Grants for For profit organizations other than small businesses - Federal

The "Critical Facility Energy Resilience (CiFER)" grant aims to fund the development and commercial deployment of innovative energy storage technologies, specifically at sites with identified resiliency needs, to enhance their progress towards commercialization.

The United States Agency for International Development in Vietnam (USAID/Vietnam) is seeking applications for a Cooperative Agreement from qualified entities to implement the USAID Climate Resilient Agriculture in the Mekong Delta Activity. Eligibility for this award is not restricted. The authority for the NOFO is found in the Foreign Assistance Act of 1961, as amended. In June 2022, USAID/Vietnam and the Vietnamese Ministry for Agriculture and Rural Development (MARD) signed a Limited Scope Grant Agreement, entitled Climate Resilient Agriculture in the Mekong Delta. The Agreement lays out how USAID and MARD intend to collaborate to increase climate resilience, reduce methane emissions from the agriculture sector, increase sequestration of greenhouse gas emissions in the Mekong Delta, and protect biodiversity through four approaches: (1) expand low methane emission agricultural development; (2) build climate resilience for vulnerable communities; (3) promote nature-based solutions; and (4) develop climate-resilient and low-emission development policies. The purpose of the USAID Climate Resilient Agriculture in the Mekong Delta Activity is to support implementation of the Limited Scope Grant Agreement with MARD. The goal of the Activity is to advance low-emissions, climate-resilient agricultural livelihoods combined with biodiversity conservation to support carbon sequestration, healthy ecosystems, and resilience of vulnerable communities in the Mekong Delta. This Activity will build capacity of and develop tools for the related stakeholders at national and subnational level to help the most vulnerable communities in the Mekong Delta adapt to climate change impacts, protect and restore natural ecosystems, and reduce methane emission from agriculture practices. This Activity’s interventions will be implemented over a period of five years starting from the award date.The purpose of this Request for Information (RFI) is to gather inputs for an upcoming funding opportunity for the activity that aims to advance low-emissions, climate-resilient agricultural livelihoods combined with biodiversity conservation to support carbon sequestration, healthy ecosystems, and resilience of vulnerable communities in the Mekong Delta.

This grant provides funding and technical support to innovators and organizations developing sustainable solutions for reusing and repurposing end-of-life products, promoting a circular economy and reducing waste.

This funding opportunity supports organizations in coordinating research efforts to address multiple chronic diseases and reduce health disparities, particularly in underserved communities.

The United States is made up of regional systems comprising interdependent urban and rural systems and every community category between urban and rural. Urban systems and rural systems are interdependent for the provisioning of food, energy sources, water, other materials and natural resources, markets, manufactured goods, and medical resources. These systems are also connected by ecological processes that both influence and are influenced by human behavior. The vital interconnection of urban-rural systems underscores the critical need for the advancement of sustainable regional systems (SRS). The goal of this solicitation is to fund convergent research and education that will advance sustainable regional systems science, engineering, and education to facilitate the transformation of current regional systems to enhance sustainability. To further the advancement of SRS science, engineering, and education, NSF will support proposals for Sustainable Regional Systems Research Networks (SRS RNs). Sustainable regional systems are connected urban and rural systems that are transforming their structures and processes collaboratively with the goal of measurably and equitably advancing the well-being of people and the planet. The purpose of the SRS RNs competition is to develop and support interdisciplinary, multi-organizational teams working collaboratively to produce cutting-edge convergent research, education, and outreach that addresses grand challenges in sustainable regional systems. SRS RNs will study multiscale regional systems to further SRS science, engineering, and education. Key elements will include new data, methods, and models to understand interactions between natural, human-built, and social systems; improved understanding of interdependencies, mutual benefits, and trade-offs of different wellbeing outcomes for humans and the environment; new and generalizable theories of change relevant to SRS;theco-production of knowledge; andexploration of conceptsof social equity in sustainable regional systems across spatial and temporal scales. SRS RN outcomes will have the potential to inform societal actions for sustainability across urban systems and the connected rural communities that make up regional systems. Subject to availability of funds and quality of proposals, this SRS RN solicitation will support: SRS RN Awards.These awards will supportfundamental convergent research, education, and outreach that addressesengineering, chemistry, biology, geosciences, mathematics, statistics, environmental, data, computational, education, and social, behavioral, and economic sciences ofsustainable regional systems in partnerships thatmay embrace universities, colleges, federal, state, and local governments, tribal communities, non-governmental and international bodies, non-profit organizations, industry, practitioners, and other community groups. The award size is up to $15 million totalwith a duration of 5 years. SRS RNs will conduct innovative and pioneering fundamental research and education that is of a scale and complexity that would not be possible within a single organization, center, or through the normal collaborative modes of NSF research support in core programs.

