Grants for Special district governments - Food and Nutrition

This Notice of Funding Opportunity (NOFO) is issued by the Food and Drug Administration (FDA), Center for Veterinary Medicine (CVM), and solicits Research Project (R01) grant applications from institutions or organizations that propose to develop or support the development of designated new animal drugs intended for minor uses in major species or for use in minor species (MUMS). The FDA is authorized to provide grants to assist in defraying the costs of qualified safety and effectiveness testing that could be used to satisfy the requirements for FDA approval of MUMS-designated drugs.Only entities developing drugs for veterinary use or parties working as research partners with such entities are eligible for grants.The organization (or applicant) seeking approval of the new animal drug under investigation must have opened an Investigational New Animal Drug (INAD) file with FDA/CVM and must hold a minor use or minor species "designation" granted by FDA/CVM's Office of Minor Use and Minor Species Animal Drug Development (OMUMS) for that drug for a specified intended use, in accordance with the provisions of section 573 of the Food, Drug and Cosmetic Act (21 U.S.C. 360ccc-2) and 21 CFR part 516.FDA/CVM's Office of New Animal Drug Evaluation (ONADE) must have reviewed and concurred with the proposed study protocol before an applicant can submit a grant application.

This funding opportunity is designed to establish a center that will coordinate and advance research on whole person health by integrating diverse biomedical knowledge and fostering collaboration among researchers.

The "Type 1 Diabetes TrialNet Clinical Network Hub" grant aims to support the coordination unit for clinical trials focused on preventing and intervening early in type 1 diabetes, by improving communication, outreach, and developing new strategies for better screening, recruitment, and retention of participants.

This grant provides funding for interdisciplinary research teams to explore the neural and behavioral aspects of benign urological conditions, aiming to improve understanding and treatment of these diseases.

The purpose of the Mentored Quantitative Research Career Development Award (K25) is to attract to NIH-relevant research those investigators whose quantitative science and engineering research has thus far not been focused primarily on questions of health and disease. The K25 award will provide support and "protected time" for a period of supervised study and research for productive professionals with quantitative (e.g., mathematics, statistics, economics, computer science, imaging science, informatics, physics, chemistry) and engineering backgrounds to integrate their expertise with NIH-relevant research. This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA.

The purpose of this program is to support projects that will treat invasive plant infestations that threaten forested, woodland, or rangeland areas. The theme for the FY 2024 funding cycle is grasses and grasslands. Projects may occur on state, federal, tribal, and private lands in Arizona.  This program focuses on the prevention, control/removal, and eradication of invasive plants and aims to achieve the following objectives: Target and treat invasive plants that are capable of transforming native plant communities in forests, woodlands, deserts, or rangeland Assist in preventing fire and flooding, conserving water, and restoring habitat to wildlife Use an integrated weed management (IWM) approach when treating areas infested with invasive plants through the utilization of available tools, including manual, cultural, mechanical, chemical, and biological control methods Examples of eligible projects include: Control/removal or eradication of invasive plants Replacement of invasive plants with native plants through reseeding and planting Removal of woody invasive plant slash by mulching or grinding Examples of eligible costs include those in the following categories: Administrative labor Project labor Fringe benefits Travel Equipment Supplies Contractual Financial Notes: Match Notes: Applicants must provide at least 10 percent of the total project costs via cash and/or in-kind contributions. Priority may be given to projects that provide a higher-than-required match amount, not to exceed 50 percent. Specifically allowable matching contributions include: Cash paid by award recipients In-kind expenses, including necessary costs incurred by award recipients or other organizations to support the project Volunteer hours at a reasonable rate Donated labor and/or equipment necessary to complete the specific project Physical work performed by individual landowners on their own property Funding Notes: A total of $970,000 is available to support awards ranging from $50,000 to $200,000 through this program. Funds will be provided on a reimbursement basis. Awards are expected to be issued in fall and winter 2024/2025. Specifically, award announcements are expected around October 2024. Proposed projects should be ready for implementation upon receipt of award and should be fully achievable within the prescribed award period. Projects must be considered shovel-ready. Funds may not be used for: Research and development projects Website, geographic information system (GIS), and database projects Projects that only include assessment activity and no related treatment of invasive plants Projects that include purchase of capital equipment valued at over $5,000 per item Expenses incurred prior to execution of a formal written agreement between the funding agency and the award recipient Reimbursement of physical work performed by individual landowners on their own property Food or beverage purchases

