Grants for For profit organizations other than small businesses - Federal

The FY24 PRMRP Clinical Trial Award supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of a disease or condition addressed in one of the congressionally directed FY24 PRMRP Topic Areas and FY24 PRMRP Strategic Goals. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials (e.g., pilot, first in human, phase 0) to demonstrate the feasibility or inform the design of more advanced trials through large-scale phase 1 to phase 3 trials to determine efficacy in relevant patient populations.Applications from investigators within the military Services and applications involving multidisciplinary collaborations among academia, industry, the military Services, the U.S. Department of Veterans Affairs (VA), and other federal government agencies are highly encouraged. These relationships can leverage knowledge, infrastructure, and access to unique clinical populations that the collaborators bring to the research effort, ultimately advancing research that is of significance to Service Members, Veterans, and their Families. If the proposed research relies on access to unique resources or databases, the application must describe the access at the time of submission and include a plan for maintaining access as needed throughout the proposed research.CDMRP encourages research on health areas and conditions that affect women uniquely, disproportionately, or differently from men, including studies analyzing sex as a biological variable. Such research should relate anticipated project findings to improvements in women's health outcomes and/or advancing knowledge for women's health.Funding from this award mechanism must support a clinical trial. A clinical trial is defined in the Code of Federal Regulations, Title 45, Part 46.102 (45 CFR 46.102) as a research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include a placebo or another control) to evaluate the effects of the interventions on biomedical or behavioral health-related outcomes. Studies that do not seek to measure safety, effectiveness, and/or efficacy outcome(s) of an intervention are not considered clinical trials.

This funding opportunity is designed for researchers and teams focused on improving our understanding of snow accumulation and ice flow dynamics in glaciers across the Northern Hemisphere, with an emphasis on airborne and ground-based observations, modeling, and data synthesis.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for projects that support civil society efforts to provide effective civic oversight of the Government of Ukraines (GOU) armed forces, security services,1 and the law enforcement.

This funding opportunity provides financial support for a wide range of physics research projects at U.S. institutions, including universities and nonprofit organizations, to advance knowledge in various subfields of physics.

This funding opportunity is designed to support research institutions and organizations in developing innovative energetic materials and methods to enhance the Army's capabilities in weapon systems and multi-domain operations.

This funding opportunity provides financial support to organizations working to help Vietnam strengthen its legal and regulatory framework for controlling the trade of sensitive technologies and goods related to weapons of mass destruction and advanced conventional weapons.

This funding opportunity provides financial support for a variety of organizations to advance genomic research in pediatric cancers and congenital anomalies, fostering collaboration and innovation in understanding and treating these conditions.

This funding opportunity is designed for researchers developing innovative modeling techniques to improve the wafer bonding processes of thin-film crystals for advanced sensing and communication technologies, with a focus on national security applications.

This funding opportunity supports collaborative research projects aimed at understanding and improving the treatment of chronic pain in infants, children, and adolescents, particularly those with disabilities or from underserved communities.

