Grants for Nonprofits - Science and Technology

This funding opportunity supports small research projects that explore how immigrants integrate into American society, focusing on their legal status and economic advancement.

The Minnesota Pollution Control Agency is offering a grant of over $1 million to public, private, and nonprofit owners of heavy-duty diesel vehicles in Minnesota to replace their old vehicles with new, cleaner models, aiming to reduce diesel emissions and improve air quality.

This funding opportunity is designed to support domestic industrial facilities in recovering critical minerals and materials from byproducts, enhancing the U.S. supply chain and reducing reliance on foreign sources.

CJI’s Leadership Circle is soliciting proposals from grassroots organizations led by formerly incarcerated and directly impacted individuals. The program aims to transform and reimagine the U.S. criminal legal system by building alternative community-based solutions and organizing to prevent the criminalization of marginalized identities and communities. This initiative directly aligns with CJI's mission to support meaningful, transformative, and systemic change within the criminal legal system, empowering future leaders who have often experienced incarceration themselves. The foundation's strategic priority is to support movement-building organizing that creates a new world, a "world they demand NOW." The target beneficiaries are formerly incarcerated individuals and directly impacted people, including primary family members, as well as marginalized groups within their communities (e.g., poor, houseless, young, elders, queer, trans, people with mental illness, people with disabilities). The program's impact goals include ending mass criminalization and incarceration, creating safe and healthy communities that do not rely on arrest and incarceration, and re-establishing rights and access for those formerly incarcerated or newly criminalized. The Leadership Circle's theory of change emphasizes shared authority among donors and community organizers, many of whom have lived experience with incarceration, to drive systemic change. The program prioritizes several key areas. This includes building alternatives to traditional carceral systems, investing in approaches that end mass criminalization, creating policies to reform and dismantle repressive legal systems, and uplifting the leadership and experience of those affected by the criminal legal system. Other focuses include re-establishing rights for formerly incarcerated individuals, promoting transformative and restorative justice, and supporting culturally appropriate healing programs connected to the criminal justice movement. CJI also has specific funding preferences for organizations led by formerly incarcerated individuals, groups operating in difficult political environments, those developing new leaders from marginalized backgrounds, and work addressing discrimination against incarcerated or detained people, particularly in the South, Indian country, and other rural areas. Expected outcomes and measurable results include the development of community-based interventions, changes in policies and institutions (like parole and probation), and a demonstrable commitment to systems change through organizing. The program seeks to empower new leaders, particularly from marginalized communities, and foster innovative collaborations among diverse organizations. While specific quantitative metrics are not provided in the description, the emphasis on "movement-building organizing" and "achieving systems change" suggests that the success will be measured by the demonstrable impact on criminal legal system reform and the empowerment of affected communities. CJI is particularly committed to supporting smaller, emerging organizations with budgets of $1 million or less, indicating a focus on grassroots impact and capacity building.