This funding opportunity supports the development of innovative computational tools to analyze complex brain data, inviting a diverse range of researchers and organizations to enhance our understanding of neural circuits and their functions.

The DoD Peer Reviewed Cancer, Virtual Cancer Center Director Award is a funding opportunity for established cancer researchers to create and lead a virtual cancer center, which aims to foster collaboration, mentorship, and innovative research among early career investigators across different cancer disciplines, with a focus on convergent science and the development of collaborative seed projects.

This funding opportunity provides financial support to organizations that will mentor and enhance the operational capabilities of the Somalia National Army and the African Union mission, aiming to stabilize the region and improve security against extremist threats.

The Geothermal Resources’ Value in Implementing Decarbonization (GRID) FOA aims to advance the Biden-Harris Administration's goals for a carbon-pollution-free electricity sector by 2035 and a net-zero emissions economy by 2050. The program focuses on regional grid modeling studies to quantify geothermal power's potential contribution to a decarbonized grid. Eligible applicants must submit a Letter of Intent by July 24th, 2024, and full applications by September 9th, 2024. The program offers funding between $500,000 and $1,500,000, with an estimated total funding of approximately $7 million.

The Red Bluff Fish and Wildlife Office (RBFWO), Central Valley Project Improvement Act (CVPIA) Program is soliciting proposals for the completion of a Feasibility Study to assess potential solutions to increase available floodplain habitat in the lower Feather River corridor through Nelson Slough and contribute to improved quality of juvenile salmonid rearing habitat through increased production and availability of food resources. The project location is in the California Department of Fish and Wildlifes Feather River Wildlife Area Nelson Slough Unit. Scope of WorkThis award will provide funds for a work effort consisting of identification, development and feasibility of a floodplain connectivity solution in Nelson Slough primarily benefiting juvenile salmonids. This will include facilitating meetings with the Technical Advisory Committee, composing of members from United States Fish and Wildlife Service (USFWS), National Marine Fisheries Service, California Department of Fish and Wildlife (CDFW) and California Department of Water Resources (CDWR). The USFWS and Project Management Team intend to use information collected from this study to develop a future habitat restoration project at this site. The project tasks and applicant responsibilities are the following: Information gathering and site reconnaissance; Project Management;Data Collection and Evaluation; Develop a multi-dimensional hydrodynamic flow model to assess floodplain inundation frequencies; Develop a sediment transport model; Landowner access; Facilitate, plan, and provide notes from Technical Advisory Committee meetings; andDevelop juvenile salmonid habitat alternatives (i.e., restoring natural processes, side-channel creation through historic oxbow, floodplain connectivity, etc.).Project The CVPIA SIT and Core Team recommended increasing access to juvenile rearing habitat in lower Feather River and Sutter Bypass and identified it as a high priority for FY2020 (2019 Tech Memo). The project will continue to be funded for planning and analysis in FY2025 with potential construction and implementation in FY2026. The proposed project completes a feasibility study to develop and evaluate potential restoration actions at the Nelson Slough Wildlife Area Unit to increase the frequency with which floodplain habitat is inundated. The project would be located on CDFW property at the confluence of the lower Feather River corridor and the Sutter Bypass near Nelson Slough.The project may include lowering and widening an existing slough within setback levees in the lower Feather River corridor downstream of Highway 99 and tying this into the Sutter Bypass; creating multiple swales within the area; and/or lowering the floodplain terrace. This would allow Feather River basin water to flow into the Sutter Bypass with much greater frequency than under current conditions, thereby connecting remnant floodplain (including an abandoned oxbow from the Feather River) in the lower Feather River corridor with existing floodplain in the Sutter Bypass. Nelson Slough, a 750-acre unit of the Feather River Wildlife Area, is adjacent to more than 3,500 acres of conservation properties along the Feather River and approximately 4,500 acres of conservation properties within the Sutter Bypass. The project could increase floodplain habitat available to Feather, Yuba, and Bear River salmonids by up to 1,000 acres or more under certain flow conditions. Additional floodplain inundation resulting from this project could