State Income Security and Social Services Grants

The Golden State Social Opportunities Program (GSSOP) makes awards to eligible applicants currently enrolled in a graduate program from a University of California or California State University campus or a nonprofit independent institution of higher education that prepares them to become a Licensed Clinical Social Worker, Licensed Marriage and Family Therapist, Licensed Professional Clinical Counselor, or a Licensed Clinical Psychology (PhD or PsyD) for a scholarship of up to $25,000 per year for a total of up to $50,000 in exchange for a 24-month service obligation practicing and providing direct patient care in a community-based organization.

The Behavioral Health Scholarship Program (BHSP) makes awards to eligible applicants currently accepted or enrolled in an accredited academic or certificate program that prepares them to become one of the eligible professionals under this program for a scholarship of up to $25,000 in exchange for a 12-month service obligation practicing and providing direct patient care in an underserved community in California.

This is a competitive renewal, supporting a single Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Collaborative Action Center (CAP:CAC). • A competitive renewal application will address the expansion of administrative services, resources, and support to funded hepatocellular carcinoma research projects along with strong justification for the continuation of the FY19.2 CAP:CAC award. • Applicants may request a maximum of $3,000,000 in total costs for a period of 5 years. • Multi-Principal Investigators (MIs) are allowed under this Request for Applications (RFA). See the Information for Applicants (IFA) document for definition and eligibility of MIs. • See application limitations for Principal Investigators (PIs)/MIs, regardless of whether the MI is from the prime institution or a subcontracted institution. • Note that CPRIT does not allow the use of the term Co-PI. • Minimum effort for the PI and/or MIs throughout the project period is required. • FY25 salary cap is $225,000 per year. • Competitive renewals are not subject to preliminary evaluation. Renewal applications move directly to the full peer review phase.

The Vermont Agency of Agriculture has entered into a cooperative agreement with the US Department of Agriculture (USDA) and the Agricultural Marketing Service (AMS) to administer the Resilient Food System Infrastructure (RFSI) grant program in Vermont. Donor Name: Vermont Agency of Agriculture Food & Markets (VAAFM) State: Vermont County: All Counties Type of Grant: Grant Deadline:  06/05/2024 Size of the Grant: $100,000 to $500,000 Grant Duration: 3 Years Details: The program aims to: Promote development of Vermont value-added products; Support initiatives that provide fair prices, fair wages, and new and safe job opportunities that keep profits in rural communities; Increase and diversify processing capacity across the state, with an emphasis on underserved communities; Improve the aggregation, processing, manufacturing, storing, transporting, wholesaling, and distribution of Vermont food products for local and regional markets; Target gaps and opportunities in pandemic assistance and existing USDA grant programs that support the agricultural supply chain. Funding will be focused on projects that: Improve job quality through increased wages, benefits, and/or worker safety and well being; Focus on small and medium-sized enterprises that expand services and product offerings for consumers and producers (with an emphasis on value-added products); Demonstrate local support for the project; Are submitted by cooperatives, farmer, and worker-owned enterprises. Funding Information Approximately $2,000,000 will be available for infrastructure projects. Grants can range from $100,000 – $500,000 and will run from fall 2024 through February 2027.  Eligibility Criteria Eligible applicants must be domestically owned, physically located in Vermont, and registered in Vermont with the Vermont Secretary of State. Sole proprietors using a business name other than their own name must have their assumed business name (formerly known as a trade name) registered with the Vermont Secretary of State. Eligible entities can include: Agricultural producers or processors, or groups of agricultural producers and processors operating middle-of-the-supply-chain activities such as processing, aggregation, distribution of targeted agricultural products. Nonprofit organizations operating middle-of-the-supply-chain activities such as processing, aggregation, distribution of targeted agricultural products. Local government entities operating middle-of-the-supply-chain activities such as processing, aggregation, distribution of targeted agricultural products. Institutions such as schools, universities, or hospitals bringing producers together to establish cooperative or shared infrastructure or invest in equipment that will benefit multiple producers middle-of-the-supply-chain activities such as processing, aggregation, distribution of targeted agricultural product. These include organizations such schools (K-12; colleges/universities), hospitals, food banks, gleaners, food rescue, workplace cafeterias, correctional facilities, farmers markets, and care centers (senior, preschools). For-profit entities operating middle-of-the-supply-chain activities such as processing, aggregation, or distribution of targeted agricultural products, whose activities are primarily focused for the benefit of local and regional producers, and that meet the eligibility requirements of the Small Business Administration (SBA) small business size standards, matched to North American Industry Classification System (NAICS) code. For more information, visit VAAFM.

