Grants for For profit organizations other than small businesses - Science and Technology

This grant option, part of the Minnesota Spinal Cord Injury and Traumatic Brain Injury Research Grant Program, aims to support early-stage research into innovative treatments and rehabilitative techniques for spinal cord and traumatic brain injuries. The Tier 1 Pilot Project Grant does not require preliminary data but encourages it, reflecting early investment as researchers prepare to seek larger grants. The funding amount can reach up to $125,000 for a project duration of two years with an additional one-year no-cost extension.

The Era of Hope Scholar Award supports individuals early in their careers who have demonstrated significant potential to effect meaningful change in breast cancer. These individuals should be exceptionally talented scientists who have shown that they are the best and brightest in their field(s) through extraordinary creativity, vision, innovation, and productivity. They should have demonstrated experience in forming effective partnerships and collaborations and must exhibit strong potential for future leadership in breast cancer research.As the intent of the Era of Hope Scholar Award is to recognize creative and innovative individuals rather than projects, the central features of the award are the demonstrated ability of the individual named as the Principal Investigator (PI) in the application to go beyond conventional thinking in their field and the innovative contribution that the PI can make toward ending breast cancer. The application should articulate a vision that challenges current dogma and demonstrates an ability to look beyond tradition and convention.Experience in breast cancer research is not required; however, the application must focus on breast cancer, and the PI must commit a minimum of 25% level of time and effort during the period of performance to conduct breast cancer research under this award. Individuals from other disciplines who apply novel concepts to breast cancer are encouraged to submit.The PI is encouraged to assemble a research team that will provide the necessary expertise and collaborative efforts toward accomplishing the research goals. The PIs research team must include two or more breast cancer consumer advocates. As lay representatives, the consumer advocates must be individuals who have been diagnosed with breast cancer and are actively involved in a breast cancer advocacy organization. Their role should be independent of their employment, and they may not be employees of any organizations participating in the application. The consumer advocates should have a high level of knowledge of current breast cancer issues and the appropriate background and/or training in breast cancer research to contribute to the project. Their role should be focused on providing objective input throughout the research effort and its potential impact for individuals with, or at risk for, breast cancer.A congressionally mandated Metastatic Cancer Task Force was formed with the purpose of identifying ways to help accelerate clinical and translational research aimed at extending the lives of advanced state and recurrent patients. As a member of the Metastatic Cancer Task Force, the CDMRP encourages applicants to review the recommendations (https://health.mil/Reference-Center/Congressional-Testimonies/2018/05/03/Metastatic-Cancer-Research) and submit research ideas to address these recommendations provided they are within the limitations of this funding opportunity and fit within the FY24 BCRP priorities.Innovative research involving nuclear medicine and related techniques to support early diagnosis, more effective treatment, and improved health outcomes of active-duty Service Members and their Families is encouraged. Such research could improve diagnostic and targeted treatment capabilities through noninvasive techniques and may drive the development of precision imaging and advanced targeted therapies.The CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women’s health outcomes and/or advancing knowledge for women’s health.The proposed research must be relevant to active-duty Service Members, Veterans, military beneficiaries, and/or the American public. Collaborations between researchers at military or Veteran institutions and non-military institutions are strongly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the partners bring to the research effort, ultimately advancing cancer research that is of significance to the Warfighter, military Families, and the American public.Clinical trials are allowed. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.The funding instrument for awards made under the program announcement will be grants (31 USC 6304).The anticipated direct costs budgeted for the entire period of performance for an FY24 Era of Hope Scholar Award should not exceed $3.5M. Refer to Section II.D.5, Funding Restrictions, for detailed funding information.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $5.4M to fund approximately one Era of Hope Scholar Award application. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.

This funding opportunity provides financial support to U.S.-based small businesses that have previously received Phase I awards to further develop and commercialize innovative research in agriculture, food systems, and environmental sustainability.

The DoD Traumatic Brain Injury and Psychological Health, Translational Research Award aims to fund research that accelerates the application of findings in psychological health and traumatic brain injury into clinical practice, leading to the development of healthcare products, technologies, or clinical practice guidelines that improve patient outcomes.

This grant provides funding to early-stage companies in the U.S. and Canada that are developing innovative software and AI solutions aimed at combating climate change and promoting sustainability.

This program provides funding to non-profits, businesses, and government agencies in Clinton County to promote tourism, develop attractions, and host events that encourage overnight visits and boost the local economy.

