Grants for Public housing authorities - Health

This funding opportunity supports researchers in discovering and validating new targets for developing safe and effective pain treatments with minimal side effects and low addiction risk.

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications for Senator Paul D. Wellstone Muscular Dystrophy Specialized Research Centers (MDSRCs). These Centers promote collaborative basic, translational, and clinical research and provide important resources that can be used by the national muscular dystrophy research community. A goal of this Centers program is to support important and innovative research in the muscular dystrophies that is best pursued through an interdisciplinary and collaborative center environment and projects that may not be as effective if supported by "stand-alone" research project grants. The Centers also provide outstanding environments for the training of new scientists electing to pursue careers conducting research in high priority areas of muscular dystrophy. Finally, Center investigators are expected to engage the patient and advocacy communities in conversations to increase awareness of research, encourage patient participation in research, and incorporate the perspectives of these communities in the conduct of patient-centered research.

This Funding Opportunity Announcement (FOA) will support extramural research to investigate and mitigate challenges facing clinical assay development and subsequent analytical validation due to preanalytical variability in tumor tissue biopsies, blood biospecimens utilized as liquid biopsies", or other biospecimens as described in this FOA. Extramural research funded under this FOA may include investigations of preanalytical variability associated with the procurement and study of small biopsies (core biopsies, small excision samples), blood utilized for "liquid biopsies", tissue swabs, tissue secretions, pleural and esophageal aspirates, feces, or bodily fluids like sweat, urine, CSF, breast milk and saliva. Investigator-designed experiments will explore how different biospecimen preanalytical conditions affect emerging and clinically relevant biomarkers quantified by a variety of testing platforms. The results from this research program will improve the understanding of how analytical quantification of clinically relevant biomarkers is affected by variation in biospecimen collection, processing, and storage procedures. The overall goal is to expedite biomarker clinical assay development through evidence-based standardization of biopsy handling practices.

The "Modulating Human Microbiome Function to Enhance Immune Responses Against Cancer" grant aims to fund preliminary research into how the human microbiome affects the body's immune response to cancer, with a focus on how specific microbes or their byproducts can either increase or prevent tumor formation, and how the amount, timing, and duration of beneficial microbes can impact their effectiveness.

This funding opportunity supports the development of a national data resource center to improve research on childhood cancers and congenital anomalies, encouraging collaboration among a wide range of organizations and researchers.

This funding opportunity provides financial support for educational programs that train new researchers in Down syndrome to improve understanding and treatment of co-occurring health conditions throughout the lifespan.

This grant provides funding for researchers at U.S. institutions to explore innovative uses of nanotechnology in cancer research, focusing on improving targeted delivery and diagnostic capabilities for specific cancer types.

This funding opportunity supports research institutions and organizations in developing and testing new treatments and recovery methods for individuals with alcohol use disorder, particularly focusing on underserved populations and innovative approaches.

The "Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research" grant aims to encourage current NCI R01 research projects to incorporate new technologies from the NCI Innovative Molecular Analysis Technologies program, with the goal of enhancing their original research and speeding up scientific discoveries in cancer research.

This funding opportunity provides financial support to organizations working in Zambia to improve HIV and TB prevention, care, and treatment services through innovative and sustainable quality improvement strategies.

This funding opportunity provides financial support to organizations that will coordinate and advance the use of artificial intelligence and technology in aging research, particularly in addressing Alzheimer's Disease and related dementias.

The overall goal of this UG3/UH3 Exploratory/Developmental phased initiative is to support the discovery and development of novel natural products that are safe, nontoxic, and efficacious for cancer interception and prevention. 1. Purpose of UG3: Select clinically relevant targets and develop and validate assays for bioactivity as well as toxicity screening 2. Purpose of UH3 phase: Screening libraries, structure elucidation, full-scale characterization, efficacy testing, and development of the screened agents.

This grant provides access to specialized resources and expertise for researchers developing gene-based therapies for extremely rare neurological disorders, helping them prepare for regulatory submissions and advance their therapeutic projects.

This Notice of Funding Opportunity (NOFO) invites applications for a U54 Specialized Center (henceforth: Consortium) to provide resources, expertise, and coordination to advance innovative, high-quality research on palliative care for those with serious illness across the lifespan. This research infrastructure will encompass Alzheimers disease and Alzheimers disease-related dementias (AD/ADRD), cancer, and other serious illnesses and populations relevant to the partnering Institutes, Centers, and Offices (ICOs). NIH currently funds many palliative care research projects across the ICOs, and there is a need for a structure to leverage synergies, coordinate efforts, develop the scientific workforce, and address remaining gaps in the field. The goals of this initiative include generating new scientific knowledge, in part through supporting pilot and exploratory studies; fostering development of early- and mid-career palliative care investigators; serving as a national platform to provide research resources and facilitate high-quality palliative care research; engaging healthcare systems and community-based organizations as research partners and settings for palliative care research; and disseminating research findings, best practices, data, and other impactful resources to the palliative care research and clinical communities. An important focus of the Consortiums work will be on facilitating research to understand and address disparities in access, quality, and use of palliative care services for health disparities populations or in underserved areas.

The "Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research" grant aims to encourage existing NCI P50 specialized centers to enhance their current cancer research by integrating new technologies or methods developed by the NCI Innovative Molecular Analysis Technologies program.

This funding opportunity provides financial support for research projects that implement effective treatments for opioid and stimulant use disorders, focusing on improving care systems and addressing health disparities.

This grant provides funding for researchers to conduct preclinical studies on the effects of radionuclide-based cancer therapies, aiming to improve treatment strategies and outcomes for cancer patients.

This funding opportunity is designed to establish a center that will coordinate and manage data for collaborative research on rare diseases, supporting various research consortia and engaging stakeholders to improve diagnosis and treatment.

The "Clinical Trial Readiness to Understand and Develop Solutions to Social, Ethical, Behavioral Implications and Barriers to Health Equity in ADRD" grant aims to fund research that prepares for clinical trials focused on understanding and addressing the social, ethical, and behavioral barriers that prevent equal health outcomes for Alzheimer's Disease and Related Dementias (ADRD) in underserved and marginalized communities.

This initiative will support innovative, collaborative, and multi-disciplinary research designed to study the effective adaptation, integration, and implementation of recommended guidelines of care of persons with multiple chronic conditions (MCCs) from populations that experience health disparities. Projects would be expected to involve more than one component and/or more than one level of influence within existing or newly proposed health care models. The ultimate goal of this initiative is attainment of optimal treatment and health outcomes goals in order to move towards health equity.