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Grants for Nonprofits - Federal

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2025 AWE Alumnae Regional Summit
$26,000
Department of State - Bureau of Western Hemisphere Affairs
Federal

Application Deadline

Jul 22, 2024

Date Added

Jul 18, 2024

The U.S. Embassy Nassaus Public Diplomacy (PD) section announces an open competition for organizations to submit applications to develop and organize a Regional Alumnae Summit for the Academy for Women Entrepreneurs (AWE) network throughout the Caribbean. The PD section invites proposals from non-profit organizations, civil society organizations, and U.S. government alumni organizations to design and organize a summit to connect small and medium businesses of AWE Alumnae from across the Caribbean during a 2-day Summit in Nassau, The Bahamas in Spring 2025. This Summit will also provide a forum for AWE Alumnae to expand their professional network, share best practices and gain broader market access. In consultation with the U.S. Embassy Public Diplomacy team, the awardee is expected to organize all logistics for the Summit to include, but not limited to several deliverables. Therefore, the proposal should clearly describe how each item below will be addressed: Structure and Overall plan for the event. The estimated Cost for the proposed Venue for the Summit. Equipment (Equipment cannot account for more than 10% of the total project cost.) Marketing plan Proposed 6 Conference Speakers and associated costs (this should include Bahamian, Caribbean and American Entrepreneurs as well as a Keynote Speaker.) Travel Costs for participants from Family Islands. A Business Expo opportunity for participants. Opportunities for participants to scale up their businesses (ex. export, product development and scaling.) Cost Share (not required but looked upon favorably) Public Private Partnerships Pre and Post Surveys for participants (ex. To garner input for topics for summit)

Women & Girl Services
Nonprofits
Fy25 Vietnam Wartime Accounting Initiative Cooperative Agreements
$550,000
U.S. Department of Defense (Washington Headquarters Services)
Federal

Application Deadline

Sep 28, 2025

Date Added

Aug 29, 2025

This grant provides funding to three specific organizations to support efforts in locating and recovering missing persons from the Vietnam War, thereby enhancing U.S.-Vietnam defense cooperation and addressing humanitarian concerns.

International Development
Public and State controlled institutions of higher education
Landscape Characterization and Monitoring in the Chesapeake Bay Watershed
$6,500,000
Environmental Protection Agency
Federal

Application Deadline

Jul 19, 2024

Date Added

May 20, 2024

Authorized by Clean Water Act (CWA) Section 117, 33 USC Section 1267, the Chesapeake Bay Program (CBP) is a unique regional, state, federal, and local partnership that has been directing and conducting the restoration and protection of the Chesapeake Bay. CBP is responsible for supporting the Chesapeake Bay Executive Council (Executive Council) through a number of actions, including the coordination of federal, state, and local efforts to restore and protect living resources and water quality of the Chesapeake Bay and its watershed. The Notice of Funding Opportunity is seeking insightful, expert, and cost-effective applications from eligible applicants to provide the CBPs non-federal partners with updated land use/land cover data, enhanced river corridor data, and landscape metrics and communication products associated with these data to facilitate their application to CBP's outcomes and the CBPs Phase 7 suite of modeling tools. For more information, please see the funding opportunity.

Environment
Nonprofits
DFC Support Program National Community Anti-Drug Coalition Institute (NCI)
$2,500,000
Office of National Drug Control Policy
Federal

Application Deadline

Sep 16, 2024

Date Added

Aug 13, 2024

Adolescence is a critical risk period for substance use initiation and adverse outcomes related to substance use, particularly as drug use has been found to escalate between ages 12 and 19. The goal of substance use prevention efforts is to prevent and/or delay the first use of substances. Research shows that early age of onset is an important predictor for the development of a substance use disorder later in life. Further, research shows that prevention interventions can have positive long-term effects in reducing substance use. Recognizing that preventing or delaying initiation of substance use can confer important health and social benefits, the purpose of the NCI is to serve as the training and technical assistance partner for DFC and non-DFC funded community coalitions across the country by enhancing the capacity of the prevention workforce and others in the prevention community to implement evidence-based interventions.

Health
Nonprofits
Combating Antibiotic-Resistant Bacteria Interdisciplinary Units (CARBIRUs) (P01 Clinical Trial Not Allowed)
$1,500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 26, 2025

Date Added

Nov 5, 2024

This grant provides funding for interdisciplinary research teams to develop innovative strategies for preventing and treating infections caused by antibiotic-resistant bacteria.

