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Grants for Small businesses - Federal

Explore 1,532 grant opportunities

Precision Approaches in Radiation Synthetic Combinations (PAIRS, R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jun 5, 2025

Date Added

Jun 14, 2022

This funding opportunity supports research projects that explore innovative combinations of radiation therapy and other treatments to improve cancer care, inviting applications from a diverse range of organizations, including universities, nonprofits, and for-profit entities.

Education
State governments
Genome Research Experiences to Attract Talented Undergraduates into Genomic Fields to Enhance Diversity (R25 Clinical Trial Not Allowed)
$350,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jul 1, 2024

Date Added

Jun 25, 2024

The NIH Research Education Program (R25) supports research education activities in the mission areas of the NIH. The overarching goal of this NHGRI R25 program is to support educational activities that encourage undergraduates from diverse backgrounds, including those from groups underrepresented in the biomedical workforce, to pursue further training and careers in the scientific, medical, ethical, social and/or legal areas of genomics research. To accomplish the stated over-arching goal, this FOA will support creative educational activities with a primary focus on: Research Experiences Courses for Skills Development This Genome Research Experiences to Attract Talented Undergraduates into the Genomic Field to Promote Diversity (GREAT) Program will support collaborative institutional partnerships that provide research education programs for undergraduates enrolled at minority-serving institutions (MSIs) or Institutional Development Award (IDeA)-eligible institutions. A partnership will include a MSI or IDeA-eligible institution, and one or more research-intensive institutions or organizations with a suitable research base for graduate-level training in scientific areas of interest to NHGRI.

Health
Public and State controlled institutions of higher education
Advancing Genomic Medicine Research (R03 Clinical Trial Not Allowed)
$500,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 11, 2025

Date Added

Nov 20, 2024

This funding opportunity supports small-scale research projects that aim to improve the use of genomic information in clinical care, particularly for diverse and historically underrepresented populations.

Health
State governments
Frontier Health Markets Annual Program Statement
Contact for amount
U.S. Agency for International Development
Federal

Application Deadline

Feb 24, 2028

Date Added

Feb 25, 2021

This funding opportunity is designed to enhance health services by engaging the private sector to improve family planning, maternal and child health, and control infectious diseases in various communities.

Health
Nonprofits
NSF Small Business Innovation Research / Small Business Technology Transfer Phase II Programs
$1,250,000
National Science Foundation
Federal

Application Deadline

Nov 5, 2025

Date Added

Jun 2, 2025

This grant provides funding to small businesses and startups that have previously received NSF Phase I awards, helping them advance their innovative research into market-ready products and services.

Science and Technology
Small businesses
In Vivo Non-Invasive Optical Imaging Approaches for Biological Systems (UG3/UH3 Clinical Trials Not Allowed
$4,900,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 7, 2025

Date Added

Dec 3, 2024

This funding opportunity supports U.S.-based institutions and organizations in developing innovative non-invasive optical imaging technologies for biological research and clinical applications, with a focus on improving imaging depth and resolution.

Health
Public and State controlled institutions of higher education
NOAA Small Business Innovation Research (SBIR) Program- FY25 Phase I
$190,000
U.S. Department of Commerce (DOC NOAA - ERA Production)
Federal

Application Deadline

Jan 15, 2025

Date Added

Nov 18, 2024

This grant provides funding for small businesses to develop innovative technologies that support NOAA's mission in areas like climate change, coastal resilience, and water quality.

Science and Technology
Small businesses
Emerging Health Innovators (EHI) Initiative
$350,000
U.S. Department of Health & Human Services (Advanced Research Projects Agency for Health)
Federal

Application Deadline

Feb 5, 2025

Date Added

Jan 7, 2025

This initiative provides funding to early-career researchers and community organizations to develop innovative health solutions that address critical health challenges in local communities.

