Grants for Independent school districts - Health

This funding opportunity provides financial support for researchers to analyze existing data on late talking children, particularly focusing on underrepresented populations, to better understand their developmental trajectories and improve language outcomes.

This funding opportunity supports research projects that explore the link between social isolation and suicide risk in older adults, encouraging innovative interventions and service delivery models to enhance social connections and mental health.

This grant provides funding for research teams to study how early-life social and environmental factors influence brain development and addiction risk using animal models and advanced neuroscience techniques.

This cooperative agreement establishes the Hepatitis C Training and Implementation Center (HC-TIC) Network, which aims to accelerate the integration of hepatitis C prevention, testing, care coordination, and treatment interventions (program implementation) in priority high-impact settings through training and implementation TA. This cooperative agreement will improve and sustain the quality, availability, and reach of hepatitis C prevention and care activities in priority high-impact settings. Protection of public health and safety through the control and prevention of disease, injury, and disability in the U.S. and worldwide with attention to infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities.

The Community Foundation for Perry County, in partnership with the Foundation for Appalachian Ohio, is currently accepting grant applications. This program is designed to support nonprofits, schools, and public organizations undertaking projects and programs that directly benefit the residents and communities within Perry County, Ohio. The foundation's mission is deeply rooted in enhancing the quality of life for the Perry community, both in the present and for future generations. Established in 2012 by a collaborative effort of past and present residents, the core objective of CFPC is to build enduring funds and resources to create a tangible and lasting positive difference for Perry County. This initiative serves as an additional channel for residents to contribute locally, ensuring that resources specifically benefit the Perry County community and its citizens. The target beneficiaries of these grants are individuals of all ages within Perry County. The impact goals are centered around spearheading efforts that generate opportunities, address critical needs, and unlock the full potential residing within Perry County. The program's priorities and focuses are structured around five key areas of need, collectively referred to as the Pillars of Prosperity. These pillars encompass arts and culture, community and economic development, education, environmental stewardship, and health and human services. Projects and programs that align with and advance opportunities within these five areas will be prioritized for funding. The expected outcomes and measurable results of this grant program are broad, aiming to foster significant improvements across the identified Pillars of Prosperity. While specific quantitative metrics are not detailed in the provided information, the emphasis on creating opportunities, meeting pressing needs, and unleashing potential suggests a focus on tangible community development, improved access to essential services, enhanced educational outcomes, and strengthened cultural and environmental well-being within Perry County. The consideration of larger requests based on potential impact further indicates a desire for projects with substantial and transformative effects. Approximately $46,000 in funding is anticipated to be awarded this year. Grants typically fall within the range of $500 to $5,000, though applications for larger amounts will be given consideration if they demonstrate a greater potential for impact. The eligibility criteria are inclusive, allowing nonprofit organizations, including 501(c) organizations, public organizations such as school districts and government subdivisions, and even groups operating under fiscal sponsorship to apply, ensuring a wide reach for beneficial projects within the county.

This funding opportunity supports researchers and organizations developing innovative therapeutic leads for diseases related to diabetes, digestive, and kidney health, focusing on early-stage preclinical validation to advance potential treatments not currently pursued by major pharmaceutical companies.

The National Cancer Institute is offering funding for research projects aimed at validating the effectiveness of various markers and assays in cancer detection, diagnosis, treatment, and prevention, with a focus on developing these into clinical assays and ensuring their performance across multiple laboratories.

This funding opportunity supports researchers in developing innovative, safe, and noninvasive methods to assess the placenta's development and function throughout pregnancy, with the goal of improving maternal and fetal health outcomes.

This funding opportunity supports clinical research to explore and validate new non-invasive brain stimulation techniques for treating substance use disorders, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

Reissue of PA-18-350. The NIMH Exploratory/Developmental Grant program supports exploratory and high-risk research projects that fall within the NIMH mission by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough or to the development of novel techniques, agents, methods, measures, models, or strategies, or to the generation of pilot or feasibility data. The preliminary work from these studies could lead to a major impact on biomedical, behavioral, or clinical mental health research, or on the delivery of mental health care.

The "Coordinating Center for Type 1 Diabetes TrialNet" grant aims to fund the TrialNet Coordinating Center, which conducts research, trials, and studies to prevent the progression of type 1 diabetes and preserve insulin production, while also managing data, samples, and network operations, and promoting diverse perspectives in its work.

