Extension of the World Trade Center Health Registry (U50)

The Extension of the World Trade Center Health Registry (U50) is a forecasted funding opportunity offered by the Centers for Disease Control and Prevention under the U.S. Department of Health and Human Services. The Registry was originally established in 2002 through the collaboration of the Agency for Toxic Substances and Disease Registry and the New York City Department of Health to monitor the health of individuals directly exposed to the September 11, 2001, World Trade Center disaster. This initiative continues under the mandate of the James Zadroga 9/11 Health and Compensation Act and is designed to ensure the continuation of a centralized, scientifically rigorous health monitoring system for those impacted. The Registry serves as an ongoing resource for collecting and analyzing data to assess the long-term physical and mental health consequences of 9/11 exposure. It provides a unified database that supports public health research, healthcare policy development, disaster preparedness, and mental health support planning. Its work includes disseminating findings and recommendations to Registry enrollees, policymakers, healthcare providers, the public, and the broader scientific community. These findings inform both clinical care for survivors and emergency response strategies for future public health crises. Funding for this opportunity will be distributed through a cooperative agreement, emphasizing close collaboration between the recipient organization and the CDC. The total program funding is estimated at $44,000,000, with an award ceiling of $8,800,000. Only one award is anticipated. Funds are expected to cover continued operations of the Registry, including data collection, analysis, reporting, outreach, and communication with enrollees and stakeholders. No cost-sharing or matching funds are required. Eligibility for this opportunity is broad, extending to a wide range of entities including state and local governments, tribal governments and organizations, public and private institutions of higher education, nonprofits with or without 501(c)(3) status, public housing authorities, for-profit organizations, small businesses, and special district governments. Foreign institutions and non-domestic entities, including non-U.S. components of U.S. organizations, are explicitly ineligible. The estimated application open date is November 12, 2025, with applications due by January 12, 2026, no later than 5:00 p.m. local time of the applicant’s organization. The award announcement is expected on June 1, 2026, with projects beginning July 1, 2026. This funding opportunity is forecasted, meaning it is not yet open but is expected to be formally released on the estimated post date. Applications must be submitted electronically through Grants.gov by the due date. The primary contact for this opportunity is Dr. Eduardo O’Neill, Scientific Program Official at the CDC. He can be reached at 404-718-8844 or via email at fzt4@cdc.gov for questions regarding the scientific program or application process. As this is a forecast, applicants are advised to monitor Grants.gov for updates to the posting and final announcement details.