This funding opportunity provides financial support to researchers with active NIH grants to address unexpected costs and enhance their projects without changing the original research scope.

This funding opportunity supports research that explores the effects of aging on individuals living with HIV, focusing on improving health outcomes and management strategies for this population.

This funding opportunity supports multi-site clinical trials aimed at testing high-risk medical interventions for diseases related to diabetes, digestive disorders, and kidney health, targeting a wide range of eligible organizations including universities, nonprofits, and businesses.

This funding opportunity supports U.S.-based organizations in evaluating the impact of upcoming public policies and programs that aim to improve health behaviors and reduce chronic disease risk factors through behavioral changes.

This funding opportunity supports U.S.-based researchers and organizations in developing non-addictive pain relief therapies to combat the opioid crisis, with a focus on advancing preclinical candidates toward clinical trials.

This grant provides funding to support early-career researchers from diverse backgrounds as they transition from mentored postdoctoral positions to independent faculty roles in biomedical research.

This funding opportunity provides financial support to a single institution to establish a central coordinating site that will enhance collaboration and resource sharing among researchers focused on Polycystic Kidney Disease.

This funding opportunity provides financial support for early-stage researchers in the U.S. to explore innovative studies on HIV-related health issues, such as comorbidities and coinfections, with the potential to transform understanding and treatment in this field.

The purpose of the NIH Pathway to Independence Award (K99/R00) program is to increase and maintain a strong cohort of new and talented, NIH-supported, independent investigators. This program is designed to facilitate a timely transition of outstanding postdoctoral researchers with a research and/or clinical doctorate degree from mentored, postdoctoral research positions to independent, tenure-track or equivalent faculty positions. The program will provide independent NIH research support during this transition in order to help awardees to launch competitive, independent research careers.

This funding opportunity provides financial support for small clinical trials focused on preventing and treating diseases related to diabetes, digestive, kidney, and urologic health, particularly targeting underserved populations to improve health outcomes.

This funding opportunity supports researchers and organizations developing innovative therapeutic leads for diseases related to diabetes, digestive, and kidney health, focusing on early-stage preclinical validation to advance potential treatments not currently pursued by major pharmaceutical companies.

This funding opportunity supports clinical research to explore and validate new non-invasive brain stimulation techniques for treating substance use disorders, targeting a wide range of eligible applicants including universities, nonprofits, and businesses.

The "Coordinating Center for Type 1 Diabetes TrialNet" grant aims to fund the TrialNet Coordinating Center, which conducts research, trials, and studies to prevent the progression of type 1 diabetes and preserve insulin production, while also managing data, samples, and network operations, and promoting diverse perspectives in its work.

Computational fluid dynamics (CFD) has played a crucial role in providing an alternative bioequivalence (BE) approach for generic orally inhaled drug products (OIDPs), in addition to comparative clinical endpoint or pharmacodynamic BE studies, as a relatively cost- and time-efficient complement to benchtop and clinical experiments that has been widely used in developing and assessing generic inhaler devices. However, despite the advances in the power of modern computers, there are still some bottlenecks in using CFD due to computational time, limited grid resolution, pre- and post-processing of large simulation data sets, model parameter estimations, and uncertainty quantifications. Machine learning (ML) has been gaining more attention as a potential tool to alleviate such limitations that arise in CFD. The purpose of this grant is to develop a methodology to integrate ML with CFD models of OIDPs to promote alternative BE studies to enhance and accelerate the development and approval of generic OIDPs.