Texas Income Security and Social Services Grants
Explore 86 grant opportunities
Application Deadline
May 10, 2024
Date Added
Feb 26, 2024
The Texas Indigent Defense Commission (TIDC) has issued the 2025 Improvement Grant Request for Applications (RFA) for programs that improve indigent defense services in Texas. Donor Name: Texas Indigent Defense Commission (TIDC) State: Texas County: All Counties Type of Grant: Grant Deadline: 05/10/2024 Size of the Grant: $10,000 to $100,000 Grant Duration: 1 Year Details: Improvement Grants help counties develop new programs or processes to improve indigent defense. Improvement Grants are competitive, dependent on available funding, and usually require county matching funds. Priority Program Areas Applications for the following program types shall be given funding priority: Managed indigent defense programs structured to ensure quality representation. This includes, but is not limited to, managed assigned counsel and public defender programs. Specialized indigent defense programs representing clients with mental health challenges. Regional indigent defense services. Programs that serve rural areas. Programs that measure the quality of representation for indigent defendants. Indigent defense process management software systems supporting compliance with indigent defense laws. Other programs that implement cost containment initiatives designed to limit local indigent defense cost increases or reduce county operating costs with respect to indigent defense. Improvement Grant Categories Multi-Year Improvement Grants Funding for programs providing indigent defense representation, including public defender offices, managed assigned counsel programs, and indigent defense coordinator programs. Provides funding over four years. Requires a cash match. Grants typically reimburse up to 80% of total approved project costs for the first year; 60% for the second year; 40% for the third year; and 20% for the fourth year. Awards for multi-year grants are made each fiscal year, with funding of eligible expenses provided on a reimbursement basis. Grantees will be required to submit a brief Continued Multi-Year Improvement Grant application form and submit a new Improvement Grant Resolution for continued funding for each subsequent year of eligibility. Minimum $50,000 project budget per application. Rural Regional Public Defender Sustainability Grants Regional programs must cover three or more counties. Counties with populations less than 100,000 are eligible. (Counties that exceed this threshold may request a variance based on special considerations.) Provides reimbursement of 80% of approved program costs in the initial year, transitioning to ongoing sustainability funding covering 2/3 of eligible costs in subsequent years. May be operated directly by counties or contracted to eligible nonprofit public defender organizations. Single-Year Improvement Grants Funding for indigent defense process improvement projects including technology projects. These projects require a cash match as detailed in Section II below. Minimum program budget of $5,000 per application. Routine equipment replacements or upgrades are not eligible. Technical Support Grants Special projects including indigent defense research, program assessments, or pilot projects that build the knowledge base about indigent defense and test processes that can be applied in other counties. All technical support projects require a project paper that describes the implementation, the benefits the county may have received, a brief commentary from participants, and a brief discussion on implications or suggestions for other similar projects. Continued Multi-Year Improvement Grants Counties with current Multi-Year Improvement Grant awards and Rural Regional Public Defender Sustainability Grants must submit a brief online Continued Multi-Year Improvement Grant form for each subsequent year of eligible funding. A new Commissioners Court or governing board resolution must be submitted with the application each year. Requests for scope changes, amendments or budget adjustments may be submitted with Continued Multi-Year applications. Funding Priorities Funding priorities include the following: New public defender offices. New managed assigned counsel systems. Mental health, juvenile, or other specialty defender offices. Indigent defense coordinators. Grant Period Period for Funding and Program Operation: October 1, 2024, to September 30, 2025. Eligibility Criteria The following entities are eligible for Improvement Grants: Texas counties. Counties may apply jointly for funding but must designate one county as the grant recipient. A law school’s legal clinic or program that provides indigent defense services for Texas counties as described in Section 79.037, Texas Gov’t Code. A regional public defender formed under Article 26.044, Code of Criminal Procedure that provides indigent defense services for Texas counties and meets the requirements of Texas Gov’t Code Section 79.037. An entity described by Section 791.013, Texas Gov’t Code that provides to a county administrative services under an interlocal contract entered for the purpose of providing or improving the provision of indigent defense services in the county. A nonprofit corporation that provides indigent defense services or indigent defense support services in a county. Nonprofit applicants must document support from and coordination with the county or counties and courts served. Nonprofit applications should contact TIDC staff early in the application process to provide online grant application account setup and for guidance on documentation of county support and coordination. For more information, visit TIDC.
