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Grants for Nonprofits - Federal

Explore 5,497 grant opportunities

Integration of Imaging and Fluid-Based Tumor Monitoring in Cancer Therapy (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 7, 2024

This grant provides funding for researchers to develop and integrate imaging and liquid biopsy techniques to improve cancer treatment monitoring and early detection of treatment resistance.

Education
State governments
Rural Microentrepreneur Program(RMAP)
$500,000
U.S. Department of Agriculture (Rural Business-Cooperative Service )
Federal

Application Deadline

Jun 30, 2026

Date Added

Feb 27, 2026

This program provides financial support and technical assistance to nonprofit organizations, Indian Tribes, and educational institutions to help rural entrepreneurs start and grow their small businesses.

Business and Commerce
Nonprofits
Blueprint Neurotherapeutics Network (BPN): Small Molecule Drug Discovery and Development of Disorders of the Nervous System (UG3/UH3 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 18, 2026

Date Added

Sep 26, 2024

This grant provides funding for researchers to develop small molecule drugs targeting nervous system disorders, with support from NIH resources for drug discovery and clinical testing.

Education
State governments
Opportunities for Collaborative Research at the NIH Clinical Center (U01 Clinical Trial Optional)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 5, 2027

Date Added

Jun 18, 2025

This funding opportunity supports collaborative research projects that bring together NIH scientists and external researchers to advance patient-centered clinical studies using the unique resources of the NIH Clinical Center.

Health
State governments
FY 2026 National Security Language Initiative for Youth (NSLI-Y)
$5,000,000
U.S. Department of State (Bureau Of Educational and Cultural Affairs)
Federal

Application Deadline

May 1, 2026

Date Added

Mar 4, 2026

This grant provides funding for U.S.-based nonprofit organizations and educational institutions to create immersive language learning programs for American high school students, enhancing their proficiency in critical foreign languages through overseas and virtual experiences.

Education
Nonprofits
Communications, Circuits, and Sensing-Systems
$2,470,673
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant supports innovative research in communication, circuit, and sensing technologies to develop advanced systems that address societal challenges in areas like healthcare, environmental monitoring, and intelligent transportation.

Science and Technology
For profit organizations other than small businesses
EDU Core Research
$2,500,000
National Science Foundation
Federal

Application Deadline

Oct 1, 2026

Date Added

May 23, 2025

This program provides funding for researchers to explore and improve STEM education, focusing on learning environments, broadening participation, and workforce development across various age groups and settings.

Education
Public and State controlled institutions of higher education
NIDCR Dual Degree Dentist Scientist Pathway to Independence Award (K99/R00 Clinical Trial Not Allowed)
$249,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 12, 2028

Date Added

Jun 18, 2025

This funding opportunity supports dentist scientists with both clinical dental and research doctoral degrees, helping them transition from mentored postdoctoral training to independent research careers in dental, oral, and craniofacial health.

Health
Individuals
NDEP STEM Open NFO
Contact for amount
U.S. Department of Defense (Washington Headquarters Services)
Federal

Application Deadline

Feb 8, 2028

Date Added

May 21, 2025

This funding opportunity supports innovative STEM education and workforce development initiatives aimed at enhancing national security by cultivating a skilled technical workforce, particularly for underrepresented groups and military-connected individuals.

Education
Nonprofits
Limited Competition for the Continuation of the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) Data Analysis Resource (U24 Clinical Trials Optional)
$600,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 1, 2026

Date Added

May 23, 2025

This funding opportunity supports research institutions and organizations in studying the long-term effects of adolescent alcohol use on brain development and health outcomes, aiming to improve prevention strategies for alcohol use disorders.

Health
State governments
Infrastructure Innovation for Biological Research
$800,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 23, 2025

This program provides funding for the development of innovative research tools and methods that enhance biological research, targeting universities, community colleges, and nonprofit organizations involved in biological sciences.

Science and Technology
Public and State controlled institutions of higher education
FY 2026 English Language Fellow, Specialist, and Virtual Educator Program
$14,000,000
U.S. Department of State (Bureau Of Educational and Cultural Affairs)
Federal

Application Deadline

Apr 24, 2026

Date Added

Feb 16, 2026

This grant provides funding to U.S.-based nonprofit organizations and educational institutions to deploy English language professionals worldwide, enhancing English instruction and promoting U.S. educational values and diplomacy.

Education
Nonprofits
Prize for Resilient Grid Innovation
$225,000
U.S. Department of Energy (DOE)
Federal

Application Deadline

Apr 9, 2026

Date Added

Mar 10, 2025

This funding opportunity provides $2.5 million to support partnerships among utilities, energy sector partners, and tech developers to improve data management and resilience in the electric grid.

Energy
State governments
Modular R01s in Cancer Control and Population Sciences (R01 Clinical Trial Optional)
$250,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2026

Date Added

Nov 8, 2024

This funding opportunity supports innovative research aimed at improving cancer prevention, control, and survivorship through interdisciplinary approaches in behavioral science, epidemiology, and data analytics, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

Education
State governments
NCI Pathway to Independence Award for Early-Stage Postdoctoral Researchers (K99/R00 - Independent Clinical Trial Not Allowed)
$249,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Nov 8, 2023

This grant provides financial support to early-stage postdoctoral researchers in cancer-related fields, helping them transition from mentored training to independent research careers.

Health
State governments
Automated Processes For Knowledge Discovery And Information Retrieval
$35,000,000
U.S. Department of Defense (Department of the Air Force)
Federal

Application Deadline

Sep 9, 2029

Date Added

Sep 22, 2025

This funding opportunity is designed to support U.S. entities, including universities, nonprofits, and businesses, in developing innovative technologies for analyzing and utilizing multi-source data to improve military decision-making and enhance national defense capabilities.

Science and Technology
Public and State controlled institutions of higher education
Cognitive Neuroscience
$225,000
National Science Foundation
Federal

Application Deadline

Aug 17, 2026

Date Added

Feb 19, 2025

This program provides funding for researchers investigating the neural mechanisms of human cognition, encouraging innovative studies that combine physiological data with behavioral analysis to enhance our understanding of processes like memory, decision-making, and emotion.

Science and Technology
Public and State controlled institutions of higher education
Stephen I. Katz Early Stage Investigator Research Project Grant (R01 Basic Experimental Studies with Human Required)
Contact for amount
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 25, 2028

Date Added

May 13, 2025

This grant provides funding for early stage researchers to explore innovative, high-risk projects involving human participants without needing preliminary data.

Education
State governments
EPSCoR Research Infrastructure Improvement Program: EPSCoR Research Incubators for STEM Excellence
$8,000,000
National Science Foundation
Federal

Application Deadline

Aug 11, 2026

Date Added

May 22, 2025

This grant provides funding to higher education institutions and non-profit organizations in eligible jurisdictions to develop sustainable research incubators that enhance STEM research capacity and collaboration.

Science and Technology
Public and State controlled institutions of higher education
EPSCoR Research Infrastructure Improvement Program: Focused EPSCoR Collaborations Program (FEC)
$6,000,000
National Science Foundation
Federal

Application Deadline

Jan 26, 2027

Date Added

May 22, 2025

This grant provides funding for collaborative research projects between institutions in eligible jurisdictions to strengthen STEM research infrastructure and promote workforce development.

Science and Technology
Public and State controlled institutions of higher education