Grants for Native American tribal organizations - Federal

The Appalachian Region Healthcare Support Program provides technical assistance (TA) to help rural healthcare organizations, including critical access hospitals (CAHs), small rural hospitals, rural health clinics, tribal healthcare facilities, and other healthcare organizations located in the rural counties served by the Appalachian Regional Commission (ARC) with planning and implementing health care service improvements. The goal of this program is to strengthen healthcare delivery in rural areas of the Appalachian Region by improving financial and operational performance as well as the quality of care in rural healthcare organizations. The TA provider funded under this cooperative agreement will work with individual healthcare organizations to meet the following program objectives: Provide objective analysis and assessment of healthcare organizations financial status, market share, quality indicators, locally available human services, and gaps in services so that organizations can make actionable change; Identify clinical areas where expansion of services within a rural healthcare organization would meet local need, keep health care services available locally, and build capacity to improve financial and operational performance as well as quality of care. Support healthcare organizations in implementing best practice recommendations prioritized in TA action plans. For purposes of this notice of funding opportunity, rural healthcare organization is a health care organization located in a rural area in the Appalachian Region. A healthcare organization includes critical access hospitals, small rural hospitals, rural health clinics, tribal healthcare facilities, and other healthcare organizations. To determine if a health care organization is located in a rural area, visit https://data.hrsa.gov/tools/rural-health. To determine if a county is in the Appalachian Region, visit https://www.arc.gov/appalachian-counties-served-by-arc.For more details, see Program Requirements and Expectations.

Reissue of RFA-NS-18-019: Understanding the dynamic activity of neural circuits is central to the NIH BRAIN Initiative. The invention, proof-of-concept investigation, and optimization of new technologies through iterative feedback from end users are key components of the BRAIN Initiative. This FOA seeks applications to optimize existing or emerging technologies through iterative testing with end users. The technologies and approaches should have potential to address major challenges associated with recording and modulation (including various modalities for stimulation/activation, inhibition and manipulation) of cells (i.e., neuronal and non-neuronal) and networks to enable transformative understanding of dynamic signaling in the central nervous system (CNS). These technologies and approaches should have previously demonstrated their transformative potential through initial proof-of-concept testing and are now ready for accelerated refinement. In conjunction, the manufacturing techniques should be scalable towards sustainable, broad dissemination and user-friendly incorporation into regular neuroscience research.Proposed technologies should be compatible with experiments in behaving animals, validated under in vivo experimental conditions, and capable of reducing major barriers to conducting neurobiological experiments and making new discoveries about the CNS. Technologies may engage diverse types of signaling beyond neuronal electrical activity such as optical, electrical, magnetic, acoustic or genetic recording/manipulation. Applications that seek to integrate multiple approaches are encouraged. If suitable, applications are expected to integrate appropriate domains of expertise, including biological, chemical and physical sciences, engineering, computational modeling and statistical analysis.

The "Clinical Studies of Orphan Products Addressing Unmet Needs of Rare Diseases (R01) Clinical Trials Required" grant aims to fund clinical trials that test the effectiveness and safety of new treatments for rare diseases, with the goal of increasing the number of approved treatments for these conditions.

This grant provides funding for collaborative research teams to develop and test strategies that address and reduce racial and ethnic disparities in substance use and addiction, prioritizing community-driven issues.

The RFSP supports partnerships that connect public and private resources to plan and develop local or regional food systems. The RFSP focuses on building and strengthening local or regional food economy viability and resilience, and this includes pandemic response and recovery. Applicants will work with their partners to catalyze the development of local or regional food systems. Applicants will coordinate efforts within the partnership to set priorities, connect resources and services, and measure progress towards common goals. Partnerships are authorized to:Determine the size and scope of the local or regional food system in which the projects goals, outreach objectives, and eligible activities are to be carried out,Coordinate with AMS to receive technical assistance, andConduct outreach and education for potential participation in the partnership agreement and eligible activities.Partnerships must bring a variety of financial and technical capabilities, demonstrate experience or readiness to work effectively and collaboratively with public and private entities across sectors, and present innovative, sustainable, and measurable approaches to achieving the projects goals. RFSP grant recipients may apply for other LAMP programs on behalf of producers or eligible entities that desire to participate in eligible activities under the partnership agreement.

This grant provides funding for innovative researchers from various scientific fields to develop groundbreaking technologies for recording and manipulating neural activity in the nervous system.

The purpose of this funding opportunity is to support projects which enhance the quality, effectiveness and proven outcomes of nutrition services programs within the aging services network. The Older Americans Act (OAA) provides funding to States and Tribal Organizations to support a broad array of services that enable older adults to remain in their homes and communities and assist family and informal caregivers to care for their loved ones for as long as possible. More information is located here: https://acl.gov/programs/health-wellness/nutrition-services. Through this program, funds will be used to foster the development, testing and replication of innovative service delivery models, policies and partnerships that improve collaboration and coordination between OAA nutrition programs and multi-purpose senior centers. Projects proposed under this grant program must have the potential for broad implementation throughout the aging services network.

