Grants for Nonprofits - Health

The Blue Cross Blue Shield of Michigan and Blue Care Network are offering the Step Up for School Wellness (SUFSW) grant, an innovative program designed to empower school health leaders, educators, administrators, families, and communities. This initiative aims to improve the health and well-being of K-12 students and staff across all public, charter, or private nonprofit schools in Michigan. The program aligns with the foundation's mission by fostering healthier school environments and cultivating a culture of wellness, which directly contributes to the development of lifelong healthy behaviors. The primary beneficiaries of this program are K-12 students and school staff throughout Michigan. The program's core impact goals revolve around reducing the incidence of obesity and undernourishment, combating absenteeism, addressing trauma, and nurturing a more productive teaching and learning atmosphere. Through a five-step model, the SUFSW program translates into specific goals focused on improving knowledge, attitudes, and behaviors related to health and wellness. The program prioritizes several key areas, including empowering students to be more physically active daily and make healthy food choices that incorporate fruits, vegetables, low-fat dairy, whole grains, and lean protein. Furthermore, it aims to empower students to learn and practice social and emotional skills, and equip staff to implement and participate in well-being initiatives. A significant focus is also placed on encouraging staff to instigate policy, system, and environmental changes that bolster the well-being of both students and staff within schools. Expected outcomes include improved physical activity levels, healthier eating habits, enhanced social and emotional skills among students, and a stronger culture of wellness for all school employees. The program also anticipates policy and environmental changes within schools that support overall well-being. These measurable results are driven by three distinct focus areas: physical activity and physical education resources, healthy eating and nutrition education resources, and well-being resources, all working towards a greater collective impact.

This funding opportunity supports researchers in developing small molecule chemical probes to investigate biological processes related to mental health, aging, drug addiction, and eye diseases.

The purpose of this initiative is to: 1.Support mining of SCORCH data to identify cell types, transcripts, enhancers, or transcriptional networks that play a role in HIV/ART or SUD molecular responses 2.Support functional validation studies (e.g. epigenomic or transcriptomic manipulation, high throughput secondary screening, etc.) to confirm or deny a biological role for data-mined cell types, transcripts, enhancers, or transcriptional networks in HIV/ART or SUD molecular responses 3.Provide foundational knowledge for understanding SUD and/or HIV/ART molecular mechanisms and to generate validated targets that could serve as a foundation for new SUD or HIV therapeutics (including NeuroHIV cognitive phenotypes)

The Harry S. Black & Allon Fuller Fund is dedicated to supporting quality health care and human services programming for underserved populations. This grant program aligns directly with the foundation's mission to address critical needs in communities, specifically focusing on improving access to essential services for those who face significant barriers. The fund's strategic priorities are rooted in the belief that robust health care and human services are fundamental to individual well-being and community strength. The primary target beneficiaries of this grant program are underserved populations within the city limits of New York City and Chicago. This includes low-income communities requiring health care access, health education, and health policy advocacy, as well as physically disabled individuals who need access programs, disability policy advocacy, workforce development, and initiatives to enhance their quality of life. The impact goals are to foster healthier, more equitable communities by empowering individuals through improved access to vital resources and support. The grantmaking focus areas clearly define the fund's priorities. In health care, the fund supports access, education, and policy analysis and advocacy, with a specific emphasis on programs serving low-income communities. For physical disabilities, the fund prioritizes access programs, disability policy analysis and advocacy, workforce development, and programs that improve the quality of life for disabled individuals. These areas reflect a comprehensive approach to addressing systemic inequities and promoting inclusive community development. While specific expected outcomes and measurable results are not explicitly detailed in the provided information, it can be inferred that the fund seeks to achieve tangible improvements in the health and well-being of the target populations, increased access to services for the physically disabled, and greater equity through policy advocacy and workforce development. The foundation's theory of change appears to be that by strategically investing in organizations that provide direct services and advocate for systemic change, they can create a lasting positive impact on the lives of underserved individuals in their designated geographic areas.

This funding opportunity supports Long Beach community organizations and residents in hosting free summer events focused on violence prevention, intervention, and healing to strengthen neighborhood ties and promote well-being.

This funding opportunity supports innovative research to measure brain changes over time in people of all ages, including those with cognitive or emotional challenges, to better understand brain development and aging.

