Federal Health Grants

This Funding Opportunity Announcement (FOA) encourages pilot and preliminary research in preparation for larger-scale services research effectiveness trials. Relevant trials may test a wide range of approaches, including interventions, practices, and policies designed to optimize access to, and the quality, effectiveness, affordability and utilization of drug, tobacco, or alcohol use disorder treatments and related services, as well as services for comorbid medical and mental disorder conditions. Relevant approaches may include both those that are novel, and those that are commonly used in practice but lack an evidence base. This FOA provides resources for assessing the feasibility, acceptability, and utility of these approaches, in addition to usual trial preparation activities.

This funding opportunity supports research projects that utilize existing cancer epidemiology cohort data to investigate important questions about cancer prevention, treatment, and survivorship, particularly for underserved populations and rare cancers.

The National Institute of Diabetes and Digestive and Kidney Disorders (NIDDK) intends to promote a new initiative by publishing a Notice of Funding Opportunity (NOFO) to solicit applications for the TrialNet Coordinating Center (TNCC). The TrialNet network identifies people with type 1 diabetes (T1D) at stages before and after onset of clinical symptoms and enrolls them in trials and studies aimed at prevention of progression to clinical disease and preservation of insulin production. The TNCC participates in ongoing studies and intervention trials as well as the design and conduct of new studies and intervention trials. The TNCC will: (1) support a wide range of research projects in varying stages of development, implementation and completion, and (2) provide data and sample management, including standardized acquisition, quality control, dissemination and public accessibility. The TNCC will be responsible for network administration and operations, including the evaluation, selection, and funding (through subcontracts) of Clinical Centers and central support units (such as laboratories) necessary for the conduct of TrialNets clinical studies. The TNCC PD/PI will be a voting member of the TrialNet Executive and Steering Committees, contributing to network leadership. This NOFO requires a Plan for Enhancing Diverse Perspectives (PEDP), which will be assessed as part of the scientific and technical peer review evaluation. Applications that fail to include a PEDP will be considered incomplete and will be withdrawn. Applicants are strongly encouraged to read the NOFO instructions carefully and view the available PEDP guidance material. This Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. The NOFO is expected to be published in Spring 2024 with an expected application due date in Summer 2024. This NOFO will utilize the U01 activity code. Details of the planned NOFO are provided below.

RFI Number: 7200AA24RFI00017Issuance Date: April 22, 2024Closing Date: May 20, 2024 5:00pm EDTSubject: Accelerating HIV Vaccine Research and Development in Low- and Middle-Income Countries (LMIC)To All Interested Respondents/Parties:The United States Agency for International Development (USAID) Bureau for Global Health (GH) is publishing this Request for Information (RFI) to obtain information and input that will be used to help make planning decisions. It may inform the design of future activities related to accelerating HIV vaccine research and development in low- and middle-income countries.This RFI is issued solely to collect expert inputs for information-gathering and planning purposes. This RFI does not constitute a Notice of Funding Opportunity (NOFO) or a Request for Proposals (RFP).Please also note the following:(a) responding to this Notice will not give any advantage to any organization or individual for any subsequent competition;(b) proprietary information should not be sent;(c) responses are not offers/applications and cannot be accepted by the U.S. Government to form a binding contract/award;(d) responses to this RFI are strictly voluntary, and USAID will not pay respondents for information provided in response to this RFI;(e) USAID reserves the right to, or not to, incorporate any/some/none of the comments received from RFI into subsequent solicitations or design documents and(f) applications or resumes will be discarded and should therefore not be included in your response.USAID posts its competitive business opportunities on www.sam.gov and www.grants.gov. This RFI does not restrict the Governments approach to a future solicitation or NOFO. It is the potential responders responsibility to monitor the site for the release of any further information.Questions regarding this announcement will not be accepted or answered. Not responding to this request does not preclude participation in any future solicitation, if any is issued. No basis for claims against the U.S. Government shall arise as a result of a response to this request for information or from the U.S. Governments use of such information.Submission Instructions:Only electronic submissions will be accepted. Responses to this RFI must be written in English.Respondents will only receive an electronic confirmation acknowledging receipt of their response; theywill not receive individualized feedback on any suggestions.USAID is requesting the public to submit short submissions outlining recommendations or otherinformation pertinent to the questions noted below. Responses should note the question numberaddressed and clearly relate back to the questions listed below, but responses do not need to addressevery question listed. All responses should provide sufficient detail and justification explaining why acertain recommendation is offered. Please also provide your name, title, organization, and contactinformation in the response.All submissions must adhere to the following format to ensure an efficient review: Must be written in English, size 11 Calibri font, not to exceed 20 pages total. The graphics subtextmay use a smaller font size. Submission file should be in PDF or Microsoft Word format. Submission file should be saved as ;lt;Entitys name;gt; Response to RFI 7200AA24RFI00017. The subject line for the submission email subject line must include Response to USAID/GHs RFI- Accelerating HIV Vaccine Research and Development in LMIC Must be submitted to Ms. Simone Cho at [email protected] with a copy to Mr. Elton Fortson [email protected] by the closing date and time noted at the beginning of this letter.Thank you for your interest in responding to this RFI. To learn more about partnering with USAID, pleasevisit www.work with usaid.gov.

