GrantExec

Grants for Small businesses - Federal

Explore 1,532 grant opportunities

F25AS00228 Candidate Species Conservation Fund
$500,000
U.S. Department of the Interior (Fish and Wildlife Service)
Federal

Application Deadline

Sep 30, 2025

Date Added

May 22, 2025

This funding opportunity supports conservation projects for at-risk species in the U.S. by providing financial assistance to a diverse range of applicants, including nonprofits, educational institutions, and government entities, to implement proactive measures that prevent species from needing federal protection.

Natural Resources
State governments
Laboratories to Optimize Digital Health (R01 Clinical Trial Required)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Jan 8, 2025

Date Added

Jan 6, 2023

This funding opportunity supports research partnerships between technology developers and academic researchers to optimize and evaluate digital mental health interventions, particularly for underserved populations.

Health
State governments
Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
$5,000,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Aug 11, 2025

Date Added

Jan 6, 2025

This funding opportunity supports research projects aimed at developing safe and effective medications for treating substance use disorders, particularly for substances like cocaine, methamphetamine, and cannabis, and is open to a wide range of eligible institutions and organizations.

Education
State governments
DoD Melanoma, Melanoma Academy Scholar Award
$1,540,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Oct 1, 2025

Date Added

May 27, 2025

This grant provides funding to early-career researchers focused on melanoma to support their independent research and professional development while fostering collaboration within a network of experts.

Science and Technology
Nonprofits
DOD Amyotrophic Lateral Sclerosis, Therapeutic Development Award
$2,000,000
U.S. Department of Defense (Dept. of the Army -- U.S.AMRAA)
Federal

Application Deadline

Aug 27, 2025

Date Added

May 27, 2025

This grant provides funding for research aimed at developing new therapies for amyotrophic lateral sclerosis (ALS), specifically targeting projects that have already shown promise in preclinical studies and emphasize the use of biomarkers for therapeutic development.

Science and Technology
Nonprofits
Medical Devices for Pediatric Population Affected by Substance Use and Addiction (R41 - Clinical Trials Optional)
$400,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Feb 26, 2025

Date Added

Nov 22, 2024

This funding opportunity provides financial support for small businesses to develop innovative medical devices specifically designed to help children and young adults affected by substance use and addiction.

Education
Small businesses
Transition to Aging Research for Predoctoral Students (F99/K00 Clinical Trial Not Allowed)
$450,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 18, 2024

Date Added

Apr 11, 2022

The National Institute on Aging is offering a grant for graduate students interested in aging-related research, providing funding and support for their doctoral dissertation projects and transition into postdoctoral positions in the field.

Health
Public and State controlled institutions of higher education
ROSES 2024: F.20 Mentorship and Opportunities in STEM with Academic Institutions for Community Success (MOSAICS) Seed Funding
$2,000,000
National Aeronautics & Space Administration (NASA Headquarters)
Federal

Application Deadline

Mar 28, 2025

Date Added

Jun 11, 2024

This funding opportunity provides financial support for faculty and students at under-resourced academic institutions to collaborate with NASA on research projects, fostering mentorship and skill development in STEM fields.

Science and Technology
Nonprofits
Lighting Prize (L-Prize)
$10,000,000
U.S. Department of Energy
Federal

Application Deadline

Aug 5, 2025

Date Added

Aug 19, 2024

This initiative provides up to $10 million in prizes to innovators developing advanced LED lighting solutions that improve energy efficiency, quality, and accessibility for commercial use.

Energy
Small businesses
Mechanistic links between diet, lipid metabolism, and tumor growth and progression (UH2 Clinical Trial Not Allowed)
$200,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 23, 2025

Date Added

Oct 31, 2024

This funding opportunity supports researchers at higher education institutions and nonprofits to explore how dietary fats influence cancer growth and progression through molecular mechanisms, with a focus on preclinical studies.

Education
State governments
Rural Northern Border Behavioral Health Workforce Program
$200,000
U.S. Department of Health and Human Services (Health Resources and Services Administration)
Federal

Application Deadline

Mar 3, 2025

Date Added

Jul 15, 2024

The purpose of this program is to strengthen the behavioral health workforce in rural Northern Border Regional Commission (NBRC) service areas through supporting the recruitment and retention of behavioral health care providers.

Health
Nonprofits
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)
$1,972,828
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 6, 2025

Date Added

Jun 7, 2025

This funding opportunity supports small U.S.-based businesses in developing and scaling innovative therapies using extracellular vesicles for regenerative medicine applications, such as tissue and organ repair.

Health
Small businesses
Pilot projects to enhance utility and usage of data sets from the Molecular Transducers of Physical Activity Consortium (MoTrPAC) (R03 Clinical Trials Not allowed)
$50,000
U.S. Department of Health and Human Services (National Institutes of Health)
Federal

Application Deadline

Dec 26, 2024

Date Added

Oct 24, 2024

Grant Title: Pilot projects to enhance utility and usage of data sets from the Molecular Transducers of Physical Activity Consortium (MoTrPAC) aims to fund small research projects that develop innovative methods to analyze and utilize MoTrPAC data, particularly focusing on how physical activity affects health, with a budget of up to $50,000 for one year.