The CATALYST Grant aims to enhance the capabilities, efficiency, and competitiveness of small and medium-sized manufacturers in South Carolina by promoting the adoption of Advanced Manufacturing Technologies (AMT), Quality Management Systems (QMSs), and Lean Manufacturing tools. Eligible manufacturers must have a NAICS code beginning with 31, 32, or 33, be physically located in South Carolina for at least one year, operate within the Department of Defense supply chain, and employ at least four workers. The grant supports consultative assessments to identify opportunities for AMT deployment and funds pilot projects in areas such as augmented reality training, digital work instructions, and robotics. The grant application opens on October 5, 2023, following an informational webinar, and closes on June 30, 2024, or when all slots are filled. The grant provides funding for projects recommended by AMT assessments, as well as QMS and Lean Manufacturing implementations to help manufacturers eliminate waste and reduce rework, improving their effectiveness as DIB suppliers.

This funding opportunity supports U.S.-based small businesses in developing and manufacturing therapeutic extracellular vesicles for regenerative medicine applications, focusing on tissue and organ repair.

The Historic Downtown Kennewick Partnership, in collaboration with the City of Kennewick’s Community Development Department, has relaunched the Downtown Kennewick Façade Improvement Grant Program. This initiative aims to enhance the visual appeal of downtown Kennewick by fostering a cohesive image, promoting coordinated signage and store graphics, and complementing existing building façades. The program offers grants ranging from $10,000 to $100,000, with up to $25,000 per storefront, to support improvements. This program aligns with the broader mission of revitalizing and developing the downtown area, contributing to economic growth and community pride. The primary beneficiaries of this program are property owners and businesses within the designated target area of downtown Kennewick. The impact goals are centered on creating a more attractive and vibrant downtown environment, which in turn is expected to draw more visitors and customers, stimulate local commerce, and encourage further investment in the area. By improving the aesthetics of storefronts, the program directly addresses the need for a unified and appealing commercial district. The program prioritizes eligible improvements such as cleaning and painting, new awnings, canopies, and signs, gutters and downspouts, exterior wall repairs, building-mounted lighting, door and window repairs and replacements, and accessibility improvements. A key focus is on ensuring projects comply with the City of Kennewick Façade Improvement Program Underwriting Guidelines and are evaluated for consistency with an approved color palette by the Historic Downtown Kennewick Partnership’s Design Committee. The committee specifically encourages a sophisticated and restrained application of color, using vibrant hues for highlights and trim, and softer tones for main building elements. Expected outcomes include a visibly improved downtown area with enhanced curb appeal and a more unified architectural style. Measurable results will likely involve the number of storefronts that undergo renovations, the total investment leveraged by the grants, and potentially increased foot traffic or business activity in the revitalized areas. The underlying theory of change is that by investing in physical improvements and enhancing the aesthetic quality of downtown façades, the program will create a more inviting and economically dynamic environment, leading to increased community engagement and sustained revitalization efforts. The program’s strategic priorities are clearly focused on visual improvement and adherence to design guidelines to achieve these broader community development goals.

This fellowship supports U.S.-based documentary filmmakers working on impactful projects by providing funding, mentorship, and networking opportunities to enhance their storytelling skills.