provide rearing benefits to Sacramento River origin juvenile winter and spring-run Chinook salmon, juvenile Butte Creek spring-run Chinook salmon in the Sutter Bypass, Feather River basin spring-run Chinook salmon, as well as Central Valley steelhead and potentially juvenile green sturgeon. Currently, River Partners has been awarded funds through the CVPIA for improving salmon and steelhead juvenile rearing habitat through creation and restoration of up to five miles of side channels on the Lower Feather River adjacent to the Nelson Slough Wildlife Area Unit. This project could potentially be integrated with the River Partners Lower Feather River Side Channel Restoration Project. The Peterson, Coarse Resolution model Report, 2014 (DSM) suggests that supporting increasing juvenile Chinook size at emigration can be beneficial to the outcome of a greater number of returning adults. Post project monitoring may help improve or validate the hypothesis of the DSM. Supplemental InformationOutcome of the project would achieve the following goals: Increase accessible floodplain for Feather, Yuba, and Bear River salmonids by through increased access; Determination of the amount of accessible acres created at various flow ranges compared to existing conditions with various landscape changes;Reduce habitat fragmentation to improve rearing and emigration corridors; Increase and improve the quantity, quality, and diversity of riverine habitat, including floodplain rearing habitat for juvenile fish; Reduce predation impacts of non-native fish species in channel;Increase native riparian vegetation in restored habitat;Contribute to the recovery of federal and state listed fish populations; and Contribute to the Central Valley Project Improvement Act doubling goal for the Feather, Yuba, and Bear Rivers. Questions that will be addressed in the feasibility study are:Up-to-date topographic and bathymetric LiDAR or similar, relative to project area or any other areas of influence. Characterization of the hydrodynamics that would facilitate floodplain activation. Characterization of the hydrodynamics that would facilitate floodplain activation. Prioritize updating physical habitat characterization.Focus on (potential) instream system parameters (longitudinal profiles, cross section installation and revisiting those, etc.). Using a drone to map area pre-project, as well as post project. Assess:Flood conveyance, flood storage and inundation frequency and duration; Fluvial geomorphic processes;Aquatic and riparian habitat;Project costs;Land availability;Sedimentation;Excavated materials and spoil placements; andInfrastructure (i.e. utility pipelines, roadway bridge abutments).Pre-project assessments: This would include assessing hydrology and water quality, as well as biologic monitoring cataloging insect, bird, and other current animal habitat necessary to understand what the area is currently providing and serve as a baseline for assessing post project performance after implementation. Monitoring and evaluation are essential to determine whether restoration projects are implemented correctly and performing as expected so that we achieve the intended benefits. Wildlife Habitat Area Management Objectives: Current acreage of upland habitat shall not be decreased. Must not fragment current available upland habitat.Any side channels created would require a crossing for wildlife and staff to facilitate bird plants. Species of interest include quail, deer, turkey, pheasant, and multiple waterfowl. No restoration activity shall reduce the various hunting opportunities offered by CDFW on the Nelson Slough Unit (i.e., deer hunt season, waterfowl hunt season, quail hunt season, turkey fall hunt season, turkey spring hunt season, and pheasant hunt season). Awardee will coordinate closely with CDFW wildlife area staff to develop alternatives that do not impact these opportunities for the public. Considerations:Consider restoration design and implementation timing with DWR and Sutter County to complement their future levee improvement work at the Nelson Slough Unit and the surrounding reach of the Feather River and Sutter Bypass as described in the Riparian Restoration Plan for the Nelson Slough Unit (2009 River Partners) Department PriortiesThe mission of the U.S. Fish and Wildlife Service is working with others to conserve, protect, and enhance fish, wildlife, plants, and their habitats for the continuing benefit of the American people. Fish and Aquatic Conservation is an integral program within the U.S. Fish and Wildlife Service and supports the mission by working with partners to achieve benefits for aquatic species and their habitats. The U.S. Fish and Wildlife Service plays a key role in addressing the challenges identified in the Biden-Harris administrations priorities. https://www.fws.gov/initiative/directors-priorities Rebuilding the economy;Tackling climate change;Developing a wildlife conservation strategy for the 21st century;Combating Wildlife Trafficking.

