Grants for Small businesses - Federal

This Funding Opportunity Announcement (FOA) encourages research grant applications directed toward developing next-generation human cell-derived microphysiological systems (MPS) and related assays that replicate complex nervous system architectures and physiology with improved fidelity over current capabilities. Supported projects will be expected to enable future studies of complex nervous system development, function and aging in healthy and disease states.

This funding opportunity supports clinical trials aimed at improving treatments and care for individuals with amyotrophic lateral sclerosis (ALS), encouraging collaboration with patients and caregivers in the research process.

The "Knowledge SUCCESS II" grant is intended to enhance the integration of Knowledge Management (KM) into global health and development programs, aiming to improve accessibility, engage marginalized groups, and achieve better outcomes by serving stakeholders like health officials, advisors, and donor staff.

The ERP seeks to solicit Faculty members to join the Virtual Post-Traumatic Epilepsy Research Center (P-TERC) in order to advance PTE research through development of early-career investigators and investigators new to the PTE field. The ERP Virtual P-TERC is a unique, interactive virtual research center providing intensive mentoring, national networking, collaborations, and a peer group for new PTE investigators. The overarching goal of the Virtual P-TERC is to develop successful, highly productive PTE researchers in a collaborative research and career development environment to enhance quality and expand quantity of the PTE research field. The Virtual P-TERC is a multi-institutional career development and research training platform that consists of Faculty and their Career Guides (primary mentors) and is managed by a Director and Deputy Director. The Virtual P-TERC Leadership (the Director and the Deputy Director) serve as a resource for the Faculty and Career Guides, assessing the progress of Faculty and facilitating communication and collaboration among all of the Faculty and Career Guides, as well as with national research societies and representatives from the community with lived PTE experience. In addition to fostering scientific development, the Virtual P-TERC, through its Leadership, provides for professional and leadership development of the Faculty to include skills and competencies needed to fund and manage a productive PTE research laboratory.

The FY24 PRMRP Impact Award supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research, and insights from the real-world environment, to foster clinical applicability. The intent of the Impact Award is to translate the fundamental understanding of underlying mechanisms toward practical applications that have the potential for major near-term impact on patients affected by one of the diseases and conditions included in the FY24 PRMRP Topic Areas.Proposed research should refine mature concepts and ideas into translatable solutions with a view toward evaluating technical feasibility of promising new pharmacological agents, knowledge products, behavioral and rehabilitation interventions, diagnostic and therapeutic techniques, clinical guidance, and/or emerging approaches and technologies. The FY24 PRMRP Impact Award is not intended to support basic research.For the purposes of this funding opportunity, basic research is defined as exploratory science directed toward greater knowledge or understanding of the fundamental aspects of phenomena or outcomes, without specific applications toward process and products. Examples include, but are not limited to, high-risk/high-gain approaches, mechanistic studies, and preliminary data generation/validation. Applicants seeking funding for research that meets this definition should consider one of the other FY24 PRMRP program announcements being offered. For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.Pre-Application (Letter of Intent) Submission Deadline: 5:00 p.m. Eastern time (ET), May 13, 2024

The SCIRP IIRA is intended to support studies that have the potential to make an important contribution to SCI research, patient care, and/or quality of life.Important aspects of this award mechanism include: Impact: Applications should articulate the short- and long-term impact of the proposed research on both the SCI research field as well as the SCI community. Projects must address one or more of the FY24 SCIRP Focus Areas. Relevance to Military Health: Projects should be relevant to spinal cord-injured military Service Members, Veterans, and/or their Family members and care partners. Collaboration with military and VA researchers and clinicians is encouraged. Preliminary Data: Observations that drive a research idea may be derived from laboratory discovery, population-based studies, a clinicians first-hand knowledge of patients, or anecdotal data. Applications must include preliminary and/or published data that are relevant to the mission of the SCIRP and support the proposed research project.IIRA applications may focus on any phase of research from basic through translational, though studies focused exclusively on target identification are discouraged. Permitted research includes preclinical studies in animal models (except where otherwise specified), research with human subjects or human anatomical substances, as well as ancillary studies associated with an existing clinical trial.

This funding opportunity provides resources to develop a standardized training curriculum for new corrections staff to effectively prevent and respond to sexual abuse and harassment in various confinement facilities across the country.

This funding opportunity supports early-stage researchers in the U.S. who are pursuing innovative and high-impact projects in infectious, immunologic, and allergic diseases, without requiring extensive preliminary data.

This funding opportunity supports the development of innovative technologies that improve the collection and preservation of biological samples for cancer research and clinical care, targeting a wide range of eligible applicants including universities, nonprofits, and small businesses.

This funding opportunity supports early stage researchers in pursuing innovative and high-risk scientific projects that significantly diverge from their previous work, without the need for preliminary data.