The Confronting Hazards, Impacts and Risks for a Resilient Planet Program (CHIRRP) invites projects focusing on innovative and transformative research that advances Earth system hazard knowledge and risk mitigation in partnership with affected communities. Hazards compounded by changing climates, rising populations, expanding demands for resources, aging infrastructure, and increasing reliance on technology are putting our economy, well-being, and national security at risk. Researchers, academics, and community leaders will work together to develop community-driven research questions and actionable, science-based solutions that increase community resilience now and in the future. CHIRRP projects are expected to advance understanding, forecasting and/or prediction of future Earth system hazards and risks, engage communities in development of research questions and approaches, and produce actionable, science-based solution pathways for adaptation methodologies, products, and services. CHIRRP projects may evaluate a single or system of cascading hazards, impacts, and risks at a local, regional, or global scale through the lens of transformative earth system science research. Competitive projects will engage community partners at all stages of a project from development to implementation. CHIRRP currently supports planning, conference, RCNs, EAGER, and RAISE proposals that support development of community partnerships, provide training for effective community engagement, catalyze ideas, and/or support the initial conceptualization, planning and collaboration activities aimed at formulating new and sound plans for future large-scale projects. CHIRRP Elements CHIRRP projects will demonstrate convergence of three essential elements: (1) Equitable Community Partnerships; (2) an Earth System Science approach to advance knowledge of hazards, impacts, and risks and (3) Actionable Solutions that increase resilience. The initiative seeks solutions to existing as well as next-generation Earth system hazards1. Build Equitable Community Partnerships: CHIRRP projects will serve a community and equitably co-produce project research questions and solutions. CHIRRP teams will bring together community members with direct knowledge of hazard impacts and community priorities and researchers with expertise in the natural and human dimensions of the Earth system. Partners may include, but are not limited to, local governments, Tribal Nations, civil society organizations, youth groups, and non-government organizations (NGOs). Robust partnerships are responsive to community priorities, may involve a social science component, and lead to actionable solutions that increase community resilience. Advance Earth System Science: Generating practical and foundational knowledge on many of the nation's most urgent challenges requires a systems approach to understand the highly interdependent and complex natural and human components of the Earth system. CHIRRP projects will innovate and advance Earth System Science approaches that explore dynamic interactions and couplings among natural and social processes that affect Earths capacity to sustain the well-being of communities, infrastructure, and national security.Evaluate Actionable Science-Based Solutions: CHIRRP deliverables include co-produced innovative, science-based actionable solution pathways that mitigate future hazards, impacts, and risks. Multiple solutions may exist, and new solutions may emerge in the future. CHIRRP projects will inform pathways to resilience through evaluation of different solutions informed by the advancement of earth systems knowledge delivered from the project. An understanding of risk, vulnerability and resilience necessarily entails an understanding of relevant social dynamics including methods and analysis to identify how the impacts of hazards may disproportionately affect specific segments of a community or region. Solutions should be responsive to community priorities, including objectives such as reducing Earth system hazard related risk, increasing resilience, and advancing equity.1National Academies of Sciences, Engineering, and Medicine. 2022. Next Generation Earth Systems Science at the National Science Foundation. Washington, DC: The National Academies Press. https://doi.org/10.17226/26042 [placeholder to add URL link in the text]. [Placeholder to insert CHIRRP image here.]

This funding opportunity provides financial support to arts organizations of color in New England with annual expenses under $500,000, helping them sustain and expand their cultural programming and community engagement.

This grant provides funding to nonprofit organizations and government entities that aim to improve the quality of life for residents in Kossuth County, Iowa, through various community-focused projects.

The DoD Bone Marrow Failure, Idea Development Award is a funding opportunity aimed at supporting innovative and scientifically sound research ideas that contribute to understanding and curing bone marrow failure diseases, with a particular emphasis on hypothesis-driven studies linked to clinical trials, open to both established and early-career investigators.

The Ohio Animal Foundation is currently accepting applications for its grant program, which aims to support animal welfare initiatives across the state. While the foundation's overarching mission isn't explicitly detailed, the focus of this grant program on rescue and shelter services, as well as wildlife protection, education, and rehabilitation, strongly indicates an alignment with improving the lives of animals and protecting wildlife within Ohio. The target beneficiaries for this grant program are Ohio-based 501(c)3 nonprofit organizations that are in good standing, specifically those involved in animal rescue, shelter services, or wildlife programs. The program intends to support services for domestic, companion, and farm animals, as well as feral and community cats. It also extends its reach to wildlife protection, education, and rehabilitation efforts. The impact goals are to provide essential funding to these organizations, enabling them to continue their vital work in animal care and protection. The priorities and focuses of the grant program are clearly defined. A significant emphasis is placed on "Rescue and Shelter Services," which includes a broad spectrum of animal care, from domestic animals to feral cat programs. Additionally, "Wildlife Protection, Education and Rehabilitation Programs" are a key area of interest, highlighting the foundation's commitment to both domesticated and wild animal populations. The typical grant range of $250-$500 suggests a strategy of providing smaller, impactful grants to a wider array of organizations. While specific expected outcomes and measurable results are not explicitly stated, it can be inferred that the foundation aims to see improvements in animal welfare metrics such as increased adoptions, successful rescue operations, effective rehabilitation of injured wildlife, and enhanced public education on animal care and protection. The modest grant size suggests a focus on supporting operational costs or specific, smaller-scale projects that can demonstrate tangible benefits within these fields. The foundation's strategic priorities and theory of change appear to center on empowering local Ohio-based nonprofits to directly address animal welfare needs. By providing financial assistance to established 501(c)3 organizations, the Ohio Animal Foundation likely believes that it can most effectively leverage existing infrastructure and expertise to achieve its goals. The exclusion of funding for individuals further supports this approach, focusing resources on organizations with a proven capacity for impact.

This funding opportunity provides financial support to non-profit organizations and municipalities in Salem County, New Jersey, for special arts projects, general operating expenses, or technical assistance to enhance local arts initiatives.