The Department of State’s Office to Monitor and Combat Trafficking in Persons (TIP Office) announces an open competition for projects in support of the Child Protection Compact (CPC) Partnership between the United States and the Government of Nepal. The CPC Partnership is jointly developed and implemented by the United States and the Government of Nepal through a multi-year plan (approximately five years). The purpose of this CPC Partnership is to advance and strengthen the efforts of the Government of Nepal and civil society organizations in Nepal to combat forced child labor and child sex trafficking in a victim- 2 centered, coordinated, sustainable, and multi-sectoral approach to support an effective system of justice, prevention, and protection. This includes the implementation of a victim-centered prevention strategy that addresses targeted risk factors, promotes high-quality comprehensive victim protection, and investigates, prosecutes, and convicts perpetrators of child trafficking. The Ministry of Women, Children, and Senior Citizens (MoWCSC) is the primary focal point for the Government of Nepal under the CPC Partnership. However, the TIP Office anticipates close collaboration with additional government ministries and agencies at a federal, provincial, and local level including a full range of criminal-justice stakeholders. The full partnership will be posted online here: Child Protection Compact Partnerships - United States Department of State Nepal is the eighth CPC Partnership the US government has negotiated globally; the TIP Office has active CPC Partnerships in Peru, Mongolia, Colombia, and Cote d’Ivoire, and previous CPC Partnerships with the governments of Jamaica, the Philippines, and Ghana. More information is available at: . The purpose of this notice of funding opportunity is to advance and strengthen the efforts of the Government of Nepal and non-governmental organizations (NGOs) in Nepal to combat child trafficking in a victim-centered, coordinated, sustainable, and multi-sectoral approach to support an effective system of prevention, protection, prosecution, and partnership. Applicants are expected to propose activities that align with the goals and objectives outlined below from the U.S.-Nepal CPC Partnership text. Applicants should use the following illustrative activities to guide their proposals but are not expected to include every item listed: Objective 1 (Prevention): The Government of Nepal, particularly local government, coordinates with NGOs on child trafficking prevention efforts that are comprehensive and contextualized into local community child protection initiatives. Illustrative Activities: • Capacity Building o Strengthen and empower Local Coordination Committees on Human Trafficking; Train Child Welfare Officers to further identify and combat child trafficking; o Provide technical assistance to the MoWCSC on effective prevention strategies. • Awareness Raising o Engage schools and communities on action plans to identify and prevent child trafficking; o Engage families and communities about the risks of child trafficking among vulnerable communities; o Work with government and local communities to increase child registration for identification. • Community Interventions: o Targeted interventions for most at-risk populations; examples include but not limited to working with cash plus programs, community savings and loans cooperatives, financial inclusion strategies, vocational training, and alternative livelihoods; o Pilot or support community resilience programs to minimize the effects of disasters and climate change that exacerbate child trafficking risk factors. Objective 2 (Protection): The Government of Nepal supports child trafficking victims by providing accessible trauma-informed, victim-centered care, and supports NGOs to protect children throughout the country. Illustrative Activities: • Training and Curriculum Development o Expand social workers’ use of victim-centered and trauma-informed approaches; o Build capacity of local child-care centers with curriculum on minimum standards of care and sustainability plan. • Direct Victim Support o Enable organizations to provide protection services to child trafficking victims; o Identify and support protection services for male victims of trafficking, including shelter services for boys; 4 o Support reintegration efforts, including but not limited to vocational/ apprenticeship training, paying of school fees, and small business support. • Standard Operating Procedures