This notice of funding opportunity (NOFO) will support projects proposing mechanistic studies that will transform our understanding of polysubstance use in addiction. These hypothesis-based, exploratory projects may investigate mechanisms of polysubstance use at the behavioral, cognitive, cellular, circuit, genetic, epigenetic, pharmacological and/or computational levels. Research on substance use disorders (SUDs) has primarily focused on individual substances although polysubstance use is prevalent. Polysubstance use is the use of more than one addictive substance within a defined interval; the use may be sequential (use of multiple substances on separate occasions), or concurrent/simultaneous. Limiting studies to an individual addictive substance overlooks potential interactions between substances and could influence the translational potential of preclinical research findings. Results from several studies have demonstrated that the use of multiple addictive substances produces pharmacokinetic and behavioral profiles that are distinct from those produced by a single substance. Despite this recognition, little is known about the precise pharmacological mechanisms and interactions that may contribute to such outcomes, or co-morbidities resulting from co-use. There is also a significant lack in our understanding of how the activity of discrete cells, genes, circuits, expression of receptors, ion channels, intrinsic excitability or signaling mechanisms in the reward systems synergize when exposed to distinct classes of drugs simultaneously or sequentially. Even less is known about these mechanisms in brain regions and circuits that underlie negative reinforcement, or how neurotransmitters, neuromodulators or stress interact within these circuits to contribute to the behavioral and pharmacological profiles observed following polysubstance use. In addition, there is a need for behavioral models of polysubstance use that have translational potential. Research Objectives: The National Institute on Drug Abuse (NIDA) seeks to stimulate innovative research that will transform our understanding of the basic mechanisms that underlie polysubstance use in addiction. These studies will investigate novel neurobiological, pharmacological and/or behavioral mechanisms underlying the biobehavioral outcomes of polysubstance use. Research areas and questions of programmatic interest include, but are not limited to: Identification and/or characterization of molecules, genes, cells (including non-neuronal cells), neural pathways, circuits, receptors, ion channels, intrinsic excitability, pharmacological and signaling mechanisms mediating the effects of polysubstance use. Mechanisms underlying the association of early adolescent polysubstance use with SUD’s in adulthood. Sex differences in the development and trajectory of polysubstance use. What are the roles of organizational and activational effects of sex steroids on discrete brain regions and neural circuits, and how is this altered with exposure to polysubstance use? What are the developmental determinants? Are there developmental windows during which polysubstance use would be facilitated? What are the pharmacologic, pharmacokinetic and pharmacodynamic interactions that can impact toxicity, or the SUD trajectory? How do environmental factors interact with brain circuits to influence the development and trajectory of SUDs involving polysubstance use? How does stress interact with brain circuits to influence the development and trajectory of SUDs involving polysubstance use? Are there neurobehavioral risk phenotypes for progression to polysubstance use? What are the neurocognitive and neurobehavioral changes that occur through experience with different patterns of polysubstance use? Applications Not Responsive to this Notice of Funding Opportunity (NOFO) The following types of studies are not responsive to this NOFO and will not be reviewed: The major goal of the project is not targeted at delineating the basic mechanisms underlying polysubstance use in addiction. Projects limited exclusively to the phenomenology of polysubstance use, consequences of polysubstance use, or those focused exclusively on the development of tools or animal models. Projects that do not focus on combinations of two or more addictive substances with well-justified translational and public health relevance. Projects that do not include a psychostimulant, opioid, or cannabinoid in the polysubstance combination. Alcohol may be included in the polysubstance combination. Research that does not pertain to at least one of the stages of the substance use trajectory, including, but not limited to initiation, escalation, withdrawal and/or relapse. Other application considerations: Collaborative research teams to foster the sharing of conceptual and/or technical expertise are strongly encouraged. Applicants using animal models are encouraged to use models reflective of chronic and voluntary drug intake. Preliminary data are not required but may be included if available. In the absence of preliminary data, a strong premise should be provided for testing a novel hypothesis based upon the scientific literature as well as evidence of the team’s ability to carry out the proposed studies through published or technical preliminary data.

This funding opportunity is available to public and private nonprofit California licensed, certified or otherwise qualified substance use and/or mental health disorder providers, county and Tribal-based providers, crisis care mobile unit programs, community health centers, Federally Qualified Health Centers, Certified Community Behavioral Health Clinics, harm reduction service providers, recovery residences, transitional housing facilities, homeless shelters, youth-focused organizations, communitybased organizations, opioid treatment programs and office-based opioid treatment providers

This funding opportunity supports collaborative research on the long-term effects of adolescent alcohol use on brain function and behavior, inviting diverse institutions and organizations to participate in advancing treatment and prevention strategies for alcohol use disorders.