Application Deadline
Sep 18, 2024
Date Added
Sep 3, 2024
With generous support from the Wells Fargo Foundation, NALCAB will provide capacity building grants of $30,000 and customized technical assistance (TA) to 10 organizations, prioritizing organizations located in Wells Fargo’s priority geographic markets. Donor Name: National Association for Latino Community Asset Builders (NALCAB) State: County: All Counties Type of Grant: Grant Deadline: (mm/dd/yyyy) 09/18/2024 Size of the Grant: $10,000 to $100,000 Grant Duration: Less than 1 Year Details: The primary purpose of this award is to support a nationwide network of Latino- and immigrant-serving organizations to advance culturally relevant approaches to family financial health in low-and moderate-income Latino and immigrant communities. This program of grantmaking, technical assistance and training is intended to strengthen the delivery of financial capability services focused on: Integrating a culturally relevant financial curriculum into asset-building programs like homeownership and small business development services. Intentionally utilizing financial coaching to prepare participants to access capital for asset-building activities. Improving organizational capacity to track and report financial health outcomes, with a focus on improving credit, increasing savings, increasing income, and reducing debt. Prioritizing access to innovative financial products to boost family financial wellness, such as increasing savings, decreasing debt, or building or establishing credit. Wells Fargo Priority Markets: NALCAB will focus on the following priority markets, as communicated by Wells Fargo: Georgia: Atlanta Illinois: Chicago North Carolina: Charlotte Texas: Dallas, Houston California: Los Angeles, San Diego, San Francisco Florida: Miami Tennessee: Nashville New York Pennsylvania: Philadelphia Arizona: Phoenix Missouri: St. Louis Washington, DC Minnesota: Minneapolis Grant Period October 1, 2024 – June 30, 2025. Eligibility Criteria Eligible applicants are any 501(c)(3) nonprofits who integrate, or plan to integrate, culturally relevant financial capability services into existing asset-building programs. Applicants should demonstrate: A comprehensive and specific strategy that will result in meaningful and measurable impact and change for Latino and immigrant financial health. Organizational capacity to implement the proposed strategy. Budget and projected outcomes that align with the proposed strategy. For more information, visit NALCAB.
Application Deadline
Aug 31, 2024
Date Added
Jul 22, 2024
The City of Houston Department of Neighborhoods is seeking applications for its Matching Grant Program to improve Houston neighborhoods. Donor Name: City of Houston State: Texas County: All Counties Type of Grant: Grant | Reimbursement Deadline: 08/31/2024 Size of the Grant: $1000 to $10,000 Grant Duration: Grant Duration Not Mentioned Details: This program is administered in partnership through the City of Houston Department of Neighborhoods and the City of Houston Council Member’s Offices. It is designed to build solid relationships among neighbors, cultivate the spirit of volunteerism, and to develop projects that build a sustainable and stronger community. The goal is simple. They want to improve the quality of life for Houston communities and partner with active residents to: Improve neighborhood organization and pride. Improve community appearance and beautification. Enlist and increase community participation. Funding Information The Matching Grants reimbursement is between $500 to $5,000. Eligible Projects The program helps pay for physical improvements or projects that are accessible and beneficial to the community. The program will not pay for ongoing operation or maintenance such as upkeep of landscaping or a community garden. Proposed projects must meet the following requirements: Improve a neighborhood through a physical improvement. Involve neighborhood residents, have long-standing benefits. Accessible to the public. Letter of permission from property owners and/or government agencies of the proposed site at the time of submittal. The property owner may be a government agency, the owner of private property, or an association if the property is a common area. Proof of ownership of proposed site (Ex: Copy of Deed, HCAD record, etc.) Photo of proposed site. Three letters of support for your project (Ex: Neighborhood or area organizations, businesses, elected officials, schools, super neighborhood council, etc.) If the proposed projects require approval and/or permitting from a City of Houston department, pre-approval from the appropriate city department is required. (Ex: Pre-approvals must be issued by, Parks & Recreation Department for the Adopt-An-Esplanade Program, Public Works & Engineering Department for Subdivision Markers, etc.) The application is ineligible without the pre-approval from the appropriate city department (s). Examples of approved projects include, but are not limited to, street sign toppers, entryway signage, entryway columns, esplanade landscaping and irrigation, park benches, electrical signage, walkways with pavers, murals, etc. Eligibility Criteria Eligible organizations must meet the following criteria: Applicants must be a neighborhood-based organization and/or civic club incorporated as a 501 (c) (3) or 501 (c) (4) non-profit organization through the State of Texas. If the applying neighborhood-based organization is not 501 (c) (3) or 501 (c) (4), they must secure a 501 (c) (3) or 501 (c) (4) organization to partner with for this project. Applicant organizations must represent a specific geographic area located in the Houston city limits. Applicants must Identify how the organization will fund and support the project in the future. Political organizations and individuals are not eligible. For more information, visit City of Houston.