Grant Title: Towards a Better Understanding of the Neurological Effects of Infection-Associated Chronic Illnesses (R01 - Clinical Trial Optional) aims to support research on the neurological and mental health impacts of chronic illnesses triggered by infections, such as post-COVID conditions and myalgic encephalomyelitis, focusing on their underlying mechanisms and potential treatments.

As people harmed by domestic violence, dating violence, sexual assault, and stalking seek expanded options to address the harm they have experienced, communities have continued to strengthen and improve their responses, approaches, and services. One such approach is restorative practices. Restorative practices incorporate an understanding of trauma and are intended to repair and address the harm experienced while providing meaningful accountability for the harm-doer. An effective restorative practices program is completely voluntary for the person harmed, promotes their autonomy, and prioritizes their safety, while promoting meaningful justice, accountability, and community safety. The Violence Against Women Act Reauthorization Act of 2022, 34 U.S.C. 12514, authorizes funding to eligible entities to develop and implement a program, or to assess best practices for: 1) restorative practices to prevent or address domestic violence, dating violence, sexual assault, or stalking; 2) training by eligible entities, or for eligible entities, courts or prosecutors, on restorative practices and program implementation; and 3) evaluations of a restorative practice, as defined within the statute. Accordingly, OVW is launching the Restorative Practices Pilot Program in three (3) phases: 1) Training and Technical Assistance; 2) Evaluation; and 3) Pilot Sites. Phase 1: Training and Technical Assistance OVW issued the FY 2023 Restorative Practices Technical Assistance Pilot Program Call for Concept Papers in March 2023 to identify organizations with the requisite experience and capacity to provide Training and Technical Assistance (TTA) to recipients, subrecipients, and potential recipients and subrecipients of this program. Following an intensive review of responses to the Call for Concept Papers, OVW invited five entities to submit full applications. OVW issued awards to three of those applicants in March 2024 for five-year TTA projects that will run from April 2024 through March 2029 and will involve a planning phase. In addition to providing TTA to the pilot sites, the TTA providers will participate in evaluation efforts funded through the FY 2024 Restorative Practices Pilot Program Evaluation Solicitation. The TTA providers are funded under a separate funding announcement. This solicitation is exclusively intended to fund pilot sites of the Restorative Practices Pilot Sites Program. Phase 2: Evaluation In March 2024, OVW released the Restorative Practices Pilot Program Evaluation Solicitation to invite applications to conduct research and evaluation on restorative practices in collaboration with TTA providers and pilot sites. While pilot sites funded through this Restorative Practices Pilot Sites Program Solicitation will be required to provide funding for and designate an on-site Evaluation Liaison to work with evaluator(s) and participate in the community-tailored evaluation, the comprehensive evaluation will be funded under that separate funding announcement. This solicitation is exclusively intended to fund pilot sites of the Restorative Practices Pilot Sites Program. Phase 3: Pilot Sites (this solicitation) This Restorative Practices Pilot Sites Program is a 60-month funding opportunity seeking to support, strengthen, enhance, and expand existing restorative practice programs that prevent or address domestic violence, dating violence, sexual assault, or stalking, in accordance with the restorative practices definition at 34 U.S.C. 12514(a)(3), and build evidence for victim-centered, trauma-informed, and culturally responsive restorative practices addressing these harms. OVW will award cooperative agreements to eligible entities that form a partnership of two or more entities that have (1) a demonstrated history of comprehensive training and experience in working with victims of domestic violence, dating violence, sexual assault, or stalking; and (2) demonstrated experience in implementing restorative practices. OVW is interested in supporting communities to enhance or expand current efforts, including an evaluation of the intersection of domestic violence, dating violence, sexual assault, stalking and restorative practices. In addition, OVW seeks to fund a range of pilot sites, including sites in various geographic locations with different demographic characteristics; culturally specific, and/or underserved populations; and different VAWA subject areas to be addressed (i.e., domestic violence, dating violence, sexual assault, and/or stalking). OVW is interested in supporting projects that implement a diverse range of restorative practices, including projects that may have a connection to the criminal justice system, as long as the program is not housed within or administered by a court, prosecutors office, law enforcement agency, or any other component of the civil or criminal justice system. Recipients under this program will receive TTA for the duration of their awards that is tailored to the recipients distinct approach to restorative practices in domestic violence, dating violence, sexual assault, and stalking cases. Recipients will be required to collaborate with the evaluator(s) to help develop an understanding of establishing, implementing, and using restorative practices to redress the harm caused by domestic violence, dating violence, sexual assault, and stalking. The terms used throughout this solicitation may vary from people harmed, people who caused harm, harm-doers, victim, survivor, and offender, which reflects terminology used by practitioners and the statutory language that authorizes this program, 34 U.S.C. 12514.

