GrantExec

Grants for Small businesses - Federal

Explore 1,501 grant opportunities

Notice of Intent (NOI) DE-FOA-0003607, is to Issue Notice of Funding Opportunity (NOFO) No. DE-FOA-0003606, titled, "Improving Efficiency, Reliability, and Flexibility of Coal-Based Power Plants"
$50,000,000
U.S. Department of Energy (National Energy Technology Laboratory)
Federal

Application Deadline

Oct 31, 2025

Date Added

Oct 7, 2025

This funding opportunity is designed to support research and projects that improve the efficiency and environmental performance of existing coal power plants in the U.S., targeting energy companies and technology developers focused on enhancing grid reliability and reducing emissions.

Energy
State governments
Development of Biomarkers or Composite Biomarkers for Neurological and Neuromuscular Disorders (R61/R33 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Oct 29, 2024

This funding opportunity supports researchers and organizations in developing and validating biomarkers for neurological and neuromuscular disorders to improve clinical trials and patient care.

Health
State governments
Manufacturing Systems Integration
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Jan 3, 2025

This grant provides funding for researchers and organizations to explore innovative digital technologies that improve the integration and efficiency of manufacturing systems, fostering collaboration and advancing industry competitiveness.

Science and Technology
For profit organizations other than small businesses
NIH Exploratory/Developmental Research Project Grant (Parent R21 Basic Experimental Studies with Humans Required)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 16, 2025

Date Added

Dec 19, 2024

This funding opportunity supports research aimed at understanding how HIV-related changes in the immune system affect the risk of tuberculosis and hepatitis B in individuals undergoing treatment, encouraging innovative approaches and collaboration among diverse research teams.

Education
State governments
Training-based Workforce Development for Advanced Cyberinfrastructure (CyberTraining)
$1,000,000
National Science Foundation
Federal

Application Deadline

Jan 15, 2026

Date Added

May 22, 2025

This grant provides funding to educational institutions and researchers to develop innovative training programs that enhance the use of advanced cyberinfrastructure tools and methods, particularly for underrepresented groups in science and engineering.

Science and Technology
Public and State controlled institutions of higher education
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Clinical Trials (UH3 Clinical Trial Optional)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2025

Date Added

Jun 10, 2025

This funding opportunity supports U.S. institutions conducting clinical trials on innovative regenerative medicine therapies using adult stem cells, focusing on extending research from previously funded projects.

Health
State governments
NIDCD Research Grants for Translating Basic Research into Clinical Practice (R01 Clinical Trial Optional)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 13, 2025

Date Added

Dec 17, 2024

This funding opportunity supports collaborative research projects that translate basic scientific discoveries into practical clinical applications for diagnosing and treating communication disorders, encouraging partnerships between scientists and clinicians.

Health
State governments
FreeSol Broad Agency Announcement
$99,000,000
U.S. Department of Defense (Space Systems Command)
Federal

Application Deadline

Feb 23, 2029

Date Added

Oct 6, 2025

This grant provides funding for innovative research and development projects that enhance U.S. space and cyber technologies, targeting businesses, universities, and research institutions focused on improving space domain awareness and combat capabilities.

Science and Technology
For profit organizations other than small businesses
Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional)
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 20, 2025

Date Added

Oct 31, 2024

This funding opportunity provides financial support for innovative research projects that explore the complex relationship between adolescent social media use and mental health, particularly focusing on underserved youth populations.

Health
State governments
Screening and Functional Validation of Genomic Variants Associated with Human Congenital Anomalies (R01 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Oct 31, 2024

This grant provides funding for researchers to investigate and validate genetic variants linked to congenital anomalies, aiming to improve understanding and treatment of these conditions.

Health
State governments
Resource-based Centers for Bone, Muscle and Orthopaedic Research
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Nov 3, 2025

Date Added

May 28, 2025

This funding opportunity is designed to support the establishment of collaborative research centers that enhance the study and treatment of bone, muscle, and orthopaedic conditions through shared resources and multidisciplinary approaches.

Health
State governments
Devcom Army Research Laboratory Broad Agency Announcement For Foundational Research
Contact for amount
U.S. Department of Defense (Dept of the Army -- Materiel Command)
Federal

Application Deadline

Nov 20, 2027

Date Added

Nov 21, 2022

This grant provides funding for researchers and organizations to conduct foundational and applied scientific research that supports the U.S. Army's mission to maintain technological superiority in future conflicts.

Science and Technology
Nonprofits
NHLBI SBIR Phase IIB Small Market Awards to Accelerate the Commercialization of Technologies for Heart, Lung, Blood, and Sleep Disorders and Diseases (R44 Clinical Trial Optional)
$2,333,333
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 26, 2026

Date Added

Nov 20, 2024

This funding opportunity supports small businesses developing innovative technologies for rare diseases and pediatric populations, helping them bridge the gap between research and commercialization.

Health
Small businesses
Community-Partnered Nursing Research Centers (P20 Clinical Trial Optional)
$500,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 25, 2026

Date Added

May 6, 2025

This funding opportunity provides financial support for nursing schools and community organizations to collaborate on research projects that address health challenges and improve well-being in local populations.

Health
Public and State controlled institutions of higher education
Infrastructure Cluster
Contact for amount
National Science Foundation
Federal
Rolling

Application Deadline

Not specified

Date Added

Sep 26, 2024

This grant provides funding and support for researchers and institutions involved in atmospheric and geospace sciences, facilitating access to advanced facilities, data, and instruments for scientific study.

Science and Technology
Private institutions of higher education
Advancing Healthcare for Older Adults from Populations that Experience Health Disparities (R01 - Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 7, 2028

Date Added

Aug 28, 2024

This funding opportunity supports research projects aimed at improving healthcare for older adults from underserved populations, focusing on reducing health disparities and enhancing patient-centered care.

Education
State governments
Collaboration for Innovative Research on Aircraft Structure (CIRAS)
$6,000,000
U.S. Department of Defense (Air Force -- Research Lab)
Federal

Application Deadline

May 11, 2026

Date Added

May 11, 2021

This funding opportunity supports research and development projects focused on creating innovative and efficient aircraft structures, open to a wide range of applicants including universities, businesses, and non-profits.

Science and Technology
For profit organizations other than small businesses
Limited Competition: Regenerative Medicine Innovation Project (RMIP) Investigator-Initiated Studies (U01 Clinical Trial Not Allowed)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 21, 2025

Date Added

Jun 10, 2025

This funding opportunity supports late-stage preclinical studies using adult stem cells to advance regenerative medicine therapies, specifically for researchers who have previously received NIH funding in this area.

Health
State governments
Science of Learning and Augmented Intelligence (SL)
Contact for amount
National Science Foundation
Federal

Application Deadline

Feb 11, 2026

Date Added

Aug 23, 2024

This funding opportunity supports researchers exploring how learning processes can be enhanced through technology and collaboration, aiming to advance our understanding of cognitive functions and their applications across various fields.

Science and Technology
Public and State controlled institutions of higher education
ECosystem for Leading Innovation in Plasma Science and Engineering
Contact for amount
National Science Foundation
Federal

Application Deadline

Dec 5, 2025

Date Added

Aug 21, 2024

This funding initiative provides support for innovative research that connects fundamental plasma science with practical applications in technology and society, particularly encouraging participation from underrepresented communities and institutions.

Science and Technology
Public and State controlled institutions of higher education