Grants for Small businesses - Federal

This grant provides funding for innovative technologies that improve the Navy and Marine Corps' electronic warfare and surveillance capabilities, targeting researchers and companies developing advanced signal processing, countermeasures, and ISR systems.

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits applications for identification of small molecules that function to elucidate the biology of disease as chemical probes or function as agonists or antagonists of disease target(s) for therapy or immunotherapy. The NOFO is intended to support discovery research for the identification of validated hits relevant to health-related outcomes of participating NIH Institutes. Stages of discovery research covered by this NOFO include: 1) assay development for specific biological targets and disease mechanisms relevant to the mission of participating NIH Institutes with the intent to screen for small molecule compounds that show potential as probes for use in advancing knowledge about the known targets, identifying new targets, or as pre-therapeutic leads; 2) screen implementation high throughput target-focused approaches or moderate throughput phenotypic- and fragment-based approaches to identify initial screening hits; 3) hit validation, including implementation of secondary assays that are orthogonal to the primary assay, advanced cheminformatics analysis and initial medicinal chemistry inspection to prioritize the hit set, and follow-up assays to characterize mode and mechanism of action of the validated hits; 4) hit-to-lead optimization, including SAR to optimize target engagement, selectivity and to minimize chemical liabilities, ADME, PK and PD studies, and, if appropriate, in vivo modeling to test efficacy or biological effects.

This funding opportunity provides financial support for researchers to analyze existing data on late talking children, particularly focusing on underrepresented populations, to better understand their developmental trajectories and improve language outcomes.

With this solicitation, OJJDP seeks to support states implementation of innovative and/or research-based, data-informed policies to improve juvenile justice system outcomes and sustainable strategies for reinvesting resulting costs saved or averted into effective delinquency prevention and intervention programs.Eligibility This solicitation is composed of two grant categories. Applicants must clearly designate the category for which they are applying. Category 1: Juvenile Justice System Reform State governments Category 2: Juvenile Justice System Reform Training and Technical Assistance Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education Public- and state-controlled institutions of higher education Private institutions of higher education For-profit organizations other than small businesses Small businesses

The Rural Energy for America Program (REAP) provides guaranteed loan financing and grant funding to agricultural producers and rural small businesses in Idaho for renewable energy systems and energy efficiency improvements. Eligible entities include agricultural producers with at least 50% income from agricultural operations and small businesses in rural areas, meeting specific criteria. The program supports a range of projects, including biomass, geothermal, hydropower, wind, and solar energy systems, as well as energy efficiency upgrades. Applications are accepted year-round, with specific deadlines for fiscal years 2023 and 2024.

This grant provides funding for early-phase clinical trials aimed at improving treatments for service-connected eye injuries and visual dysfunction in military personnel and veterans.

This funding opportunity supports clinical research to explore and validate new non-invasive brain stimulation techniques for treating substance use disorders, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

This program provides financial and technical support to private landowners and communities for restoring and conserving fish and wildlife habitats on private lands, benefiting endangered species and promoting biodiversity.

The PRMRP Technology/Therapeutic Development Award (TTDA) is a product-driven award mechanism intended to provide support for the translation of promising preclinical findings into products for clinical applications, including prevention, detection, diagnosis, treatment, or quality of life, for a disease or condition related to one of the FY24 PRMRP Topic Areas and one of the FY24 PRMRP Strategic Goals. Products in development should be responsive to the health care needs of military Service Members, Veterans, and their Families. The product(s) to be developed under the PRMRP TTDA mechanism may be a tangible item, such as a pharmacologic agent (drugs or biologics) or device, or a knowledge-based product. (A knowledge product is a non-materiel product that addresses an identified need in a topic area, is based on current evidence and research, aims to transition into medical practice, training, tools, or to support materiel solutions [systems to develop, acquire, provide, and sustain medical solutions and capabilities], and educates or impacts behavior throughout the continuum of care, including primary prevention of negative outcomes.)The Technology/Therapeutic Development Award is not intended for basic research. Applicants generating preliminary data, basic research, performing high-risk/high-gain studies should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.