The Ripley County Community Foundation has a variety of available grants to benefit nonprofit organizations and their projects that serve Ripley County. The grants program strives to anticipate the changing needs of the community and be flexible in responding to them. It focuses on providing "seed" money or pilot project support, but general operating support grants could also be considered. The program aims to have the greatest benefit per dollar granted and encourages the participation of other contributions through matching, challenge, and other grant techniques. The financial condition of the applying organization will be considered, as well as its strength, community support, leadership, clarity of proposal, and eligibility. To be eligible for these grants, organizations must be a nonprofit operating in Ripley County. Grant applications must qualify as an exempt organization under Internal Revenue Code Section 501(c), or be sponsored by such organizations, or qualify as governmental or educational entities with similar attributes per IRS Code Section 509(a). The purpose of the organization's grant application must fall within one or more of the Community Foundation's four service areas: Arts & Culture, Business & Entrepreneurship, Education, Health & Well-Being, and Environment & Natural Resources. Grants will only be made to organizations that have responsible fiscal sponsors and adequate accounting procedures. Grant recipients and fiscal sponsors must sign and abide by the respective conditions set forth in the Community Foundation's "Grant Award Agreements" and "Grant Report Forms". Organizations or their fiscal sponsors cannot have an outstanding or delinquent Grant Report in order for an application to be considered for future granting. The Large Projects Grants specifically provide assistance for sizable projects needed to support and/or enhance an organization's charitable reach. Nonprofit organizations that serve Ripley County can apply for a maximum request of $5,000.00. The application deadline is August 4th. It is important to note that previous awarded grants must be spent and accounted for before applying for another grant from the Ripley County Community Foundation. No grants will be made to defray travel or lodging expenses, for endowment purposes, for completed programs or already purchased equipment, for the acquisition of weapons or firearms, or exclusively for sectarian religious purposes. The foundation reserves the right to refuse any and all grant applications.

This funding opportunity supports partnerships between institutions serving underserved populations and cancer research centers to improve cancer research, education, and outreach initiatives aimed at reducing health disparities.

This funding opportunity supports researchers and institutions in validating high-quality biomarkers and assays for cancer detection, diagnosis, and treatment monitoring, facilitating their integration into clinical studies.

This funding opportunity supports experienced laboratory scientists engaged in cancer research within NCI-funded projects, providing salary support and travel funds to enhance their contributions without requiring them to become independent investigators.

The Texas Health and Human Services Commission (HHSC), the System Agency, is accepting Applications for the Rural Mental Health Initiative Grant Program (RIGP) as directed by Senate Bill 1677, 88th Legislature, Regular Session, 2023. Through the Rural Mental Health Initiative Grant Program, HHSC will award grants to Rural serving Local Mental Health Authorities (LMHAs), Local Behavioral Health Authorities (LBHAs), nonprofit organizations, or governmental entities to be matched in accordance with the specifications outlined in Section 5.4., to address the mental health needs of individuals with mental illness or serious emotional disturbance residing in Rural Texas in accordance with the specifications contained in this Request for Application.

This funding opportunity provides financial support for early-career researchers in genomics to advance innovative projects that contribute to the field and promote diversity within the research community.

This funding opportunity provides financial support to U.S.-based organizations conducting health equity research that has been disrupted by federal funding cuts, prioritizing projects led by early- to mid-career researchers from historically underrepresented backgrounds.

The primary purpose of the NIH Mentored Clinical Scientist Research Career Development Awards (K08) program is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program represents the continuation of a long-standing NIH program that provides support and "protected time" to individuals with a clinical doctoral degree for an intensive, supervised research career development experience in the fields of biomedical and behavioral research, including translational research.