o Create SOPs and/or handbooks to guide victim support in partnership with local committees; o Support implementation of identification guidelines with MoWCSC; o Develop repatriation procedures, SOPs, and guidelines for crossborder trafficking cases. • Capacity Building o Support the rollout of the Social Information Management System (SIMS) as a data collection tool and ensure it meets data sharing and case tracking needs; o Assist the “1098 hotline” for victims of human trafficking to be more responsive to victims and increase capacity to identify and serve trafficking victims. • Advocacy o Support pending legal code amendments that align laws with the Palermo Protocol; o Ensure civil society organizations are adequately resourced to provide needed victim services. Objective 3 (Prosecution): The Government of Nepal, including law enforcement, prosecutors and the judiciary, utilizes existing trafficking-specific legal frameworks to identify child trafficking victims, investigate cases, and prosecute and convict perpetrators of child trafficking in a child-friendly, victim-centered, and traumainformed manner. Illustrative Activities: • Training and Curriculum Development o Comprehensive (basic and advanced) training for justice-sector actors on the human trafficking law and how to utilize it during investigations, prosecutions, and convictions; o Comprehensive (basic and advanced) training for justice sector actors on victim-centered, trauma-informed, and child-friendly practices; o Training for law enforcement entities on trauma-informed and childfriendly techniques for gathering evidence and testimony from survivors of child trafficking; o Victim-centered training in the National Police Academy to combat human trafficking; o Curriculum for the National Judicial Academy focused on human trafficking laws, trauma-informed and child friendly practices, in coordination with NGOs o Methods to investigate and monitor online violence and cybercrimes. • Standard Operating Procedures o Child-friendly procedures for accompaniment of child trafficking victims and witnesses before the courts; o Child interview SOPs for police investigators and MoWCSC social workers; o Nationwide SOPs on victim identification, referral, and case management; o Support airport and border officers with resources for improved screening tools. • Establish New Practices o Digitized Court or “E-court” using video conferencing or video testimony likely connected with protection homes to support criminal cases; o Victim service units and victim-friendly court environments within the Supreme court and District courts; o Child-friendly spaces in local police offices, and/or other relevant locations; o Create child-friendly space guidelines that are adopted and used to train relevant staff; o Promote creation of a secure network and data collection system for criminal justice actors to share case details. • Advocacy o Expand judges’ use of current legal frameworks with innovative prosecution techniques such as victim compensation; o Promote appointment of an Office of the Special Rapporteur for Human Trafficking within the National Human Rights Council; o Create a cybercrime law from current cybercrime policy. 6 Objective 4 (Partnership): The Government of Nepal addresses child trafficking in a coordinated manner across all relevant ministries, local authorities and NGOs. Illustrative Activities: • Expand Alliances o Engage with private sector actors to raise awareness and prevent forced child labor in targeted industries; o Engage telecommunications companies to prevent online sexual exploitation of children; o Encourage parliamentary involvement on child protection issues; o Analyze the use of information technology to support child trafficking prevention and protection. • Information Sharing o Encourage information sharing across different data management systems, including the Missing Children and National Police databases. • National Frameworks o Review and support the Master Plan on Child Labor; o Support regional referral mechanisms and/or intergovernmental MOUs on trafficking with neighboring countries in the region; o Foster development and implementation of a National Action Plan. • Advocacy o Empower the National Coordination Committee on Human Trafficking; o Promote creation of a national budget line to combat child trafficking to ensure programs and relevant ministries are properly funded; o Facilitate sustainability planning to maintain CPC investments beyond the end of the agreement.