This funding opportunity supports long-term, investigator-led clinical trials aimed at advancing research in allergy, infectious diseases, and aging, available to a wide range of eligible institutions both in the U.S. and internationally.

The National Institute of Neurological Disorders and Stroke (NINDS), in collaboration with the National Institute of Mental Health (NIMH), intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications that propose the development and early stage validation of novel humanized small animal models and/or human cellular microphysiological systems for NeuroHIV preclinical research. The goal of this initiative is to promote a significant improvement in the translational relevance of NeuroHIV models, specifically in the context of chronic HIV infection of the central nervous system (CNS) in the modern antiretroviral therapy (ART) era under conditions of viral suppression. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Summer 2024 with an expected application due date in Fall 2024. This NOFO will utilize the R61/R33 activity code. Details of the planned NOFO are provided below.

The U.S. Department of State, Bureau of Democracy, Human Rights, and Labor (DRL) announces an open competition for organizations interested in advancing freedom of association and improving working conditions in the palm oil sector in Indonesia.

This funding opportunity supports researchers and institutions developing innovative organ-on-a-chip technologies to advance disease modeling and preclinical studies in dental, oral, and craniofacial health.

The United States Agency for International Development (USAID) is seeking applications for a Cooperative Agreement with a Total Estimated Amount of $45,000,000 from qualified entities to implement the program entitled Strengthening Integrated Health Services Activity (SIHSA) in Sierra Leone.USAID anticipates awarding a five-year cooperative agreement (CA) to advance and sustain improved health outcomes for Sierra Leoneans with a focus on, but not limited to: children under five, pregnant and postpartum women, youth and especially adolescent girls, and women and children living in hard-to-reach areas with limited access to health services. Special attention will be paid to those especially vulnerable within these groups, such as the disabled, gender andsexual minorities (GSM), and ethnic and religious minorities.SIHSA seeks to build a sustainable and resilient health system response to improving access, quality, and effectiveness of family planning (FP), reproductive health (RH), maternal, newborn and child health (MNCH), adolescent health, and malaria services. In addition, SIHSA aims at strengthening communities;apos; active engagement for community-driven solutions to improve health outcomes. Finally, SIHSA seeks to promote a paradigm shift within the health system, supporting system-wide action, especially at community and district levels, including reforms that act on the foundations of the health system and create opportunities for partnering with the local civil society and private sector for improved health outcomes.

This funding opportunity supports innovative research projects that improve the early diagnosis and prognosis of Alzheimer’s disease and related dementias, emphasizing community collaboration and inclusivity for underrepresented populations.

With this solicitation, BJA is seeking applications to support DOJs Global Justice Information Sharing Initiative (Global) to engage the full range of criminal justice policymakers and practitioners in the development of innovative strategies to improve the justice information and criminal intelligence sharing and technology capabilities of state, local, Tribal, territorial agencies and associated disciplines.

This grant provides funding for research projects that develop and validate clinical outcomes and biomarkers to improve the understanding and treatment of Amyotrophic Lateral Sclerosis (ALS), with a focus on community collaboration and non-interventional studies.

The goals of the paleoclimate program are to: (i) provide a baseline for present climate variability and future climate trends, and (ii) improve the understanding of the physical, chemical, and biological processes that influence climate variability and trends over the long-term. Research topics include observational and modeling studies of past climate variability and its drivers and studies that develop new paleoclimate proxies and records. Competitive proposals will address specific aspects of scientific uncertainty for their proposed research. The Paleoclimate program of the Division of the Atmospheric and Geospace Sciences together with other Divisions in the Geoscience Directorate have joined in coordinating and supporting the annual Paleo Perspectives on Present and Projected Climate (P4CLIMATE) competition with the objectives to support studies within two research themes: 1) Past Regional and Seasonal Climate; and 2) Past Climate Forcing, Sensitivity, and Feedbacks. Researchers are encouraged to consider the P4CLIMATE competition as a possible source of support for their global change research. Since proposals eligible for funding in the P4CLIMATE competition are not eligible for funding in the Paleoclimate Program, researchers are strongly advised to contact the Directors of the Paleoclimate Program for guidance as to the suitability of their proposed research for either program. The paleoclimate program strongly encourages proposals from: Researchers at all career stages, including through the AGS Postdoctoral Research Fellowship program. Researchers at all institution types, including MSIs, non-R1 institutions, and institutions in EPSCoR jurisdictions. Researchers from traditionally underrepresented groups in Paleoclimate Science.

Grant Title: Ending the Epidemic: New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services (R34 Clinical Trial Optional) aims to support the development and testing of integrated healthcare models that combine HIV/AIDS, Hepatitis, addiction treatment, and primary care services to improve health outcomes for individuals at risk for or living with these conditions.