This grant provides funding to early-career researchers dedicated to innovative breast cancer research, emphasizing transformative approaches and collaboration with breast cancer survivors.

This program provides financial support and service credits to U.S.-based nonprofits to enhance their operational capabilities and strategic planning efforts.

This funding opportunity supports organizations in Greater Philadelphia that provide engaging arts education programs for young people aged 5 to 18, fostering creativity and personal growth through partnerships with skilled teaching artists.

The NIST Hollings Manufacturing Extension Partnership (MEP), authorized by 15 U.S.C. 278k, is seeking applications from eligible applicants to enter into a cooperative agreement to operate an MEP Center in the State of Florida. The MEP Center will provide manufacturing extension services to small and mid-sized manufacturers (SMMs) in the State of Florida. The MEP Center will become part of the MEP National Network, which consists of 51 MEP Centers located in every State and Puerto Rico, and over 1,440 trusted advisors and experts at approximately 460 MEP service locations.

The McKean County Community Foundation (MCCF) awards grants through its McKean County Community Development Fund, an unrestricted fund aimed at enhancing the economic and community well-being of McKean County. This initiative aligns directly with the MCCF's mission to support community development, ensuring that vital resources are channeled to areas that will foster significant growth and improvement within the region. The grants are designed to be a catalyst for positive change, focusing on broad community benefit rather than specific individual needs. The primary beneficiaries of this grant program are nonprofit agencies operating within McKean County that are dedicated to community development initiatives. The overarching impact goal is to strengthen the economic and social fabric of the county by funding projects that address critical community needs and foster sustainable growth. While specific target populations within the county are not explicitly detailed, the focus is on initiatives that benefit the community as a whole, thereby elevating the quality of life for all residents. The MCCF prioritizes innovative projects that demonstrate a clear plan for long-term sustainability. The grants are not intended to cover an agency's direct operating expenses but rather to enhance existing programs or support the development of new, impactful initiatives. This strategic focus ensures that funding is used to build capacity and create lasting solutions, rather than simply maintaining the status quo. The foundation's theory of change emphasizes investment in creative solutions that have the potential for enduring community benefit. Expected outcomes include the successful implementation of innovative community development projects that contribute to the economic vitality and overall well-being of McKean County. While specific measurable results are not detailed in the provided information, the emphasis on innovation and sustainability suggests that successful projects would demonstrate tangible improvements in community indicators relevant to economic and social development. Approximately $10,000 is available this year, with a maximum grant request of $2,000 per applicant, indicating a strategy to support multiple smaller, impactful projects across the county.

The Rock Charitable Fund, administered by the Northern New York Community Foundation, is currently accepting applications for grants ranging from $100,000 to $500,000. This grant program aligns with the foundation's mission to support the well-being and historical preservation within St. Lawrence County, New York. The fund emphasizes projects that address existing structures and elements, as well as providing technical assistance and planning support, indicating a strategic priority on sustainable development and preservation rather than new construction or significant alterations to historic properties. The primary beneficiaries of the Rock Charitable Fund include 501(c)(3) charitable organizations, churches, houses of worship, cemeteries, and government entities. The fund targets projects that contribute to the maintenance and preservation of these institutions and places of historical significance within St. Lawrence County. Additionally, the fund aims to benefit and/or assist Veterans of the United States Military residing in St. Lawrence County by addressing their medical and recreational needs through qualified organizations. The impact goals are centered on enhancing community resources, preserving local heritage, and improving the quality of life for Veterans. The program's priorities and focus areas are clearly defined. For historical and religious properties, there's a strong preference for exterior projects that are publicly visible and accessible, though interior improvements may be considered. Peripheral or incidental projects are not desired. For cemeteries, support covers the property as a whole or aesthetically significant portions, explicitly excluding individual burial plots or monuments without special justification. For Veterans, grants are awarded to qualified organizations serving them, not directly to individuals, and can support programs for medical and recreational needs. This structured approach highlights a theory of change that leverages established organizations to create broader community benefit and long-term impact. Expected outcomes include the successful preservation and maintenance of historically significant sites and religious institutions, ensuring their continued benefit to the public. For Veterans, the anticipated result is improved access to medical and recreational support, contributing to their overall well-being. Measurable results could include the number of structures preserved, the extent of public access improved, and the number of Veterans served by supported programs. The foundation's strategic priorities are evident in its commitment to tangible, community-focused projects that have a lasting positive effect on St. Lawrence County's heritage and its Veteran population.

This grant provides funding to eligible organizations that support community programs focused on health, basic needs, workforce development, and youth development for low-income families in Wayne and Holmes Counties, Ohio.