TOPIC 1: Equal Rights for Marginalized Communities Background: Projects under this funding opportunity should support the efforts of empowering marginalized communities, which include groups that have been traditionally discriminated against because of their identity (race, nationality, gender and gender identity, religious affiliation, disability and socioeconomic status, marital status, and ethnicity) or are particularly vulnerable to marginalization. Competitive projects will clearly identify the challenges facing a marginalized group and sustainable efforts to help advocate for, secure, or exercise their rights. Project Goal: Empower marginalized and vulnerable communities to exercise their human rights by increasing the capacity of civil society and independent media organizations to implement prevention, education, and response efforts in combatting GBV and DV. Project Audience(s): The primary target audience for these projects should be men and women from religiously or socially conservative communities; youth and emerging leaders (14-35 years old); spouses or families of labor migrants; families, government bodies; civil society or advocacy groups; and/or independent media. Projects that support other well-defined marginalized groups and/or with a nexus to family members of radicalized individuals will also be considered. Project Objectives: Each project should achieve one or more of the following objectives: 1. Increase the ability of civil society organizations and advocacy groups to implement and advocate for initiatives combatting GBV and DV through capacity building training. Training topics may include but are not limited to advocacy campaign planning, digital communication tools, messaging best practices, and media engagement strategies. 2. Raise awareness among the Tajik general public of the prevalence, impacts, and consequences of GBV and DV, or discrimination of other marginalized communities, within Tajik society in culturally sensitive and appropriate ways. 3. Facilitate collaboration between civil society organizations, independent media firms and the government bodies to identify and address gaps in existing laws and policies related to GBV/DV prevention or other forms of discrimination through policy dialogues and roundtable discussions. Examples of activities include but are not limited to: Enlisting men as allies in an information campaign to dismantle harmful, violent behavior, and raise awareness among vulnerable women about laws concerning early marriage, domestic abuse, harassment, divorce, alimony, and other civil rights related to women in the family. Conducting educational/outreach/raising awareness activities on the topics related to DV, human trafficking, gender equality, laws related to early marriage, harassment, divorce, and other human rights violation. TOPIC 2: Enabling Environment for Media and the Free Flow of Information Background Independent journalists in Tajikistan face certain career difficulties. These include incomplete or outdated training, lack of prospects outside of state-sponsored media sources, andfor early career journalistslack of experience in telling a story or creating informative, accurate, reliable content. As circulation and revenues from traditional media continue to fall, audiences and journalists increasingly turn to social media for information and profit, but few know how to effectively produce content for this medium that can compete with misinformation, propaganda, and extremist content. Those who do have a better understanding of the techniques and craft of digital production can find themselves chasing audiences with populist topics that may lack journalistic content or integrity. Additionally, many who want to pursue a career in journalism are unable to support themselves and their families financially or are not able to express themselves freely. Project Goal: To contribute to press freedom, the dissemination of accurate information, and the safeguarding journalists including citizen journalist rights by increasing the capacity of journalists and media professionals to produce quality and accurate content that counters misinformation, disinformation, and propaganda. Project Audience(s): Early to mid-career professional journalists, bloggers, social media influencers, and media experts in Tajikistan. Projects to promote and defend media independence and freedom of expression could include media organizations, advocacy groups, managers/editors of media outlets and other influential voices. Project Objectives: Each project should achieve one or more of the following objectives: 1. Strengthen the ability of media associations and organizations to adopt measures that protect their employees and affiliated media professionals from censorship or cyber threats such as hacking, phishing attempts, and website defacement. 2. Equip media associations and organizations with the ability to develop and implement sustainable funding models or revenue strategies that ensure their survival and long-term viability. 3. Improve the reporting of journalists, citizen journalists, bloggers, social media influencers, and other information professionals with regards to ethical reporting practices, investigative journalism, and the use of data analysis tools. 4. Increase media professionals knowledge and awareness about the prevalence and common tactics used in the spread of misinformation, including but not limited to the widespread use of headlines and manipulated content. Examples of activities include but are not limited to: Inviting U.S. or other subject matter experts to train Tajik media professionals and/or advocacy organizations or offer peer to peer mentoring programs. Training Tajik journalists, editors, and media professionals in fact-checking, confirming sources, authenticating images, and identifying bots and AI-produced media. Offering training for bloggers, social media influencers, or amateur citizen journalists with a U.S. expert or other subject matter expert in creating documentary stories for digital media; this could include audio or podcasted stories, short films, or articles that cover issues of local or public interest. Consulting for Tajik media outlets to understand how to monetize their content to become economically sustainable. TOPIC 3: Countering Violent Extremism Background Tajik youth are increasingly radicalized through messages they receive through social media and messenger apps where radical voices are often more active, organized, and better funded than competing voices that advocate tolerance and non-violence. Economically disadvantaged and marginalized youth are most susceptible to radicalization often look to celebrities, athletes, and online imams for guidance over their local community leaders. Project Goal: To provide positive and constructive alternatives to those most at-risk of recruitment into extremist groups by increasing government and/or civil society capacity and engagement in this sphere. Project Audience(s): The primary target audiences are those at-risk of recruitment (Tajik males (ages 15-35) living in rural Tajikistan and Russia, including labor migrants, who have received limited formal education), civil society organizations and government bodies working on countering violent extremism, and respected and popular figures in society who are considered credible voices by those at-risk (religious leaders, teachers, influencers). Project Objectives: Each project should achieve one or more of the following objectives: 1. Raise awareness of target communities and at-risk individuals on the prevalence of violent extremism and recruitment techniques through educational or training initiatives. 2. Equip target communities and individuals at-risk of recruitment into extremist groups with vocational and job search skills for the local job market, focusing on sectors with growth potential. Examples of activities include but are not limited to: Organize summer camps where at-risk youth learn goal setting, soft-skills, and vocational skills/job training, and participate in team building activities, learn about healthy conflict resolution, increase their emotional intelligence, and learn how to tolerate diversity in society. Train at least 10 well-known Tajik athletes (particularly mixed martial artists, boxers, wrestlers, bodybuilders, and football players) or other influential and credible voices to those at-risk (who have a wide following on social media) on the consequences of violent extremism and how to be effective public speakers on the topic. Topic 4: Low Emissions Development Planning for Energy Background: Climate change poses a serious threat to all aspects of Tajikistans society. As the climate warms and natural disasters become more frequent, segments of Tajikistans population that are already vulnerable to economic shocks will become more dependent on the support of civil society and the government to survive. Climate change threatens agriculture and energy sectors through the melting of glaciers and more variable rainfall while also harming the populations health through increased air pollution. Tajikistans reliance on hydropower can serve as a positive example for a world transitioning to renewable sources of energy, but hydropower is also threatened by climate change, as it is highly dependent on glacial melt. Glaciers are receding in Tajikistan at an alarming rate, thus reducing water levels in the reservoirs that power the hydropower plants. Reduced water from glaciers and changing rainfall patterns not only threatens Tajikistans energy security, but also agriculture, and thus has the potential to affect all aspects of society, leading to food insecurity and economic problems. While many parts of Tajikistan have installed micro-hydropower stations, solar power panels are less well-known and utilized. Continued reliance on coal power and polluting industries causes Dushanbe to have the worst levels of air pollution in Central Asia. Project Goal: Support national and sub-national frameworks for low-emissions development by increasing the use of renewable and sustainable energy sources in Tajikistan. Project Audience(s): The primary target audience for these projects should be national and subnational government organizations, civil society, media consumers and outlets, young entrepreneurs, and other well-defined key audiences. Project Objectives: Each project should achieve one or more of the following objectives: 1. Build expertise and capacity in government, private sector, and civil society organizations to analyze emissions sources, set emission reduction targets, and develop mitigation plans through the use of renewable and sustainable energy sources in Tajikistan. 2. Increase collaboration between local, state, and civil society actors/stakeholders to develop practical solutions to combat climate change, advocate for environmental protection legislation, and/or help Tajikistan meet its Global Methane Pledge. Examples of activities include but are not limited to: Conduct workshops, trainings, and/or exchanges to reach the project objectives. This could include hackathons or pitch competitions for young entrepreneurs or those working in related fields (such as data analytics, tech, etc.). Awareness Campaigns promote awareness of emissions and air quality through social and traditional media, produce short video clips for social media and/or TV about environmental issues. Install air quality monitors, test water quality, or improve local capability to conduct data collection, analysis, and reporting on emissions. Organize camps and ongoing actions that teach participants about the environment, promote reforestation initiatives, and/or increase appreciation for nature, including the need for low-emissions development practices.