Science and Technology
Public and State controlled institutions of higher education
Tribal Colleges and Universities Program Hub and Topical Interest Groups
$17,500,000
National Science Foundation
Federal

Application Deadline

May 31, 2024

Date Added

Feb 22, 2024

This solicitation is offered for support of two types of projects, a TCUP Hub and faculty-led topical interest groups (TIGs). The TCUP Hub will serve the entire TCUP-eligible community with activities such as convening workshops (including the TCUP Leaders' Forum), coordinating faculty/student exchanges, organizing professional development opportunities, and overseeing TCUP Fellowship opportunities with eligible agencies. The Hub will connect people and organizations to facilitate relationships, expand and diversify networks, and support TCUP faculty and staff in building capacity in areas they identify. It will curate shared resources, expertise, and experiences to build the capacity of TCUP institutions. Also, it will build and support a sense of community among all TCUP institutions and elevate the voices within them. Only one Hub will be supported, either to a single institution or to a collaborative submission from multiple institutions. Interested parties may find that a collaborative submission from multiple institutions is more feasible, engaging two or more TCUP institutions to synergistically leverage their different strengths in realizing the Hub's mission. Multiple institutions submitting collaboratively may better address the multiplicity of TCUP institutions, which vary geographically, administratively, and in modes of governance. Clearly, some activities may be best pursued by enlisting specialists as consultants. Two types of collaborative proposals are acceptable: simultaneous submission of proposals from multiple organizations submitting a unified set of certain proposal sections, as well as information unique to each organization, such as unique budgets, key personnel, and activities; or submission of a collaborative proposal from one organization, with collaborating institutions included through subawards (subawards are permitted only to TCUP-eligible institutions; proposers should confer with the TCUP program staff prior to submission). All collaborative proposals submitted from multiple organizations must be submitted via Research.gov. Additionally, this solicitation is offered for support of independent, faculty-led topical interest groups (TIGs) that focus on professional development of faculty and formation of science, technology, engineering, and mathematics (STEM) discipline networks (e.g., engineering, genomics, Indigenous research, environmental science). Up to two new TIGs may be supported. [1] Executive Order 13021 defines Tribal Colleges and Universities ("tribal colleges") as those institutions cited in section 532 of the Equity in Educational Land-Grant Status Act of 1994 (7 U.S.C. 301 note), and other institutions that qualify for funding under the Tribally Controlled Community College Assistance Act of 1978, (25 U.S.C. 1801 et seq.), as well as Navajo Community College as authorized in the Navajo Community College Assistance Act of 1978, Public Law 95-471, Title II (25 U.S.C. 640a note). The term "Alaska Native-serving institution" means an institution of higher education that is an eligible institution under section 1058(b) of the Higher Education Act; and that, at the time of submission, has an undergraduate enrollment that is at least 20 percent Alaska Native students. The term "Native Hawaiian-serving institution" means an institution of higher education that is an eligible institution under section 1058(b) of the Higher Education Act; and that, at the time of submission, has an undergraduate enrollment that is at least 10 percent Native Hawaiian students. Most TCUP-eligible institutions of higher education are two-year or community colleges. See the Who May Submit Proposals section in this solicitation for further details.

Science and Technology
Public housing authorities
to Publish a Notice of Funding Opportunity (NOFO) for the Rare Diseases Clinical Research Consortia (RDCRC) for the Rare Diseases Clinical Research Network (RDCRN)
$1,000,000
HHS-NIH11 (National Institutes of Health)
Federal

Application Deadline

Jun 14, 2024

Date Added

May 22, 2023

The National Center for Advancing Translational Sciences (NCATS) intends to publish aNotice of Funding Opportunity (NOFO) to solicit applications for research to advance the diagnosis, management, and treatment of rare diseases. Each Rare Diseases Clinical Research Consortium (RDCRC) will promote highly collaborative, multi-site, patient-centric, translational, and clinical research. It is strongly encouraged that the RDCRC study outcome measures include those that address unmet clinical trial readiness needs that will move the field of research forward from its current state. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in winter 2024, with an expected application due date in summer 2024. This NOFO will utilize the U54 activity code, which supports specialized centers through multi-project cooperative agreement awards to support research activities with substantial involvement from NIH program staff. Details of the planned NOFO are provided below.

