Biosensing
This grant supports innovative engineering research that develops advanced biosensing technologies for monitoring biological substances, with applications in health, environmental protection, and public safety.
The Biosensing program is part of the Engineering Biology and Health cluster, which also includes 1) the Biophotonics program; 2) the Cellular and Biochemical Engineering program; 3) the Disability and Rehabilitation Engineering program; and 4) the Engineering of Biomedical Systems program. The Biosensing program supports fundamental engineering research in the monitoring, identification and/or quantification of biological analytes and phenomena using innovations that exist at the intersection of engineering, life sciences, and information technology. Projects submitted to the program must advance both engineering and life sciences. The Biosensing program encourages proposals that, in addition to advancing biosensing technology, address critical sensor needs in biomedical research, public health, food safety, agriculture, forensics, environmental protection, and homeland security. Proposals are especially encouraged in areas of critical need: sensing technologies that can enable monitoring and surveillance of the environment and/or individuals for novel infectious agents; platform technologies that can readily be modified as soon as new agents are detected, sequenced, and/or otherwise characterized to enable rapid deployment of sensors in clinics and the environment; and adaptive and/or multiplex sensing technologies that can help the nation prevent the spread of the next global pandemic. Major areas of interest for the program include: Novel signal transduction principles and mechanisms that enable sensitive and specific biosensors, suitable for measurements in multiple areas; Design of novel biorecognition elements and appropriately designed transducing systems to enable adaptable and/or reconfigurable operating parameters in response to environmental changes or application needs at levels of device, system, or data analysis; Development of adaptive and/or evolvable biosensing systems for detection of novel target analytes or analytes under novel conditions; Novel synthetic biology approaches for the development of cell-free and cell-based biosensors; and Combining biosensors with artificial intelligence (AI) methods to improve sensor specificity and response time. Innovative ideas outside of the above specific interest areas may be considered. However, prior to submission, it is recommended that the PI contact the program director to avoid the possibility of the proposal being returned without review. The Biosensors program does not encourage proposals addressing circuit design for signal processing and amplification, computational modeling, and microfluidics for sample separation and filtration. Medical imaging-based measurements are outside of the scope of the program interests. Proposals that rely heavily on descriptive approaches are given lower priority. Proposals for optimizing and/or utilizing established methods for specific applications should be directed to programs focused on the application of sensor technology. NOTE: Projects related to water and/or soil quality may be jointly supported with the Environmental Engineering program (CBET 1440). Photonic devices with medical imaging and/or optogenetics should be submitted to the Biophotonics program (CBET 7236). Applications of devices for tissue engineering or organ-on-chip systems should be submitted to the Engineering of Biomedical Systems program (CBET 5345). Basic chemical/biochemical sensing mechanisms should be submitted to the Chemical Measurement and Imaging program (CMI 6880) in the Division of Chemistry. Proposals for dynamic biosensing systems, including circuit design for signal/data processing and amplification, and sensing systems through communication and machine learning should be submitted to the Communications, Circuits, and Sensing-Systems program (CCSS 7564) in the Division of Electrical, Communications, and Cyber Systems. INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/orpotentially transformative natureof the proposed work compared to previous work in the field.Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research.The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal. The duration of unsolicited proposal awards in CBET is generally up to three years. Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year(awards for multiple investigator projects are typically larger). Proposal budgets that are much larger than typical should be discussed with the program director prior to submission. Proposers can view budget amounts and other information from recent awards made by this program via the ?What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)? link towards the bottom of this page. Faculty Early Career Development(CAREER)program proposals are strongly encouraged.Award duration is five years.The submission deadline for Engineering CAREER proposals is in July every year. Learn more in the CAREER program description. Proposals for Conferences, Workshops, and Supplements: PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal. Grants forRapid Response Research(RAPID)andEArly-concept Grants for Exploratory Research(EAGER)are also considered when appropriate. Please note that proposals of these types must be discussed with the program director before submission. Grant Opportunities for Academic Liaison with Industry (GOALI)proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged. Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year. Details about RAPID, EAGER, and GOALI are available in the Proposal Award Policies Procedures Guide(PAPPG), Part 1, Chapter II, Section E: Types of Proposals. Compliance: Proposals that are not compliant with theProposal Award Policies Procedures Guide (PAPPG)will be returned without review.