Computational fluid dynamics (CFD) has played a crucial role in providing an alternative bioequivalence (BE) approach for generic orally inhaled drug products (OIDPs), in addition to comparative clinical endpoint or pharmacodynamic BE studies, as a relatively cost- and time-efficient complement to benchtop and clinical experiments that has been widely used in developing and assessing generic inhaler devices. However, despite the advances in the power of modern computers, there are still some bottlenecks in using CFD due to computational time, limited grid resolution, pre- and post-processing of large simulation data sets, model parameter estimations, and uncertainty quantifications. Machine learning (ML) has been gaining more attention as a potential tool to alleviate such limitations that arise in CFD. The purpose of this grant is to develop a methodology to integrate ML with CFD models of OIDPs to promote alternative BE studies to enhance and accelerate the development and approval of generic OIDPs.

The Manistee County Community Foundation is seeking applications for projects that enhance the quality of life for residents of Manistee County. This grant program is aligned with the Foundation's mission to invest in projects that create a lasting impact on the community. The program aims to address root causes of issues, attract additional funding and resources, demonstrate collaboration, and target underserved community members. The target beneficiaries include all residents of Manistee County, with a particular focus on underserved individuals. The program also prioritizes projects that are accessible to participants regardless of their identity, physical, social, financial, or other circumstances, and those that incorporate diverse perspectives, especially from those who stand to benefit directly. The Foundation's priorities and focus areas encompass a broad range of community needs, including youth and education, arts and culture, the environment, health and human services, recreation, and community development. While not all elements are expected in every application, the Foundation generally seeks projects that demonstrate sustainability and coordination of efforts. Expected outcomes include projects being completed within one year of the grant award. Measurable results are implied through the focus on making a lasting impact on the community. The Foundation's strategic priorities are centered on fostering community well-being through targeted investments, and its theory of change appears to be that by funding projects addressing root causes and promoting collaboration, they can create sustainable positive change within Manistee County.

This funding opportunity provides financial support to community organizations and public agencies in California to develop and implement strategies that reduce gun violence and improve crisis intervention systems.

This funding opportunity supports early-stage researchers in cancer control and population sciences to explore innovative ideas that can significantly advance cancer research and improve healthcare delivery.

This funding opportunity supports researchers conducting basic science studies to explore how sleep and circadian rhythms are connected to substance use disorders, aiming to improve understanding and treatment of these issues.

The Central New York Community Foundation's Community Grant Program is designed to fund innovative projects across a range of vital areas, including arts and culture, civic affairs, education, health, human services, and the environment. This program aligns with the Foundation's broader mission to foster community impact, capacity building, and diversity within Onondaga and Madison counties. By supporting a wide array of initiatives, the Foundation aims to address pressing community needs and enhance the quality of life for residents in these regions. The primary beneficiaries of this grant program are nonprofit organizations serving residents of Onondaga and Madison counties. These organizations are encouraged to propose projects that lead to positive community impact, strengthen their own organizational capacity, and promote diversity. The ultimate impact goal is to create healthier, more vibrant, and more equitable communities through strategic investments in various sectors. The Foundation prioritizes projects that fall into three main categories: Capital Projects, Program support, and Organizational Development. Capital Projects can include large-scale campaigns, repairs, technology upgrades, and equipment purchases. Program support is allocated for new and innovative programs, or the expansion of existing, proven programs that directly address community needs. Organizational Development focuses on capacity-building efforts such as strategic planning, board development, and succession planning. The Foundation emphasizes that it does not typically fund annual operating budgets (unless it's seed or bridge funding), endowments, religious purposes, individual assistance, medical or academic research (unless donor-requested), or activities that occurred before the decision date. The expected outcomes of the Community Grant Program are multi-faceted, aiming to result in stronger community infrastructure, innovative solutions to social challenges, and more robust nonprofit organizations. Measurable results could include increased access to arts and cultural programs, improved educational outcomes, enhanced health services, stronger civic engagement, and a more protected environment. The Foundation's strategic priorities are implicitly linked to its funding categories, focusing on sustainable growth and impactful change. While a specific "theory of change" isn't explicitly detailed, the program's structure suggests a belief that targeted investments in key community areas, delivered through capable nonprofit partners, will lead to significant and lasting positive transformations for the residents of Onondaga and Madison counties.