Pfizer’s Sickle Cell Advocacy & Leadership Empowerment (SCALE) Grants initiative is a competitive funding program designed to support innovative health solutions that address persistent challenges in care access and policy change for individuals living with Sickle Cell Disease (SCD). Despite affecting over 100,000 individuals in the United States, SCD remains underfunded and misunderstood. The SCALE Grants seek to enable grassroots, nonprofit, and advocacy organizations to propose projects that improve health equity and help accelerate the development of impactful health policy for the SCD community.
Eligible applicants must align their proposals with at least one of three grant categories: Assessment & Analysis, Policy & Advocacy, or Data Collection/Surveillance. Funded projects may include pilot programs, community outreach initiatives, policy advocacy efforts, rural health equity models, or surveillance mechanisms to generate data for decision-making. Programs must have measurable outcomes, demonstrate policy relevance, and be capable of advancing advocacy goals. Emphasis is placed on underserved and rural populations and the reduction of health disparities in SCD treatment.
The program will distribute a total of $150,000 in accelerator funding, with the amount of each grant based on the needs of the proposed project. Pfizer does not permit the requested amount to exceed 50% of the applying organization’s annual operating budget. Proposals must outline how the work will impact policy and specify evaluation metrics, project timelines, and dissemination strategies.
Applications open on September 15, 2025, and must be submitted by October 15, 2025. All applications must be submitted via Pfizer’s CyberGrants portal and follow the provided application template, which includes sections on project design, innovation, target audiences, outcomes, and alignment with public policy goals.
For inquiries, applicants should use the contacts provided within the CyberGrants system.
Ensure strong alignment with one or more categories and provide a clear policy impact path. Budget requests must reflect organizational scale and policy relevance.