Award Range
Not specified - Not specified
Total Program Funding
$7,600,000
Number of Awards
Not specified
Matching Requirement
No
Eligible Applicants
Additional Requirements
NSF welcomes proposals on behalf of all qualified scientists, engineers, and educators. The Foundation strongly encourages women, minorities, and persons with disabilities to participate fully in its programs. In accordance with Federal statutes, regulations and NSF policies, no person on grounds of race, color, age, sex, national origin, or disability shall be excluded from participation in, be denied the benefits of, or be subjected to discrimination under, any program or activity receiving financial assistance from NSF, although some programs may have special requirements that limit eligibility. Scientists, engineers, and educators usually initiate proposals that are officially submitted by their employing organization. Before formal submission, the proposal may be discussed with appropriate NSF program staff. Graduate students are not encouraged to submit research proposals but should arrange to serve as research assistants to faculty members. Some NSF divisions accept proposals for Doctoral Dissertation Research Grants when submitted by a faculty member on behalf of the graduate student. Categories of Proposers – The following describes the eligibility of specific categories of proposers. A program solicitation, however, may apply more restrictive eligibility criteria. 1. The following organizations are eligible to submit proposals to NSF: (a) Institutions of Higher Education (IHEs) Two- and four-year IHEs (including community colleges) accredited in, and having a campus located in the U.S., acting on behalf of their faculty members. IHEs located outside the U.S. fall under paragraph 2(c) below. Special Instructions for International Branch Campuses of U.S. IHEs If the proposal includes funding to be provided to an international branch campus of a U.S. IHE (including through use of subawards and consultant arrangements), the proposer must explain the benefit(s) to the project of performance at the international branch campus and justify why the project activities cannot be Proposal & Award Policies & Procedures Guide I-6 NSF 24-1 performed at the U.S. campus. Such information must be included in the project description. The box for “Funding of an International Branch Campus of a U.S. IHE” must be checked on the Cover Sheet if the proposal includes funding for an international branch campus of a U.S. IHE. (b) Non-profit, Non-academic Organizations Independent museums, observatories, research laboratories, professional societies, and similar organizations located in the U.S. that are directly associated with educational or research activities. (c) Tribal Nations The term “Tribal nation” means an American Indian or Alaska Native tribe, band, nation, pueblo, village, or community that the Secretary of the Interior acknowledges as a federally recognized tribe pursuant to the Federally Recognized Indian Tribe List Act of 1994, 25 U.S.C. §§ 5130- 5131. 2. The following organizations may be eligible to submit proposals to NSF: (a) For-profit Organizations U.S.-based commercial organizations, including small businesses, with strong capabilities in scientific or engineering research or education and a passion for innovation. An unsolicited proposal from a for-profit organization may be funded when the project is of special concern from a national point of view, special resources are available for the work, or the proposed project is especially meritorious. NSF is interested in supporting projects that couple industrial use-inspired challenges and research resources with those of IHEs; therefore, the Foundation especially welcomes proposals for cooperative projects involving both IHEs and industry. Specific NSF funding opportunities also may make for-profit organizations eligible for submission of proposals to the Foundation. US-based affiliates or subsidiaries of foreign organizations must contact the cognizant NSF program officer prior to preparing and submitting a proposal to NSF. (b) State and Local Governments As programmatically necessary and as provided for in a solicitation, State and local governments may be eligible to submit proposals. (c) Foreign Organizations — NSF rarely provides direct funding support to foreign organizations. NSF will consider proposals for cooperative projects involving U.S. and foreign organizations, provided support is requested only for the U.S. portion of the collaborative effort. In cases however, where the proposer considers the foreign organization or foreign individual’s involvement to be essential to the project and proposes to provide funding through the NSF budget (via a subaward or consultant arrangement), the proposer must justify the benefit to U.S. research and education. The justification must include, at minimum: • why support from the foreign counterpart’s in-country resources is not feasible; • why the foreign organization or foreign individual can carry out the activity more effectively than a U.S. organization or U.S. individual; • what unique expertise, organizational capability, facilities, data resources, and/or access to a geographic location not generally available to U.S. investigators the foreign organization or foreign individual brings to the project; and • what significant science and engineering education, training, or research opportunities the foreign organization or foreign individual offers to the U.S. Such information must be included in any proposal to NSF, including new and renewal proposals. The information must be included in the project description section of the proposal. The box for "Funding of a Foreign Organization or Foreign Individual" must be checked on the Cover Sheet if the proposal includes funding for a foreign organization or foreign individual.
Geographic Eligibility
All
Application Opens
September 12, 2019
Application Closes
Not specified
Grantor
NSF grants.gov support
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