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Grants for Small businesses - Federal

Explore 1,577 grant opportunities

ERDC Broad Agency Announcement
$999,999,999
U.S. Department of Defense (Engineer Research and Development Center)
Federal

Application Deadline

Jan 1, 2027

Date Added

Jan 5, 2026

This funding opportunity supports innovative research and development projects in various scientific and engineering fields, particularly those that align with military and civil missions, and encourages collaboration among universities, non-profits, and small businesses, including participation from minority institutions.

Science and Technology
Public and State controlled institutions of higher education
Alcohol and Other Substance Use Research Education Programs for Health Professionals (R25 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 25, 2026

Date Added

Aug 1, 2023

This funding opportunity supports innovative educational programs that equip health professionals with the latest research and evidence-based practices related to alcohol and substance use disorders, enhancing patient care and addressing treatment disparities.

Health
State governments
Dissemination and Implementation Research in Health (R03 Clinical Trial Not Allowed)
$50,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2027

Date Added

Oct 31, 2024

This funding opportunity provides financial support for small-scale research projects that aim to improve the adoption and sustainability of evidence-based health practices, particularly in underserved communities, by addressing barriers and engaging diverse stakeholders.

Education
State governments
NINDS Research Education Opportunities (R25 Clinical Trial Not Allowed)
$250,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 14, 2026

Date Added

May 14, 2024

This funding opportunity supports national neuroscience education programs that provide hands-on research experiences and training for graduate students, postdoctoral researchers, and junior faculty to enhance the biomedical research workforce.

Education
Public and State controlled institutions of higher education
NIDA Research Education Program for Clinical Researchers and Clinicians (R25 Clinical Trial Not Allowed)
$350,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 12, 2027

Date Added

Nov 19, 2024

This funding opportunity provides financial support for educational programs aimed at training clinicians and clinical researchers in substance use and substance use disorder research to enhance their skills and research experiences.

Education
State governments
Revision Applications for Validation of Biomarker Assays Developed Through NIH-Supported Research Grants (R01 Clinical Trial Not Allowed)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 14, 2026

Date Added

Oct 11, 2024

This funding opportunity is designed for researchers with active NCI R01 grants to validate and enhance existing cancer biomarker assays, facilitating their clinical use and improving cancer detection and treatment strategies.

Health
Public and State controlled institutions of higher education
Resource-Related Research Projects for Development of Models and Related Materials for Studying Human Health and Diseases (R24 Clinical Trials Not Allowed)
$20,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

May 27, 2026

Date Added

Jun 10, 2025

This funding opportunity supports U.S.-based researchers and institutions in developing innovative experimental models and resources that advance the understanding of human health and diseases across multiple biomedical disciplines.

Health
Public and State controlled institutions of higher education
Coupling, Energetics, and Dynamics of Atmospheric Regions
$750,000
National Science Foundation
Federal

Application Deadline

Mar 3, 2027

Date Added

Mar 21, 2025

This funding opportunity supports U.S.-based educational institutions, research organizations, and qualified entities in conducting innovative research on the dynamics and interactions of Earth's upper atmosphere and its relationship with other planetary atmospheres.

Science and Technology
Public and State controlled institutions of higher education
Research Infrastructure in the Social and Behavioral Sciences
$2,000,000
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Oct 5, 2023

This program provides funding to develop innovative tools and data resources that enhance research capabilities in the social and behavioral sciences, benefiting researchers across various disciplines.

Science and Technology
City or township governments
Cutting-Edge Basic Research Awards (CEBRA) (R21 Clinical Trial Optional)
$150,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 5, 2026

Date Added

Dec 31, 2024

This funding opportunity supports innovative research projects that aim to transform the understanding and treatment of substance use disorders, encouraging bold ideas from both addiction experts and researchers from other fields.

