Federal Health Grants

This funding opportunity supports organizations in developing training and outreach initiatives to enhance the use of pediatric research data, focusing on childhood cancer and congenital anomalies.

This funding opportunity supports students enrolled in dual-degree medical and research training programs, helping them develop into independent physician-scientists through mentored research and clinical training.

This funding opportunity supports pain research projects at eligible educational institutions, promoting collaboration between students and experienced researchers to advance understanding and management of pain while addressing the opioid crisis.

This grant provides funding for research projects focused on improving health outcomes through lifestyle medicine for individuals affected by the 9/11 attacks, including responders and survivors receiving care under the WTC Health Program.

The "Blueprint Medtech: Small Business Translator" grant aims to support small businesses in developing and testing therapeutic and diagnostic devices for nervous or neuromuscular disorders, with funding and expert assistance provided for activities such as clinical studies, safety testing, and design validation, ultimately leading to FDA or IRB approval.

This is a non-competitive funding opportunity intended to fund a single award. NCATS is announcing its intent to issue a single source cooperative agreement to Cincinnati Childrens Hospital Medical Center (CCHMC) to support the Data Management and Coordinating Center. The Rare Diseases Clinical Research Network (RDCRN) is intended to advance and improve diagnosis, management, and treatment of numerous, diverse rare diseases through highly collaborative, multi-site, patient-centric, translational, and clinical research with an emphasis on early and timely identification of individuals with rare diseases and clinical trial readiness. The DMCC facilitates and supports the activities of each individual Rare Diseases Clinical Research Consortium (RDCRC) along with trans-network activities that broadly facilitate the advancement of rare disease research via four avenues: administrative support, data management support, clinical research support and patient engagement, and broad dissemination of information. The RDCRCs will continue conducting research conducted under a separate NOFO.

The REDI: NIA Entrepreneurship Enhancement Award (R25) is a grant aimed at providing entrepreneurial training to graduate students, postdocs, and early career scientists in fields related to aging and Alzheimer's disease research, to prepare them for diverse career paths.

This funding opportunity supports promising predoctoral students from diverse backgrounds to conduct research in translational studies related to Alzheimer's disease and related dementias, fostering skills essential for advancing this critical field.

Notice of Funding Opportunity Description Background Although vaccines are among the most effective approaches to control viral diseases, developing a prophylactic or therapeutic HIV vaccine has proven elusive. There are no licensed vaccines for HIV. Strategies for induction of HIV broadly neutralizing antibodies will likely require repeated exposures over long periods, including immunization with distinct antigens in sequential order. Such immunization strategies will require development of technologies for controlled vaccine release. Recent advances in materials-based science, controlled release technologies, delivery systems, and immunology provide opportunities to enhance the quality, potency and durability of vaccine-induced T cell and antibody responses to HIV-1. Materials-based approaches can be engineered to improve the stability, spatiotemporal release, and presentation of multiple vaccine components; for example, by controlling the time frame and dose of vaccine delivery over days to weeks. Recent studies have shown that a slow-release vaccine is superior to bolus administration at inducing breadth, potency, and durability of antibody responses to HIV antigens by prolonging antigen exposure in the germinal centers, thereby enhancing the maturation of B cells and generating stronger humoral immune responses. Further research is needed to elucidate the mechanisms underlying the immunological improvements observed with slow-release vaccine delivery and to translate such concepts into clinical application. It will be crucial to determine how the duration of exposure to vaccine components impacts immune cell biology, and how to calibrate vaccine release to improve responses while avoiding immune exhaustion and over-activation. Advancing safe, effective, and well-tolerated controlled release vaccines is an unmet need that may enhance vaccine effectiveness and practicality, leading to better adherence to complex regimens, fewer adverse reactions, and cost savings. Finally, iterative behavioral studies during product development to determine vaccine/provider product expectation/preferences are critical to facilitate product uptake and use.

This funding opportunity supports postdoctoral researchers conducting studies on the impact of early environmental factors on child health using a large national dataset.

This funding opportunity supports primary care centers in implementing genomic screening for common genetic conditions to improve disease prevention and care, particularly in underrepresented communities.