Health
State governments
Energy Improvements in Rural or Remote Areas Fiscal Year 2025 Release
$50,000,000
U.S. Department of Energy (Headquarters)
Federal

Application Deadline

Aug 28, 2025

Date Added

Jun 5, 2025

This funding opportunity provides financial support for clean energy projects in rural and remote areas, targeting communities with 10,000 residents or fewer to reduce energy costs and improve access to sustainable energy solutions.

Energy
Native American tribal organizations
Women's Business Center Application Readiness and Procurement Assistance
$150,000
U.S. Small Business Administration
Federal

Application Deadline

Aug 7, 2024

Date Added

Jun 11, 2024

The purpose of this Funding Opportunity Announcement (FOA) is to provide grant funding for organizations to establish Womens Business Centers (WBCs) to assist women entrepreneurs with application readiness for certification in the Women-Owned Small Business (WOSB) and Economically Disadvantaged Women-Owned Small Business (EDWOSB) Programs, procurement assistance, and entrepreneurial development.

Business and Commerce
Nonprofits
DRL FY23 Combatting Transnational Repression Globally
$2,640,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

May 6, 2024

Date Added

Mar 5, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in submitting applications for a global project to 1) dissuade and deter governments from engaging in and/or facilitating transnational repression (TNR) activities and 2) mitigate the impact of TNR activities on individuals and communities. Competitive proposals will incorporate activities in at least three regions as defined by the State Department (Sub-Saharan Africa, East Asia and the Pacific, Europe and Eurasia, Middle East and North Africa, South and Central Asia, and Western Hemisphere).

International Development
Nonprofits
OJJDP FY25 National Mentoring Programs
$30,000,000
U.S. Department of Justice (Office of Juvenile Justice Delinquency Prevention )
Federal

Application Deadline

Nov 3, 2025

Date Added

Sep 19, 2025

This funding opportunity provides financial support to national organizations for delivering mentoring services to at-risk youth, particularly those involved in or affected by the juvenile justice system, across at least 38 states.

Youth
Nonprofits
DRL Strengthening the Rights of Workers in the Care Economy
$1,000,000
DOS-DRL (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

Jul 15, 2024

Date Added

Jun 17, 2024

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in strengthening the rights of workers in the care economy in line with internationally recognized labor standards.

Workforce Development
Nonprofits
Leveling the Field for American Workers in U.S.-Mexico Trade
$10,000,000
U.S. Department of Labor (Bureau of International Labor Affairs)
Federal

Application Deadline

Sep 26, 2025

Date Added

Jul 22, 2025

This grant provides funding to organizations working to improve labor conditions in Mexico's key trade sectors, ensuring fair practices that benefit American workers and businesses.

Employment Labor and Training
Nonprofits
Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2025

Date Added

Oct 8, 2024

This funding opportunity supports research projects that combine imaging techniques and liquid biopsies to improve cancer treatment monitoring and response assessment in clinical settings.

Education
State governments
Strengthening American Infrastructure (SAI)
$9,600,000
National Science Foundation
Federal

Application Deadline

Mar 6, 2026

Date Added

Apr 21, 2025

This funding opportunity supports interdisciplinary research projects that enhance U.S. infrastructure by integrating social, behavioral, and economic sciences with engineering and technology to promote community equity, resilience, and national security.

Infrastructure
Nonprofits
University Capacity Building Program, UCBP
$250,000
U.S. Department of State - U.S. Mission to Georgia
Federal