This program provides matching funds to small businesses in North Carolina that have received federal SBIR or STTR awards, helping them develop and commercialize innovative technologies.

The 2025 Arts & History Re-Grant Program, administered by the Cape May County Government in New Jersey, offers funding to support arts and history-related projects and ongoing programs within Cape May County. The program's mission aligns with fostering community engagement and increasing exposure to arts and history. It aims to support a diverse range of initiatives, from single events to sustained programming, ultimately enriching the cultural landscape of the county. The program targets organizations and groups located within Cape May County that are involved in arts or history. This includes civic organizations, social organizations, community theater groups, dance companies, museums, galleries, orchestras, and singing groups. The impact goals are to support and sustain arts and history projects, programs, and general operations, thereby enhancing cultural offerings and community participation in these areas. There are three distinct categories of funding: Special Project, General Programming Support (GPS), and General Operating Support (GOS). Special Project funding is for single, specific arts or history-related events. GPS supports major, ongoing arts programs with multiple events or activities throughout the year. GOS is designed for organizations whose primary charter is arts or history-related, providing general operating support to groups that consistently increase exposure to art/history in the community. The program prioritizes projects and programs that take place within Cape May County and, for General Operating Support, requires the applying organization to be located within the county. Expected outcomes include a more vibrant cultural scene in Cape May County, increased opportunities for residents to engage with arts and history, and the sustained operation of local arts and history organizations. Measurable results would involve the number and diversity of projects funded, the reach and attendance of programs, and the organizational stability of grant recipients. The strategic priorities revolve around making arts and history accessible, supporting the infrastructure of cultural organizations, and ensuring fiscal responsibility, particularly for General Operating Support grants. The program's theory of change posits that by providing targeted financial support, local cultural initiatives will thrive, leading to a more enriched and engaged community.