Education
State governments
US Army Combat Capabilities Development Command Broad Agency Announcement
Contact for amount
U.S. Department of Defense (ACC APG - Natick)
Federal

Application Deadline

Feb 27, 2030

Date Added

Jul 15, 2025

This funding opportunity supports innovative research and technological solutions for next-generation soldier technologies, targeting universities, nonprofit research institutions, and commercial firms, excluding government organizations.

Science and Technology
Public and State controlled institutions of higher education
Forecast to Publish a Funding Opportunity Announcement for Copy of Integrative Neuroscience Initiative on Alcoholism (INIA) Consortia Administrative Resource Core (U24) (Clinical Trial Optional)
$1,200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

May 1, 2026

Date Added

May 7, 2025

This funding opportunity supports collaborative research projects focused on understanding the brain and body mechanisms that contribute to excessive alcohol consumption and Alcohol Use Disorder, encouraging innovative approaches and partnerships among researchers.

Health
State governments
Injury Prevention and Control Research and State and Community Based Programs - RFA-IP-18-000
Contact for amount
U.S. Department of Health and Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Sep 30, 2030

Date Added

Oct 20, 2023

This funding opportunity provides financial support for a variety of organizations, including states, universities, and nonprofits, to develop and implement research and community programs focused on preventing and controlling injuries.

Health
State governments
Protecting U.S. Critical Energy Investments Through C-UAS and UAS Surveillance Capabilities in Iraq
$6,808,090
U.S. Department of State (Bureau of Counterterrorism )
Federal

Application Deadline

Jun 8, 2026

Date Added

Apr 15, 2026

This funding opportunity provides financial support to organizations that can help strengthen Iraq's ability to counter drone threats and enhance surveillance capabilities, ultimately protecting U.S. energy investments and personnel in the region.

International Development
Nonprofits
Science of Science: Discovery, Communication and Impact
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

May 9, 2025

This grant provides funding for researchers to explore and improve the processes of scientific discovery, communication, and its impact on society, with a focus on innovative and transformative approaches.

Science and Technology
Nonprofits
Innovation Grants to Nurture Initial Translational Efforts (IGNITE): Development and Validation of Model Systems to Facilitate Neurotherapeutic Discovery (R61/R33 Clinical Trial Not Allowed)
$750,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2027

Date Added

Oct 23, 2024

This funding opportunity provides financial support for research institutions and organizations to develop and validate innovative model systems that can improve the discovery of new treatments for neurological and neuromuscular disorders.

Health
State governments
ROSES25: C.12 Foundational Artificial Intelligence for the Moon and Mars
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Apr 28, 2026

Date Added

Jan 14, 2026

This funding opportunity supports research and development in artificial intelligence technologies to advance NASA's exploration and scientific missions on the Moon and Mars, targeting U.S.-based institutions and international collaborations.

Science and Technology
Public and State controlled institutions of higher education
CHIPS Research and Development Office (CRDO) Broad Agency Announcement (BAA)
Contact for amount
U.S. Department of Commerce (National Institute of Standards and Technology)
Federal

Application Deadline

Sep 30, 2029

Date Added

Sep 25, 2025

This funding opportunity supports U.S. organizations in advancing research and commercialization of microelectronics and related technologies to strengthen domestic innovation and supply chains.

Science and Technology
For profit organizations other than small businesses
ROSES 2025: C.2 Solar System Science
Contact for amount
National Aeronautics and Space Administration (NASA Headquarters)
Federal

Application Deadline

Aug 1, 2026

Date Added

Jul 12, 2025

This grant provides funding for researchers at U.S.-based institutions to conduct innovative studies that enhance our understanding of planetary science and the solar system.

Science and Technology
Public and State controlled institutions of higher education
BRAIN Initiative: Production and distribution facilities for brain cell type-specific access reagents (U24 Clinical Trial Not Allowed)
$2,400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2026

Date Added

Feb 21, 2024

This funding opportunity supports the establishment of facilities that will produce and distribute specialized brain cell access tools for neuroscience research, enabling scientists to better study and manipulate specific brain cell types.

Health
Public and State controlled institutions of higher education