Federal Health Grants

This funding opportunity supports the establishment of a Coordinating Center to enhance diversity in the aging research workforce through targeted undergraduate education initiatives.

This funding opportunity supports collaborative research projects aimed at addressing brain and nervous system disorders in low- and middle-income countries, focusing on building sustainable research capacity and improving neuro-health outcomes.

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Funding Opportunity Announcement (FOA) encourages Exploratory/Developmental Phased Innovation (R61/R33) grant applications to support development of clinical trials to treat critical and co-occurring health conditions in individuals with Down syndrome. The proposed research aims should be milestone-driven. The total project period for an application submitted in response to this FOA may not exceed five years. This FOA provides support for up to two years (R61 phase) for preliminary/developmental/planning studies, followed by possible transition to clinical trial support (R33) of up to three years, although the total duration of the award may not exceed five years. This FOA requires measurable R61 milestones.

Every year more than 795,000 people in the United States have a stroke. On average, thats 1 person every 40 seconds. On average, 1 American dies from a stroke every 3 minutes and 14 seconds. Approximately 9.4 million American adults 20 years of age self-report having had a stroke. These data are disturbing, more so as 80% of strokes are preventable.Prevention begins with implementing equity-focused systems and interventions that assist populations at the highest risk in detecting and managing cardiovascular disease (CVD) and mitigating systemic social conditions that contribute to the increased prevalence of CVD. Roughly 1 in 10 (9.9% 28.6 million) adults in the US have at least 1 type of CVD, including coronary heart disease, heart failure, or stroke. This number excludes hypertension, a risk factor for and cause of CVD but not a type of CVD. However, hypertension or high blood pressure is a critical risk factor for stroke. An estimated 120 million American adults (48.1%) have it, most (3 in 4) dont have it controlled, and 1 in 5 adults is unaware they have hypertension. High blood cholesterol, smoking, obesity, and diabetes also contribute to stroke risk.Heart disease, stroke, and their modifiable risk factors are experienced disproportionately throughout the US population based on race and ethnicity, social factors, and geography. Non-Hispanic Black Americans have a higher prevalence and highest death rate from stroke than any other racial group. While non-Hispanic Blacks had the highest age-adjusted stroke death among all races and ethnicities (59.6 per 100,000) in 2021, the age-adjusted stroke death rate for individuals across the board increased from 38.8 per 100,000 in 2020 to 41.1 per 100,000 in 2021. Stroke deaths also increased in southern states, where populations at a higher risk, specifically communities of color, exist. These numbers highlight the critical need to improve access to quality care for those at the highest risk of stroke and for stroke patients.In 2001, Congress provided funding to CDC to establish the Paul Coverdell National Acute Stroke Registry, named after the late US Senator Paul Coverdell of Georgia, who suffered a fatal stroke in 2000 while serving in Congress. In 2012, as the program expanded, the name changed to the Paul Coverdell National Acute Stroke Program. The aim has been to support the implementation of comprehensive stroke systems for individuals at the highest risk of stroke and for stroke patients across the continuum of care from the onset of stroke symptoms through rehabilitation and recovery.This new iteration of Coverdell supports state stroke systems in partnerships with learning collaboratives or coalitions to improve state-level stroke care for those at the highest risk. Recipients will be required to execute a dual approach to addressing stroke in the coordinated systems of care and the implementation of prevention activities in community settings. Recipients will continue their collection and analysis of in-hospital stroke data for those who have experienced a stroke while adding a deep focus on understanding and mitigating the stroke risks among individuals in their communities, also ensuring post-discharge follow-up in either rehabilitation facilities or other community-supportive recovery services.This NOFO requires Coverdell recipients to integrate their work with CDCs other funded programs in states where they exist to mitigate systemic inequities and reduce the prevalence of CVD and hypertension so that another person doesnt die from a stroke every 3 minutes and 14 seconds.

This funding opportunity provides $4 million to organizations that can strengthen public health systems and enhance health security in Mali, particularly in challenging and insecure areas.

The purpose of the NIH Independent Scientist Award (K02) is to foster the development of outstanding scientists and enable them to expand their potential to make significant contributions to their field of research. The K02 award provides three to five years of salary support and "protected time" for newly independent scientists who can demonstrate the need for a period of intensive research focus as a means of enhancing their research careers. Each independent scientist career award program must be tailored to meet the individual needs of the candidate. This Parent Funding Opportunity Announcement is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should be submitted under this FOA include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Applicants not planning an independent clinical trial or basic experimental study with humans, or proposing to gain research experience in a clinical trial or basic experimental study with humans led by another investigator, must apply to the 'Independent Clinical Trial Not Allowed' companion FOA. The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.

This funding opportunity provides financial support to organizations that improve mental health services for children, youth, and families, focusing on collaboration, training, and engagement in the systems of care approach.

This grant provides funding to public health organizations and healthcare providers in the United States to improve prevention, diagnosis, and management of parasitic infections, particularly focusing on Chagas disease, soil-transmitted helminths, and other significant domestic parasitic diseases.

This program provides funding to support tree planting and urban forestry projects in disadvantaged communities across Georgia, promoting long-term environmental benefits.

