Grants for City or township governments - Federal

This cooperative agreement establishes the Hepatitis C Training and Implementation Center (HC-TIC) Network, which aims to accelerate the integration of hepatitis C prevention, testing, care coordination, and treatment interventions (program implementation) in priority high-impact settings through training and implementation TA. This cooperative agreement will improve and sustain the quality, availability, and reach of hepatitis C prevention and care activities in priority high-impact settings. Protection of public health and safety through the control and prevention of disease, injury, and disability in the U.S. and worldwide with attention to infectious disease, food borne pathogens, environmental health, occupational safety and health, health promotion, injury prevention and educational activities.

This funding opportunity provides financial and technical assistance to partners for projects that restore aquatic connectivity and improve fish passage in rivers, floodplains, and coastal habitats, benefiting ecosystems and local communities.

The Public Diplomacy Section (PD) of the U.S. Embassy in Luxembourg announces an open competition for organizations to submit applications to carry out programs strengthening bilateral ties between the United States and Luxembourg on Engaging Students in English. The U.S. Embassy Luxembourg invites proposals from non-governmental organizations, think tanks, government institutions, academic institutions, and individuals for programs strengthening the bilateral ties between the United States and Luxembourg and Engaging Students in English, including, but not limited to: Programs focused on strengthening specific English language skills or professional English capacity of students, such as public-speaking, debate, theater/drama Programs that enhance and promote the English-teaching profession and community, such as trainings, workshops, conferences, or presentations for English educators in Luxembourg. English-language programs for underprivileged groups including but not limited to patrons of organizations, such as shelters for refugees, women, abuse victims or childrens organizations. Educational programs such as English language camps, academic competitions, international exchanges, conferences, workshops, courses, exhibits, hackathons, online projects, or performances. Projects that share American best practices in English-language education by bringing U.S. experts to engage with students and teachers in Luxembourg. All programs must engage Luxembourg audiences. All programs must include a U.S. element or connection with U.S. experts that will promote increased understanding of U.S. policy and perspectives. Any speaker paid with grant funding must hold U.S. citizenship. Please review the complete NOFO on the Funding Opportunities page on our website: https://lu.usembassy.gov/grants-program/ or in the related documents tab on the announcement on grants.gov to find more information on how to submit a Statement of Interest.

This funding opportunity supports researchers and organizations developing innovative therapeutic leads for diseases related to diabetes, digestive, and kidney health, focusing on early-stage preclinical validation to advance potential treatments not currently pursued by major pharmaceutical companies.

This funding opportunity provides financial support to non-profit organizations and governmental institutions in Uruguay and the U.S. to implement projects that strengthen economic development, democracy, and security, fostering collaboration between American and Uruguayan entities.

The National Cancer Institute is offering funding for research projects aimed at validating the effectiveness of various markers and assays in cancer detection, diagnosis, treatment, and prevention, with a focus on developing these into clinical assays and ensuring their performance across multiple laboratories.

This funding opportunity supports researchers in developing innovative, safe, and noninvasive methods to assess the placenta's development and function throughout pregnancy, with the goal of improving maternal and fetal health outcomes.

This funding opportunity supports clinical research to explore and validate new non-invasive brain stimulation techniques for treating substance use disorders, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

Reissue of PA-18-350. The NIMH Exploratory/Developmental Grant program supports exploratory and high-risk research projects that fall within the NIMH mission by providing support for the early and conceptual stages of these projects. These studies may involve considerable risk but may lead to a breakthrough or to the development of novel techniques, agents, methods, measures, models, or strategies, or to the generation of pilot or feasibility data. The preliminary work from these studies could lead to a major impact on biomedical, behavioral, or clinical mental health research, or on the delivery of mental health care.

This program provides financial and technical support to private landowners and communities for restoring and conserving fish and wildlife habitats on private lands, benefiting endangered species and promoting biodiversity.

The "Coordinating Center for Type 1 Diabetes TrialNet" grant aims to fund the TrialNet Coordinating Center, which conducts research, trials, and studies to prevent the progression of type 1 diabetes and preserve insulin production, while also managing data, samples, and network operations, and promoting diverse perspectives in its work.

