Grants for Small businesses - Federal
Explore 1,545 grant opportunities
Application Deadline
May 5, 2025
Date Added
Aug 2, 2024
This funding opportunity provides financial support to community coalitions focused on preventing and reducing youth substance use, helping them implement effective strategies and strengthen local partnerships.
Application Deadline
Not specified
Date Added
Mar 18, 2025
This funding opportunity is designed to support innovative prototype projects in military and civil engineering, targeting nontraditional defense contractors, traditional defense contractors, and nonprofit research institutions.
Application Deadline
Feb 5, 2026
Date Added
Jan 14, 2026
This funding opportunity provides financial support to law enforcement agencies across the U.S. to enhance officer safety, wellness, and resilience through comprehensive training and resources.
Application Deadline
Feb 13, 2025
Date Added
Jan 15, 2025
This grant provides funding to small businesses in the U.S. to develop innovative technologies that address critical national needs, particularly in health and technology, while promoting collaboration with research institutions.
Application Deadline
Mar 5, 2025
Date Added
Jul 19, 2024
This grant provides funding to local organizations in Eswatini to improve and integrate HIV and TB prevention and treatment services, enhancing the capacity of health institutions and ensuring community involvement in the process.
Application Deadline
Oct 4, 2024
Date Added
Aug 6, 2024
The "Critical Facility Energy Resilience (CiFER)" grant aims to fund the development and commercial deployment of innovative energy storage technologies, specifically at sites with identified resiliency needs, to enhance their progress towards commercialization.
Application Deadline
Sep 26, 2025
Date Added
Aug 1, 2023
This funding opportunity supports institutions in creating collaborative training networks for early-career researchers focused on advancing studies in kidney, urologic, and hematologic diseases.
Application Deadline
Dec 8, 2025
Date Added
Jul 29, 2024
This grant provides funding and technical support to innovators and organizations developing sustainable solutions for reusing and repurposing end-of-life products, promoting a circular economy and reducing waste.
Application Deadline
Aug 4, 2025
Date Added
Mar 9, 2023
This funding opportunity provides substantial financial support to higher education institutions and nonprofit organizations to establish collaborative centers that advance research and resources for HIV/AIDS.
Application Deadline
Apr 5, 2025
Date Added
Nov 26, 2024
This funding opportunity is designed to support small businesses in developing innovative medications for treating alcohol use disorder and related organ damage, helping them advance their drug candidates toward FDA approval.
Application Deadline
Oct 17, 2024
Date Added
Dec 14, 2022
Grant Title: Co-infection and Cancer (R01 Clinical Trial Not Allowed) - This grant aims to improve our understanding of how co-infections (excluding HIV) contribute to cancer, particularly in under-studied populations, to identify new prevention and treatment strategies.
Application Deadline
Nov 26, 2025
Date Added
May 28, 2025
This funding opportunity supports organizations in coordinating research efforts to address multiple chronic diseases and reduce health disparities, particularly in underserved communities.
Application Deadline
May 15, 2024
Date Added
Jan 27, 2024
The United States is made up of regional systems comprising interdependent urban and rural systems and every community category between urban and rural. Urban systems and rural systems are interdependent for the provisioning of food, energy sources, water, other materials and natural resources, markets, manufactured goods, and medical resources. These systems are also connected by ecological processes that both influence and are influenced by human behavior. The vital interconnection of urban-rural systems underscores the critical need for the advancement of sustainable regional systems (SRS). The goal of this solicitation is to fund convergent research and education that will advance sustainable regional systems science, engineering, and education to facilitate the transformation of current regional systems to enhance sustainability. To further the advancement of SRS science, engineering, and education, NSF will support proposals for Sustainable Regional Systems Research Networks (SRS RNs). Sustainable regional systems are connected urban and rural systems that are transforming their structures and processes collaboratively with the goal of measurably and equitably advancing the well-being of people and the planet. The purpose of the SRS RNs competition is to develop and support interdisciplinary, multi-organizational teams working collaboratively to produce cutting-edge convergent research, education, and outreach that addresses grand challenges in sustainable regional systems. SRS RNs will study multiscale regional systems to further SRS science, engineering, and education. Key elements will include new data, methods, and models to understand interactions between natural, human-built, and social systems; improved understanding of interdependencies, mutual benefits, and trade-offs of different wellbeing outcomes for humans and the environment; new and generalizable theories of change relevant to SRS;theco-production of knowledge; andexploration of conceptsof social equity in sustainable regional systems across spatial and temporal scales. SRS RN outcomes will have the potential to inform societal actions for sustainability across urban systems and the connected rural communities that make up regional systems. Subject to availability of funds and quality of proposals, this SRS RN solicitation will support: SRS RN Awards.These awards will supportfundamental convergent research, education, and outreach that addressesengineering, chemistry, biology, geosciences, mathematics, statistics, environmental, data, computational, education, and social, behavioral, and economic sciences ofsustainable regional systems in partnerships thatmay embrace universities, colleges, federal, state, and local governments, tribal communities, non-governmental and international bodies, non-profit organizations, industry, practitioners, and other community groups. The award size is up to $15 million totalwith a duration of 5 years. SRS RNs will conduct innovative and pioneering fundamental research and education that is of a scale and complexity that would not be possible within a single organization, center, or through the normal collaborative modes of NSF research support in core programs.
Application Deadline
Oct 28, 2025
Date Added
May 23, 2025
This funding opportunity supports the development of innovative computational tools to analyze complex brain data, inviting a diverse range of researchers and organizations to enhance our understanding of neural circuits and their functions.
Application Deadline
Oct 15, 2024
Date Added
Jun 18, 2024
The DoD Peer Reviewed Cancer, Virtual Cancer Center Director Award is a funding opportunity for established cancer researchers to create and lead a virtual cancer center, which aims to foster collaboration, mentorship, and innovative research among early career investigators across different cancer disciplines, with a focus on convergent science and the development of collaborative seed projects.
Application Deadline
Feb 17, 2026
Date Added
Oct 17, 2025
This grant provides funding to strengthen laboratory and disease monitoring systems in Eswatini, enhancing the country's ability to effectively respond to HIV, tuberculosis, and other public health threats.
Application Deadline
Sep 9, 2024
Date Added
Jul 17, 2024
The Geothermal Resources’ Value in Implementing Decarbonization (GRID) FOA aims to advance the Biden-Harris Administration's goals for a carbon-pollution-free electricity sector by 2035 and a net-zero emissions economy by 2050. The program focuses on regional grid modeling studies to quantify geothermal power's potential contribution to a decarbonized grid. Eligible applicants must submit a Letter of Intent by July 24th, 2024, and full applications by September 9th, 2024. The program offers funding between $500,000 and $1,500,000, with an estimated total funding of approximately $7 million.
Application Deadline
Feb 11, 2025
Date Added
Nov 20, 2024
This funding opportunity supports innovative research projects that aim to improve the use of genomic information in clinical care, particularly for diverse populations, with a focus on health outcomes and addressing disparities.
Application Deadline
Apr 14, 2025
Date Added
Jul 15, 2024
This funding opportunity provides financial support to small rural hospitals and health clinics to help them improve their healthcare services and transition to a value-based care system for better patient outcomes.
Application Deadline
Jan 7, 2025
Date Added
Nov 20, 2024
This funding opportunity provides financial support to early-career researchers in the dental and craniofacial fields to conduct pilot studies that will help them secure larger research grants in the future.