The purpose of this Notice of Funding Opportunity (NOFO) is to solicit research designed to capacitate, transform, and scale the delivery of HIV testing, prevention, and care services through pharmacists and pharmacies in US and/or global settings. This includes theadvancement of training curricula to enable pharmacy students, pharmacists, pharmacies, and pharmacy systems to deliver the spectrum of needed HIV services with ease, equity, and effectiveness. This NOFO uses the R21 grant mechanism, while RFA-MH-25-185 uses the R01 mechanism. Projects that lack preliminary data or that propose to pilot a novel intervention may be most appropriate for the R21 mechanism. Applications with preliminary data and those proposing large-scale clinical trials or longitudinal analyses should consider using the R01 mechanism.

The purpose of this Planning Cooperative Agreement is to provide resources to Tribes interested in entering the Tribal Self-Governance Program (TSGP) and to existing Self Governance Tribes interested in assuming new or expanded PSFAs. Title V of the Indian Self-Determination and Education Assistance Act (ISDEAA) requires a Tribe or Tribal organization (T/TO) to complete a planning phase to the satisfaction of the Tribe. The planning phase must include legal and budgetary research and internal Tribal government planning and organizational preparation relating to the administration of health care programs. The planning phase is critical to negotiations and helps Tribes make informed decisions about which Programs, Services, Functions, and Activities (PSFAs to assume and what organizational changes or modifications are necessary to successfully support those PSFAs. A thorough planning phase improves timeliness and efficient negotiations and ensures that the Tribe is fully prepared to assume the transfer of IHS PSFAs to the Tribal health program. A Planning Cooperative Agreement is not a prerequisite to enter the TSGP and a Tribe may use other resources to meet the planning requirement. Tribes that receive Planning Cooperative Agreements are not obligated to participate in the TSGP and may choose to delay or decline participation based on the outcome of their planning activities. This also applies to existing Self Governance Tribes exploring the option to expand their current PSFAs or assume additional PSFAs.

This funding opportunity provides financial support for research projects that explore how policies on tobacco, alcohol, and cannabis use affect health disparities in underserved communities, with a focus on cancer prevention and community collaboration.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications for research training programs to strengthen the scientific capacity of institutions in low- and middle-income countries (LMICs) to conduct HIV research relevant to the evolving HIV epidemic in their country. This FOA can support training for conducting research in a broad range of HIV research areas across HIV prevention, treatment, care, and quality of life continuum. This includes basic, epidemiologic, clinical, behavioral and social sciences, community-based, implementation, operations, health services, and health systems research. Cross-disciplinary research as well as HIV associated comorbidities and coinfections affecting the HIV epidemic will be supported under this FOA. An application should focus the proposed training program to strengthen research capacity in a defined high priority HIV scientific area aligned with NIH HIV/AIDS research priorities (NOT-OD-20-018) at a specific LMIC institution and collaborating LMIC partner institutions.

This funding opportunity provides financial support to a variety of organizations to improve coordinated care and research for individuals affected by a rare genetic disorder that causes abnormal blood vessel formation.

This funding opportunity supports small-scale research projects at undergraduate-focused institutions to enhance research capabilities and engage students in biomedical research.

The Childrens Hospitals Graduate Medical Education (CHGME) Payment Program compensates for the disparity in federal graduate medical education funding for freestanding childrens teaching hospitals as compared to other types of teaching hospitals who primarily serve adults and receive federal graduate medical education funding through the Medicare Program. The CHGME Payment Program supports graduate medical education in freestanding childrens teaching hospitals to train physicians across multiple specialties and to provide quality care to vulnerable and underserved children.

The five-year USAID National Family Planning and Adolescent Reproductive Health (FP/ARH) Activity (2024-2029) aims to improve family planning and adolescent reproductive health in the Philippines. It is a key component of the USAID Universal Health Care Project (UHCP) with the goal of improving health outcomes of underserved Filipinos. The FP/ARH Activity will help advance the Philippine governments efforts under the Universal Health Care law to improve the delivery of quality preventive, promotive care at the primary health care level. The Activity will contribute to achieving the Philippine governments health goals as follows: Increase the demand satisfied with modern FP methods among all women of reproductive age from 42 percent in 2022 to 75 percent by 2030; Reduce the adolescent birth rate from 25 per 1,000 girls (age 15-19) in 2022 to 12 per 1,000 girls by 2030; and Reduce the maternal mortality ratio from 144 per 100,000 live births in 2020 to less than 70 per 100,000 live births by 2030

The purpose of the The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative Fellows (F32) program is to enhance the research training of promising postdoctorates, early in their postdoctoral training period, who have the potential to become productive investigators in research areas that will advance the goals of the BRAIN Initiative. Applications are encouraged in any research area that is aligned with the BRAIN Initiative, including neuroethics. Applicants are expected to propose research training in an area that clearly complements their predoctoral research. Formal training in analytical tools appropriate for the proposed research is expected to be an integral component of the research training plan. In order to maximize the training potential of the F32 award, this program encourages applications from individuals who have not yet completed their terminal doctoral degree and who expect to do so within 12 months of the application due date. On the application due date, candidates may not have completed more than 12 months of postdoctoral training.

The "Ending the Epidemic: New Models of Integrated HIV/AIDS, Addiction, and Primary Care Services" grant aims to fund research for developing and testing new care models that effectively combine HIV, addiction, and primary care services to improve health outcomes for individuals at high risk for or living with HIV, Hepatitis, and substance use disorders in the US.

This funding opportunity supports researchers in studying and characterizing genetically modified mice that exhibit early life lethality or reduced viability, contributing to our understanding of gene function and its implications for human health.