This notice of funding opportunity (NOFO) will support projects proposing mechanistic studies that will transform our understanding of polysubstance use in addiction. These hypothesis-based, exploratory projects may investigate mechanisms of polysubstance use at the behavioral, cognitive, cellular, circuit, genetic, epigenetic, pharmacological and/or computational levels. Research on substance use disorders (SUDs) has primarily focused on individual substances although polysubstance use is prevalent. Polysubstance use is the use of more than one addictive substance within a defined interval; the use may be sequential (use of multiple substances on separate occasions), or concurrent/simultaneous. Limiting studies to an individual addictive substance overlooks potential interactions between substances and could influence the translational potential of preclinical research findings. Results from several studies have demonstrated that the use of multiple addictive substances produces pharmacokinetic and behavioral profiles that are distinct from those produced by a single substance. Despite this recognition, little is known about the precise pharmacological mechanisms and interactions that may contribute to such outcomes, or co-morbidities resulting from co-use. There is also a significant lack in our understanding of how the activity of discrete cells, genes, circuits, expression of receptors, ion channels, intrinsic excitability or signaling mechanisms in the reward systems synergize when exposed to distinct classes of drugs simultaneously or sequentially. Even less is known about these mechanisms in brain regions and circuits that underlie negative reinforcement, or how neurotransmitters, neuromodulators or stress interact within these circuits to contribute to the behavioral and pharmacological profiles observed following polysubstance use. In addition, there is a need for behavioral models of polysubstance use that have translational potential. Research Objectives: The National Institute on Drug Abuse (NIDA) seeks to stimulate innovative research that will transform our understanding of the basic mechanisms that underlie polysubstance use in addiction. These studies will investigate novel neurobiological, pharmacological and/or behavioral mechanisms underlying the biobehavioral outcomes of polysubstance use. Research areas and questions of programmatic interest include, but are not limited to: Identification and/or characterization of molecules, genes, cells (including non-neuronal cells), neural pathways, circuits, receptors, ion channels, intrinsic excitability, pharmacological and signaling mechanisms mediating the effects of polysubstance use. Mechanisms underlying the association of early adolescent polysubstance use with SUD’s in adulthood. Sex differences in the development and trajectory of polysubstance use. What are the roles of organizational and activational effects of sex steroids on discrete brain regions and neural circuits, and how is this altered with exposure to polysubstance use? What are the developmental determinants? Are there developmental windows during which polysubstance use would be facilitated? What are the pharmacologic, pharmacokinetic and pharmacodynamic interactions that can impact toxicity, or the SUD trajectory? How do environmental factors interact with brain circuits to influence the development and trajectory of SUDs involving polysubstance use? How does stress interact with brain circuits to influence the development and trajectory of SUDs involving polysubstance use? Are there neurobehavioral risk phenotypes for progression to polysubstance use? What are the neurocognitive and neurobehavioral changes that occur through experience with different patterns of polysubstance use? Applications Not Responsive to this Notice of Funding Opportunity (NOFO) The following types of studies are not responsive to this NOFO and will not be reviewed: The major goal of the project is not targeted at delineating the basic mechanisms underlying polysubstance use in addiction. Projects limited exclusively to the phenomenology of polysubstance use, consequences of polysubstance use, or those focused exclusively on the development of tools or animal models. Projects that do not focus on combinations of two or more addictive substances with well-justified translational and public health relevance. Projects that do not include a psychostimulant, opioid, or cannabinoid in the polysubstance combination. Alcohol may be included in the polysubstance combination. Research that does not pertain to at least one of the stages of the substance use trajectory, including, but not limited to initiation, escalation, withdrawal and/or relapse. Other application considerations: Collaborative research teams to foster the sharing of conceptual and/or technical expertise are strongly encouraged. Applicants using animal models are encouraged to use models reflective of chronic and voluntary drug intake. Preliminary data are not required but may be included if available. In the absence of preliminary data, a strong premise should be provided for testing a novel hypothesis based upon the scientific literature as well as evidence of the team’s ability to carry out the proposed studies through published or technical preliminary data.

The Administration for Children and Families (ACF); Administration on Children, Youth and Families (ACYF); Family and Youth Services Bureau (FYSB) supports organizations and communities that work every day to end youth homelessness and adolescent pregnancy. FYSBs Division of Runaway and Homeless Youth (RHY) is accepting applications for the RHY Prevention Demonstration Program (RHY-PDP). RHY-PDP supports the design and delivery of community-based demonstration initiatives to prevent youth from experiencing homelessness. Through the development and coordination of partnerships with youth and young adult service providers, community organizations, and private and public agencies, the RHY-PDP will 1) identify young people at risk of experiencing homelessness; 2) design and develop a comprehensive community-based prevention plan to prevent youth homelessness; and 3) implement robust, holistic prevention services tailored for youth and young adults to respond to the diverse needs of youth who are at risk of homelessness and their families.

The purpose of the RRTCs, which are funded through the Disability and Rehabilitation Research Projects and Centers Program, is to achieve the goals of, and improve the effectiveness of, services authorized under the Rehabilitation Act through well-designed research, training, technical assistance, and dissemination activities in important topical areas as specified by NIDILRR. These activities are designed to benefit people with disabilities, family members, rehabilitation service providers, policymakers and other research stakeholders. The purpose of this particular RRTC is to conduct research, training, technical assistance, and related activities to contribute to improved health and function among people with physical disabilities. NIDILRR plans to make one grant under this opportunity. The grant will have a 60-month project period, with five 12-month budget periods.

With this solicitation, BJA seeks to support the purchase and lease of body-worn cameras (BWCs) by publicly funded law enforcement and corrections agencies as part of comprehensive BWC programs guided by sound policy and broad stakeholder input. In addition, the solicitation seeks to support demonstration projects that advance digital evidence management, leveraging BWC digital footage to promote evidence-based and procedurally just practices in agencies with established BWC programs.