This funding opportunity supports research into the biology and mechanisms of bladder cancer, encouraging multidisciplinary teams to explore both normal bladder functions and cancer processes using clinical specimens.

This funding opportunity provides financial support for conservation projects aimed at protecting candidate and at-risk species in the U.S., targeting a wide range of eligible applicants including governments, non-profits, and individuals.

The purpose of the NIH Mentored Research Scientist Development Award (K01) is to provide support and protected time (three to five years) for an intensive, supervised career development experience in the biomedical, behavioral, or clinical sciences leading to research independence. Although all of the participating NIH Institutes and Centers (ICs) use this support mechanism to support career development experiences that lead to research independence, some ICs use the K01 award for individuals who propose to train in a new field or for individuals who have had a hiatus in their research career because of illness or pressing family circumstances. Other ICs offer separate K01 FOAs intended to increase research workforce diversity.

This funding opportunity supports innovative, early-stage research involving human participants to advance biomedical and clinical science, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

This grant provides funding to support postdoctoral researchers from diverse backgrounds as they transition into independent faculty positions in biomedical research.

The purpose of this research is to systematically evaluate the diastereomeric composition of LEQVIO (Inclisiran), an FDA-approved, N-acetyl galactosamine (GalNAc)-conjugated siRNA drug, and to understand the biological/pharmacological activity of each diastereomer in LEQVIO through stereo chemically controlled synthesis and biological activity assessment using in vitro and animal models. The proposed studies will focus on 1) synthesis of each diastereomer of LEQVIO (Inclisiran) in stereo chemically pure form; 2) assessment of the biological activity of each stereo chemically pure diastereomer in inhibiting PCSK9 activity using in vitro assays and in a transgenic mouse model; 3) development of analytical methods to identify and characterize the stereochemical structure of each diastereomer in LEQVIO; and 4) assessment of the individual contribution of each diastereomer to the overall pharmacological activity of LEQVIO. Tools developed in this research can also be applied to other similar GalNAc-conjugated siRNAs specifically, and other siRNAs in general. Knowledge gained from this research will also contribute to the sameness evaluation of generic siRNAs, and to the quality control of oligonucleotide drugs.

This funding opportunity provides financial support to organizations that develop and expand telehealth programs, enabling pediatric primary care providers to better address the mental health needs of children and adolescents, particularly in underserved areas.

This grant provides funding to civil society organizations in Uganda to strengthen their capacity and coordination in delivering comprehensive HIV prevention and treatment services to key and priority populations at high risk of HIV infection.

The purpose of this Funding Opportunity Announcement (FOA) is to 1) invite applications that propose to develop and implement early to late stage clinical trials of promising pharmacological and non-pharmacological interventions for cognitive and neuropsychiatric changes associated with age-related cognitive decline and Alzheimer's disease (AD) and Alzheimer's disease-related Dementias (ADRD) across the spectrum from pre-symptomatic to more severe stages of disease, and 2) stimulate studies to enhance trial design and methods.

This funding opportunity supports U.S. colleges and universities with limited research funding to assess their biomedical research capabilities and develop strategic plans to enhance their research infrastructure and capacity.

This notice is not a mechanism to fund existing NOAA awards. The purpose of this notice is to request applications for special projects and programs associated with NOAA's strategic plan and mission goals, as well as to provide the general public with information and guidelines on how NOAA will select applications and administer discretionary Federal assistance under this Broad Agency Announcement (BAA).This Broad Agency Announcement is a mechanism to encourage research, education and outreach, innovative projects, or sponsorships that are not addressed through NOAA’s competitive discretionary programs. This announcement is not soliciting goods or services for the direct benefit of NOAA. Funding for activities described in this notice is contingent upon the availability of Fiscal Year 2021, Fiscal Year 2022, and Fiscal Year 2023 appropriations. Applicants are hereby given notice that funds have not yet been appropriated for any activities described in this notice. Publication of this announcement does not oblige NOAA to review an application beyond an initial administrative review, or to award any specific project, or to obligate any available funds. As an agency with responsibilities for maintaining and improving the viability of marine and coastal ecosystems, for delivering valuable weather, climate, and water information and services, for understanding the science and consequences of climate change, and for supporting the global commerce and transportation upon which we all depend, NOAA must remain current and responsive in an ever-changing world. We do this in concert with our partners and stakeholders in Federal, state, and local governments and private organizations, applying a systematic approach that links our strategic goals through multi-year plans to the daily activities of our employees. Every year we are committed to re-evaluate our progress and priorities, look for efficiencies, and take advantage of new opportunities to improve our information, products, and services. In furtherance of this objective, NOAA issues this BAA for extramural research, innovative projects, and sponsorships (e.g., conferences, newsletters, etc.) that address one or more of the following four mission goal descriptions contained in the NOAA Strategic Plan: Climate Adaptation and Mitigation Weather-Ready Nation Healthy Oceans Resilient Coastal Communities and Economies