Application Deadline

Aug 9, 2024

Date Added

Jul 2, 2024

PROGRAM DESCRIPTION The Public Diplomacy Section (PDS) of the U.S. Embassy in Tbilisi, Georgia, is pleased to announce an open competition for a University Capacity Building Program (UCBP). U.S. non-profit, non-governmental organizations and accredited American higher education institutions may submit proposals to manage a 12-to-18-month professional development program for Georgian university administrators, development and grant officers, as well as higher education decision-makers/government officials responsible for higher education management and administration. The proposed University Capacity Building Project, UCBP, will take a comprehensive approach to assist Georgian universities in building a functioning research administration and development infrastructure. UBCP will help higher education institutions (HEIs) build or expand the foundations of research administration and development at their institution and support their diffusion throughout Georgia. Further, the activities will provide participants with best practices on how to leverage and integrate the contributions from universities in this area to promote innovation and collaboration with various stakeholders, ranging from industry to government entities, to improve the economy of Georgia. The activities will be divided into four phases that will include a mixture of online classes/presentations/webinars, a two-week study tour, follow-up online consultations with a grantee and/or selected US host universities aimed at identifying common area/s of interest for development of a joint research proposal/project and a reciprocal visit of US instructors to Georgia. The program phases include: 1. Needs assessment of the capacities of research administration and development offices of UCBP participant universities in Georgia; 2. Increase Georgian HEIs research capacity and deepen US-Georgian university partnership through online mentoring sessions and practical workshops on effective grant writing/ proposal development, strategic communication with donors, alumni engagement, and fundraising); 3. U.S. Study Tour (14 days including travel) including Washington, DC and non-coastal cities for developing joint research initiatives, alumni engagement strategies and effective donor communication plans; and 4. US experts reciprocal visit (10 days including travel) to Georgia aimed at establishing and enhancing the community of US-Georgian researchers and university administrators. PROGRAM OBJECTIVES The UCBP seeks to better leverage and integrate the various missions education, research, and engagement in order to increase the contribution of higher education and public research institutions to innovation and economic growth and develop the commercial and entrepreneurial aspects of Georgian academia by presenting successful American models. University administrators responsible for research, sponsored programs, and external affairs will learn how to enhance the university organizational environment. This can be accomplished by sharing successful and collaborative grant office and faculty department structures and training and supporting university grant teams to improve their grant funding efforts. The proposed study tour will assist university leaders in learning how to optimize best practices and organizational structures to cope with the pressures of external forces like limited funding and increased demand for research in the competitive higher education marketplace. Cooperation with universities in non-coastal cities in the United States is encouraged. The project will: help participants understand the foundational infrastructure necessary for success, including university support offices, effective research development activities, successful grant writing, effective alumni engagement strategies, strategic communication with donors and fundamentals of fundraising. These objectives will be realized through intensive online webinars and practical workshops; a study tour of U.S. universities; and reciprocal visits by experts to Georgia to support the project implementation. Help to institutionalize research development/grant offices in universities to liaise with local private sector entities, through various means, including online platforms. Such linkages would provide platforms for exchange of ideas, imagining of opportunities, and establishing networks; Establish a network of professionals from various universities, government agencies, and professional associations that work together on enhancing the university-private sector-innovation triangle; Help to create a common agenda for regular discussions between academics and entrepreneurs by nurturing entrepreneurial ecosystems at universities. Following topics/activities (the list can be further expanded) may be supported: a. Research Administration in a United States University: Organization and Function b. Identifying Requests from Sponsors (Private vs Government; Domestic vs International, US vs Non-US models) c. Responding to requests for proposals d. Effective grant writing e. Budgeting effectively (direct and indirect costs) f. Administrative support i. Pre-award support ii. Proposal development g. Partnering with other universities on elaboration of joint research proposals/projects h. Developing and executing effective alumni engagement strategies i. Effective strategic communication with donors j. Fundraising principals and fundamentals of successful fundraising campaigns Applicants may propose other activities not specifically mentioned in this solicitation if the activities reinforce the impact of the project. A detailed program timeline for the entire grant period that outlines how components unfold and complement each other must be included in the proposal. The names of proposed Georgian participants must be reviewed and approved in advance of U.S. travel by the Public Diplomacy Section (PDS) of the U.S. Embassy in Tbilisi. PDS anticipates that the majority of Georgian participants will not have working-level competency in English and high-quality (preferably simultaneous) translation will need to be budgeted in the grant, as should airfare, hotel, international travel insurance, the B1/B2 visa fee, and meals and incidental expenses for study tour participants. For monitoring, evaluation, and learning (MEL) purposes, the PDS Grant Officer Representative (GOR) will serve as a facilitator for the study tour. GOR expenses will be covered by the U.S. Embassy. EXPECTED RESULTS The projects aim is to provide a foundation of knowledge and capacity to grow and sustain a modern research administration and development office. This may be occurring the following ways: 1. Provide partner institutions with the understanding of the importance of developing a successful Research Administrative and Development Office. 2. Provide the knowledge base necessary for participants to set up their Research Administrative and Development Office that can become a highly functioning part of their institution. a. Develop understanding of the functions and importance of research administration and development. b. Teach participants how to respond effectively to funding opportunities US and non-US, as well as EU funding sources. c. Teach participants how to identify appropriate funding opportunities. d. Train participants to become a trainer (TOT model) who can effectively pass this knowledge base on to their peers in grant writing and fundraising. 3. Develop greater research capacity for each partner university, collaborate on producing joint research proposals/projects/programs. 4. Allow Georgian and US universities to establish strong international partnerships that could lead to multi-directional programming and collaborative research. 5. Collaborate with US partner universities on elaboration and adoption of an Alumni Engagement Strategy and mutually acceptable action plan. 6. Introduce best working models of Public-Private Partnerships (PPP) and establish institutionalized ties between the universities and business associations, thus contributing to Georgian universities more effective collaboration with potential employers in private sector and government. Participants and Audiences: Audiences for the proposed project would include university research administrators and development officers, higher education administrators, researchers and relevant policy makers.

