Targeting Inflammasomes in HIV and Substance Use (R01 Clinical Trial Not Allowed)

This funding opportunity supports research aimed at understanding how inflammasomes contribute to neurocognitive disorders and immune function in individuals with HIV and substance use disorders, encouraging innovative studies that link these areas to improve health outcomes.

$500,000

Closed

Nationwide

Grant Description

The scientific objective of this Notice of Funding Opportunity is to encourage research to delineate the role of inflammasomes in the neuropathology produced by acute or chronic drug exposure and HIV infection. Understanding the involvement of inflammasomes in virus and drug-induced immune activation may help identify molecular markers and CNS immune cells associated with HIV-1 infection or disease progression among substance abuse populations, as well as identify novel therapies to target inflammasome activation or suppression to treat neuroinflammation and immune dysregulation aroused in these processes.

Funding Details

Award Range

Not specified - $500,000

Total Program Funding

Not specified

Number of Awards

Not specified

Matching Requirement

Eligibility

Eligible Applicants

State governments

County governments

City or township governments

Special district governments

Independent school districts

Additional Requirements

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Geographic Eligibility

All

Key Dates

Application Opens

October 17, 2023

Application Closes

October 28, 2024

Contact Information

Grantor

U.S. Department of Health & Human Services (National Institutes of Health)

grantsinfo@nih.gov

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