Grants for Nonprofits - Health

This funding opportunity supports U.S. institutions and organizations in developing animal models and biological resources to advance research on Down syndrome and its related health conditions.

This funding opportunity provides support for the ongoing development and maintenance of valuable informatics tools and resources that enhance cancer research and management, benefiting researchers and the broader cancer community.

This grant provides professional-grade electric lawn equipment to non-profit organizations in Louisville/Jefferson County, Kentucky, to promote sustainability and improve air quality by replacing gas-powered tools.

This program provides funding to nonprofit organizations in Centre County, Pennsylvania, to support projects that positively impact local youth, focusing on areas like mental health, educational equity, and access to extracurricular activities.

This grant provides financial support to urban farmers in Minnesota for implementing conservation practices that improve environmental health and farm sustainability.

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. Section I. Funding Opportunity Description The overall goal of the NIH Research Career Development program is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs. NIH Institutes and Centers (ICs) support a variety of mentored and non-mentored career development award programs designed to foster the transition of new investigators to research independence and to support established investigators in achieving specific objectives. Candidates should review the different career development (K) award programs to determine the best program to support their goals. More information about Career programs may be found at the NIH Extramural Training Mechanisms website. The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is designed to enable mid-career clinician-scientists to: Devote more time to augment their capabilities in Patient-Oriented Research (POR); and Provide mentoring to junior clinical investigators in the conduct of POR (see below for definition). The K24 award is intended to provide protected time to mid-career clinical investigators to provide mentoring to junior clinical investigators, particularly K23 grantees, in POR and to stabilize the careers of these investigators. The intent is to allow these investigators to continue to conduct POR and be available as mentors in POR. It is expected that K24 recipients will obtain new or additional independent, peer-reviewed funding for POR as PD/PI and establish and assume leadership roles in collaborative POR programs. In addition, it is expected that there will be an increased effort and commitment to act as a mentor to beginning clinician investigators in POR to enhance the research productivity of both the K24 investigator and increase the pool of well-trained clinical researchers of the future. For the purposes of the K24 award, Patient-Oriented Research is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects. This area of research includes: (1) mechanisms of human disease; (2) therapeutic interventions; (3) clinical trials, and; (4) the development of new technologies. Excluded from this definition are in vitro studies that utilize human tissues but do not deal directly with patients. In other words, patient-oriented research is research in which it is necessary to know the identity of the patients from whom the cells or tissues under study are derived. Studies falling under Exemption 4 for human subjects research are not included in this definition. See also the NIH Director's Panel on Clinical Research Report. NIH defines a clinical trial as "A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes." (NOT-OD-15-015). NIH not only supports trials of safety and efficacy, it also supports mechanistic exploratory studies that meet the definition of a clinical trial and are designed to explore or understand a biological or behavioral process, the pathophysiology of a disease, or the mechanism of action of an intervention. These studies may focus on basic and/or translational discovery research in healthy human subjects and in human subjects who are affected by the pathophysiology of diseases and disorders. By addressing basic questions and concepts in biology, behavior, and pathophysiology, these studies may provide insight into understanding human diseases and disorders along with potential treatments or preventive strategies. NIH also supports biomarker studies that meet the definition of a clinical trial and that may provide information about physiological function, target engagement of novel therapeutics, and/or the impact of therapeutics on treatment response. NIH thus supports studies that meet the definition of clinical trials (as noted above) but do not seek to establish safety, clinical efficacy, effectiveness, clinical management, and/or implementation of preventive, therapeutic, and services interventions. Note: This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA Special Note: Because of the differences in individual Institute and Center (IC) program requirements for this FOA, prospective candidates are strongly encouraged to consult the Table of IC-Specific Information, Requirements and Staff Contacts, to make sure that their application is appropriate for the requirements of one of the participating NIH ICs. See Section VIII. Other Information for award authorities and regulations. Section II. Award Information Funding Instrument Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed New Resubmission Revision Renewal The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this FOA. Clinical Trial? Required: Only accepting applications that propose an independent clinical trial(s) Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Award Budget Award budgets are composed of salary and other program-related expenses, as described below. Award Project Period The total project period may not exceed 5 years.

This grant provides funding for research on behavioral sleep interventions aimed at improving sleep and mental health outcomes for adolescents and young adults, particularly those from underserved populations.

