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Grants for Small businesses - Federal

Explore 1,549 grant opportunities

Preclinical Proof of Concept Studies for Rare Diseases (R21 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 9, 2024

This funding opportunity supports research institutions and organizations in conducting preclinical studies to develop new therapies for rare diseases affecting fewer than 200,000 people in the U.S.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for NIDA REI: Reaching Equity at the Intersection of HIV and Substance Use: Novel Approaches to Address HIV Related Health Disparities in Underserved Racial and/or Ethnic Populations (R34)
$2,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 26, 2024

This funding opportunity provides financial support for research projects aimed at developing innovative strategies to reduce HIV-related health disparities among underserved racial and ethnic populations affected by substance use.

Health
Small businesses
Continuation and Expansion of the National Mesothelioma Virtual Bank for Translational Research (U24)
$1,100,000
U.S. Department of Health & Human Services (Centers for Disease Control and Prevention - ERA)
Federal

Application Deadline

Not specified

Date Added

Aug 1, 2025

This funding opportunity provides financial support to institutions that can manage a national virtual registry and tissue bank for mesothelioma research, facilitating access to biospecimens and clinical data for scientific studies.

Health
Public and State controlled institutions of higher education
Risk and Protective Factors of Family Health and Family Level Interventions (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Mar 17, 2025

This funding opportunity supports research on family health and resilience, particularly targeting populations facing health disparities, and is open to a wide range of eligible institutions and organizations.

Education
State governments
Screening, Brief Intervention and Referral to Treatment or Prevention (SBIRT/P) for alcohol, tobacco, and other drugs (ATOD) use and misuse in adult populations that experience health disparities (R01, Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 4, 2025

This funding opportunity supports research projects that develop and test strategies for screening and addressing substance use issues in adult populations facing significant health disparities, with a focus on collaboration and community engagement.

Education
State governments
Innovative Screening Approaches and Therapies for Screenable Disorders in Newborns (R21 - Clinical Trial Optional)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 3, 2024

This funding opportunity supports innovative research projects aimed at improving newborn screening technologies and therapies for genetic disorders, targeting a wide range of eligible organizations and encouraging diverse researchers to apply.

Health
State governments
HEAL NOFO for the HEAL INTERACT Data Center
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

May 14, 2025

This funding opportunity supports collaborative research initiatives aimed at advancing the understanding and treatment of musculoskeletal and peripheral pain, targeting a wide range of eligible organizations, including universities, nonprofits, and government entities.

Health
State governments
AD/ADRD Clinical Trials Short Course
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 28, 2025

This funding opportunity is designed to support the development of training programs that will equip researchers and health professionals with the skills needed to conduct clinical trials focused on Alzheimer’s Disease and related dementias.

Health
For profit organizations other than small businesses
Notice of Intent to Publish a Funding Opportunity Announcement for Impact of Technology and Digital Media Exposure Usage on Child and Adolescent Development
$3,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 26, 2025

This funding opportunity supports research on how technology and digital media impact the development of children and adolescents, inviting applications from a diverse range of institutions and organizations.

Health
State governments
Ethical, Legal and Social Implications (ELSI) Research (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Apr 3, 2025

This funding opportunity supports research on the ethical, legal, and social implications of human genetic and genomic research, encouraging diverse teams to explore issues like data governance, informed consent, and equity in genomic applications.

Education
State governments
Genomic Variant Interactions With Other Variants Or The Environment (UM1 Clinical Trials Not Allowed)
$10,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jun 7, 2025

This funding opportunity supports research on how genetic variations interact with each other and environmental factors to influence biological outcomes, inviting a wide range of institutions and organizations to collaborate on innovative studies.

Health
Native American tribal organizations
Basic Research in Cancer Health Disparities (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports innovative research into the biological and genetic factors contributing to cancer health disparities among racial/ethnic and underserved populations, encouraging collaborative studies that enhance understanding and develop resources to address these issues.

Education
State governments
Catalyze: Product Definition for Small Molecules, Biologics, and Combination Products - Preliminary Product/Lead Series Identification and Combination Product Prototype (R33 - Clinical Trial Not Allowed)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 25, 2024

This funding opportunity provides financial support for higher education institutions, nonprofits, small businesses, and government entities to develop innovative small molecules, biologics, and combination products aimed at treating heart, lung, blood, and sleep diseases.

Health
State governments
Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)
$75,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 17, 2024

This funding opportunity provides financial support to early-career researchers who have received specific NHLBI K awards, allowing them to expand their research projects or explore new studies that build on their previous work.

Health
State governments
Navigator Emergency Department Diversion Models for Non-Urgent Mental Health Concerns (R34 Clinical Trial Required)
$225,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 26, 2024

This funding opportunity supports research projects that develop and test patient navigation models to help divert individuals with non-urgent mental health concerns from emergency departments, aiming to improve access to care and reduce reliance on EDs.

Health
State governments
BRAIN Initiative: New Concepts and Early-Stage Research for Recording and Modulation in the Nervous System (R21) (Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 10, 2024

This grant provides funding for researchers and organizations to develop innovative technologies that can record and manipulate neural activity in the nervous system, with a focus on enhancing precision and scalability in studies involving animals or humans.

Health
State governments
Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
$1,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Dec 31, 2024

This funding opportunity supports preclinical research to identify and test existing drugs or drug combinations for their potential to treat Alzheimer’s Disease and related dementias, encouraging collaboration between academic and industry partners.

Health
State governments
Cellular and Molecular Biology of Complex Brain Disorders (R01 Clinical Trial Not Allowed)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Nov 19, 2024

This funding opportunity supports research into the biological mechanisms behind complex brain disorders, targeting institutions and organizations that can investigate genetic and environmental risk factors to advance therapeutic interventions.

Health
State governments
Small Business Innovation Research (SBIR) program, Phase I
$100,000
U.S. Department of Health and Human Services (Administration for Community Living)
Federal

Application Deadline

Not specified

Date Added

Sep 8, 2025

This funding opportunity supports small businesses in developing innovative research projects that improve the quality of life for individuals with disabilities.

Science and Technology
Small businesses
National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental Disorders (U19 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Jan 16, 2025

This funding opportunity supports collaborative research teams in developing innovative drugs and devices to improve treatments for mental health disorders.

Health
State governments