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This funding opportunity provides up to $1 million to a wide range of organizations to develop a centralized resource for exploring and analyzing single-cell genomics data from the human brain, enhancing research on brain health and disease.

Through this Funding Opportunity Announcement (FOA), the National Cancer Institute (NCI) invites applications for support of investigator-initiated studies addressing mechanisms by which bariatric surgery impacts cancer risk, and seeks to draw in talented scientists who study bariatric surgery to investigate its effects on cancer, rather than shorter term outcomes such as weight loss and diabetes. The goal of this FOA is to support proof of concept studies for feasibility and exploratory development. Feasibility must not have already been developed in the literature or with preliminary data. While unpublished data are not permitted, references and data from widely available preprints that have a Digital Object Identifier (DOI) are acceptable. Investigators who have generated unpublished preliminary data should submit a proposal to companion R01.

This funding opportunity provides financial support to federally recognized Indian tribes and Alaska Native villages for projects that improve housing, infrastructure, and economic development, primarily benefiting low- and moderate-income individuals.

This funding opportunity supports researchers with a strong background in promoting diversity, equity, inclusion, and accessibility in biomedical fields, enabling them to conduct scientific research while advancing DEIA initiatives within the academic and scientific communities.

The purpose of this Funding Opportunity Announcement (FOA) is to encourage grant applications for investigator-initiated efficacy clinical trials to the National Institute of Neurological Disorders and Stroke (NINDS). The trials must address questions within the mission and research interests of the NINDS and may evaluate drugs, biologics, and devices, as well as surgical, behavioral and rehabilitation therapies. Information about the mission and research interests of the NINDS can be found at the NINDS website (http://www.ninds.nih.gov/)

This grant provides financial support for early-career researchers from diverse backgrounds to establish independent cancer research careers, particularly those planning to lead clinical trials.

This funding opportunity is designed to support U.S. institutions that grant doctoral degrees in health-related fields and are current recipients of RCMI awards, enabling them to enhance their research capabilities and address health disparities.