The FY24 DMDRP CTRA mechanism supports advanced translational research that will accelerate the movement of promising ideas in DMD research into clinical applications. Translational research may be defined as an integration of basic science and clinical observations. However, applicants should not view translational research as a one-way continuum from bench to bedside. The research plan must involve a reciprocal flow of ideas and information between applied and clinical research. As such, applications must include preliminary and/or published data relevant to DMD to support the proposed research project.This mechanism is intended to support established projects that have moved beyond the realm of basic research and proof of concept studies and have the potential to result in a near-term impact in clinical research or the clinic. Research projects investigating therapies that will be efficacious across the life span, including infants, toddlers, and non-ambulatory individuals, are strongly encouraged. Pilot, proof-of-principle clinical trials, and correlative studies to better inform development of drugs, devices, and other interventions are allowed.Early-Career Partnering PI Option: The FY24 DMDRP encourages applications that include meaningful and productive collaborations between investigators. In an effort to promote enhanced research capacity within the DMD field, the FY24 CTRA includes an option for an Early-Career Partnering Principal Investigator (PI). The Partnering PI Option is structured to accommodate two PIs. One PI will be identified as the Initiating PI and will be responsible for the majority of the administrative tasks associated with application submission. The Early-Career PI will be identified as the Partnering PI. Both PIs should contribute significantly to the development and execution of the proposed research project. If recommended for funding, each PI will be named on separate awards to the recipient organization(s). Each award will be subject to separate reporting, regulatory, and administrative requirements. For individual submission requirements for the Initiating and Partnering PI, refer to Section II.D.2, Content and Form of the Application Submission.The FY24 DMDRP CTRA offers two funding levels (refer to Section II.D.5 Funding Restrictions). Only one funding level category may be chosen per application, and the choice of application category is at the discretion of the applicant. The following are generalized descriptions of the scope of the research appropriate for each funding level:Funding Level 1: Funding Level 1 is intended to support smaller, less complex preclinical and/or clinical research. Pilot clinical trials are allowed. The proposal/applications direct costs budgeted for the entire period of performance should not exceed $650,000.Funding Level 2: Funding Level 2 is intended to support larger, more complex preclinical and/or clinical research. Pilot clinical trials are allowed. The proposal/applications direct costs budgeted for the entire period of performance should not exceed $1.35M.Additionally, both funding levels will support an Early-Career Partnering PI Option at the same maximum direct costs and periods of performance, respectively.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Both pilot clinical trials and clinical research are permitted under this mechanism.A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.All investigators applying to FY24 DMDRP funding opportunities and conducting clinical research are encouraged to consult the Strategies to Promote Diversity in Muscular Dystrophy Research Participation developed by the MDCC.

This funding opportunity provides financial support for the design and operation of a facility that extracts and refines rare earth elements from unconventional sources, aimed at strengthening domestic supply chains and reducing reliance on foreign materials.

This funding opportunity provides $100,000 to established for-profit businesses in Cook County, Illinois, to support their growth through capital investments in workforce expansion, equipment, and facility upgrades.

Project is to increase the capacity of partner countries to develop, adopt, and implement legal frameworks that protect individual data privacy while educating key stakeholders and enabling trusted cross-border data flows and digital trade.

This funding opportunity supports Arizona-based institutions conducting clinical research on ibogaine's potential therapeutic uses for neurological diseases, encouraging collaboration among academic, nonprofit, and private sectors.

This funding supports Southern nonprofit organizations and government entities in enhancing their artistic programming and professional development through travel and training opportunities.

The Alaska Community Foundation (ACF) is seeking applications for its Kodiak Community Foundation Grants program, targeting charitable organizations and programs within the Kodiak Archipelago Area. This grant opportunity aligns with the ACF's broader mission to support diverse community needs, with a focus on local impact in the Kodiak region. The program aims to address a wide range of needs, ensuring that funding contributes to the well-being and development of the community. The target beneficiaries of these grants are charitable organizations and programs operating in the Kodiak Archipelago. The impact goals are broad, encompassing health and wellness, education, outdoor activities, arts and culture, and community development. The foundation's strategic priority is to empower local initiatives that directly benefit the residents of the Kodiak area, reflecting a theory of change that grassroots efforts are crucial for sustainable community growth. The program prioritizes projects that address a broad spectrum of community needs. While specific outcomes are not rigidly defined beyond these categories, the expectation is that funded projects will contribute to an improved quality of life, enhanced community resources, and increased opportunities for residents in the aforementioned areas. Measurable results would likely be defined by individual grant recipients based on their specific project goals, within the broader framework of the foundation's focus areas. Funding information indicates average awards range from $1,000 to $3,000, with a potential for higher or lower amounts, and grant projects must be completed within one year of the award. The eligibility criteria emphasize support for 501(c)(3) public charitable organizations, faith-based organizations providing social services, federally recognized Tribes or Tribal non-profit organizations, and city or borough governments. This structured approach ensures that resources are directed towards credible and impactful entities capable of delivering on the grant's objectives.

This program provides financial assistance to small, independently owned businesses in Wakefield, Massachusetts, to help them enhance their digital marketing efforts and expand their online presence.

This grant provides funding for research and development projects aimed at improving the equipment and support systems for U.S. Army soldiers, focusing on enhancing their survivability, mobility, and overall effectiveness in the field.

This funding opportunity supports collaborative research projects that aim to develop clinical applications addressing health issues related to military toxic exposures, targeting independent researchers and their partners.