PRIMED-AI: Logistics Center (U24 Clinical Trial Not Allowed)

The National Institutes of Health (NIH), through its Common Fund and other collaborating NIH Institutes and Centers (ICs), is preparing to release a Notice of Funding Opportunity (NOFO) under the program title "PRIMED-AI: Logistics Center." This grant opportunity, identified by opportunity number NOT-RM-25-026, falls under the U24 Cooperative Agreement mechanism and does not allow for clinical trials. This initiative is currently in the forecast stage, with an expected post date of July 1, 2025. The funding is expected to support projects beginning on or after September 1, 2026, with applications due by November 1, 2025. The PRIMED-AI program—Precision Medicine with Artificial Intelligence: Integrating Imaging with Multimodal Data—seeks to support the development of advanced AI tools that can seamlessly integrate clinical imaging data with other types of health data. The overarching goal is to enhance the practice of personalized medicine, particularly for individuals with chronic or complex medical conditions. This forecasted NOFO specifically focuses on establishing a Logistics Center to manage and coordinate key administrative and strategic activities within the program’s research consortium. The Logistics Center will be structured around three interdependent cores: Administration, Evaluation, and Outreach. These cores will collectively oversee the management of consortium governance structures, facilitate communication across program stakeholders, organize community engagement events such as workshops and code-a-thons, and support strategic outreach and teaming activities. The center is intended to play a pivotal role in ensuring programmatic coherence and maximizing the overall impact of the PRIMED-AI initiative. Potential applicants with expertise in managing large-scale research consortia, administrative infrastructure, and health data systems are encouraged to prepare proposals that align with these aims. The estimated total program funding available under this opportunity is $2,750,000, though the maximum and minimum amounts per award have not been specified. Matching funds are not required. This opportunity is classified as discretionary funding in the health category under Assistance Listing 93.310 (Trans-NIH Research Support). Eligibility for this opportunity is broad and includes state and local governments, tribal governments and organizations (both federally recognized and not), housing authorities, public and private institutions of higher education, small businesses, for-profit organizations, and qualifying nonprofit entities. This broad eligibility framework reflects NIH’s interest in facilitating collaborative and multidisciplinary approaches to research and logistics management. Interested parties are advised that this is a forecasted opportunity and that applications are not currently being accepted. The advance notice is intended to allow ample time for institutions to build collaborative teams and prepare high-quality proposals responsive to the anticipated NOFO. The official agency contact for this opportunity is Dr. Sahana N. Kukke of the NIH Office of the Director. She can be reached by phone at 301-402-3756 or by email at ODPRIMED-AI@od.nih.gov. The NOFO is expected to be released on July 1, 2025, with a closing date for applications on November 1, 2025, and awards made by September 1, 2026.