Grants for Native American tribal organizations - Health

This funding opportunity provides support for the ongoing development and maintenance of valuable informatics tools and resources that enhance cancer research and management, benefiting researchers and the broader cancer community.

The purpose of the NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is to provide support to mid-career health-professional doctorates for protected time to devote to patient-oriented research (POR) and to act as research mentors primarily for clinical residents, clinical fellows and/or junior clinical faculty. Section I. Funding Opportunity Description The overall goal of the NIH Research Career Development program is to help ensure that a diverse pool of highly trained scientists is available in appropriate scientific disciplines to address the Nation's biomedical, behavioral, and clinical research needs. NIH Institutes and Centers (ICs) support a variety of mentored and non-mentored career development award programs designed to foster the transition of new investigators to research independence and to support established investigators in achieving specific objectives. Candidates should review the different career development (K) award programs to determine the best program to support their goals. More information about Career programs may be found at the NIH Extramural Training Mechanisms website. The NIH Midcareer Investigator Award in Patient-Oriented Research (K24) is designed to enable mid-career clinician-scientists to: Devote more time to augment their capabilities in Patient-Oriented Research (POR); and Provide mentoring to junior clinical investigators in the conduct of POR (see below for definition). The K24 award is intended to provide protected time to mid-career clinical investigators to provide mentoring to junior clinical investigators, particularly K23 grantees, in POR and to stabilize the careers of these investigators. The intent is to allow these investigators to continue to conduct POR and be available as mentors in POR. It is expected that K24 recipients will obtain new or additional independent, peer-reviewed funding for POR as PD/PI and establish and assume leadership roles in collaborative POR programs. In addition, it is expected that there will be an increased effort and commitment to act as a mentor to beginning clinician investigators in POR to enhance the research productivity of both the K24 investigator and increase the pool of well-trained clinical researchers of the future. For the purposes of the K24 award, Patient-Oriented Research is defined as research conducted with human subjects (or on material of human origin such as tissues, specimens and cognitive phenomena) for which an investigator (or colleague) directly interacts with human subjects. This area of research includes: (1) mechanisms of human disease; (2) therapeutic interventions; (3) clinical trials, and; (4) the development of new technologies. Excluded from this definition are in vitro studies that utilize human tissues but do not deal directly with patients. In other words, patient-oriented research is research in which it is necessary to know the identity of the patients from whom the cells or tissues under study are derived. Studies falling under Exemption 4 for human subjects research are not included in this definition. See also the NIH Director's Panel on Clinical Research Report. NIH defines a clinical trial as "A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes." (NOT-OD-15-015). NIH not only supports trials of safety and efficacy, it also supports mechanistic exploratory studies that meet the definition of a clinical trial and are designed to explore or understand a biological or behavioral process, the pathophysiology of a disease, or the mechanism of action of an intervention. These studies may focus on basic and/or translational discovery research in healthy human subjects and in human subjects who are affected by the pathophysiology of diseases and disorders. By addressing basic questions and concepts in biology, behavior, and pathophysiology, these studies may provide insight into understanding human diseases and disorders along with potential treatments or preventive strategies. NIH also supports biomarker studies that meet the definition of a clinical trial and that may provide information about physiological function, target engagement of novel therapeutics, and/or the impact of therapeutics on treatment response. NIH thus supports studies that meet the definition of clinical trials (as noted above) but do not seek to establish safety, clinical efficacy, effectiveness, clinical management, and/or implementation of preventive, therapeutic, and services interventions. Note: This Funding Opportunity Announcement (FOA) is designed specifically for applicants proposing to serve as the lead investigator of an independent clinical trial, a clinical trial feasibility study, or a separate ancillary clinical trial, as part of their research and career development. Applicants not planning an independent clinical trial, or proposing to gain research experience in a clinical trial led by another investigator, must apply to companion FOA Special Note: Because of the differences in individual Institute and Center (IC) program requirements for this FOA, prospective candidates are strongly encouraged to consult the Table of IC-Specific Information, Requirements and Staff Contacts, to make sure that their application is appropriate for the requirements of one of the participating NIH ICs. See Section VIII. Other Information for award authorities and regulations. Section II. Award Information Funding Instrument Grant: A support mechanism providing money, property, or both to an eligible entity to carry out an approved project or activity. Application Types Allowed New Resubmission Revision Renewal The OER Glossary and the SF424 (R&R) Application Guide provide details on these application types. Only those application types listed here are allowed for this FOA. Clinical Trial? Required: Only accepting applications that propose an independent clinical trial(s) Need help determining whether you are doing a clinical trial? Funds Available and Anticipated Number of Awards The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications. Award Budget Award budgets are composed of salary and other program-related expenses, as described below. Award Project Period The total project period may not exceed 5 years.

This grant provides funding for research on behavioral sleep interventions aimed at improving sleep and mental health outcomes for adolescents and young adults, particularly those from underserved populations.