The California Energy Commission (CEC) is seeking applications to deploy advanced decarbonization and/or grid support technologies at California industrial facilities to promote electrification and reduce GHG emissions produced from the industrial sector. Donor Name: California Energy Commission (CEC) State: California County: All Counties Type of Grant: Grant Deadline: 06/03/2024 Size of the Grant: More than $1 million Grant Duration: Grant Duration Not Mentioned Details: This solicitation will target technologies that have the potential to demonstrate cost-effectiveness and scalable to multiple industrial facilities with potential to increase confidence for adoption. The program’s goal is to deploy cutting-edge, emerging technologies at California industrial facilities to promote electrification and load flexibility, reduce fossil fuel and thermal energy usage, and reduce criteria air pollutants and carbon footprints. This program is open to existing industrial facilities, utilities, equipment manufacturers, energy service companies, project aggregators, and project developers who propose to implement projects in California’s industrial sector. Entities, facilities, and projects that are associated with the production or processing of oil and gas are ineligible. The CEC’s INDIGO Program will assist California’s industrial facilities in achieving the following: Emission Reductions: Adopt electrification and other eligible decarbonization technologies to reduce annual GHG emissions and other criteria air emissions at industrial processing facilities. Electrical Grid Support: Adopt commercially available and emerging technologies needed to support grid reliability, especially during net peak periods. Benefits to Priority Populations: Reduce criteria air pollutants and have direct community engagement and support, especially in low income or disadvantaged communities. Project Focus This solicitation focuses on deploying industrial decarbonization technologies that are cutting-edge emerging technologies. The proposed technology(ies) and project must achieve at least one of the following goals at the industrial demonstration site(s). Additional points could be awarded for meeting multiple goals. Electrify some or all industrial processes Maximize GHG emission reductions Drive scalability and application of project technology to other facilities/industries/processes Reduce electrical demand during net peak periods Provide air pollution benefits to priority populations. Funding Information There is up to $46,200,000 available for grants awarded under this solicitation. The minimum funding amount for each project is $4,000,000. The maximum funding amount is $10,000,0000. Eligibility Criteria  Applications to the INDIGO Program are open to existing industrial facilities located in California and to utilities, equipment manufacturers, energy service providers, aggregators, and developers who are implementing cutting-edge, emerging technologies in California industries. The applicant may include multiple industrial facilities located in California in one application. Food and beverage industries and related support facilities that are receiving funding for the same project, or portions of the same project, from the CEC’s Food Production Investment Program (FPIP) are ineligible for funding from the INDIGO Program or to use funds received from FPIP as match funds. For more information, visit CEC.

The Minnesota Department of Health (MDH) Cardiovascular Health Unit is requesting proposals to connect community and clinical sectors among Minnesota adults especially those from communities disproportionally impacted by cardiovascular disease including Black or African American, American Indian or Alaska Native, and Hmong/Asian American communities, to improve heart health and reduce impacts of heart disease, stroke, and diabetes. Donor Name: Minnesota Department of Health (MDH) State: Minnesota County: All Counties Type of Grant: Grant Deadline: 06/12/2024 Size of the Grant: $10,000 to $100,000 Grant Duration: 3 Years Details: MDH will prioritize grants to organizations that serve communities disproportionally impacted by heart disease including Black/African American, American Indian, and Hmong/Asian American populations. Project proposals will demonstrate how organizations create or enhance existing community clinical linkages to increase referrals to social needs, culturally relevant supports, and/or lifestyle change programs for adults with hypertension, high cholesterol, or other risk of cardiovascular disease. Projects must create or enhance existing community clinical linkage(s) to increase referrals to one or more of the following categories (1, 2 or/and 3) of support for adults in the focus population with hypertension, high cholesterol, or other risk of heart disease: Category 1: Social services and supports that address at least one area where they live, learn, work and play. Category 2: Culturally responsive education and/or support for chronic condition prevention, screening, follow up, and/or self-management. Category 3: Evidence-based lifestyle change programs that address hypertension or high cholesterol. Funding Information Estimated Amount of Awards $60,000 annually. Estimated Annual Award Range $20,000-$60,000. The estimated grant start date is Oct. 1, 2024, and the projected end date is June 30, 2027. Eligibility Criteria Eligible applicants may include, but are not limited to: Clinics or healthcare organizations Community-based organizations Community Health Boards/Local Public Health Nonprofit organizations Faith-based organizations Community Health Boards Tribal governments Social service organizations For more information, visit MDH.

