The U.S. Department of State, Bureau of Oceans and International Environmental and Scientific Affairs Office of Conservation, and Water (OES) announces the Notice of Funding Opportunity (NOFO) for a program to help address and identify solutions to shared water challenges in the Mekong sub-region by developing and hosting the 4th Mekong Research Symposium (MRS), under the Mekong-U.S. Partnership (MUSP). The MRS will convene stakeholders (including academia, private sector, media and journalists, local government, donors, development and financing partners, non-profits, civil society organizations, and indigenous communities) to present on advancements in science and technology, including local solutions, and raise awareness of existing initiatives and resources to provide long-term, equitable benefits across the sub-region.