This funding opportunity supports research initiatives focused on non-communicable diseases related to HIV at institutions in low- and middle-income countries, encouraging innovative projects and collaborations to improve health outcomes for people living with HIV.

This funding opportunity provides financial support to education and health agencies for developing and implementing sustainable school-based strategies to prevent HIV and STDs among middle and high school students in the United States.

The United States Agency for International Development (USAID) is seeking applications for a cooperative agreement from qualified entities to implement the Kenya Digital Health Ecosystem Activity. Eligibility for this award is restricted to local organizations in Kenya. However, USAID strongly encourages these organizations to collaborate with at least one international entity as a subrecipient and apply as a consortium. See details in section C. USAID intends to make an award to the applicant(s) who best meets the objectives of this funding opportunity based on the merit review criteria described in this NOFO, and subject to a risk assessment. Eligible parties interested in submitting an application are encouraged to read this NOFO thoroughly to understand the type of program sought, application submission requirements, and selection process. This notice of funding opportunity (NOFO) will follow a 3-phase process as described below: ● Phase 1: Submission of concept papers ● Phase 2: Participation in an oral presentation by the selected applicant(s) ● Phase 3: Submission of full application by the Apparently Successful Applicant (ASA) Phase 1 is the submission of a Concept Paper that will be reviewed for responsiveness to the purposes of the NOFO and be evaluated in accordance with the merit review criteria provided in Section E of this NOFO. The highest rated applicants will advance to Phase 2, where they will present their proposed plan orally to the Merit Review Committee. The oral presentation will also be evaluated in accordance with the merit review criteria provided in Section E of this NOFO. From Phase 2, an Apparently Successful Applicant will be identified and invited to Phase 3, and submit a full application, which will be evaluated in accordance with the merit review criteria provided in section E of this NOFO.

This funding opportunity provides financial support for research projects that address the information and practice needs of caregivers and professionals working with children who experience delays in language development, particularly focusing on diverse communities.

This funding opportunity provides financial support to organizations working in Malawi to improve health information systems and enhance care for individuals affected by HIV/AIDS.

This Notice of Funding Opportunity (NOFO) seeks to foster new multi-disciplinary teams to address how HIV Comorbidities and co-infections within the missions of NIDDK and NIAID interact with viral reservoirs, potentially confounding cure strategies aimed at either sustained viral suppression or elimination from the body. These teams will mechanistically interrogate the impact of inflammation, metabolic perturbations, or other pathophysiological processes associated with these comorbidities or co-infections on reservoir dynamics, and/or the interplay of these conditions and co-infections on HIV reservoir biology in ways that are likely to interact with potential cure strategies.

This funding opportunity provides financial support to organizations working in Lesotho to strengthen health systems and improve services for HIV and TB prevention, treatment, and care, with a focus on achieving health equity and sustainability.

This funding opportunity is designed to support research centers that focus on improving the diagnosis, treatment, and prevention of intellectual and developmental disabilities through collaborative and interdisciplinary research efforts.

The purpose of this program is to prepare Tribes, Tribal organizations, and Urban Indian Health Programs for conducting Public Health Department functions, services and activities, and further develop and improve their Public Health management capabilities. The Indian Health Service (IHS) is offering competitive awards to assist applicants in expanding Essential Public Health Services (EPHS) implementation within established tribal public health programs. The 10 EPHS include: 1. Assess and monitor population health status, factors that influence health, and community needs and assets.2. Investigate, diagnose, and address health problems and hazards affecting the population.3. Communicate effectively to inform and educate people about health, factors that influence it, and how to improve it.4. Strengthen, support, and mobilize communities and partnerships to improve health.5. Create, champion, and implement policies, plans, and laws that impact health.6. Use legal and regulatory actions designed to improve and protect the publics health.7. Contribute to an effective system that enables equitable access to the individual services and care needed to be healthy.8. Build and support a diverse and skilled public health workforce.9. Improve and innovate public health functions through ongoing evaluation, research, and continuous quality improvement.10. Build and maintain a strong organizational infrastructure for public health.