The California Natural Resources Agency is accepting proposals for the California Museum Grant Program. Donor Name: California Natural Resources Agency State: California County: All Counties Type of Grant: Grant Deadline: 05/22/2024 Size of the Grant: More than $1 million Grant Duration: Grant Duration Not Mentioned Details: The intent of this program is to solicit proposals for program projects or capital projects that assist and enhance museums that are deeply rooted in, and reflective of, previously underserved communities. The Museum Grant Program has approximately 27.7 million available and may be awarded over multiple rounds depending on the competitive pool. Funding shall be prioritized for museums severely affected by COVID-19 and that serve historically underserved communities or students subject to Title I of the Federal Elementary and Secondary Education Act. Additionally, projects must meet one of the following priorities: serving pupils and teachers at schools eligible to be served under Part A of Title I of the federal Elementary and Secondary Education Act; serving children in low-income communities; supporting museums in engaging or collaborating with underserved communities; advancing preservation of at-risk cultural and natural collections and historic buildings; improving access; supporting the ethical stewardship of culturally sensitive art and artifacts, including, but not limited to, engaging in consultations with California Indian tribes or repatriation; or educating the public about critical issues affecting Californians. Funding Information Grant proposal requests must be between $50,000 and $500,000 for program projects; and $100,000 to 1 million for capital projects. Eligible Projects  All projects must support at least one of the following to be eligible: capital projects, exhibits, educational programs, outreach programs, public programs, curriculum, publications, marketing and collections care. Applicants must select one of the following project types: Capital project Program project. Eligible Applicants  Public agencies and nonprofit organizations that operate a museum, own a museum, or partner with a museum located in the State of California, may apply. Public agencies are defined as federal agencies, state agencies, cities, counties, districts, association of governments, joint powers agencies or tribal organizations. Federally recognized Native American Tribes, or non-federally recognized Native American Tribes within the State of California are eligible as public agencies. Nonprofit organizations are defined as any nonprofit public benefit corporation that is formed pursuant to the Nonprofit Corporation Law (commencing with Section 500 of the Corporations Code), qualified to do business in California, and qualified under Section 501(c)(3) of the Internal Revenue Code, that has, among its principal charitable purposes, the preservation of historical or cultural resources for cultural, scientific, historic, educational, recreational, agricultural, or scenic opportunities; and must be registered with the California Secretary of State and California Department of Justice, Office of the Attorney General Registry of Charities and Fundraisers. Museums are defined as public or private nonprofit institutions that are organized on a permanent basis for essentially educational or aesthetic purposes and that own or use tangible objects, care for those objects, and exhibit them to the general public on a regular basis. Projects can be proposed for museums of any size and discipline. In general, museums fall within the following categories: art museums and art centers; children’s/youth museums; cultural museums and cultural centers; general museums; history and historical museums (including historical societies, historic preservation organizations, historic houses/sites, and history museums); living collections (such as arboretums, botanical gardens, nature centers, zoos, aquariums, and wildlife conservation centers); and science and technology museums (including planetariums, discovery centers, natural history/anthropology museums and natural science museums). Applicants must also: have the institutional and financial capacity to complete the project and produce the deliverable described in their proposal; be able to demonstrate adequate charter or enabling authority to carry out the type of project proposed; be free of any legal challenges that could undermine progress on the project; and be in compliance and good standing on all previously awarded State grants. For more information, visit CNRA.

Funding available through this RFA supports company formation, as well as early research and development of novel oncology therapeutics, devices, treatment-oriented information technology products, diagnostics, or tools. The objective of the SEED Award program is to start with an interesting technology and to progress it toward a commercially viable business opportunity, i.e., make it more attractive to private funding agents. Typically, applicants have completed the following activities: Identified a novel therapeutic, diagnostic technology, or clinical tool and shown a biological effect Conducted preliminary safety and toxicology testing (in the case of therapeutic agents) Shown the product can be manufactured at small scale or as a prototype Assessed the business opportunity and organized a business plan that begins to address key issues (clinical utility, target market, financial plan, IP strategy, technical challenges, etc.) and lays out a preliminary development plan (formulation, toxicology, scale up, IND-enabling studies, phase 1 clinical trials, regulatory pathway, etc.). Established a company