The purpose of this program is to increase the amount of high quality, impartial, policy-relevant research to assist providers and decision/policy-makers at the federal, state and local levels to better understand problems faced by rural communities and provide information that will be applied in ways that improve health care in rural areas. This notice announces the opportunity to apply for funding under the Rural Health Research Center (RHRC) Program. The purpose of this cooperative agreement is to support high-quality, impartial, policy-relevant research to assist health care providers and decision/policy-makers at the federal, state and local levels in better understanding the challenges faced by rural communities and in designing policies to improve health care access and population health. RHRC recipients will conduct policy-oriented health services research, update trend analyses and existing research, and conduct necessary literature reviews on rural issues and synthesize the issues into publically available policy briefs designed to be easily understood by a non-technical audience. In addition to primary and secondary research, the applicant must be willing and able to conduct literature syntheses and update existing research to produce timely and relevant information. The ratio of original research to other needed projects will be reviewed by the Federal Office of Rural Health Policy (FORHP) and the final ratio will be negotiated between the recipients and the Federal Office of Rural Health Policy. The four-year RHRC Program awards are designed to support research centers with specific rural health research areas of concentration. The topic(s) of concentration must be policy-relevant and of enduring interest and importance to rural providers, rural stakeholders, policy makers and/or rural communities. A goal of the RHRC Program is to produce new information, through the research activities supported by this cooperative agreement, which can be applied in ways that directly inform improvements in access to health care and population health for rural America. This cooperative agreement program will support health services research projects and will exclude clinical/biomedical research and the expenditure of funds for delivery of health care services. The Agency for Healthcare Research and Quality (AHRQ) defines the term “health services research” as research that examines “how people get access to health care, how much care costs, and what happens to patients as a result of this care.” The main goals of health services research are to “identify the most effective ways to organize, manage, finance, and deliver high quality care; reduce medical errors, and improve patient safety.”1

This Funding Opportunity Announcement (FOA) is intended to provide an avenue for basic scientists, clinicians and clinical scientists to jointly initiate and conduct translational research projects which translate basic research findings into clinical tools for better human health. The scope of this FOA includes a range of activities to encourage translation of basic research findings which will impact the diagnosis, treatment and prevention of communication disorders. Connection to the clinical condition must be clearly established and the outcomes of the grant must have practical clinical impact.

The grant titled "The NINDS Human Cell and Data Repository" aims to support the maintenance and development of a repository for fibroblast and induced pluripotent stem cell lines, which will be distributed to researchers for advancing research in neurological disorders.

This grant provides funding to early career researchers proposing innovative studies on the genetics or epigenetics of substance use disorders, aiming to foster new insights and advancements in addiction research.

This funding opportunity announcement (FOA) invites applications for the Clinical and Translational Science Award (CTSA) Program hubs that will be part of a national, collaborative consortium focused on bringing more treatments to more patients more quickly through advancing clinical and translational science (CTS) by (1) developing, demonstrating, and disseminating scientific and operational innovations that improve the efficiency and effectiveness of clinical translation from identification to first-in-human studies to medical practice implementation to community health dissemination; (2) promoting partnerships and collaborations to facilitate and accelerate translational research projects locally, regionally, and nationally; (3) creating, providing, and disseminating innovative research programs and partnerships across institutions and communities to address health disparities and deliver the benefits of translational science to all; (4) creating and implementing scientific and operational innovations that increase the quality, safety, efficiency, effectiveness, and informativeness of clinical research; (5) providing a national resource for the rapid response to urgent public health needs; and (6) creating, providing, and disseminating CTS training for clinical research professionals of all disciplines on the research team. Along with this solicitation for the UM1 CTSA hub application, NCATS has published a separate, companion FOA that solicits applications for a required K12 Clinical Scientist Institutional Career Development Program Award (PAR-TR-22-career); both a UM1 hub application and the required K12 application must be submitted. If there is no companion K12 application submitted, the UM1 hub application will not be reviewed. However, if the UM1 application is funded and the companion K12 application is not funded, a resubmitted K12 application will be accepted. Additional companion FOAs solicit applications for optional training, career, and research ed

This funding opportunity provides financial support to various organizations, including governments and nonprofits, to raise awareness and improve understanding of Alpha-gal Syndrome across the United States, particularly in underserved areas.

This funding opportunity supports organizations in the southern United States to create integrated care models that improve HIV treatment and essential support services for women living with HIV.

This program provides funding to innovators developing non-invasive tear-based diagnostic technologies for continuous health monitoring and personalized treatment, initially targeting Dry Eye Disease.