Application Deadline
May 1, 2024
Date Added
Apr 18, 2024
Funding available through this RFA supports the ongoing research and development of diagnostic tests and devices to treat, detect, diagnose, monitor, and assist in the treatment of cancer. Relevant areas include: Devices and assays for cancer detection, diagnosis, prognosis, monitoring, treatment and prediction of response or resistance to treatment Markers for cancer prevention and control, companion diagnostic to a therapy Development of diagnostic tests to distinguish high-risk early lesions Generally, at the time that an applicant applies to CPRIT pursuant to this RFA, the company has developed a commercial prototype of the device or a pictorial representation of the functional components/elements of the device. With respect to diagnostics, the company has developed assays that work on human samples and whose importance is well justified for development into clinical assays. The applicant should be working toward submitting an Investigational Device Exemption (IDE) or a 510(k) or Premarketing Approval (PMA) and is typically within one year from filing an IDE (or later stage work.) Potential applicants that are not at or near this stage of product development should consider applying for a Texas Seed Company Award. With appropriate justification, companies may use CPRIT funds to support studies that establish preclinical proof of concept, product validation, design, production, manufacturing and development, and clinical studies demonstrating safety and efficacy.
Application Deadline
Jul 31, 2024
Date Added
Jul 16, 2024
The City of Harlingen’s Community Development Department is pleased to announce the HOME-ARP Program to provide supportive services to Qualifying Populations. Donor Name: City of Harlingen State: County: All Counties Type of Grant: Grant Deadline: (mm/dd/yyyy) 07/31/2024 Size of the Grant: $100,000 to $500,000 Grant Duration: Grant Duration Not Mentioned Details: The City of Harlingen is seeking qualified service providers to provide supportive services to Qualifying Populations. A total of $287,900.00 will be available through the HOME-ARP Program as funding for Supportive Services. The services are meant to ensure that the needs of those experiencing homelessness or at risk of homelessness are met so that they can obtain and stay in affordable housing. Qualifying Populations are as follows Homeless At risk of Homelessness Fleeing, or attempting to flee, domestic violence, dating violence, sexual assault, stalking or human trafficking– as defined by the U.S. Department of Housing and Urban Development (HUD) Other Populations has moved because of economic reasons 2+ times 60 days immediately preceding the application for homelessness prevention assistance. is living in the home of another because of economic hardship has notification in writing that right to occupy their current housing/living situation will be terminated within 21days after the date of application for assistance lives in hotel/motel and the cost of hotel/motel is not paid by charitable organizations or by federal, state, or local government program for low-income individuals lives in single occupancy or efficiency apartment unit in which there resides more than 2 persons or lives in a larger housing unit in which there are more than 1.5 persons residing per room. is exiting a publicly funded institution, or system otherwise lives in housing that has characteristics associated with instability and an increased risk of homelessness, as identified in the approved HOME-ARP Plan. For more information, visit City of Harlingen.
Application Deadline
Jun 30, 2024
Date Added
Dec 7, 2023
Grant Name: Regional Touring Program Grants Donor: Mid-America Arts Alliance Location: Arkansas, Kansas, Missouri, Nebraska, Oklahoma, and Texas Grant Type: Grant Deadline: Ongoing Grant Size: Up to $5,000 Details: The Regional Touring Program grants by Mid-America Arts Alliance support presenting organizations in showcasing the work of artists from within the M-AAA region. Presenters can receive up to 50% of the artist's fee for booking an artist listed on a state touring roster and up to 25% for booking an artist from the region not listed on a touring roster. Rural presenters may receive an additional 10% of the artist's fee. Projects must engage regional audiences through exposure, interaction, and outreach engagement. Eligible projects must feature in-region artists from outside the presenter's home state and include public-facing events between July 1, 2023, and June 30, 2024. The grant does not cover indirect project costs or expenses associated with benefits or fundraiser events. Eligibility Criteria: Applicant organizations must be tax-exempt non-profit organizations or federally recognized tribal communities incorporated in one or more states in the M-AAA region. They must have a valid EIN and UEI ID and commit to M-AAA's Grantee Assurance of Compliance and Federal Suspension and Disbarment Policy. Organizations may submit a maximum of three applications per fiscal year. For more information, visit M-AAA's website.
