Deciphering the Impact of RNA Modifications on Brain Aging and AD/ADRD (R01 Clinical Trial Not Allowed)

This funding opportunity is designed for researchers investigating how RNA modifications affect brain aging and the development of Alzheimer's disease and related dementias, with the goal of discovering new biomarkers and drug targets.

$125,000

Closed

Nationwide

Grant Description

The purpose of this Notice of Funding Opportunity (NOFO) is to catalyze innovative research to elucidate the molecular landscape and functional implications of RNA modifications in brain aging and Alzheimer's disease (AD) and AD-related dementias (ADRD). AD-related dementias include Lewy body dementia (LBD), frontotemporal dementia (FTD), vascular cognitive impairment/dementia (VCI/D), and mixed dementias. This NOFO supports applications focused on uncovering novel mechanisms underlying RNA modification-mediated processes and their impact on brain aging and the pathogenesis and progression of AD/ADRD. The ultimate goal is to identify targets for biomarker discovery and drug development for AD/ADRD.

Funding Details

Award Range

Not specified - $125,000

Total Program Funding

$4,000,000

Number of Awards

Not specified

Matching Requirement

Eligibility

Eligible Applicants

State governments

County governments

City or township governments

Special district governments

Independent school districts

Additional Requirements

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Geographic Eligibility

All

Key Dates

Next Deadline

October 1, 2024

Letter of Intent

Application Opens

October 1, 2024

Application Closes

November 1, 2024

Contact Information

Grantor

U.S. Department of Health and Human Services (National Institutes of Health)

grantsinfo@nih.gov

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