Grants for Small businesses - Health

This Notice informs that NIA intends to publish a Notice of Funding Opportunity (NOFO) inviting applications from mid-career investigators for mentored career enhancement awards focused on cross-disciplinary training to broaden and strengthen the investigator's capability to lead future comparative studies of the factors contributing to differences in life spans between human and nonhuman primate species. The NOFO is intended to provide support for experienced investigators with expertise in human and/or nonhuman primate (NHP) studies to do the following: 1) Augment or redirect their research program by acquiring expertise in other fields related to comparative primate research and aging 2) Develop collaborations with research fields with which they do not commonly interact This Notice is being provided to allow potential applicants sufficient time to identify potential mentors and prepare well-developed career enhancement plans. The NOFO is expected to be published in June 2024 with an anticipated application due date in November 2024. These are estimated time frames, and they may change. The NOFO is expected to utilize the K18 Career Enhancement Award activity code. It is expected that the NOFO will not allow clinical trials. Additional details of the planned NOFO are provided below.

This funding opportunity provides financial support to small businesses in the U.S. for conducting exploratory clinical trials or biomarker validation studies aimed at advancing therapies for neurological disorders.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of small molecules that function to elucidate the biology of disease as chemical probes or function as agonists or antagonists of disease target(s) for therapy or immunotherapy. The NOFO is intended to support discovery research for the identification of validated hits relevant to health-related outcomes of participating NIH Institutes. Stages of discovery research covered by this NOFO include: 1) assay development for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; 2) screen implementation high throughput target-focused approaches or moderate throughput phenotypic- and fragment-based approaches to identify initial screening hits; 3) hit validation, including implementation of secondary assays that are orthogonal to the primary assay, advanced cheminformatics analysis and initial medicinal chemistry inspection to prioritize the hit set, and follow-up assays to characterize mode and mechanism of action of the validated hits; 4) hit-to-lead optimization, including SAR to optimize target engagement, selectivity and to minimize chemical liabilities, ADME, PK and PD studies, and, if appropriate, in vivo modeling to test efficacy or biological effects.

This funding opportunity provides financial support for researchers to analyze existing data on late talking children, particularly focusing on underrepresented populations, to better understand their developmental trajectories and improve language outcomes.

This fellowship provides support, resources, and funding to U.S. entrepreneurs developing scalable solutions in climate, health, and equity, with a focus on historically underrepresented founders.

This funding opportunity supports clinical research to explore and validate new non-invasive brain stimulation techniques for treating substance use disorders, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

This funding opportunity supports collaborative research on the long-term effects of adolescent alcohol use on brain function and behavior, inviting diverse institutions and organizations to participate in advancing treatment and prevention strategies for alcohol use disorders.

This funding opportunity supports U.S.-based small businesses in developing innovative, non-addictive therapies and technologies for improved pain management, addressing the opioid crisis through preclinical research and technological advancements.

The City of Alhambra in California is offering a Small Business Assistance Grant Program to support local small businesses affected by the COVID-19 pandemic. Eligible businesses must either serve a U.S. Department of Housing and Urban Development (HUD) defined low- and moderate-income area within Alhambra or be owned by low- and moderate-income individuals.Groups of neighbors must find a host organization to sponsor the project and act as the project fiduciary. Applications are accepted year-round until funds are exhausted.

This funding opportunity supports the development of innovative therapies to counteract the effects of Botulinum Neurotoxin, targeting researchers and organizations focused on advancing treatments for this serious health threat.

This funding opportunity provides financial support to organizations working in Namibia to improve health information systems and enhance public health programs related to HIV, tuberculosis, and other health threats.

This funding opportunity supports early postdoctoral fellows from diverse backgrounds in cancer research, providing mentorship and training to help them address health disparities and advance their careers in the field.

Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders that fall under the NINDS mission. Therapeutic agents include small molecules, biologics or biotechnology-derived products. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.

Public Health – Seattle & King County is offering a grant of $100,000 to $500,000 for projects that support diverse youth mental health providers, particularly those connected to LGBTQIA and BIPOC communities, with the aim of increasing access to mental health resources, improving retention, and supporting diverse providers in King County, Washington.

The United States Agency for International Development Mission in Indonesia (USAID/Indonesia) posts this Request for Information (RFI) to inform interested parties of an upcoming health system strengthening (HSS) activity designed to improve accountability, health system performance and health outcomes (especially for Maternal and Child Health, Tuberculosis, HIV, and Global Health Security) based on performance-based and sustainable health financing, a strengthened health information system, resilient human resources for health, integrated care models, and a strong evidence to policy pathway.This Request for Information (RFI) is issued solely for information gathering purposes and is published in accordance with FAR Part 10 and FAR Part 15.201(e).Through this RFI, USAID/Indonesia seeks to enhance the design of the HSS Flagship Activity in Indonesia. This RFI seeks information from capable organizations (i.e., nongovernmental organizations, universities, consortium, for-profit, and local organizations) that are implementing or have implemented HSS projects that spans more than one health system building block and may be interested to partner with USAID in achieving the goals of this future HSS activity. All capable organizations are encouraged to respond.This RFI does not constitute a Request for Applications (RFA) or a Request for Proposals(RFP). Responses to this RFI are not applications or official proposals and will in no way be deemed to form any binding agreement with the RFI issuing authority. Please do not submit applications, proposals, budget, costs, resumes or promotional materials, as they will be discarded. Proprietary information should not be sent. USAID may use any information provided without incurring any obligation. USAID reserves the right to, or not to incorporate any, some, or none of the comments received from this RFI into any subsequent solicitations or design documents.(See further information in Related Documents Tab)

This funding opportunity supports a variety of organizations in developing innovative technologies to identify and target senescent cells, which could lead to new treatments for age-related diseases.

This funding opportunity provides financial support for research projects that explore and improve crisis response services for suicide prevention, particularly targeting diverse and underserved populations.

The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. This Funding Opportunity Announcement (FOA) supports preclinical discovery and development of potential therapeutic Biotechnology Products and Biologics including, but not limited to, large biologic macromolecules, (e.g., proteins, antibodies, and peptides), gene-based therapies (i.e., oligonucleotide- and viral-based), cell therapies, and novel emerging therapies (e.g., microbial and microbiome therapies). Applicants will collaborate with NIH-funded consultants and can augment their project with NIH contract research organizations (CROs) that specialize in manufacturing, scaling, pharmacokinetics, toxicology, and Phase I clinical testing. BPN-Biologics awardee institutions retain their assignment of IP rights and gain assignment of IP rights from the BPN-Biologics contractors (and thereby control the patent prosecution and licensing negotiations) for biotherapeutic candidates developed in this program.

This funding opportunity is designed for organizations to collect and analyze data on state and federal prison populations, focusing on admissions, releases, and demographic trends, while also addressing opioid use disorder screening and treatment in prisons.

This grant provides funding for small-scale cancer research projects that can be completed in two years, aimed at supporting innovative studies and methodologies in various areas of cancer research.