Limited Competition: NIGMS Mature Synchrotron Resources for Structural Biology

The National Institute of General Medical Sciences (NIGMS), a division of the National Institutes of Health (NIH), is announcing a forecasted funding opportunity for the support of mature synchrotron resources critical to the field of structural biology. This limited competition grant is intended to maintain and enhance national access to advanced synchrotron technologies that provide cutting-edge X-ray beamlines, hands-on user training, and technical support for biomedical researchers working with structural biology data. This funding opportunity targets synchrotron resources that are currently or were recently funded by NIGMS, ensuring continuity of services and infrastructure essential to the biomedical research community. The aim is to enable researchers to access high-performance X-ray beamlines and associated analytical tools, furthering discoveries in molecular and cellular structures that underpin human health and disease. As a limited competition, the program is open only to synchrotron resources with current or recent NIGMS support; resources whose funding ended more than 36 months prior to the application due date are not eligible. The funding will support both operations and development of the beamlines, as well as outreach and training for users across the U.S., enhancing equity of access and fostering scientific collaboration. There is no matching or cost-sharing requirement for this grant. While specific funding amounts and number of awards have not been disclosed in the forecast, applicants should be aware that the opportunity falls under Assistance Listing 93.859 – Biomedical Research and Research Training. The application process will follow standard NIH peer review procedures, with scientific merit being the primary basis for funding decisions. The estimated posting date is August 13, 2026, and applications will be due by October 13, 2026. Awards are expected to be issued by July 1, 2027, which will also be the start date of the funded projects. Interested parties should prepare to submit full applications through Grants.gov and ensure compliance with NIH submission procedures and eligibility criteria. Program-specific inquiries should be directed to the official program inbox at [email protected]. This forecasted opportunity is expected to recur and continues NIH’s commitment to sustaining high-quality structural biology infrastructure at synchrotron facilities.