Grants for Independent school districts - Health

This Funding Opportunity Announcement (FOA) invites applications to develop and implement Phase Ib to III clinical trials of promising pharmacological and non-pharmacological interventions that may prevent, delay, or treat the symptoms of Alzheimer's disease (AD) and other age-related dementias using the Alzheimer's disease Clinical Trials Consortium (ACTC) trial coordination and management infrastructure.Research Objectives Utilizing the ACTC, the goal of this FOA is to invite research grant applications that provide clinical testing (Phases Ib-III) of promising pharmacological and/or non-pharmacological interventions for cognitive and neuropsychiatric symptoms in individuals with AD or other aging-related dementias across the spectrum from pre-symptomatic to more severe stages of disease. Working with the ACTC is a cooperative venture between the applicant, the NIA, and the ACTC network. NIA and the ACTC leadership will provide guidance to potential applicants. Potential applicants are strongly encouraged to contact NIA Scientific/Research Contacts (see Agency Contacts, Section VII) and the ACTC study team in order to discuss the feasibility of conducting the proposed trial through the ACTC infrastructure before considering an application. The ACTC infrastructure is welcoming of the following: Academic and industry applicants Pharmacological and non-pharmacological interventions Applications are encouraged that propose the following: Testing candidate therapeutic compounds against novel therapeutic targets Testing repurposed drugs derived from data-driven approaches, including candidates coming from NIA's translational bioinformatics FOA (PAR-17-032) Logistical guidance: Potential applicants undergo initial vetting of proposed study by the ACTC protocol evaluation committee and final review by the steering committee. Applicants should contact the ACTC study team at least 5 months prior to their desired NIA submission cycle. Contact details and more information may be found at actcinfo.org. Applications should anticipate using a centralized IRB. Applicants should be aware of the data and resource sharing requirements. The use of common contract language is strongly encouraged. Note, the ACTC infrastructure is not appropriate for: Single site clinical trials Routine Phase Ia first-in-human Clinical trials funded from this FOA will be implemented through the ACTC. The clinical trials approved for funding will develop their final protocols in conjunction with the ACTC. All ACTC sites will have the option to request participation and will be selected based on their capabilities specific to the individual protocols. Investigators are strongly encouraged to collect blood and other biosamples for future genomic and other 'omic' analyses aimed at interrogating treatment responsiveness and examining predictors of decline and progression. See Section VIII. Other Information for award authorities and regulations.

This funding opportunity is designed to support higher education institutions, nonprofit organizations, and other eligible entities in establishing a coordination center to advance research on how our bodies sense and respond to internal signals, with a focus on improving mental health and overall wellness.

This funding opportunity supports innovative research exploring how social isolation and loneliness contribute to suicide risk among older adults, particularly focusing on underrepresented communities and various social factors.

NIEHS invites applications for cooperative agreements to support the development of model programs for the training and education of workers engaged in activities related to hazardous materials and waste generation, removal, containment, transportation and emergency response within the Department of Energy (DOE) nuclear weapons complex. The aim of this funding opportunity is to prevent work-related harm through safety and health training. The training programs consist of information and practical exercises with the objective of raising the knowledge of workers in protecting themselves and the community from being exposed to hazardous materials encountered during hazardous waste operations; facility decommissioning and decontamination; hazardous materials transportation; environmental restoration of contaminated facilities; or chemical emergency response. Currently, tens of thousands of DOE employees are required to complete safety and health training. The goal of this training is to help reduce the risk of workers being exposed during work activities to hazardous materials and hazardous waste products. The NIEHS/DOE Nuclear Worker Training Program enhances training capabilities at these sites.

The National Center for Advancing Translational Sciences (NCATS) intends to publish aNotice of Funding Opportunity (NOFO) to solicit applications for research to advance the diagnosis, management, and treatment of rare diseases. Each Rare Diseases Clinical Research Consortium (RDCRC) will promote highly collaborative, multi-site, patient-centric, translational, and clinical research. It is strongly encouraged that the RDCRC study outcome measures include those that address unmet clinical trial readiness needs that will move the field of research forward from its current state. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in winter 2024, with an expected application due date in summer 2024. This NOFO will utilize the U54 activity code, which supports specialized centers through multi-project cooperative agreement awards to support research activities with substantial involvement from NIH program staff. Details of the planned NOFO are provided below.

This funding opportunity supports organizations in planning and hosting an annual conference focused on advancing the development of treatments for substance use disorders, bringing together researchers, clinicians, and policymakers to foster collaboration and innovation in this critical public health area.

This funding opportunity supports research projects that aim to reduce health disparities related to HIV and substance use among underserved racial and ethnic populations in the U.S.

The purpose of this concept is to facilitate the formation and maintenance of multidisciplinary research teams ready to employ epidemiological and/or etiological datasets and analyses to answer substance use prevention research questions and apply findings to intervention development or implementation. Projects supported through this concept will combine hands-on meeting formats, including both sandpit and hackathon approaches, with activities to sustain new research teams and networks, creating a foundational structure for research programs that have impact across disciplines.

This funding opportunity provides financial support to a range of organizations working in Kenya to strengthen health systems for effective management and control of HIV and TB, while promoting sustainable healthcare practices and improving public health responses.