Johnson County is issuing a Request for Proposal (RFP) for Permanent Supportive Housing, specifically designed for households with children. The program aims to reduce barriers to housing and promote housing stability through trauma-informed, culturally responsive, and interdisciplinary services. These services must effectively engage families with complex needs, being comprehensive, coordinated, readily accessible, and family-centered. A key focus of this RFP is to demonstrate racial equity in the provision of proposed services, aligning with a mission to address systemic inequalities in housing access and stability. The target beneficiaries for this program are families experiencing repeated and/or chronic homelessness, with incomes at or below 30% of the area median income as defined by HUD at the time of entering housing. This population often faces multiple barriers to housing stability, including poverty, brain health disorders, substance use, and other chronic health conditions. The program's impact goals are to provide housing stability for these families, ultimately leading to other positive outcomes beyond just housing, such as improved health and overall well-being. The program prioritizes a Permanent Supportive Housing (PSH) model, which combines affordable housing with voluntary support services. This intervention is a proven successful model in providing housing stability for families experiencing long-term homelessness. The expected outcomes include a reduction in repeated and chronic homelessness for the target population, as well as improved housing stability. Measurable results would likely include tracking the number of families housed, the length of time families remain housed, and improvements in associated social and health indicators. Funding of up to $220,000 will be awarded annually under this RFP, with the possibility of renewal for up to three years. The contract term is from July 1, 2024, to June 30, 2025. Eligible organizations are nonprofit organizations providing services in and for Johnson County residents. This initiative reflects a strategic priority of Johnson County to support its vulnerable populations through a comprehensive and equity-focused approach to housing, embodying a theory of change that by providing stable housing and robust support services, long-term homelessness can be effectively combated and families can achieve greater overall well-being.

This funding opportunity provides financial support for research sites to study Type 1 diabetic nephropathy by recruiting patients, conducting kidney biopsies, and collecting data to identify new treatment targets and improve precision medicine approaches.

This funding opportunity supports nonprofit organizations and public agencies in their efforts to combat poverty through community empowerment and sustainable solutions in areas such as economic opportunity, education, and environmental stewardship, with a focus on advancing racial equity and serving underserved communities.

Substance use needs to be better incorporated into interventions for the engagement and retention of sexual minority persons in prevention and care with attention to emergent interventions such as long-acting PrEP. Social determinants of health associated with HIV and problematic substance use such as homelessness and criminal justice involvement also demonstrate disproportionate impact among sexual and gender minorities and need attention. Changing self-definition of sexual minority status has implications for outreach and provider stigma and needs to be better integrated into interventions. This initiative will address these gap areas and support epidemiologic, intervention, and implementation research that incorporates attention to HIV as a syndemic including comorbidities such as STIs, HCV, and psychiatric disorder.

This grant provides funding to U.S. institutions to foster collaboration and support early-career researchers in benign urology through training, resource sharing, and professional development opportunities.

This grant provides funding for short-term therapeutic programs that support transition age youth with or at risk of child welfare involvement, helping them develop the skills and resources needed for successful independent living.

This funding opportunity supports a central coordinating center that will enhance collaboration and provide resources for research in nonmalignant hematology, particularly aimed at fostering the development of junior investigators and innovative projects across multiple institutions.

This funding opportunity supports innovative research projects that aim to improve the use of genomic information in clinical care, particularly for diverse and underrepresented populations, while addressing health disparities and enhancing the integration of genomic medicine into healthcare practices.

The United Airlines Trust Fund was established in recognition of Siouxland's response to the United Flight 232 incident in 1989. This grant supports organizations and government units within a 50-mile radius of Sioux City, Iowa. Eligible entities include 501(c)(3) organizations and qualified government units. The fund allocates two-thirds of its annual net income to scholarships and one-third to community grants. These grants support projects promoting public safety, health care, crisis management, and community preparedness, with a focus on social services, education, and training of public personnel. Grants typically do not exceed $2,500, and the selection is based on proposal merit, relative need, and potential community impact. Grant renewed every year. Grant Annual opening/closing deadline: February 15th to May 15th

This funding opportunity provides financial support for research on the role of inflammasomes in the brain related to HIV and substance use disorders, targeting innovative studies that explore their impact on inflammation and neurocognitive health.

This grant provides funding for interdisciplinary research teams to explore the ethical implications of new neurotechnologies and brain science advancements, focusing on issues like data privacy, informed consent, and public attitudes toward brain research.

The "Closing inequities in HIV Prevention, Care and Treatment among key populations in Burkina Faso Activity (Equity KP Burkina Faso)" grant aims to support local entities in Togo and Burkina Faso in providing quality HIV services, improving the environment for key populations and their partners, and enhancing monitoring and sustainability efforts for HIV epidemic control by 2030.

This funding opportunity is designed to support educational projects that improve healthcare professionals' understanding of biomarker testing and PARP-inhibitor treatments for metastatic prostate cancer, targeting community oncologists, urologists, and other related healthcare providers.