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Federal for Small businesses Grants

Explore 142 grant opportunities

SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1 Clinical Trial Not Allowed)
Contact for amount
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 5, 2026206 days left

Date Added

Jun 11, 2025

This funding opportunity provides financial support to small businesses developing innovative health-related technologies, helping them advance their projects toward commercialization through technical assistance and late-stage development activities.

Health
Small businesses
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (UT1/UT2) Clinical Trial Not Allowed
$1,972,828
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 6, 2025115 days left

Date Added

Jun 7, 2025

This funding opportunity supports U.S.-based small businesses in developing and manufacturing therapeutic extracellular vesicles for regenerative medicine applications, focusing on tissue and organ repair.

Health
Small businesses
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)
$1,972,828
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 6, 2025115 days left

Date Added

Jun 7, 2025

This funding opportunity supports small U.S.-based businesses in developing and scaling innovative therapies using extracellular vesicles for regenerative medicine applications, such as tissue and organ repair.

Health
Small businesses
NSF Small Business Innovation Research / Small Business Technology Transfer Phase II Programs
$12,000,000
National Science Foundation (U.S. National Science Foundation)
Federal
Closing Soon

Application Deadline

Jul 2, 202519 days left

Date Added

Jun 2, 2025

This grant provides non-dilutive funding to small businesses and startups for the development of innovative technologies that can transition from research to market, with a focus on creating societal and economic impact.

Science and Technology
Small businesses
NSF Small Business Innovation Research / Small Business Technology Transfer Fast-Track Pilot Programs
$1,555,000
National Science Foundation (U.S. National Science Foundation)
Federal
Closing Soon

Application Deadline

Jul 2, 202519 days left

Date Added

Jun 2, 2025

This grant provides funding to small businesses with prior NSF support to develop and commercialize innovative technologies that address significant societal challenges.

Science and Technology
Small businesses
NSF Small Business Innovation Research / Small Business Technology Transfer Phase I Programs
$305,000
National Science Foundation (U.S. National Science Foundation)
Federal
Closing Soon

Application Deadline

Jul 2, 202519 days left

Date Added

Jun 2, 2025

This grant provides funding to U.S.-based small businesses for innovative research and development projects that have the potential for significant societal and economic impact.

Science and Technology
Small businesses
NIEHS Worker Training Programs SBIR E-Learning for HAZMAT and Emergency Response (R43/R44 Clinical Trial Not Allowed)
$688,000
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 20, 2025160 days left

Date Added

May 22, 2025

This funding opportunity provides financial support for small businesses to develop innovative e-learning training products that enhance the safety and health training of workers dealing with hazardous materials and emergency response situations.

Health
Small businesses
Georgia FAST Grant
$2,450
U.S. Small Business Administration (SBA)
Federal
Rolling

Application Deadline

Not specified

Date Added

May 2, 2025

This program provides funding to Georgia-based small businesses to help them improve their chances of securing federal innovation grants for technology development.

Business and Commerce
Small businesses
FY 2025 NIST Small Business Innovation Research Program Phase II
$400,000
US Department of Commerce (National Institute of Standards and Technology)
Federal
Closing Soon

Application Deadline

Jun 14, 20251 days left

Date Added

Apr 17, 2025

This funding opportunity provides financial support to small businesses that previously received Phase I SBIR grants from NIST, enabling them to further develop their innovative projects into commercially viable products or services.

Science and Technology
Small businesses
Promoting Registration of Inverters and Modules with Ecolabel Prize
$400,000
Solar Energy Technologies Office
Federal

Application Deadline

Not specified

Date Added

Apr 7, 2025

This grant provides financial incentives to U.S.-based manufacturers of solar photovoltaic modules and inverters to achieve environmental certification and promote sustainable energy products.

Energy
Small businesses
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1, Clinical Trial Not Allowed)
$2,000,000
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 5, 202584 days left

Date Added

Apr 4, 2025

This funding opportunity provides financial support to U.S.-based small businesses that have previously received NIH Phase II or Phase IIB awards, helping them advance their research projects toward commercialization through technical assistance and late-stage development activities.

Education
Small businesses
SBIR/STTR Commercialization Readiness Pilot (CRP) Program Technical Assistance and Late Stage Development (SB1 Clinical Trial Required)
$1,750,000
US Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Sep 5, 202584 days left

Date Added

Apr 4, 2025

This funding opportunity provides financial support to small businesses in the U.S. that are developing innovative health-related products and need assistance with late-stage research, clinical trials, and commercialization efforts after receiving prior NIH funding.

Health
Small businesses
FY 2025 Notice of Funding Opportunity for Small Shipyard Grants
$1,000,000
US Department of Transportation (Maritime Administration)
Federal

Application Deadline

May 15, 2025

Date Added

Apr 2, 2025

This program provides funding to small shipyards in the U.S. for capital improvements and workforce training to enhance their operational efficiency and competitiveness in shipbuilding and repair.

Transportation
Small businesses
Small Business Innovation Research FY2025 Phase II
$690,000
US Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Mar 31, 2025

Date Added

Mar 19, 2025

This funding opportunity provides financial support to small businesses that have previously received a Phase I grant to further develop their innovative research and commercialization plans in areas aligned with NOAA's mission.

Business and Commerce
Small businesses
Disruptioneering Program
Contact for amount
Defense Advanced Research Projects Agency (DARPA
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 18, 2025

This funding opportunity is designed for researchers and organizations to explore and develop high-risk, high-reward technologies that can lead to innovative prototypes for national defense applications.

Science and Technology
Small businesses
Defense Sciences Office (DSO) Office-wide BAA
Contact for amount
Defense Advanced Research Projects Agency (DARPA
Federal
Rolling

Application Deadline

Sep 5, 202584 days left

Date Added

Mar 18, 2025

This funding opportunity seeks innovative research proposals from various entities, including businesses and universities, to develop groundbreaking technologies for national security, focusing on areas like novel materials, quantum computing, and artificial intelligence.

Science and Technology
Small businesses
Biological Technologies
Contact for amount
Department Of Defense's Defense Advanced Research Projects Agency
Federal
Rolling

Application Deadline

Sep 10, 202589 days left

Date Added

Mar 18, 2025

This funding opportunity invites U.S. and non-U.S. researchers, including academic institutions and businesses, to develop innovative biotechnological solutions that enhance national security through advancements in areas like medical care, materials, and biosecurity.

Science and Technology
Small businesses
DOE Industrial Training & Assessment Centers Implementation Grants
$300,000
U.S. Department of Energy
Federal
Rolling

Application Deadline

Not specified

Date Added

Mar 10, 2025

This funding opportunity provides financial support to domestic manufacturers and water treatment facilities to improve energy efficiency, boost productivity, and create high-quality jobs while adhering to specific eligibility criteria.

Business and Commerce
Small businesses
Unmanned Robotic Rafting Bays for Military Use
$250,000
U.S. Department of Defense (DoD)
Federal
Rolling

Application Deadline

Not specified

Date Added

Feb 27, 2025

This funding opportunity is designed for small businesses and innovators to develop autonomous robotic systems for military river crossings, enhancing safety and efficiency in contested environments.

Science and Technology
Small businesses
Generative AI-Enabled Tactical Network
$250,000
U.S. Army SBIR Program
Federal
Closing Soon

Application Deadline

Jul 9, 202526 days left

Date Added

Feb 27, 2025

This funding opportunity is designed for small businesses to develop a Generative AI-based software system that creates realistic tactical data for military command and control operations, enhancing decision-making in challenging network environments.

Science and Technology
Small businesses