HIV/AIDS Clinical Trials Network Statistical and Data Management Centers

The HIV/AIDS Clinical Trials Network Statistical and Data Management Centers opportunity is forecasted by the National Institutes of Health within the U.S. Department of Health and Human Services, specifically through the National Institute of Allergy and Infectious Diseases. This initiative is part of a broader federal effort to advance research aimed at ending the HIV epidemic. The program is structured to support the infrastructure of four Clinical Trials Networks, each composed of a Leadership and Operations Center, a Statistical and Data Management Center, and a Laboratory Center working collaboratively with Clinical Trials Units. The Statistical and Data Management Centers play a central coordinating and analytical role within these networks. The primary purpose of this funding opportunity is to establish and support up to four Statistical and Data Management Centers that will guide the design, execution, and analysis of clinical trials related to HIV and associated diseases. These centers are responsible for ensuring high-quality data collection, management, and integration across multiple clinical sites and laboratories. The funding supports activities such as statistical leadership, protocol development, innovative trial design, and harmonization of data standards and methodologies across the network. Funding will be provided through cooperative agreements, indicating substantial federal involvement in programmatic activities. While specific funding amounts, ceilings, and floors are not disclosed in the forecast, the scope of work suggests large-scale, multi-year infrastructure and research coordination investments. Allowable uses of funds include personnel, systems for data capture and integration, statistical analysis tools, and compliance systems aligned with NIH data sharing policies. There is no cost-sharing or matching requirement associated with this opportunity. Eligibility for this opportunity is broad and inclusive, encompassing a wide range of public, private, nonprofit, and governmental entities. Eligible applicants include institutions of higher education (both public and private), nonprofits with or without 501(c)(3) status, for-profit organizations, small businesses, state and local governments, tribal governments and organizations, public housing authorities, and other regional or community-based organizations. Federal agencies and U.S. territories are also eligible, reflecting the national scope and collaborative intent of the program. The application process is expected to follow NIH submission protocols, likely involving electronic submission through Grants.gov and associated systems. While specific application components are not detailed in the forecast, applicants can anticipate requirements such as research strategy narratives, data management plans, organizational capacity descriptions, and compliance documentation. Evaluation criteria will likely focus on scientific merit, organizational capability, data management expertise, and alignment with NIH priorities. Key dates indicate that the opportunity is currently in a forecast stage, with an estimated posting date of August 25, 2026, and an anticipated application due date of January 22, 2027. Awards are expected to be issued by December 1, 2027, with project start dates aligned to that same day. The opportunity appears to follow a structured federal grant cycle, though recurrence is not explicitly stated. Interested applicants are encouraged to monitor updates and prepare early given the complexity and scale of the program. For additional information, applicants may contact the Division of AIDS at the National Institute of Allergy and Infectious Diseases via the provided email address. This forecast is authorized under sections of the Public Health Service Act and relevant federal regulations, reinforcing its legitimacy and alignment with national public health research priorities.