Education
Public and State controlled institutions of higher education
Supporting lifesaving HIV/AIDS service delivery programs in Haiti under the President's Emergency Plan for AIDS Relief (PEPFAR)
$15,000,000
U.S. Department of Health and Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 17, 2026

Date Added

Oct 2, 2025

This funding opportunity provides financial support for organizations to deliver essential HIV/AIDS services in Haiti, focusing on testing, treatment, and care for affected individuals and communities.

Health
State governments
Emergency Department Substance Use Surveillance System
$150,000
Office of National Drug Control Policy
Federal

Application Deadline

Sep 17, 2024

Date Added

Sep 17, 2024

This project seeks to further refine and geographically expand a methodology for obtaining drug early warning indicators through broader testing of urine samples that were previously collected and tested as part of an existing drug test protocol. This method was initially developed using local criminal justice populations including persons in pre-trial or lock-up, parolees or probationers, and drug court participants. A similar methodology is promising for use in other venues, such as in trauma units and emergency departments, where biological samples are often collected from patients. Before the specimens are discarded, the project will re-test them for an expanded panel of drugs, including xylazine, fentanyl, methamphetamine, and other new psychoactive substances (NPS); to determine what old and new illicit drugs are detected or missed by conventional testing protocols, and how the drug patterns might vary by subpopulation and geography. Bypassing the expense of collecting the original specimens and re-using those that have already been tested with known results yields a relatively inexpensive and timely picture of emerging drugs in a given subpopulation and locality. Hospital and de-identified nationally representative patient electronic health records (EHRs) should be collected and analyzed to put re-tested urine positivity results into a larger regional and national context of drug exposure and consequences. ONDCP is seeking to apply this testing methodology and insight from supplemental EHR investigations to emergency department and other hospital-system populations in locations throughout the United States to reinforce best practice guidelines, testing standardization, and build local and national surveillance capacity.

Health
Public and State controlled institutions of higher education
Catalyze: Product Definition for Small Molecules and Biologics - Preliminary Product/Lead Series Identification (R33 - Clinical Trial Not Allowed)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 21, 2024

Date Added

Jan 24, 2022

This funding opportunity supports early-stage research to develop new therapeutic agents for heart, lung, blood, and sleep disorders, specifically targeting projects that have identified promising small molecules or biologics ready for preclinical testing.

Health
State governments
The Metastasis Research Network (MetNet): MetNet Research Projects (U01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 24, 2024

Date Added

Aug 25, 2022

The Metastasis Research Network (MetNet) Research Projects grant aims to fund research projects that use comprehensive, systems-level approaches to address gaps in metastasis research, particularly focusing on themes like dormancy, early dissemination, and cellular or physical microenvironment interactions, with the goal of enhancing our understanding of metastasis as a whole-body, systems-level issue.

Education
State governments
2025 Regional Ecosystem Research (RER) Program: Understanding Species Habitat Usage and Connectivity in and around Marine Protected Areas
$2,000,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jan 23, 2025

Date Added

Oct 9, 2024

The 2025 Regional Ecosystem Research (RER) Program grant, offered by NOAA's NCCOS, aims to fund research projects that enhance understanding of species' habitat usage and connectivity in Marine Protected Areas, with the goal of improving conservation efforts and management plans, particularly in line with the 30x30 initiative.

Natural Resources
Public and State controlled institutions of higher education
Bureau of Democracy, Human Rights, and Labor Request for Statements of Interest: FY 2024 China Programs
$1,500,000
U.S. Department of State (Bureau of Democracy Human Rights and Labor)
Federal

Application Deadline

Jan 16, 2025

Date Added

Dec 19, 2024

This funding opportunity invites organizations to propose initiatives that address human rights abuses and promote democratic values in China, focusing on freedom of expression, access to information, and labor rights.

International Development
Nonprofits