts, nonprofit and for-profit organizations, higher education institutions (both public and private), and public housing authorities. International eligibility extends to Tanzanian entities collaborating with local and regional partners. No cost sharing or matching requirement applies to this opportunity. The anticipated number of awards is three, with an estimated project start date of September 30, 2026. Applications will be submitted electronically through Grants.gov by February 17, 2026, no later than 11:59 p.m. Eastern Time. The forecasted posting date for the full Notice of Funding Opportunity (NOFO) is December 2, 2025. Interested applicants should monitor Grants.gov for updates and detailed instructions once the NOFO is released. For inquiries or technical assistance, applicants may contact the CDC’s Division of Global HIV & TB (DGHT) via the official inbox at [email protected]. This funding opportunity represents a critical investment in global health security and disease control infrastructure to sustain the fight against HIV and TB in Tanzania.