Funding available through this RFA supports the ongoing research and development of innovative products, services, and infrastructure with significant potential impact on patient care. Generally, at this stage, the company has identified and characterized a lead compound; demonstrated efficacy in multiple translationally relevant animal models; completed pilot/dose ranging toxicology studies; determined the feasibility of a scalable, GMP compliant manufacturing process, including release assays; and identified a prototype formulation suitable for further development. The applicant is typically within one year from filing an IND/IDE or already in Phase 1. With appropriate justification, companies may use CPRIT funds to support the following: Studies that establish preclinical proof of concept (safety and efficacy) CMC/manufacturing development GLP safety studies to support INDs Phase 1 in humans to establish safety and a recommended dose for phase 2 Phase 2 studies to determine safety and efficacy in initial targeted patient population

Funding available through this RFA supports the ongoing research and development of new and emerging technologies for the detection, diagnosis, prognosis, monitoring, or treatment of cancer. CPRIT created this RFA to fund new and emerging technology projects that do not easily fit into any of the three other CPRIT Product Development Research RFAs. Proposals may include, but are not limited to, bioinformatics, artificial intelligence, production of radionuclides or their precursors, manufacture of cell-based therapies, processes to improve the quality of the samples used for cancer research or clinical care, and biomanufacturing of therapeutics. With appropriate justification, companies may use CPRIT funds to support studies that establish preclinical proof of concept, product validation, design, production, manufacturing and development, and clinical studies demonstrating safety and efficacy.

Funding available through this RFA supports the ongoing research and development of diagnostic tests and devices to treat, detect, diagnose, monitor, and assist in the treatment of cancer. Relevant areas include: Devices and assays for cancer detection, diagnosis, prognosis, monitoring, treatment and prediction of response or resistance to treatment Markers for cancer prevention and control, companion diagnostic to a therapy Development of diagnostic tests to distinguish high-risk early lesions Generally, at the time that an applicant applies to CPRIT pursuant to this RFA, the company has developed a commercial prototype of the device or a pictorial representation of the functional components/elements of the device. With respect to diagnostics, the company has developed assays that work on human samples and whose importance is well justified for development into clinical assays. The applicant should be working toward submitting an Investigational Device Exemption (IDE) or a 510(k) or Premarketing Approval (PMA) and is typically within one year from filing an IDE (or later stage work.) Potential applicants that are not at or near this stage of product development should consider applying for a Texas Seed Company Award. With appropriate justification, companies may use CPRIT funds to support studies that establish preclinical proof of concept, product validation, design, production, manufacturing and development, and clinical studies demonstrating safety and efficacy.

The Community Forests Program gives communities a way to preserve their working forest heritage. Donor Name: Washington State Recreation and Conservation Office State: Washington County: All Counties Type of Grant: Grant Deadline: 05/01/2024 Size of the Grant: More than $1 million Grant Duration: Grant Duration Not Mentioned Details: The grant program balances the many benefits forests provide – from providing money from use of the land, to safeguarding against climate and other environmental changes, to providing opportunities for recreation, education, and cultural enrichment.  As Washington’s population continues to grow and forestlands are increasingly threatened by development, the Community Forests Program is a valuable tool for preserving working lands for the benefit of Washingtonians now and into the future. Typical Projects Buying land to conserve working forests (required for all projects). On purchased land, projects also may restore forest and habitat health and develop recreational facilities. Funding Information $3 million is available. Eligible Projects Acquisition: Buying forestland Development: Developing recreation facilities, such as trails and trailheads, parking, restrooms, campgrounds, picnic and day-use areas, challenge courses, interpretive displays. Restoration: Restoring forest health or habitats, planting or reforestation, removing or correcting fish barriers All projects must acquire land. Projects may include restoration or development of that land but restoration and development cannot be stand-alone projects. Who May Apply? Cities, counties, and towns Native American tribes Nonprofit nature conservancy organizations Special purpose districts, public development authorities, or other political subdivisions of the state. State agencies (in partnership with one or more of the above groups). For more information, visit WSRCO.