With this solicitation, OJJDP seeks to support targeted efforts to address youth violence in a school-based setting (K12th grade only). OJJDP seeks to increase school safety through the development and expansion of evidence-based and promising violence prevention and reduction programs and strategies to support school climate. Through this initiative, OJJDP expects applicants to utilize a collaborative approach between schools and community-based organizations (CBOs) to develop and implement these strategies.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in eliminating labor abuses and conditions of forced labor connected to cyber scam operations in Southeast Asia.

This funding opportunity supports research to develop and test behavioral sleep interventions for adolescents and young adults facing mental health challenges.

The National Cancer Institute intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications forresearch on the confluence of cancer stigma and HIV stigma in HIV-positive individuals diagnosed with cancer. This NOFO will utilize the R01 grant mechanism (clinical trial optional). Up to six (6) R01 awards are expected to be funded as part of the initiative. Research projects search project will advance the current understanding of the confluence of cancer stigma and HIV stigma among people with HIV (PWH) diagnosed with cancer; assess the impact of these two converging stigmas on cancer outcomes among PWH with cancer; leverage stigma reduction interventions at multiple levels to intervene on modifiable mechanisms of stigma that contribute to negative cancer outcomes among PWH with cancer; and promote research in diverse domestic and international contexts, focusing on regions in which the HIV-cancer burden is elevated. The NOFO is expected to be published in late Summer 2024 with an expected application due date in late Fall 2024. Details of a pre-application webinar will be announced after the publication of the NOFO. This Notice is being provided to allow sufficient time for potential applicants with relevant expertise and insights to consider applying for this NOFO. Potential applicants are encouraged to view the presentation of this initiative to the Joint Virtual Meeting of the NCI Board of Scientific Advisors and the National Cancer Advisory Board available at https://videocast.nih.gov/watch=54859 beginning at 3 hour, 39 minutes. Presentation slides are downloadable at: https://deainfo.nci.nih.gov/advisory/joint/0624/Vanderpool.pdf.

This grant provides funding for a Data Coordinating Center to support research projects focused on preventing stillbirth, emphasizing collaboration and equity in addressing disparities in vulnerable populations.

The "Research on Autism Spectrum Disorders" grant aims to fund projects that explore the causes, prevalence, diagnosis, and best service delivery methods for Autism Spectrum Disorders, with a focus on small, well-defined projects that can be completed within two years using limited resources.

NRCS is announcing the availability of Conservation Innovation Grants (CIG) State Program funding to stimulate the development and adoption of innovative conservation approaches and technologies. Applications are accepted from eligible entities (Section C) for projects carried out in the state of New York A total of up to $500,000 is available for the New York CIG competition in FY 2024. All non-Foreign, non-federal entities (NFE) and individuals are invited to apply, with the sole exception of federal agencies. Projects may be between one and three years in duration. The maximum award amount for a single award in FY 2024 is $500,000. For new users of Grants.gov, see Section D. of the full Notice of Funding Opportunity for information about steps required before submitting an application via Grants.gov. Completing all steps required to start an application can take a significant amount of time, plan accordingly. Key Dates Applicants must submit their applications via Grants.gov by 11:59 pm Eastern Time on May 10, 2024. [AF1] For technical issues with Grants.gov, contact Grants.gov Applicant Support at 1-800-518-4726 or [email protected]. Awarding agency staff cannot support applicants regarding Grants.gov accounts. For inquiries specific to the content of the NFO requirements, contact the federal awarding agency contact (section G of this NFO). Please limit questions to those regarding specific information contained in this NFO (such as dates, page numbers, clarification of discrepancies, etc.). Questions related to eligibility, or the merits of a specific proposal will not be addressed. Applicants are encouraged to visit the New York State CIG website to learn more about the CIG program. The agency anticipates making selections by June 10, 2024 and expects to execute awards by July 26, 2024. These dates are estimates and are subject to change.