Notice of Funding Opportunity Description Background The accumulation of misprocessed and aberrant proteins is a defining characteristic of various neurodegenerative conditions, such as AD and frontotemporal lobar degeneration (FTLD). These atypical proteins may arise from various factors, such as somatic mutations, environmental changes, genomic instability, irregular RNA processing, and proteolytic cleavages, as well as incorrect folding and post-translational modifications. For instance, many recent proteome and transcriptome profiling of AD brains reveals RNA splicing dysfunction and abnormal accumulation of U1 small nuclear ribonucleoprotein (snRNP) and transactive response DNA-binding protein 43 (TDP-43). In AD, U1-70K and its N-terminal 40-KDa fragment (N40K) is one of the most abundant proteins in the insoluble fraction of cell lysates. TDP-43 is an RNA-binding protein. In AD, TDP-43 pathology is observed in approximately 25-50% of cases, particularly in cases with co-morbidities such as Lewy body dementia or hippocampal sclerosis. However, the relationship between U1snRNP/TDP-43 and AD pathology is complex and not fully understood. The disruption of RNA processing is thought to be one possible mechanism to cause the accumulation of misprocessed proteins, which can lead to altered expression of genes involved in AD pathology, including amyloid precursor protein (APP), tau, and synaptic proteins. Understanding the mechanisms underlying the dysregulation of misprocessed proteins in neurodegenerative diseases will be important for developing effective therapies. Approaches that target the production or aggregation of misprocessed proteins, or that promote their clearance or degradation, may be effective in preventing or slowing disease progression. Purpose This NOFO invites innovative research proposals to explore the accumulation of misprocessed proteins in Tauopathies within specific brain regions and cell types. This NOFO encourages collaborative efforts to create advanced single-cell or single-cell type proteogenomic platforms. These platforms aim to shed light on dynamic changes in protein-misfolding responses in neuronal proteomes and their potential biological consequences during aging and the development of AD/ADRD. Research Objectives This NOFO aims to provide a proof-of-principal for a novel strategy to identify misprocessed and aberrant proteins in Tau diseases using the proteogenomic approach. Proteogenomics is an integrated approach that combines proteomics and genomics data. In proteogenomics, genomic and transcriptomic experiments are more closely integrated to identify potential protein coding and non-coding regions in the genome. These regions are then validated using mass spectrometry-based proteomics. Proteogenomics has emerged as a powerful tool for investigating the role of protein homeostasis in AD pathogenesis, especially in the context of mis-translated and mis-repaired proteins. However, relying solely on misprocessed protein levels to draw conclusions about biological processes is unlikely to be reliable. Therefore, an intermediate layer of functional validation is essential to transform proteogeomic data into meaningful biological information. As a result, the objective of this NOFO is not only to confirm changes in protein abundance using other methods, but also to assess the biological effects of those changes in some model systems, especially in the area of tauopathies, to ensure high interlaboratory reproducibility. Using the proteogenomics approach, this NOFO aims to accomplish the following: Create a comprehensive database of misprocessed and aberrant proteins in selected mouse models of human Tau diseases. Cross-validate the presence of misprocessed and aberrant proteins in human AD/ADRD brains. Identify new molecular pathways and novel misprocessed protein-protein interaction networks that are not currently in most datasets. Define novel mechanisms through which misprocessed and aberrant proteins influence the onset and progression of neurodegeneration in tauopathies. Identify disease specific therapeutic targets in neurodegenerative diseases. It is expected that applications responding to this initiative will use the latest cell-type-specific labeling and proteogenomic techniques with suitable model systems to understand the etiology of tauopathies in aging and AD.

Through Illinois General Review Funds, funds will be appropriated for expenses related to Suicide Prevention, Education, and Treatment Program pursuant to Public Act 101-0331. The Illinois Department of Public Health (IDPH) will provide funding to expand the implementation of strategies in the Illinois Suicide Prevention Strategic Plan. At the recommendation of the Illinois Suicide Prevention Alliance (ISPA), the IDPH Violence and Injury Prevention Section will provide funding to one entity for the purpose to organize and implement workforce development opportunities through implementing the ECHO approach, a Community of Practice (CoP), and offering evidence-based trainings to build workforce development for professionals.

This funding opportunity provides financial support to community-based organizations in Minnesota to deliver job training, mentorship, and entrepreneurial skills development for individuals from communities of color and low-income backgrounds, focusing on high-growth industries.

The L&M Medical Needs Fund Grants, offered by the Community Foundation of Greene County, provide financial assistance for medical needs in Greene County, Pennsylvania. Funded by an endowed gift from an anonymous donor, these grants are available to nonprofit charitable organizations serving individuals in need of medical services, such as prescriptions, hospice care, and other medical services. Eligibility is limited to 501(c)(3) organizations in good standing with the IRS and registered with the Pennsylvania Bureau of Charitable Organizations. The grants focus on aiding individuals who struggle to afford medical services due to being uninsured or facing high costs not covered by insurance. While priority is given to lower-income families, other cases with well-documented need may also be considered. Grant amounts vary annually. Grant renewed every year. Grant Spring Annual deadline: June 1st

This funding opportunity supports researchers exploring the mechanisms of Treponema pallidum, the bacteria responsible for syphilis, to address the rising rates of sexually transmitted infections and improve understanding of its pathogenesis.

This grant provides funding for research projects that test strategies to reduce suicide risk by promoting safe storage of lethal means, such as firearms, in healthcare and community settings.