Maturing research ideas into clinical practice and patient benefit is at the heart of all CDMRP research programs. Despite significant investment, the gap between what is possible and what is achieved remains. Even after information, tools, and interventions have been successfully evaluated in their intended populations, the development of knowledge to support their broader dissemination and implementation has often remained outside the scope. The FY24 TBIPHRP HSRA intends to bridge the gap between research, practice, and policy by building real-world evidence on how interventions, clinical practices/guidelines, and policies can be deployed to targeted populations at the appropriate time.Research Scope: The FY24 HSRA will fund clinical research (including clinical trials). Preclinical and animal research are prohibited. Prospective or retrospective clinical research or clinical trials involving human subjects, human subject data/records, and human anatomical substances are allowed. Proposed clinical trials should include interventions, clinical practices/guidelines, and policies that are well-supported within the literature and in relevant patient population(s). This award may not be used to support studies requiring an exception from informed consent (EFIC).Key aspects of the FY24 TBIPHRP HSRA: Precision Medicine Approaches: When appropriate, the TBIPHRP encourages the use of precision medicine approaches. These tailored treatments deliver the right treatment at the right time while considering an individuals unique characteristics. Community-Based Participatory Research: The application must include Community-Based Participatory Research (CBPR) approaches in the development and execution of the clinical research/trial. CBPR approaches should be documented in Attachment 8. Preliminary data are required: Inclusion of preliminary data relevant to the proposed clinical research/trial is required. Untested novel interventions are discouraged: Novel interventions that have not been evaluated in the intended population(s) are discouraged. Applicants seeking funding for novel interventions should consider one of the other FY24 TBIPHRP announcements. Study Population: The application should demonstrate the availability of and access to a suitable patient population that will support a meaningful outcome for the study. The application should include a discussion of how accrual goals will be achieved, as well as the strategy for inclusion of women and minorities in the clinical trial appropriate to the objectives of the study. Studies utilizing human biospecimens or datasets that cannot be linked to a specific individual, gender, ethnicity, or race (typically classified as exempt from Inquiry Review Board [IRB] review) are exempt from this requirement. Clinical Trial Start Date: If applicable, the proposed clinical trial is expected to begin no later than 6 months after the award date. Intervention Availability: If applicable, the application should demonstrate the documented availability of and access to the drug/compound, device, and/or other materials needed, as appropriate, for the proposed duration of the study.The FY24 HSRA applications may include (not all inclusive): Research that accelerates the uptake and implementation of evidence-based research into clinical practice. Comparative effectiveness research comparing the benefits and harms of emerging or established interventions and strategies to prevent, diagnose, treat, and monitor health conditions in real-world settings. Development and evaluation of strategies to overcome barriers to the adoption, adaptation, integration, scale-up, and sustainability of evidence-based interventions, tools, policies, and guidelines. Analysis of existing data or resources to inform clinical practice. Modification of established clinical tools for their intended population or environment. Analysis of existing clinical tools to maximize patient-relevant outcomes. Identification and analysis of the circumstances that create a need to stop or reduce (de-implement) the use of interventions, tools, policies, and guidelines that are ineffective, unproven, low-value, or harmful are within scope. Analysis of TBI and/or psychological health outcomes associated with the implementation of clinical practice guidelines, evidence-based practices, and process improvements.Early-Career Investigator Partnering Option: The FY24 TBIPHRP HSRA includes an Early-Career Investigator Partnering Option that is structured to accommodate two Principal Investigators (PIs), one of whom is an Early-Career Investigator. The combined direct costs budgeted for the entire period of performance in the applications of the Initiating PI and Partnering PI should not exceed $2.5M. The PIs may have experience in similar or disparate scientific disciplines, but each PI is expected to bring distinct contributions to the application. One PI will be identified as the Initiating PI and will be responsible for most of the administrative tasks associated with application submission. The other investigator will be the Partnering PI. At least one of the Initiating or Partnering PIs must be an Early-Career Investigator. The intent is not to create mentor-mentee arrangement. Both PIs should contribute significantly to the development of the proposed research project, including the Project Narrative, Statement of Work (SOW), and other required components. The application is expected to describe how the PIs unique experience/expertise combined as a partnership will better address the research question, how the unique experience/expertise that each individual brings to the application is critical for the research strategy and completion of the SOW, and why the work should be done together rather than through separate efforts. If recommended for funding, each PI will be named to an individual award within the recipient organization(s). For individual FY24 TBIPHRP HSRA submission requirements for the Initiating and Partnering PI, refer to S Section II.D.2, Content and Form of the Application Submission.A clinical trial is defined in 45 CFR 46.102 as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials. For more information, a Human Subject Resource Document is provided at https://cdmrp.health.mil/pubs/pdf/Human%20Subjects%20Resource%20Document.pdf.Clinical trials may be designed to evaluate pharmacologic agents (drugs or biologics), diagnostics, devices, therapies, clinical guidance, behavioral interventions, emerging approaches and technologies, and/or new indications for products currently U.S. Food and Drug Administration (FDA)-approved or -cleared. Interventions that are not FDA-regulated (or international equivalent) are within scope but the regulatory status must be documented in Attachment 12, Regulatory Strategy.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.Multi-Institutional Clinical Research/Trials: As of January 20, 2020, U.S. institutions engaged in non-exempt cooperative research must rely on a single IRB to review and approve the portion of the research conducted at domestic sites (45 CFR 46.114(b)). If the proposed, non-exempt research involves more than one U.S.-based institution, a written plan for single IRB review arrangements must be provided at the time of application submission or award negotiation. The lead institution responsible for developing the master protocol and master consent form should be identified and should be the single point of contact for regulatory submissions and requirements.Communication and data transfer between or among the collaborating institutions, as well as how specimens and/or imaging products obtained during the study will be handled, should be included in the appropriate sections of the application. A separate intellectual and material property plan agreed on by all participating institutions is also required for multi-institutional clinical research/trials.Relevance to Military Health: Relevance to the health care needs of Service Members, their Families, and Veterans is a key feature of this award. Investigators are encouraged to consider the following characteristics as examples of how a project may demonstrate relevance to military health: Explanation of how the project addresses an aspect of psychological health conditions and/or TBI that has direct relevance to the health and/or readiness of Service Members, their Families, and Veterans. Description of how the knowledge, information, products, or technologies gained from the proposed research could be implemented in a dual-use capacity to benefit the civilian population and also address a military need. Use of military or Veteran populations, samples, or datasets in the proposed research, if appropriate.Awards supported with FY24 funds will be made no later than September 30, 2025.The CDMRP expects to allot approximately $15.5M to fund approximately four HSRA applications. Funding of applications received is contingent upon the availability of federal funds for this program, the number of applications received, the quality and merit of the applications as evaluated by peer and programmatic review, and the requirements of the government. Funds to be obligated on any award resulting from this funding opportunity will be available for use for a limited time period based on the fiscal year of the funds. It is anticipated that awards made from this FY24 funding opportunity will be funded with FY24 funds, which will expire for use on September 30, 2030.