The FY24 DMDRP IDA promotes new ideas that are still in the early stages of development and have the potential to yield impactful data and new avenues of investigation. This award supports conceptually innovative, high-risk/high-reward research that could lead to critical discoveries or major advancements that will accelerate progress in improving outcomes for individuals with DMD. Applications should include a well-formulated, testable hypothesis based on strong scientific rationale.New Investigators: The FY24 DMDRP IDA mechanism encourages applications from independent investigators in the early stages of their careers (i.e., within 10 years of their first faculty appointment or equivalent) or applications from established investigators new to DMD research.The New Investigator Early Stage category is designed to allow applicants early in their faculty appointments to compete for funding separately from established investigators.The New Investigator Transitioning category is designed to allow investigators in an area other than muscular dystrophy, at or above the level of Assistant Professor, seeking to transition to a career in DMD, thereby bringing their expertise to the field.Applications from New Investigators and Established Investigators will be peer and programmatically reviewed separately. Principal Investigators (PIs) using the New Investigator Early Stage category or New Investigator Transitioning category are strongly encouraged to strengthen their applications by collaborating with investigators experienced in DMD research and/or possessing other relevant expertise. It is the responsibility of the applicant to describe how the included collaboration will augment the PIs expertise to best address the research question. All applicants for the New Investigator categories must meet the specific eligibility criteria described in Section II.C, Eligibility Information.Preliminary data relevant to DMD that supports the feasibility of the research hypotheses and research approaches are required. Preliminary data may include unpublished results from the laboratory of the PI, research team or collaborators named on the application.Key elements of this award are as follows:Innovation: Research deemed innovative may introduce a new paradigm, challenge current paradigms, look at existing problems from new perspectives, or exhibit other uniquely creative qualities.Impact: Research that has high potential impact may lead to major advancements and significantly accelerate progress toward improving outcomes for individuals with DMD.It is the responsibility of the PI to clearly and explicitly articulate the projects innovation and its potential impact on DMD. The projects impact to both DMD research and to individuals with DMD should be articulated, even if clinical impact is not an immediate outcome. Applications that demonstrate exceptional scientific merit but lack innovation and high potential impact do not meet the intent of the IDA.Clinical trials are not allowed under this funding opportunity.A clinical trial is defined in 45 CFR 46.102 as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes.Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.For the purposes of this funding opportunity, research that meets the definition of a clinical trial is distinct from clinical research. Clinical research encompasses research with human data, human specimens, and/or interaction with human subjects. Clinical research is observational in nature and includes:(1) Research conducted with human subjects and/or material of human origin such as data, specimens, and cognitive phenomena for which an investigator (or co-investigator) does not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention. Research meeting this definition may include but is not limited to: (a) mechanisms of human disease, (b) diagnostic or detection studies (e.g., biomarker or imaging), (c) health disparity studies, and (d) development of new technologies.(2) Epidemiologic and behavioral studies that do not seek to assess the safety, effectiveness, and/or efficacy outcomes of an intervention.(3) Outcomes research and health services research that do not fit under the definition of clinical trial.Excluded from the definition of clinical research are in vitro studies that utilize human data or specimens that cannot be linked to a living individual and meet the requirements for exemption under 46.104(d)(4) of the Common Rule.

This funding opportunity provides financial support to designated regional consortia that include educational institutions, government entities, and industry partners to advance critical technologies and foster economic growth in their areas.