Hereditary Hemorrhagic Telangiectasia (HHT) Center

The Hereditary Hemorrhagic Telangiectasia (HHT) Center Program is a new cooperative agreement opportunity announced by the Health Resources and Services Administration (HRSA), an agency within the U.S. Department of Health and Human Services. HRSA leads public health efforts to improve access to health care services for people who are uninsured, isolated, or medically vulnerable. This forecasted funding opportunity reflects HRSA’s ongoing commitment to rare disease intervention and care coordination at the national level. The primary objective of this grant is to reduce illness and death associated with Hereditary Hemorrhagic Telangiectasia (HHT), a rare genetic disorder that affects blood vessels and can lead to serious complications such as bleeding and organ damage. Through this program, HRSA seeks to partner with a clinical center that can expand access to diagnosis and treatment while also improving the quality and coordination of care for patients affected by HHT. This includes development of innovative strategies to support clinicians in identifying and diagnosing HHT cases more effectively. A significant component of the grant includes the establishment of a de-identified, aggregate patient data registry. The registry is intended to enhance the broader medical community’s understanding of HHT and its treatment outcomes. The data collected will support both clinical research and the development of future care protocols, ensuring a data-driven approach to improving patient health outcomes over time. The funding will be administered as a cooperative agreement, indicating substantial involvement by HRSA throughout the project period. One award is expected to be made, with an estimated total program funding of $2.9 million. The same amount serves as the award ceiling, while no minimum floor has been specified. No cost sharing or matching is required for applicants. Eligible applicants include a broad range of domestic organizations, including state, county, and city governments; Native American tribal governments and organizations; independent school districts; public and private institutions of higher education; and nonprofits both with and without 501(c)(3) status. Additionally, community-based organizations that meet any of these criteria are also eligible. Eligibility is limited to domestic entities operating within the U.S. and specified territories. The estimated posting date for the full application materials is May 8, 2026, with applications due by June 23, 2026, at 11:59 p.m. Eastern Time. The anticipated award date is August 2, 2026, with a project start date of September 1, 2026. As of this forecast release, there is no indication of pre-application requirements such as a letter of intent or concept paper. For further inquiries, applicants are directed to contact Nordia Williams at 240-475-3310 or via email at [email protected].