Computational fluid dynamics (CFD) has played a crucial role in providing an alternative bioequivalence (BE) approach for generic orally inhaled drug products (OIDPs), in addition to comparative clinical endpoint or pharmacodynamic BE studies, as a relatively cost- and time-efficient complement to benchtop and clinical experiments that has been widely used in developing and assessing generic inhaler devices. However, despite the advances in the power of modern computers, there are still some bottlenecks in using CFD due to computational time, limited grid resolution, pre- and post-processing of large simulation data sets, model parameter estimations, and uncertainty quantifications. Machine learning (ML) has been gaining more attention as a potential tool to alleviate such limitations that arise in CFD. The purpose of this grant is to develop a methodology to integrate ML with CFD models of OIDPs to promote alternative BE studies to enhance and accelerate the development and approval of generic OIDPs.

This funding opportunity supports early-stage researchers in cancer control and population sciences to explore innovative ideas that can significantly advance cancer research and improve healthcare delivery.

The U.S. Fish and Wildlife Service (FWS or Service) is the premier government agency dedicated to the conservation, protection, and enhancement of fish, wildlife and plants, and their habitats. We are the only agency in the federal government whose primary responsibility is the conservation and management of these important natural resources for the American public. The U.S. Fish and Wildlife Services origins date back to 1871 when Congress established the U.S. Fish Commission to study the decrease in the nations food fishes and recommend ways to reverse that decline. The FWS is committed to building and retaining a diverse and inclusive workforce that reflects the ethic, age, socioeconomic and cultural backgrounds, and language diversity of contemporary America. The FWS operates a variety of programs that promote wildlife conservation and public land management under the Public Lands Corps Act (PLC) through engagement, employment, and education of our nations diverse youth and veterans. FWS programs operating under the Public Lands Corps Act have been designated as covered programs under Justice40 (Executive Order 14008). The FWS strives to meet the Federal Governments goal that 40 percent of the overall benefits of certain Federal Investments flow to disadvantaged communities that are marginalized, underserved, and overburdened by pollution. The categories of investment are: climate change, clean energy and energy efficiency, clean transit, affordable and sustainable housing, training and workforce development, remediation of reduction of legacy pollution, and the development of critical clean water and wastewater infrastructure. The Public Lands Corps (PLC) Program is authorized by Congress under Title 16 USC Sec. 1721-1726; Public Law 109-154, Public Lands Corps Healthy Forests Restoration Act of 2005 (amends the Public Lands Corps Act of 1993), and all subsequent amendments. Guidance authorizes U.S. Fish and Wildlife Service to (1) establish PLC Programs (2) certify participants who meet the PLC eligibility requirements for the PLC non-competitive hiring authority status, and (3) ensure consistent program standards throughout the FWS. The purpose of the FWS PLC Programs is to provide work and education opportunities for youth (defined as ages 16-30 inclusive, and up to age 35 for veterans) participants in the areas of natural and cultural resource conservation, development, and scientific research. Participants perform work on our nations public lands by providing additional, unique capacity designed to boost the impact of the FWS for the conservation and management of fish, wildlife, plants and their habitats for the American people. The PLC FWS Youth Corps Program allows the FWS to establish partnerships with Partner organizations (Partners), generally defined as qualified youth or conservation corps, using financial assistance/cooperative agreements or MOUs, to employ the next generation of conservationists in paid PLC projects and internships. Partners must be designated as an official member of the FWS Youth Corps in order to certify Participants. FWS Youth Corps application information is available in the attachments to this Notice of Funding Opportunity (NOFO). The purpose of this NOFO is not to establish new partnerships. See Full Announcement for additional information and application instructions. Unsolicited partnership applications or projects that are not collaboratively developed between an existing FWS Youth Corps member and the U.S. Fish and Wildlife Service will be returned as ineligible. ***Applicants seeking technical or financial assistance from a FWS PLC programs are requested to consult with a local FWS office BEFORE developing or submitting an application (see FWS Youth Program Contacts included in the Related Documents of this announcement or visit U.S. Fish and Wildlife Service (fws.gov) to locate a FWS office in your area. ***Unsolicited Partnership applications submitted through Grants.gov will be returned as ineligible. See Related Documents for application instructions for FWS Youth Corps.

This funding opportunity supports researchers conducting basic science studies to explore how sleep and circadian rhythms are connected to substance use disorders, aiming to improve understanding and treatment of these issues.

OJP is committed to advancing work that promotes civil rights and equity, increases access to justice, supports crime victims and individuals impacted by the justice system, strengthens community safety, protects the public from crime and evolving threats, and builds trust between law enforcement and the community. With this solicitation, BJA seeks to fund applications to the FY 2024 Paul Coverdell Forensic Science Improvement Grants Program Competitive (Coverdell Competitive Program) to improve forensic science and medical examiner/coroner services, including services provided by laboratories operated by states and units of local government. This program furthers the DOJs mission to uphold the rule of law, to keep our country safe, and to protect civil rights.