Health
State governments
Gabriella Miller Kids First Training and Outreach Core (U24 Clinical Trials Not Allowed)
$800,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Oct 30, 2025

Date Added

May 15, 2025

This funding opportunity supports organizations in developing training and outreach initiatives to enhance the use of pediatric research data, focusing on childhood cancer and congenital anomalies.

Health
State governments
Ruth L. Kirschstein National Research Service Award (NRSA) Individual Fellowship for Students at Institutions with NIH-Funded Institutional Predoctoral Dual-Degree Training Programs (Parent F30)
Contact for amount
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Not specified

Date Added

Aug 16, 2023

This funding opportunity supports students enrolled in dual-degree medical and research training programs, helping them develop into independent physician-scientists through mentored research and clinical training.

Education
State governments
Infrastructure for Rebuilding America (INFRA)
$2,700,000,000
U.S. Department of Transportation
Federal

Application Deadline

May 6, 2024

Date Added

Apr 2, 2024

The INFRA program, part of the MPDG, allocates $2.7 billion towards competitive grants for significant multimodal freight and highway projects that aim to improve the safety, efficiency, and reliability of freight and people movement across rural and urban areas. It focuses on projects that enhance economic benefits, reduce congestion, increase resiliency, and improve critical freight movements. The program encourages applications that address supply chain bottlenecks and are of national or regional significance. The application deadline is May 6, 2024.

Transportation
State governments
Child Welfare and Domestic Violence Agency Collaborations to Support Families
$250,000
U.S. Department of Health & Human Services (Administration for Children and Families - ACYF/CB)
Federal

Application Deadline

Mar 21, 2025

Date Added

Jul 30, 2024

This funding opportunity provides financial support to state and tribal agencies, community organizations, and collaborations focused on improving safety and well-being for families affected by domestic violence and child welfare issues.

Income Security and Social Services
State governments
Onaa 2024 Natep
$240,000
Small Business Administration
Federal

Application Deadline

Aug 15, 2024

Date Added

Jul 31, 2024

The Office of Native American Affairs (ONAA) mission is to ensure that American Indian, Alaska Natives and Native Hawaiians (referred to collectively as Native American) seeking to create, develop and expand small businesses have full access to the business development and expansion tools available through the Agencyโ€™s entrepreneurial development, lending and procurement programs. ONAAโ€™s overarching goal is to promote and support American Indians, Alaska Natives and Native Hawaiian entrepreneurs. In recent years, ONAA has successfully sponsored and managed nation- wide contractor-led workshops and roundtables, co-sponsored agreements, interagency agreements, and tribal consultations; developed and distributed promotional materials; and attended and participated in national and regional economic development conferences as subject matter experts for these groups. The focus of this pilot program initiative is to award a grant to a Native American serving business to carry out projects that support developing exports by eligible Native small businesses. The objective of NATEP is to increase (1) the number of Native small businesses that export, (2) the dollar value of exports, and (3) the number of Native small businesses exploring significant new trade opportunities. Such empowerment will serve to maximize economic impact and improve quality of life for the targeted underserved communities. Section 7(j) of the Small Business Act authorizes the U.S. Small Business Administration to provide management and technical assistance to eligible individuals and businesses. To be eligible for 7(j) services, a client must be: a socially and economically disadvantaged individual whose firm is a participant in the 8(a) Business Development Program; a business that is eligible to receive 8(a) contracts; or a business which qualifies as small under 13 CFR subpart 121 โ€“ Small Business size Regulations, and which is located in an urban or rural area with a high proportion of unemployed or low-income individuals, or which is owned by low-income individuals. The term โ€œhigh proportion of unemployedโ€ means the urban or rural countyโ€™s unemployment rate is not less than 140 percent of average unemployment rate for the United States or for the State in which such county is located, whichever is less, based on the most recent data available in the annual Local Area Unemployment Statistics report from the U.S. Department of Labor, Bureau of Labor Statistics. The term โ€œlow- income individualโ€ means an individual whose familyโ€™s taxable income for the preceding year did not exceed 150 percent of the poverty level amount established by the Bureau of Census, U.S. Department of Commerce, for determining poverty status.

Business and Commerce
Native American tribal organizations
Notice of Intent to Publish a Funding Opportunity for Maximizing the Scientific Value of Data Generated by the Environmental Influences on Child Health Outcomes (ECHO) Program: Ruth L. Kirschstein NRSA Individual Postdoctoral Fellowship (F32)
$75,000
U.S. Department of Health & Human Services (National Institutes of Health)
Federal

Application Deadline

Mar 17, 2025

Date Added

Nov 26, 2024

This funding opportunity supports postdoctoral researchers conducting studies on the impact of early environmental factors on child health using a large national dataset.

Health
State governments
HPAI Poultry Innovation Grand Challenge
$2,000,000
U.S. Department of Agriculture (Animal and Plant Health Inspection Service)
Federal

Application Deadline

May 19, 2025

Date Added

May 14, 2025

This funding opportunity provides up to $100 million to various organizations for innovative projects aimed at developing vaccines, therapeutics, and research strategies to combat highly pathogenic avian influenza in the U.S. poultry industry.

Agriculture
For profit organizations other than small businesses