Application Deadline
Jun 11, 2024
Date Added
May 13, 2024
This is a competitive renewal, supporting a single Collaborative Action Program to Reduce Liver Cancer Mortality in Texas: Collaborative Action Center (CAP:CAC). • A competitive renewal application will address the expansion of administrative services, resources, and support to funded hepatocellular carcinoma research projects along with strong justification for the continuation of the FY19.2 CAP:CAC award. • Applicants may request a maximum of $3,000,000 in total costs for a period of 5 years. • Multi-Principal Investigators (MIs) are allowed under this Request for Applications (RFA). See the Information for Applicants (IFA) document for definition and eligibility of MIs. • See application limitations for Principal Investigators (PIs)/MIs, regardless of whether the MI is from the prime institution or a subcontracted institution. • Note that CPRIT does not allow the use of the term Co-PI. • Minimum effort for the PI and/or MIs throughout the project period is required. • FY25 salary cap is $225,000 per year. • Competitive renewals are not subject to preliminary evaluation. Renewal applications move directly to the full peer review phase.
Application Deadline
Jul 24, 2024
Date Added
Jun 4, 2024
The National Fish and Wildlife Foundation (NFWF) is seeking proposals for the 2024 Monarch Butterfly and Pollinators Conservation Fund to advance pollinator conservation. Donor Name: National Fish and Wildlife Foundation (NFWF) State: Selected States County: All Counties Type of Grant: Grant Deadline: (mm/dd/yyyy) 07/24/2024 Size of the Grant: $100,000 to $500,000 Grant Duration: 3 Years Details: The goal of the Monarch Butterfly and Pollinators Conservation Fund (Pollinator Fund) is to protect, conserve, and increase habitat for the monarch butterfly and other native insect pollinators. The most competitive projects will demonstrate clear benefits to both monarch butterfly and additional at-risk native insect pollinator species (i.e., federally listed, candidate, or proposed native insect pollinator species). Special consideration will be given to projects benefiting rusty patched bumble bee, Franklin’s bumble bee, Karner blue butterfly, Dakota skipper, Poweshiek skipperling, and Mitchell’s satyr. Categories Grants will be awarded in two categories: Technical Assistance for Private Working Lands Funding in this category will support implementation of technical assistance to increase the number of private landowners voluntarily engaged in monarch butterfly and pollinator conservation practices on private working lands. Up to $2 million is expected to be available for grants ranging from $150,000 to $500,000. Funding will be awarded for projects up to three years in length following finalization of the grant agreement. This category aims to support conservation planning and practice design with private landowners to advance voluntary conservation efforts on working lands that align with NRCS Working Lands for Wildlife frameworks or initiatives, and especially increase Working Lands for Wildlife participation among farmers, ranchers, and forest landowners in the Historically Underserved and Special Emphasis categories. The 2024 Pollinator Fund RFP will support projects that: Direct staff resources to help agricultural producers design and implement conservation practices. Increase Farm Bill program participation and conservation practice implementation among agricultural producers, especially farmers and ranchers in the Historically Underserved and Special Emphasis categories. Funding in this category will support the following two strategies: Hiring additional staff or contractors, based on demonstrated need, including staff to assist private landowners and NRCS with developing pollinator habitat management plans and implementation of new and existing NRCS financial assistance contracts. Targeting outreach to landowners and other partners to prioritize, plan, and deliver financial assistance available through the Conservation Stewardship Program (CSP), Environmental Quality Incentives Program (EQIP), and other Farm Bill programs to improve pollinator habitat and support at-risk pollinator species. Habitat Improvement Funding in this category will support on-the-ground work to increase the quality, quantity, and connectivity of habitat for the monarch butterfly and other native insect pollinators. Up to $3.1 million is expected to be available for grants ranging from $200,000 to $300,000. Funding will be awarded for projects up to two years in length following finalization of the grant agreement. Applicants in this category should define a step-by-step restoration plan including site preparation, equipment used, planting techniques, size of the project area, description of target native plant community, and maintenance plan (e.g., prescribed burning, mowing, grazing schedules). Projects