This funding opportunity supports interdisciplinary research centers focused on advancing the understanding and treatment of communication disorders, such as hearing and speech issues, through collaborative projects and clinical trials.

This funding opportunity supports advanced pre-clinical research projects that utilize nanotechnology to improve cancer treatment and diagnostics, aiming to transition these innovations toward clinical applications.

This funding opportunity supports early-career researchers in the U.S. to develop their skills in implementation science for effective substance use prevention and treatment, enabling them to lead clinical trials that address the opioid crisis.

This funding opportunity provides significant financial support to U.S. higher education institutions and research organizations with established HIV/AIDS research programs, enabling them to enhance their research infrastructure and foster interdisciplinary collaboration in the fight against HIV/AIDS.

The Office of Minority Health announces the anticipated availability of funds for Fiscal Year (FY) 2025 under the authority of 42 U.S.C. 300u-6 (Section 1707 of the Public Health Service Act) for a demonstration project that supports the development of a National Coordinating Center for Language Access Services . Demonstration projects are time-limited projects for the purpose of assessing the effectiveness of an approach or intervention toward reaching a desired outcome. We expect award recipients under this opportunity to consider approaches to sustainability beyond the end of the support provided by OMH.Individuals with limited English proficiency face barriers to health care and social services that increase their risk for poor health outcomes. We intend for the funded project to create a National Coordinating Center to connect health and human service professionals with qualified health language interpreters and translators to improve access to language services for individuals limited English proficiency. The funded project will develop technical components needed to host the Center, connect and engage a collaborative network of community-based organizations, and promote the Center nationally to health and human service organizations and agencies. OMH also expects the project to address gaps in access to language services and improve the quality of care and health outcomes for individuals with limited English proficiency. Eligible applicants include any private nonprofit or public entity located in a State. State includes, in addition to the several States, only the District of Columbia, Guam, the Commonwealth of Puerto Rico, the Northern Mariana Islands, the Virgin Islands, American Samoa, the Trust Territory of the Pacific Islands, and any agency or instrumentality thereof exclusive of local governments. (42 U.S.C. 201(f) (PHS Act, Section 2(f)), 45 C.F.R. 75.2). Eligible entities include private nonprofit or public faith-based organizations, community-based organizations, and American Indian/Alaska Native/Native American (AI/AN/NA) organizations. Applications must be submitted through Grants.gov, and applicants must have an active SAM.gov registration when submitting an application. Interested applicants are strongly encouraged begin the registration process for both systems early.

This funding opportunity provides financial support to research institutions for developing and sharing essential resources to advance the study of Polycystic Kidney Disease, fostering collaboration and innovation in the field.

The Blue Cross and Blue Shield of North Carolina Foundation is offering a grant program aimed at expanding access to mental and behavioral health services and resources for youth. This initiative aligns with the foundation's mission to improve the health and well-being of North Carolinians by focusing on critical health needs. The program seeks to support models that are effective in the short term (1-3 years) and leverage a trained workforce beyond traditional specialty-trained clinical roles. This strategic approach emphasizes immediate impact and sustainable community engagement, reflecting a theory of change that posits empowering a broader range of professionals will lead to more accessible and responsive mental health support for young people. The primary target beneficiaries of this grant are youth in North Carolina, particularly those in communities facing significant barriers to accessing care. The program aims to address the critical need for mental and behavioral health support by increasing the availability of resources and services. Impact goals include fostering early identification of distress, trauma, mental health changes, or substance use among youth, and facilitating their connection to appropriate resources. The foundation prioritizes approaches that engage diverse communities and can operate in various settings, such as communities, schools, health systems, and faith-based organizations. The program's priorities include strengthening organizational capacity and infrastructure, connecting care across different settings, increasing access to training opportunities for a diverse workforce, and enhancing the availability of culturally and linguistically relevant resources and materials. The focus is on a trained workforce that can identify, understand, and respond to signs and symptoms of mental health challenges, providing initial support and resource connection. This strategy aims to create a more integrated and accessible support system for youth mental and behavioral health. Expected outcomes include a measurable increase in the number of youth accessing mental and behavioral health services, improved early intervention for mental health concerns, and a more robust network of trained professionals capable of supporting youth. The grant allows for proposals ranging from $75,000 to $500,000 per year for up to three years, indicating a commitment to significant, multi-year projects. Eligible organizations include nonprofits, fiscally sponsored programs, government entities (including schools and tribal governments), and coalitions, fostering a broad and inclusive approach to addressing youth mental health needs across all counties in North Carolina.

This grant provides funding for early-career researchers to conduct health-related studies that benefit individuals affected by the September 11, 2001, terrorist attacks, focusing on improving diagnosis and treatment for various health issues.

This grant provides funding to neuroscience researchers to advance their small molecule drug discovery and development projects aimed at treating disorders of the nervous system.

This funding opportunity supports academic and industrial partnerships to develop new vaccines aimed at preventing tuberculosis infection and disease, addressing the urgent need for effective solutions against rising TB rates.

This funding opportunity provides financial support to various organizations to assist the Botswana Ministry of Health in implementing effective HIV prevention and treatment programs, particularly for underserved populations.