Health
State governments
Notice of Intent to Publish a Funding Opportunity Announcement for Annual Conference in Therapeutics Development for Substance Use Disorders (U13 Clinical Trial Not Allowed)
$100,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 20, 2025

Date Added

Nov 26, 2024

This funding opportunity supports organizations in planning and hosting an annual conference focused on advancing the development of treatments for substance use disorders, bringing together researchers, clinicians, and policymakers to foster collaboration and innovation in this critical public health area.

Health
State governments
Implementation of integrated, resilient, and sustainable health systems for HIV/TB epidemic control in the Republic of Kenya under the President's Emergency Plan for AIDS Relief (PEPFAR)
$6,000,000
U.S. Department of Health & Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 19, 2025

Date Added

Jul 18, 2024

This funding opportunity provides financial support to a range of organizations working in Kenya to strengthen health systems for effective management and control of HIV and TB, while promoting sustainable healthcare practices and improving public health responses.

Health
State governments
Developmental Centers for AIDS Research (P30 Clinical Trial Not Allowed)
$1,000,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 4, 2025

Date Added

Mar 9, 2023

This funding opportunity provides significant financial support to U.S. higher education institutions and research organizations with established HIV/AIDS research programs, enabling them to enhance their research infrastructure and foster interdisciplinary collaboration in the fight against HIV/AIDS.

Education
State governments
Capacitating Investigative Journalism in Botswana
$100,000
U.S. Department of State (U.S. Mission to Botswana)
Federal

Application Deadline

Sep 13, 2024

Date Added

Aug 13, 2024

U.S. Embassy Gaborone of the U.S. Department of State announces an open competition for organizations to submit proposals to carry out a program to train investigative journalists in Botswana, capacitate training cohort participants in developing and writing/producing, and publishing well-researched investigative news stories that serve the public interest, and develop newsroom financial and management capacity that supports a robust, ethical, and sustainable independent news media environment in Botswana

International Development
Nonprofits
Fiscal Year 2024 Solar Energy Supply Chain Incubator FOA
$6,000,000
U.S. Department of Energy (Golden Field Office)
Federal

Application Deadline

Oct 7, 2024

Date Added

Jun 11, 2024

The U.S. Department of Energy (DOE) Solar Energy Technologies Office (SETO) announced the Fiscal Year 2024 Solar Energy Supply Chain Incubator funding opportunity (FOA), which will provide up to $50.5 million for research, development, and demonstration (RD) projects that de-risk solar hardware, manufacturing processes, and software products across a wide range of solar technology areas. The research and development (R) and demonstration (RD) activities to be funded under this FOA will support the government-wide approach to the climate crisis by driving the innovation that can lead to the deployment of clean energy technologies, which are critical for climate protection. Specifically, this FOA will support the DOE decarbonization goals by advancing innovative solar hardware, software, and manufacturing processes across a broad range of technology readiness levels, from laboratory-scale to pilot-scale testing and prototype demonstration. Technologies of interest include photovoltaics (PV), systems integration, and concentrating solar-thermal power (CSP) technologies, as well as those that connect solar with storage or electric vehicles and dual-use PV applications like agrivoltaics and vehicle-integrated PV. SETO encourages for-profit applicants to team with diverse institutions including academic institutions, non-profits, state and local governments, and Tribal governments. The FOA also seeks projects that provide outreach, education, or technology development for software that delivers an automated permit review and approval process for rooftop solar PV with or without energy storage. Both for-profit and non-profit entities are eligible to apply under this topic. SETO expects to make between 11 and 23 awards ranging from $1 million to $6 million under this FOA. Learn more about past Incubator funding program awardees. Prior to submitting a full application for this opportunity, a mandatory concept paper is due July 19 at 5 p.m. ET. Applicants can also access free Application Education Services through the American-Made Network and can engage with Power Connectors.

Energy
Nonprofits
Grid Reliability With Automatic Damping And Inertia For Electrical Networks And Transmission Systems Sbir/STTR (Gradients Sbir/STTR)
$4,505,859
U.S. Department of Energy (Advanced Research Projects Agency Energy )
Federal

Application Deadline

Feb 14, 2025

Date Added

Jan 15, 2025

This funding opportunity supports small businesses developing innovative technologies to improve the stability and reliability of electrical grids as renewable energy sources become more prevalent.