proposed to benefit other at-risk native insect pollinators should specify habitat needs for those species and how the proposed work will support their breeding, nectaring, nesting, or other habitat needs. Funding in this category will support the following two strategies: Restore and enhance pollinator habitat, with an emphasis on regionally appropriate milkweed and a diversity of native nectar plants. Increase native seed and seedling supply, with an emphasis on improving the sustainability and affordability of regionally appropriate, local ecotypes. Program Priorities All proposals must specifically address how the proposed project will directly and measurably contribute to the accomplishment of the Pollinator Fund’s goals as outlined in NFWF’s Monarch Butterfly Business Plan. As such, all proposals must provide the number of acres restored or enhanced as a result of the project. Proposals must include plans to restore or enhance a minimum of 100 acres in California or 500 acres in all other eligible states. Acres may be counted from multiple sites; the sites do not need to be contiguous. Since 2015, successful proposals have included a median of 960 acres and an average of 2,120 acres restored or enhanced. Funding Information The Pollinator Fund will award up to $5.1 million in grants in 2024: up to $2 million for Technical Assistance for Private Working Lands and up to $3.1 million for Habitat Improvement. Funding is provided by Bayer Crop Science, Danone North America, The Scotts Miracle-Gro Foundation, Natural Resources Conservation Service (NRCS), U.S. Fish and Wildlife Service (USFWS), Bureau of Land Management (BLM), and U.S. Forest Service (USFS). Geographical Areas Technical Assistance for Private Working Lands Grant funding will be awarded in the following eligible states: Arkansas, Arizona, California, Idaho, Illinois, Indiana, Iowa, Kansas, Kentucky, Michigan, Minnesota, Missouri, Nebraska, Nevada, New Mexico, New York, Ohio, Oklahoma, Oregon, South Dakota, Texas, Utah, Washington, Wisconsin, and West Virginia. Within eligible states, priority will be given to projects located in the North Core, South Core, West Core, and Overwintering Monarch Conservation Units. Projects are restricted to private working lands. Habitat Improvement Grant funding will be awarded in the following eligible states: Arizona, Arkansas, California, Colorado, Idaho, Illinois, Indiana, Iowa, Kansas, Michigan, Minnesota, Missouri, Montana, Nebraska, Nevada, New Mexico, North Dakota, Ohio, Oklahoma, Oregon, South Dakota, Texas, Utah, Washington, Wisconsin, and Wyoming. Within eligible states, priority will be given to projects located in the North Core, South Core, West Core, and Overwintering Monarch Conservation Units. West of the Rocky Mountains, priority will be given to projects on or adjacent to the following: monarch butterfly overwintering sites, BLM lands, and USFS lands. Eligibility Criteria Eligible and Ineligible Entities: Eligible applicants include nonprofit 501(c) organizations, U.S. federal government agencies, state government agencies, local governments, municipal governments, tribal governments and organizations, and educational institutions. Ineligible applicants include businesses, unincorporated individuals, and international organizations. For more information, visit NFWF.
Application Deadline
Jul 25, 2024
Date Added
Jun 24, 2024
The Health and Human Services Commission (HHSC) seeks qualified Applicants to implement a Nutrition Incentive Program (NIP) Project. The purpose of the NIP Project is to increase the purchase of fruits and vegetables by low-income households participating in the United States Department of Agriculture Supplemental Nutritional Assistance Program (SNAP). Services must be provided in accordance with the specifications contained in this Request for Application (RFA). Applicants should reference Section II, Scope of Grant Project, for further detailed information regarding the purpose, background, eligible population, eligible activities, and requirements.
Application Deadline
Jan 6, 2025
Date Added
Sep 4, 2024
This funding opportunity provides financial support to organizations that deliver high-quality early childhood education and family services to low-income children and families across multiple states in the U.S.
Application Deadline
Jun 11, 2024
Date Added
Apr 8, 2024
Supports applications which propose clinical and population-based projects designed to develop effective prevention and early detection interventions to reduce cancer risk, mortality, and morbidity among Texans. Projects that propose such research collaborations with existing CPRIT Prevention Program awardees including the CPRIT funded Texas Collaborative Center for Hepatocellular Cancer (https://www.bcm.edu/research/labs-and-centers/research-centers/texas-collaborative-center-for-hepatocellular-cancer) are strongly encouraged.