The New Jersey Department of Environmental Protection is accepting applications for its Solid Waste Recycling Enhancement Act (REA) Higher Education Research Grant Program. Donor Name: New Jersey Department of Environmental Protection State: New Jersey County: All Counties Type of Grant: Grant Deadline: 05/28/2024 Size of the Grant: $500,000 to $1 million Grant Duration: Grant Duration Not Mentioned Details: The purpose is to fund projects that support the objectives of the Recycling Enhancement Act. Proposals may be designed to enhance existing resources, tools, or methodologies or create new resources pursuant to the Recycling Enhancement Act. Grant Limitations Approximately $1M of grant funding has been allocated to this opportunity. Awardees and grant amounts will be selected based on the proposal, selection criteria and funds available to the Department as identified herein. The Department reserves the right to only award a portion of allocated funds or apportion funds among the project areas at the Department’s discretion. Who is Eligible? New Jersey institutions of higher education, may be implemented in conjunction with, or subcontracted or partnered to/with, other entities identified in the application as permitted by law. This funding opportunity is available for projects that support the objectives of the REA. Grants may be awarded under the following criteria:  Recycling demonstration, research, or education, including professional training areas. Qualifications Required for Consideration Grants awarded to successful applicants may cover personnel (salaries/fringe benefits), other direct costs (e.g. supplies, printing, mailings, mileage, contractual) and indirect costs. Indirect, fringe benefits or administrative costs should be estimated using an approved negotiated cost agreement. Entities that do not have such an agreement can elect to charge a rate of 10% of modified total direct costs, if available. Please attach a copy of the negotiated cost agreement (if any) to the application submission. For more information, visit NJDEP.

The Multipurpose Drainage Management grant program provides financial assistance to model, design, and construct projects and practices that will control water volume and rates to protect infrastructure, improve water quality and related public benefits, and mitigate climate change impacts. Donor Name: Minnesota Board of Water and Soil Resources State: Minnesota County: All Counties Type of Grant: Grant Deadline: 06/03/2024 Size of the Grant: $500,000 to $1 Million Grant Duration: Grant Duration Not Mentioned Details: The Multipurpose Drainage Management RFP is now open, with $900,000 in funding available for FY 24. This competitive grant program funds multipurpose drainage management practices, targeting critical pollution source areas to reduce erosion and sedimentation, reduce peak flows and flooding, and improve water quality, while protecting drainage system efficiency and reducing drainage system maintenance for priority Chapter 103E drainage systems. Eligible Projects  Eligible activities can consist of structural practices and projects; non-structural practices and measures, project support, grant management and reporting. Technical and engineering assistance necessary to implement these activities are considered essential and are to be included in the total project or practice cost. Eligibility Criteria This grant program strongly encourages a Chapter 103E drainage authority (County, Joint County Board, or Watershed District) and Soil and Water Conservation District(s) to establish or define a partnership to apply for and use these grant funds. One SWCD or drainage authority partner is eligible to apply on behalf of a partnership, but must verify in the proposal that all the partner(s) are committed to the project. The following entities are eligible: Drainage authorities as defined by Minn. Stat. Chapter 103E Local governments (counties, watershed districts, watershed management organizations, and soil and water conservation districts or local government joint power boards) working under a current State approved and locally adopted local water management plan, comprehensive watershed management plan or soil and water conservation district comprehensive plan. Municipalities are eligible if they: 1) have a water plan that has been approved by a watershed district or a watershed management organization as provided under Minn. Stat. 103B.235; or 2) adopted an approved comprehensive watershed management plan developed under Minn. Stat. 103B.801 Counties in the seven-county metropolitan area are eligible if they have adopted a county groundwater plan under Minn Stat. 103B.255 or county comprehensive plan that has been approved by the Metropolitan Council under Minn. Stat. Chapter 473. For more information, visit BWSR.

The Arizona Department of Health Services (ADHS) Bureau of  Nutrition and Physical Activity (BNPA) administers funds provided by the United States Department of Agriculture (USDA) for the operation of the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) and Breastfeeding Peer Counseling Program (BFPC) for the State of Arizona. The USDA nutrition programs are discretionary, and each provides a specific service to women, infants, and children who are low-income and at nutritional risk. The overall goal of all the USDA Nutrition Programs is to increase food security and reduce hunger by providing eligible participants access to nourishing food and supportive nutrition education. ADHS is working with the counties to provide WIC services, and this opportunity is to provide additional community support as needed.  Financial Notes: N/A

The New York State Department of Labor (NYSDOL) is making up to $3M in Title I Workforce Innovation and Opportunity Act (WIOA) Statewide Activities funding available under the Apprenticeship Expansion Grant (AEG-4) Request for Applications (RFA). The purpose of this RFA is to expand New York State (NYS) Registered Apprenticeship (RA) training by increasing employment opportunities for approximately 130 apprentices, with a focus on underrepresented populations. These apprentices will enter trades in high-demand occupations, with a focus on the emerging fields of Advanced Manufacturing, Healthcare, Hospitality, and Information Technology, as well as other in-demand occupations. Please note that this solicitation focuses on promoting the expansion of NYS RAs and as such, RAs in the field of Construction are not eligible for funding under this RFA unless the trade is to be used for the upkeep and maintenance of a facility owned by the business entity employing the apprentice, such as plant maintenance trades.