This funding opportunity provides $1.25 million each to organizations that develop and implement innovative strategies to prevent falls among older adults and individuals with disabilities through community-based programs.

This funding opportunity provides financial support for research sites to study Type 1 diabetic nephropathy by recruiting patients, conducting kidney biopsies, and collecting data to identify new treatment targets and improve precision medicine approaches.

This funding opportunity supports nonprofit organizations and public agencies in their efforts to combat poverty through community empowerment and sustainable solutions in areas such as economic opportunity, education, and environmental stewardship, with a focus on advancing racial equity and serving underserved communities.

Substance use needs to be better incorporated into interventions for the engagement and retention of sexual minority persons in prevention and care with attention to emergent interventions such as long-acting PrEP. Social determinants of health associated with HIV and problematic substance use such as homelessness and criminal justice involvement also demonstrate disproportionate impact among sexual and gender minorities and need attention. Changing self-definition of sexual minority status has implications for outreach and provider stigma and needs to be better integrated into interventions. This initiative will address these gap areas and support epidemiologic, intervention, and implementation research that incorporates attention to HIV as a syndemic including comorbidities such as STIs, HCV, and psychiatric disorder.

This grant provides funding to U.S. institutions to foster collaboration and support early-career researchers in benign urology through training, resource sharing, and professional development opportunities.

This funding opportunity supports a central coordinating center that will enhance collaboration and provide resources for research in nonmalignant hematology, particularly aimed at fostering the development of junior investigators and innovative projects across multiple institutions.

This funding opportunity supports innovative research projects that aim to improve the use of genomic information in clinical care, particularly for diverse and underrepresented populations, while addressing health disparities and enhancing the integration of genomic medicine into healthcare practices.

This funding opportunity provides financial support for research on the role of inflammasomes in the brain related to HIV and substance use disorders, targeting innovative studies that explore their impact on inflammation and neurocognitive health.

This grant provides funding for interdisciplinary research teams to explore the ethical implications of new neurotechnologies and brain science advancements, focusing on issues like data privacy, informed consent, and public attitudes toward brain research.

The purpose of this program is to advance the implementation of high quality, evidence-based treatment for individuals with co-occurring physical and mental health conditions, including substance use disorders. Data demonstrate that individuals with mental health conditions are far more likely to also experience physical health conditions. The co-occurrence of these conditions necessitates the delivery of holistic, integrated care. The goal of this grant is to ensure that these services are provided in the most effective manner possible.

This funding opportunity supports the development of innovative medical devices aimed at diagnosing and treating pain or opioid use disorder, targeting researchers and organizations focused on non-addictive solutions in healthcare.

With this solicitation, OJJDP seeks applications for funding to support cross-system collaboration to improve responses and outcomes for youth under the age of 18 or youth under the jurisdiction of the juvenile justice system with mental health disorders (MHD) or co-occurring mental health and substance use disorders (MHSUDs) who come in contact with the juvenile justice system. This program supports public safety efforts through partnerships with youth justice, mental health, and substance use agencies to enhance responses to justice-involved youth with MHD and MHSUDs.

This grant provides funding to organizations that will coordinate statewide meetings to develop strategies for engaging and connecting individuals with HIV to essential healthcare services.

This funding opportunity supports innovative researchers and teams in the U.S. who propose groundbreaking projects that could significantly advance biomedical and social sciences, without the need for preliminary data.

USAID/India cordially invites local Indian organizations to the first In-Person Industry Day which will be held in New Delhi (venue will be provided via individual invitation) on Friday, March 17, 2023, from 9:00 am to 4:00 pm India Standard Time. Specifics for future Industry Days to be held in Mumbai, Bangalore, and Kolkata will be provided in a separate notice. About the Community of Practice The YP2LE Learning Network brings together diverse stakeholders who seek to learn more and share about youth development. As one of seven communities of practice, the Youth Engagement group (YE) helps members share and benefit from collective learning. Learn more about the YE CoP and other CoPs on YouthPower.org and register to connect with these communities. You must be a registered member of YouthPower.org in order to participate in the discussion group. Register today! About YouthPower 2: Learning and Evaluation (YP2LE) YP2LE is a USAID-funded activity focused on building and disseminating evidence on Positive Youth Development (PYD). YP2LE’s goal is to give program implementers, researchers, and young changemakers the information, tools, and resources they need to develop high-quality, impactful, and sustainable youth programs.

The "Catalyze: Product Definition Device Prototype Testing and Design Modification, Diagnostic Disease Target Assay Development and Design Characterization, and Research Tool Testing and Validation" grant aims to provide early-stage funding for the development and testing of prototypes, diagnostic disease target assays, and research tools to improve the treatment of HLBS diseases and disorders, with the goal of advancing these projects to a stage where they can attract further development support.

This grant provides funding to educational agencies and community organizations to improve mental health and substance use services for school-aged youth through collaborative support systems.