Notice of Intent to Publish a Funding Opportunity Announcement for Diabetes Research Centers (P30 Clinical Trial Optional)

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the U.S. Department of Health and Human Services through the National Institutes of Health (NIH), intends to issue a Notice of Funding Opportunity (NOFO) for Diabetes Research Centers (DRCs). This planned funding initiative aims to foster a community of researchers focused on diabetes and related endocrine and metabolic disorders. The overarching goal is to advance research and improve health outcomes for individuals with diabetes in the United States. This notice is currently a forecast, meaning formal applications are not yet being solicited. The DRCs are intended to strengthen existing research by promoting communication, multidisciplinary collaboration, and mentoring among clinical and preclinical diabetes investigators. Key components of the Centers include an enrichment program, access to shared technical resources through biomedical research cores, and a Pilot and Feasibility Program (P&F). These elements are designed to enhance the collective impact of diabetes research efforts beyond what individual grants might achieve alone. A significant emphasis is placed on proposals that introduce unique scientific themes or innovative resources, particularly in emerging scientific areas with the potential to improve metabolic health. Proposals that create synergy with other NIH and NIDDK resources and foster a robust mentoring environment for new researchers are especially encouraged. Collaboration across disciplines such as Immunology, Endocrinology, Metabolism, Endotyping, and Artificial Intelligence is also a focus, and potential applicants in these areas should begin planning their applications. The funding opportunity will utilize the P30 activity code, and while applications are not currently being accepted, this advance notice is intended to give researchers ample time to develop collaborations and responsive projects. The estimated post date for the formal NOFO is July 30, 2025, with an application due date set for March 11, 2026. Awards are expected to be announced by December 30, 2026, which is also the projected start date for funded projects. Eligibility for this opportunity is broad and includes a wide range of governmental and non-governmental entities. These include tribal governments, nonprofits (with and without 501(c)(3) status), educational institutions, public housing authorities, for-profit organizations, and other eligible federal and non-U.S. entities. Special emphasis is placed on inclusive eligibility to encourage diverse and collaborative applications. For further details or questions, interested parties are advised to contact Dr. Christopher J. Lynch at the National Institute of Diabetes and Digestive and Kidney Diseases via email at lynchcj@nih.gov or phone at 301-325-4232.