This funding opportunity supports collaborative research on the long-term effects of adolescent alcohol use on brain function and behavior, inviting diverse institutions and organizations to participate in advancing treatment and prevention strategies for alcohol use disorders.

This funding opportunity supports U.S.-based small businesses in developing innovative, non-addictive therapies and technologies for improved pain management, addressing the opioid crisis through preclinical research and technological advancements.

CSO announces an open competition for organizations interested in submitting applications for programs that support increasing the capacity of a cohort of civil servants within the Republic of Yemen Government (ROYG) to identify priorities for the development of inclusive stabilization plans.

This grant provides funding for researchers, especially early-career scientists and students, to develop and test new technologies for studying solar and space physics through low-cost suborbital flights.

This funding opportunity supports the development of innovative therapies to counteract the effects of Botulinum Neurotoxin, targeting researchers and organizations focused on advancing treatments for this serious health threat.

This funding opportunity provides financial support to organizations working in Namibia to improve health information systems and enhance public health programs related to HIV, tuberculosis, and other health threats.

This funding opportunity supports early postdoctoral fellows from diverse backgrounds in cancer research, providing mentorship and training to help them address health disparities and advance their careers in the field.

Reissue PAR-21-122. This NOFO provides funding to conduct pharmacodynamic, pharmacokinetic, and in vivo efficacy studies to demonstrate that proposed therapeutic agent(s) have sufficient biological activity to warrant further development to treat neurological or neuromuscular disorders that fall under the NINDS mission. Therapeutic agents include small molecules, biologics or biotechnology-derived products. This FOA is part of a suite of Innovation Grants to Nurture Initial Translational Efforts (IGNITE) to advance projects to the point where they can meet the entry criteria for the Blueprint Neurotherapeutics Network or other translational programs.

The United States Agency for International Development Mission in Indonesia (USAID/Indonesia) posts this Request for Information (RFI) to inform interested parties of an upcoming health system strengthening (HSS) activity designed to improve accountability, health system performance and health outcomes (especially for Maternal and Child Health, Tuberculosis, HIV, and Global Health Security) based on performance-based and sustainable health financing, a strengthened health information system, resilient human resources for health, integrated care models, and a strong evidence to policy pathway.This Request for Information (RFI) is issued solely for information gathering purposes and is published in accordance with FAR Part 10 and FAR Part 15.201(e).Through this RFI, USAID/Indonesia seeks to enhance the design of the HSS Flagship Activity in Indonesia. This RFI seeks information from capable organizations (i.e., nongovernmental organizations, universities, consortium, for-profit, and local organizations) that are implementing or have implemented HSS projects that spans more than one health system building block and may be interested to partner with USAID in achieving the goals of this future HSS activity. All capable organizations are encouraged to respond.This RFI does not constitute a Request for Applications (RFA) or a Request for Proposals(RFP). Responses to this RFI are not applications or official proposals and will in no way be deemed to form any binding agreement with the RFI issuing authority. Please do not submit applications, proposals, budget, costs, resumes or promotional materials, as they will be discarded. Proprietary information should not be sent. USAID may use any information provided without incurring any obligation. USAID reserves the right to, or not to incorporate any, some, or none of the comments received from this RFI into any subsequent solicitations or design documents.(See further information in Related Documents Tab)

The 80MSFC24M0001 Cooperative Agreement Notice is a grant aimed at fostering partnerships with U.S. industry and academic/non-profit organizations to develop technologies that enhance the commercial space sector, support future NASA missions, and promote the U.S. as a leader in aeronautical and space science, with financial support provided by NASA.

This funding opportunity provides financial support for research projects that explore and improve crisis response services for suicide prevention, particularly targeting diverse and underserved populations.