Tribal Injury Prevention Cooperative Agreement Program

The Tribal Injury Prevention Cooperative Agreement Program, offered by the Indian Health Service (IHS), aims to reduce injuries and violence among American Indian and Alaska Native (AI/AN) populations through community-driven, culturally responsive initiatives. This funding opportunity seeks to build capacity in AI/AN communities to address health disparities linked to preventable injuries, such as motor vehicle crashes, falls, opioid overdoses, firearm-related incidents, and other forms of trauma. With injuries remaining the leading cause of death among AI/AN individuals ages 1 to 54, the program is part of a longstanding effort by IHS to support Tribal and Urban Indian Organizations (UIOs) in mitigating these threats through localized prevention strategies. There are two distinct funding tracks under this opportunity, and applicants must choose only one. Part I provides up to $150,000 per year to support hiring a full-time Tribal Injury Prevention Coordinator and developing a comprehensive, multi-year prevention program. This part requires the applicant to serve an IHS user population of at least 2,500. Part II, offering up to $40,000 annually, focuses on smaller-scale, innovative projects and allows for more flexibility in staffing and implementation. Both parts support evidence-based or evidence-informed approaches that incorporate Tribal knowledge and prioritize community-led solutions. Funding is expected to span five one-year budget periods, with total program funding capped at $3 million and between 22 to 30 awards anticipated. There is no cost-sharing requirement. Pre-award costs are allowable up to 90 days before the project start date of January 1, 2026. IHS retains substantial involvement through the cooperative agreement mechanism, offering technical assistance, monitoring progress, and providing training, workshops, and evaluation support throughout the grant term. Eligible applicants include federally recognized Indian Tribes, Tribal organizations, and UIOs, as defined in 25 U.S.C. 1603. Supporting documentation, such as Tribal Resolutions and nonprofit proof, must be submitted with the application. Applications must be submitted through Grants.gov by 11:59 p.m. Eastern Time on November 13, 2025*. Required materials include project and budget narratives, a logic model, work plan, evaluation plan, and various forms and attestations as outlined in the NOFO. Applications are evaluated based on five weighted criteria: need for assistance, work plan and objectives, evaluation plan, organizational capacity, and budget justification. A risk review will also be conducted before funding decisions are finalized. Successful applicants will be notified via a Notice of Award and are expected to comply with all federal and program-specific administrative, financial, and reporting requirements. *Note that the grants.gov posting mentions that this opportunity is forecasted while the IHS site labels it as open with the NOFO confirming the November 13, 2025 due date. For any questions please reach out to DGM@ihs.gov.