Application Deadline
Not specified
Date Added
Dec 11, 2024
The 2025 Conservation Wrangler program, hosted by Texan by Nature, seeks to accelerate impactful conservation projects led by Texas-based organizations. The program supports up to six selected projects annually that demonstrate measurable benefits to people, prosperity, and natural resources. Selected projects receive 12–18 months of tailored program management and strategic guidance to enhance their reach and effectiveness. Eligible projects must be science-based, Texas-led, and demonstrate tangible conservation outcomes. They should engage diverse audiences and promote partnerships among community, business, and conservation organizations. Examples of eligible focus areas include wildlife, land, and water conservation across Texas geographies, from urban to rural settings. Selected projects are showcased during the annual Conservation Summit, offering visibility and networking opportunities. Participants in the Conservation Wrangler program are not guaranteed funding but gain strategic support such as program management, marketing assistance, content creation, and technical connections. Applicants must commit to collaborative participation, dedicate staff resources to achieve outlined goals, and present their work at the Conservation Summit. Applications are evaluated on a range of criteria, including impact, innovation, and measurable outcomes. The process requires detailed project descriptions, objectives, funding strategies, and impact metrics. Supporting documents, such as budgets, maps, and reports, are encouraged. Applications must be submitted in Word format by January 31, 2025, at 11:59 PM CST. For guidance, applicants can reach out to the program team for consultations before applying.
Application Deadline
Apr 29, 2025
Date Added
Jan 16, 2025
This funding opportunity provides financial support to organizations that deliver high-quality early childhood education and family engagement services for low-income children and their families across multiple states.
Application Deadline
Jun 11, 2024
Date Added
Apr 8, 2024
Supports applications for innovative mathematical and/or computational research projects addressing questions that will advance current knowledge in the (a) mechanisms that tie altered gene expression and downstream molecular mechanisms to functional cancer phenotypes and/or (b) mechanisms that tie tumor morphology to functional cancer phenotypes and/or mechanisms that tie treatment sequence and combination to evolving functional cancer phenotypes (that emerge as a result of treatment selection).
Application Deadline
Not specified
Date Added
Nov 22, 2023
This grant provides financial support to nonprofit organizations in seven Texas counties for projects focused on health care, education, and community services.
Application Deadline
Not specified
Date Added
Nov 22, 2024
This program provides financial support and resources to underserved entrepreneurs in Texas, helping them grow their businesses through training, mentorship, and access to capital.
Application Deadline
Jun 11, 2024
Date Added
Apr 8, 2024
Supports applications for innovative research projects addressing questions that will advance knowledge of the causes, prevention, progression, detection, or treatment of cancer in children and adolescents. Laboratory, clinical, or population-based studies are all acceptable. CPRIT expects the outcome of the research to reduce the incidence, morbidity, or mortality from cancer in children and/or adolescents in the near- or long-term.
Application Deadline
Jun 30, 2025
Date Added
May 21, 2025
This funding opportunity supports nonprofit organizations that provide stable housing and empower low- and moderate-income communities, focusing on vulnerable populations such as working families, youth, seniors, and veterans.
Application Deadline
May 1, 2024
Date Added
Apr 18, 2024
Funding available through this RFA supports company formation, as well as early research and development of novel oncology therapeutics, devices, treatment-oriented information technology products, diagnostics, or tools. The objective of the SEED Award program is to start with an interesting technology and to progress it toward a commercially viable business opportunity, i.e., make it more attractive to private funding agents. Typically, applicants have completed the following activities: Identified a novel therapeutic, diagnostic technology, or clinical tool and shown a biological effect Conducted preliminary safety and toxicology testing (in the case of therapeutic agents) Shown the product can be manufactured at small scale or as a prototype Assessed the business opportunity and organized a business plan that begins to address key issues (clinical utility, target market, financial plan, IP strategy, technical challenges, etc.) and lays out a preliminary development plan (formulation, toxicology, scale up, IND-enabling studies, phase 1 clinical trials, regulatory pathway, etc.). Established a company
Application Deadline
May 1, 2024
Date Added
Apr 18, 2024
Funding available through this RFA supports the ongoing research and development of innovative products, services, and infrastructure with significant potential impact on patient care. Generally, at this stage, the company has identified and characterized a lead compound; demonstrated efficacy in multiple translationally relevant animal models; completed pilot/dose ranging toxicology studies; determined the feasibility of a scalable, GMP compliant manufacturing process, including release assays; and identified a prototype formulation suitable for further development. The applicant is typically within one year from filing an IND/IDE or already in Phase 1. With appropriate justification, companies may use CPRIT funds to support the following: Studies that establish preclinical proof of concept (safety and efficacy) CMC/manufacturing development GLP safety studies to support INDs Phase 1 in humans to establish safety and a recommended dose for phase 2 Phase 2 studies to determine safety and efficacy in initial targeted patient population