The CalMoneySmart program aims to enhance financial empowerment among unbanked and underbanked Californians by funding nonprofit organizations. Through financial education and empowerment services, it seeks to reduce disparities, improve financial literacy, and foster wealth-building opportunities. The program awards grantees up to $200K per year for two consecutive fiscal years to promote financial stability and security statewide. ; Grant funds may only be used for the following financial education and empowerment services for the targeted at-risk unbanked and underbanked populations: 1) Designing, developing, or offering, free of charge to consumers, classroom or web-based financial education and empowerment content intended to help unbanked and underbanked consumers achieve, identify, and access lower cost financial products and services, establish or improve their credit, increase their savings, or lower their debt. 2) Providing individualized, free financial coaching to unbanked and underbanked consumers. 3) Designing, developing, or offering, free of charge to consumers, a financial product or service intended to help unbanked and underbanked consumers identify and access responsible financial products and financial services, establish or improve their credit, increase their savings, or lower their debt. Every project funded with a grant from the Financial Empowerment Fund shall meet the following criteria: 1) Promote and enhance the economic security of consumers. 2) Adhere to the five principles of effective financial education described in the June 2017 report issued by the federal Consumer Financial Protection Bureau titled “Effective financial education: Five principles and how to use them.” Grant awards will be announced for a two-year period covering two consecutive fiscal years. Funds for each fiscal year are disbursed separately and any unexpended funds must be returned to the DFPI. Disbursement of funding for the second fiscal year is contingent on submission of a satisfactory annual report. A mandatory in-person training for grantees will be held during the grant cycle. Final details will be included in the grant agreement.   Grantees may use no more than 15 percent of the grant to cover administrative (indirect) costs. Failure to comply shall render the Applicant ineligible for a grant during the subsequent fiscal year and until the noncompliance is corrected.  A grantee may subcontract services that it has agreed to provide under the grant agreement, so long as those services are conducted on behalf of the grantee. Subcontract arrangements must be clearly described in the scope of work and budget. Accepting grant funds with the intent of distributing those funds to other nonprofit organizations (for example, sub-grants or fiscal sponsorship) is not allowed. Grant funding may not be used for financial incentives for individuals. Prohibited incentives include, but are not limited to, match funding for savings accounts, participant stipends, or gift cards with a cash value. Grantees are required to submit preliminary and final annual reports, in a form and by a date specified by the Commissioner of Financial Protection and Innovation, documenting: 1) The specific uses to which grant funds were allocated, 2) The number of individuals aided through use of the funds, 3) Quantitative results regarding the impact of grant funding, and 4) Any other information requested by the Commissioner. Failure to submit satisfactory reports shall render the Applicant ineligible for any DFPI grant during the subsequent fiscal year and until the required report is submitted. 

Supports applications that propose innovative cancer clinical studies in adults or children and adolescents that are hypothesis driven and involve patients enrolled prospectively on a clinical trial. Areas of interest include clinical studies of new or repurposed drugs, hormonal therapies, immune therapies, surgery, radiation therapy, stem cell transplantation, combinations of interventions, or therapeutic devices. Clinical trial must be planned to begin when contract is awarded.

Supports applications for innovative mathematical and/or computational research projects addressing questions that will advance current knowledge in the (a) mechanisms that tie altered gene expression and downstream molecular mechanisms to functional cancer phenotypes and/or (b) mechanisms that tie tumor morphology to functional cancer phenotypes and/or mechanisms that tie treatment sequence and combination to evolving functional cancer phenotypes (that emerge as a result of treatment selection).

Supports applications which propose clinical and population-based projects designed to develop effective prevention and early detection interventions to reduce cancer risk, mortality, and morbidity among Texans. Projects that propose such research collaborations with existing CPRIT Prevention Program awardees including the CPRIT funded Texas Collaborative Center for Hepatocellular Cancer (https://www.bcm.edu/research/labs-and-centers/research-centers/texas-collaborative-center-for-hepatocellular-cancer) are strongly encouraged.