Opportunity Zone Benefits
Small businesses
DOD Neurofibromatosis, Neurofibromatosis Research Academy Leadership Award
$1,500,000
DOD-AMRAA (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Sep 12, 2024

Date Added

Jun 4, 2024

To increase research capacity for NF, the NFRP is offering the NFRA. The intent of the NFRA is to provide a framework of intensive mentoring and iterative guidance with proposed research, national networking, collaborations, and a peer group of junior faculty (Scholars). The NFRP NFRA will bring together established NF investigators (one Director and one Deputy Director) and early-career independent investigators (Scholars) and their Career Guides to develop successful, highly productive NF scientists and clinicians that will conduct research with the aim of lessening the clinical impact of NF1, NF2, and schwannomatosis. The NFRA is a multi-institutional interactive virtual academy platform designed to offer support to NFRA Scholars with the goal to advance innovative, high impact NF research through a collaborative and career development environment.The functioning NFRA will consist of Scholars and their Career Guides (mentors) from different institutions, and an Academy Director and Deputy Director (see Figure 1 below). The Academy Director and Deputy Director will catalyze the growth and professional development of the Scholars in collaboration with their Career Guides, assess the progress of the Scholars, and facilitate communication and collaboration among all Academy members. The Career Guide is not required to be at the same institution as the Scholar; however, if the (primary) Career Guide is from a different institution, a secondary Career Guide at the Scholars institution is needed. The NFRA will afford Scholars opportunities to operate in a collegial, highly dynamic, and cutting-edge center to move early-career investigators towards positions as leaders in NF conducting impactful research.During this first phase of the academy, the NFRP is offering the FY24 NFRALA funding opportunity to solicit applications for an Academy Director and Deputy Director to lead the NFRA. The Academy Director and Deputy Director (referred to as Academy Leadership) must be established NF researchers and can be at different institutions. The Academy Leadership must demonstrate a strong record of mentoring and training early-career independent investigators, a commitment to leadership, the ability to articulate methods toward research collaborations, and the ability to objectively assess the progress of all Scholars in the NFRA. An objective of the NFRA leadership team is to establish the Academy structure in its first year and in subsequent years, conduct oversight of this activity. Other objectives will include execution of research that will engage NFRA FY25 Scholars (including subsequent-year Scholars), develop tools for Scholars to enable success, and provide opportunities to broaden their knowledge in NF disorders. The leadership team will identify and offer opportunities to network with other NFRP FY25 Early Investigator Research Award recipients (and subsequent year awardees) and NFRP FY25 New Investigator Award Early-Stage Investigator (NIA ESI) Award recipients (and subsequent year awardees). In the second stage of the academy, the NFRP anticipates release of funding opportunities for the Scholars who will conduct their research under the guidance of the NFRA leadership team.

Science and Technology
Nonprofits
Provide technical assistance (TA) to support the Botswana Ministry of Health (MOH) implement policies and programs across the HIV clinical and prevention cascade under the Presidents Emergency Plan for AIDS Relief (PEPFAR)
$7,500,000
U.S. Department of Health & Human Services (Centers for Disease Control-GHC)
Federal

Application Deadline

Feb 19, 2025

Date Added

Jul 26, 2024

This funding opportunity provides financial support to various organizations to assist the Botswana Ministry of Health in implementing effective HIV prevention and treatment programs, particularly for underserved populations.

Health
State governments
Behavioral and Integrative Treatment Development Program (R01 Clinical Trial Optional)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 5, 2025

Date Added

Sep 25, 2024

This grant provides funding for researchers to develop and test innovative behavioral treatments for individuals struggling with drug and alcohol misuse, particularly focusing on improving treatment effectiveness and accessibility for diverse populations.

Education
State governments
Climate Smart and Disaster Ready
$30,000,000
Agency for International Development (Agency for International Development)
Federal

Application Deadline

Jan 31, 2025

Date Added

Dec 16, 2024

This funding opportunity provides financial support for organizations to implement innovative solutions that enhance resilience and disaster preparedness in vulnerable communities affected by climate change and natural disasters.

Disaster Prevention and Relief
Nonprofits