This funding opportunity supports U.S. researchers and institutions in contributing to the study of exoplanet atmospheres as part of an international mission led by the European Space Agency.

To implement a project aimed at advancing U.S. foreign policy and national security priorities by supporting initiatives that is more reflective of and responsive to the needs and perspectives of partner states to ensure strategic trade control systems meet international standards and by engaging on bilateral, regional and multilateral levels with foreign governments to aid in the establishment of independent capabilities to regulate transfers of weapons of mass destruction, WMD-related items, conventional arms, and related dual-use items, and to detect, interdict, investigate, and prosecute illicit transfers of such items.

This funding opportunity supports U.S. institutions conducting innovative research and investigations in Earth and space sciences, including planetary science, astrophysics, and heliophysics.

This funding opportunity provides financial support to organizations that help family treatment courts improve services for parents facing substance use and mental health challenges in child welfare cases.

This funding opportunity supports projects that empower young Rwandans through education, cultural exchange, and economic development, focusing on areas like STEM, media literacy, and sports diplomacy.

The purpose of this Notice of Funding Opportunity (NOFO) is to support proof-of-concept feasibility trials guided by the NIH Music-based Interventions (MBI) Toolkit for research on brain disorders of aging. These early phase clinical trials will generate evidence supporting the validity of the NIH MBI Toolkits guiding principles as well as the necessary pilot data to design a subsequent clinical efficacy or effectiveness study (or pragmatic clinical trial) using music-based interventions in the context of brain disorders of aging, including but not limited to Alzheimers disease and Alzheimers disease-related dementias, Parkinsons disease, and stroke. The data collected should address gaps in scientific knowledge in order to facilitate development of a competitive large-scale clinical trial.

This funding opportunity provides financial support to organizations that aim to strengthen the capacity and collaboration of State Offices of Rural Health and improve healthcare services in rural communities across the United States.

This grant provides funding to various organizations, including state and local educational agencies, to improve data collection and reporting for special education under the Individuals with Disabilities Education Act (IDEA).

This grant provides funding for organizations to develop projects that promote internet freedom, protect human rights online, and combat censorship and digital security threats.

The Department of States Office of the Nonproliferation and Disarmament Fund (ISN/NDF) is pleased to announce an open competition for assistance awards through this Notice of Funding Opportunity (NOFO). ISN/NDF invites non-profit/non-governmental organizations, international organizations, educational institutions, US federal agencies and institutions, and for-profit organizations to submit proposals for projects that will advance the mission of NDFs biological threat reduction special project. Proposals may not exceed the total availability of funds under this NOFO. ISN/NDF will only consider proposals that fully address all NDFs lines of effort, which are further described in Section II, in their entirety.